Heart Disease: From Psychosocial to Pathophysiological to Treatment with Biofeedback—An Overview

Biofeedback ◽  
2013 ◽  
Vol 41 (1) ◽  
pp. 39-42
Author(s):  
Jan B. Newman

Emotions have been connected to the heart throughout the ages, yet they have been largely discounted as playing an important role in heart disease. There is mounting evidence that anxiety, anger, depression, and stress play significant contributing roles in cardiac diseases. These emotional states, coronary artery disease, and heart failure have physiology consistent with the ongoing stress response characterized by parasympathetic withdrawal and sympathetic activation. Pharmacological therapies, vagal stimulation, and sympathetic ablation have shown efficacy in these diseases. Similar results can be obtained by biofeedback therapies.

2017 ◽  
Vol 14 (2) ◽  
pp. 1-4 ◽  
Author(s):  
Miqdhaadh Shareef ◽  
Man Bahadur KC ◽  
Roshan Raut ◽  
Anish Hirachan ◽  
Bishal KC ◽  
...  

Background and Aims: Heart failure is a major global health problem, but studies on prevalence of heart disease in Nepal are sparse. The aim of this study is to describe the etiology of heart failure patients in emergency department of Shahid Gangalal National Heart Centre.Methods: This was a single centre, prospective, observational study, conducted in the Emergency Department of National Heart Centre, from 1st May to 30th August 2016. All (n=591) consecutive patients with clinical diagnosis of heart failure were evaluated.Results: The mean age of the patients was 56.48 ±19.44 years, with 45.9% males. 31.3% had atrial fibrillation. The commonest cause of heart failure was rheumatic heart disease (25.1%), followed by dilated cardiomyopathy (22.8%), and coronary artery disease (18.1%). The commonest causes in the age group ≤44 years were rheumatic heart disease (61.9%), and congenital heart disease (11.0%). Commonest causes in the age groups 45 – 64 years and ≥ 65 years were dilated cardiomyopathy (29.0% and 26.4%, respectively) and coronary artery disease (22.3% and 24.3%, respectively). The commonest causes in male was dilated cardiomyopathy (26.9%) and in female it was rheumatic heart disease (31.6%).Conclusion: Rheumatic heart disease, dilated cardiomyopathy and coronary artery disease are the commonest cause of heart failure. Appropriate prevention strategies focused at these causes of heart failure are required to decrease the burden of heart failure in Nepal.Nepalese Heart Journal 2017; Vol 14(2), 1-4


2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
Y Hamatani ◽  
M Iguchi ◽  
K Minami ◽  
K Ishigami ◽  
S Ikeda ◽  
...  

Abstract Background Atrial fibrillation (AF) increases the risk of hospitalization for heart failure (HF), as well as that of thromboembolism. The strategy for prediction of thromboembolism has been well-established; however, little focus has been placed on the risk stratification for and prevention of HF hospitalization in AF patients. Purpose The aim of this study is to investigate the predictors and risk model of HF hospitalization in non-valvular AF patients without pre-existing HF. Methods The Fushimi AF Registry is a community-based prospective survey of AF patients in Fushimi-ku, Kyoto, Japan. The inclusion criterion of the registry is the documentation of AF at 12-lead electrocardiogram or Holter monitoring at any time, and there are no exclusion criteria. We started to enroll patients from March 2011, and follow-up data were available for 4,472 patients by the end of October 2020. From the registry, we excluded patients without a pre-existing HF (defined as having one of the following; prior hospitalization for HF, New York Heart Association class ≥2, or left ventricular ejection fraction [LVEF] <40%), and those with valvular AF (mitral stenosis or prosthetic heart valve). Among 3,188 non-valvular AF patients without pre-existing HF, we explored the risk factors for the HF hospitalization during follow-up period. The risk model for predicting HF hospitalization was determined by the cumulative numbers of risk factors which were significant on multivariate analysis. Results The mean age was 72.4±10.8 years, 1197 were female and 1787 were paroxysmal AF. The mean CHADS2 and CHA2DS2-VASc scores were 1.7±1.2 and 2.9±1.6, respectively. During the median follow-up period of 5.1 years, HF hospitalization occurred in 285 (8.9%), corresponding to an annual incidence of 1.8 events per 100 person-years. In multivariable Cox regression analysis, advanced age (≥75 years), valvular heart disease, coronary artery disease, reduced LVEF (<60%), chronic obstructive pulmonary disease (COPD) and anemia were independently associated with the higher incidence of HF hospitalization (all P<0.001) (Picture 1). A risk model based on these 6 variables could stratify the incidence of HF hospitalization during follow-up period (log-rank; P<0.001) (Picture 2). Patients with ≥3 risk factors had an 11-fold higher incidence of HF hospitalization compared with those not having any of these risk factors (hazard ratio: 11.3, 95% confidence interval: 7.0–18.4; P<0.001). Conclusions Advanced age, coronary artery disease, valvular heart disease, reduced LVEF, COPD and anemia were independently associated with the risk of HF hospitalization in AF patients without pre-existing HF. There was good prediction for endpoint of HF hospitalization using these 6 variables, providing the opportunities for the implementation of strategies to reduce the incidence of HF among AF patients. FUNDunding Acknowledgement Type of funding sources: None.


PPAR Research ◽  
2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Izabela Wojtkowska ◽  
Tomasz A. Bonda ◽  
Andrzej Tysarowski ◽  
Katarzyna Seliga ◽  
Janusz A. Siedlecki ◽  
...  

TNFα and PPARγ are important modulators of metabolism, inflammation, and atherosclerosis. Coronary artery disease is the leading cause of heart failure (HF). The aim of the study was to assess whether polymorphisms of the TNFα (-308G>A) and PPARG2 (Pro12Ala) genes are associated with the risk of developing HF by patients with ischemic heart disease. Methods. 122 patients without HF (aged 63 ± 8.8 years, 85% males) with confirmed coronary artery disease qualified for coronary bypass grafting were enrolled in the study. After the procedure, they were screened for cardiac parameters. Those with elevated NT-proBNP or diminished left ventricular ejection fraction during follow-up were assigned to the HF group (n=78), and the remaining ones to the non-HF group (n=44). The TNFα -308G>A and PPARG2 Pro12Ala polymorphisms were detected using the TaqMan method. Results. The distributions of TNFα -308G>A and PPARG2 Pro12Ala did not differ between the HF and non-HF groups (-308G>A: 16% vs. 11.4% of alleles; Pro12Ala: 23.9% vs. 20.5% of alleles, respectively). IL-6 concentration in the plasma of TNFα A-allele carriers at months 1 and 12 after CABG was higher in the HF group compared to the non-HF group (1 month after CABG: 5.3 ± 3.4 vs. 3.1 ± 2.9, p<0.05; 12 months after CABG: 4.2 ± 3,9 vs. 1.4 ± 1.2, p<0.01, respectively). Both polymorphisms were not related to changes in the plasma TNFα concentration or other parameters related to HF. Conclusions. Our study did not reveal any correlation between the PPARG2 Pro12Ala and TNFα -308G>A polymorphisms and development of HF in patients with ischemic heart disease after coronary bypass grafting.


2019 ◽  
Author(s):  
zhiying zhao ◽  
Jing Jin ◽  
Yong Sheng ◽  
Rong Yu ◽  
Biao Cheng

Abstract Background -The readmission reasons for senile patients hospitalized in different wards with acute decompensated heart failure are not well known. Method -We conducted a retrospective study of senile patients admitted to the People’s Hospital of Sichuan Province in a one-year period. Patients suffered with heart failure were identified from the hospital administrative database. Chart reviews were carried out to explore 30-day readmission reasons. Descriptive statistics were utilized to compare the patients and hospital characteristics among different wards. Student’s t-test was used for normally distributed continuous variables, chi-square for categorical variables. Results -Of all the hospitalization cases (3922), 1316 patients with heart failure were rehospitalized, among which 893 were admitted to geriatric department. The readmission rate was 33.55%. The top 10 reasons for rehospitalization in geriatric department were AECOPD (18.5%), hypertension (15.5%), hypertensive heart disease (13.3%),pneumonia (10.5%), coronary artery disease(7.0%), acute coronary syndrome(11.3%),
dementia (6.8%), PAD (3.25%), stroke (2.2%), cancer/valvular heart disease (1.4%).The top 10 reasons in other departments were stroke (32.5%), AECOPD (10.7%), pneumonia (10.0%), coronary artery disease(6.8%),CKD (5.9%), cancer(5.7%), hypertensive heart disease (4.8%), dementia (4.6%), valvular heart disease (3.3%), DCM (2.6%). Geriatric department tended to receive more senile patients than other wards, and had longer days of hospitalization(24.38±5.228 vs15.65±5.907), however, the cost among different wards was of no difference (31345.53±1343.354 vs 30868.49±2241.292). In terms of discharge disposition, 98.95% patients in geriatric department were discharged straight to home, ‘which was statistically higher than that of other wards (86.68%). Conclusion -This study shows the prevailing reasons for readmission of senile patients hospitalized with acute decompensated heart failure. Long term or short term care is summoned in China.


2021 ◽  
Author(s):  
Saraí López De Lucio ◽  
Marco Antonio López Hernández

All over the world ischemic heart disease remains as the leading cause of death, followed by stroke. Ischemic heart disease, also called coronary artery disease has a broad spectrum of clinical manifestations from the acute coronary syndromes which include, unstable angina pectoris and acute myocardial infarction with and without elevation of the ST segment and chronic coronary disease. In patients with diabetes mellitus the cardiovascular complications mainly ischemic heart disease, are the main cause of morbidity and mortality. However, in population-based studies, the risk of heart failure in patients with diabetes mellitus is significantly increased following adjustment for well-established heart failure risk factors such as hypertension or ischemic heart disease. Ischemic heart failure angiographically diagnosed is associated with a shorter survival than non-ischemic heart failure. Coronary artery disease is independently associated with higher mortality.


2018 ◽  
Vol 25 (13) ◽  
pp. 1510-1524 ◽  
Author(s):  
Roberto Tarquini ◽  
Laura Pala ◽  
Simona Brancati ◽  
Giulia Vannini ◽  
Salvatore De Cosmo ◽  
...  

Background: Diabetic Cardiomyopathy (DC) has been defined as a distinct entity characterized by the presence of diastolic or systolic cardiac dysfunction in a diabetic patient in the absence of other causes for Cardiomyopathy, such as coronary artery disease (CAD), hypertension (HTN), or valvular heart disease. Diabetes affects every organ in the body and cardiovascular disease accounts for two-thirds of the mortality in the diabetic population. Diabetes-related heart disease occurs in the form of coronary artery disease (CAD), cardiac autonomic neuropathy or DC. The prevalence of cardiac failure is high in the diabetic population and DC is a common, but underestimated cause of heart failure in diabetes. The strong association between diabetes and heart failure has fueled intense human and animal research aimed at identifying the mechanisms underlying diabetic myocardial disease. Despite significant progress made, the precise pathogenesis of diabetic Cardiomyopathy is yet to be clearly defined. Hyperglycemia, dyslipidemia and inflammation are thought to play key roles in the generation of reactive oxygen or nitrogen species which are in turn involved. Methods: We have reviewed the up-to-date scientific literature addressing these issues. Results: The myocardial interstitium undergoes alterations resulting in abnormal contractile function noted in DC. In the early stages of the disease, diastolic dysfunction is the only abnormality, but systolic dysfunction supervenes in the later stages with impaired left ventricular ejection fraction. Transmitral Doppler echocardiography is usually used to assess diastolic dysfunction, but tissue Doppler Imaging and Cardiac Magnetic Resonance Imaging are being increasingly used for early detection of DC. Diabetic patients with microvascular complications show the strongest association between diabetes and Cardiomyopathy, an association that parallels the duration and severity of hyperglycemia. Conclusion: The management of DC involves improvement in lifestyle, control of glucose and lipid abnormalities, together with treatment of hypertension and CAD, if present.


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