The Effect of an Artificial Tear Combining Hyaluronic Acid and Tamarind Seeds Polysaccharide in Patients with Moderate Dry Eye Syndrome: A New Treatment for Dry Eye

2014 ◽  
Vol 24 (2) ◽  
pp. 173-178 ◽  
Author(s):  
Stefano Barabino ◽  
Maurizio Rolando ◽  
Marco Nardi ◽  
Stefano Bonini ◽  
Pasquale Aragona ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Dry Eye ◽  
Dry Eye Syndrome ◽  
Artificial Tear ◽  
New Treatment

New preparations of hyaluronic acid in the treatment of patients with dry eye syndrome of various origins

2020 ◽  
pp. 180-181
Author(s):  
V.V. Brzheskiy ◽  
◽  
S.Y. Golubev ◽  
I.V. Brzheskaya ◽  
V.Y. Popov ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Dry Eye ◽  
Dry Eye Syndrome

scholarly journals A Meta-Analysis of the Efficacy of Hyaluronic Acid Eye Drops for the Treatment of Dry Eye Syndrome

2021 ◽  
Vol 18 (5) ◽  
pp. 2383
Author(s):  
Yun-Jung Yang ◽  
Won-Young Lee ◽  
Young-jin Kim ◽  
Yeon-pyo Hong
Keyword(s):  
Hyaluronic Acid ◽  
Confidence Interval ◽  
Dry Eye ◽  
Test Scores ◽  
Meta Analysis ◽  
Mean Difference ◽  
Dry Eye Syndrome ◽  
Eye Drops ◽  
Cochrane Central Register ◽  
Standard Mean Difference

Hyaluronic acid (HA) is commonly used for treating dry eye syndrome (DES). This meta-analysis was performed to compare the efficacies of HA- and non-HA-based eye drops, including saline and conventional artificial tears (ATs), for the treatment of dry eye disease. Eight databases (PubMed, EMBASE, Cochrane Central Register of Controlled Trials, DBpia, KoreaMed, KMBASE, RISS, KISS) were searched for studies comparing the efficacies of HA- and non-HA-based ATs in patients with DES published up to September 2020. Two independent reviewers assessed the quality and extracted the relevant data. The mean differences of Schirmer’s (SH) test scores, tear breakup times (TBUT), corneal fluorescein staining scores (Oxford scale, 0–4), and ocular surface disease indexes were calculated. The standard mean difference and 95% confidence interval were calculated using a random effect model. Nineteen studies, including 2078 cases, were included. HA eye drops significantly improved tear production compared with non-HA-based eye drops (standard mean difference (SMD) 0.18; 95% confidence interval (CI) 0.03, 0.33). In a subgroup analysis, the SH test scores and TBUT values after using HA significantly increased compared to those measured after using saline (SMD 0.27; 95% CI 0.05, 0.49 and SMD 0.28; 95% CI 0.03, 0.52, respectively). Based on these results, HA eye drops may be superior to non-HA eye drops including normal saline and ATs. Further research is needed to assess the efficacies stratified by age, treatment duration, the severity of dry eye, and optimal dosages.

scholarly journals Crosslinked hyaluronic acid with liposomes and crocin for management symptoms of dry eye disease caused by moderate meibomian gland dysfunction

2019 ◽  
Author(s):  
José-María Sánchez-González ◽  
Concepción De-Hita-Cantalejo ◽  
María Carmen Sánchez-González
Keyword(s):  
Hyaluronic Acid ◽  
Dry Eye ◽  
Meibomian Gland ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Schirmer Test ◽  
Ocular Surface Disease Index ◽  
Artificial Tear ◽  
Before And After ◽  
Contralateral Eye

Abstract Background: To study the effect of uncrosslinked and crosslinked hyaluronic acid combined with other artificial tear components in patients with dry eye caused by moderate meibomian gland dysfunction.Method: Prospective, single-blind, contralateral eye study. Fifty eyes were analyzed (25 patients). Eye selection for each tear type was random, and the eye drop formulations Aquoral Forte® (artificial tear A) and Aquoral Lipo® (artificial tear B) were used. The determined dosing schedule was three times a day for six weeks, and the study participants underwent a clinical examination before and 45 days after lubricant treatment. The Schirmer test, tear breakup time (TBUT) test, and Ocular Surface Disease Index (OSDI) questionnaire were applied before and after instillation period with both types of artificial tears. Results: On the Schirmer test, a significant improvement was obtained with both tear A (p < 0.01) and tear B (p < 0.01). On the TBUT test, a significant improvement was obtained with tear A (p < 0.01) and tear B (p < 0.01). The OSDI score significantly decreased after instillation period with both artificial tear types (p < 0.01). Conclusion: Uncrosslinked hyaluronic acid combined with other components, such as tamarind seed polysaccharide, and crosslinked hyaluronic acid combined with liposomes and crocin are effective for management symptoms of dry eye disease.

scholarly journals Use of preservative-free hyaluronic acid (Hylabak®) for a range of patients with dry eye syndrome: experience in Russia

2014 ◽  
pp. 1169 ◽  
Author(s):  
John Stolz ◽  
Vladimir Brjesky ◽  
Yury Maychuk ◽  
Alexey Petrayevsky ◽  
Peter Nagorsky
Keyword(s):  
Hyaluronic Acid ◽  
Dry Eye ◽  
Dry Eye Syndrome ◽  
Preservative Free

Features of the Clinical Course and Treatment of Dry Eye Syndrome in the Setting of Chronic Conjunctivitis in the South Aral Sea Region

The Eye ◽  
2021 ◽  
Vol 23 (3) ◽  
pp. 39-45
Author(s):  
F. A. Bakhritdinova ◽  
A. K. Matkarimov ◽  
S. Sh. Mirrakhimova ◽  
Z. R. Maksudova
Keyword(s):  
Dry Eye ◽  
Main Group ◽  
Dry Eye Syndrome ◽  
Aral Sea ◽  
Control Group ◽  
Eye Drops ◽  
Long Term Effects ◽  
The South ◽  
Artificial Tear ◽  
Chronic Conjunctivitis

Background. Currently, the health status of the population in the Aral Sea region should be considered with reference to long-term effects of environmental pollution – air, soil and drinking water containing toxic salts. As per results of the analysis of primary eye diseases in the Southern Aral Sea region, it was revealed that the main cause of conjunctivitis were chemical and physical exogenous irritation factors, such as dust, smoke and exposure to salt and sand storms that create a favorable environment for infection and development of secondary Dry Eye Syndrome. Purpose. To optimize treatment of secondary Dry Eye Syndrome (DES) in patients with chronic conjunctivitis in the South Aral Sea region. Materials and Methods. The research included 62 patients (120 eyes) with chronic conjunctivitis, aged 35–62 years, who had been observed in an outpatient clinic for the last 3 years, with signs of DES. All studied patients were divided into 2 groups by random sampling after preliminary adequate antibacterial and anti-inflammatory therapy. The control group (20 patients, 40 eyes) was instilled with Tsinosol antiseptic (composition: zinc sulphate, boric acid, Aseptic) – 2 drops 3 times a day, during 30 days. Patients of the main group (42 patients, 80 eyes) were instilled with Tsinosol antiseptic (2 drops 3 times a day) and Keratrop artificial tear (AT) eye drops (composition: sodium carmellose, glycerin, levocarnitine, erythrol, firma Aseptica) – 2 drops 3 times a day, during a month. All patients underwent standard ophthalmological tests, and special tests were carried out to verify DES, including Schirmer, Norn and Jones tests. Lower lacrimal meniscus height and the severity of the conjunctival fold were also determined. Results. Studies have shown that in the main group, both subjective and objective signs of the disease significantly decreased compared with the baseline and with the respective parameters of the control group, and a significant improvement in the stability of the tear film was noted. Conclusion. To optimize the therapy of secondary DES, it is necessary to include artificial tear eye drops in the treatment regimen in general, and consider using Keratrop eye drops in particular.

Artificial tear drops Thealoz in the correction of dry eye syndrome after keratorefractive surgery

2019 ◽  
Vol 135 (2) ◽  
pp. 113 ◽  
Author(s):  
I. E. Panova ◽  
A. V. Titov ◽  
S. P. Golovatenko ◽  
D. R. Mirsaitova ◽  
O. P. Leshchik ◽  
...  
Keyword(s):  
Dry Eye ◽  
Dry Eye Syndrome ◽  
Artificial Tear ◽  
Keratorefractive Surgery

Сomparative effect of artificial tear drug usage in patients with «dry eye» syndrome and chronic blepharitis

2013 ◽  
Vol 4 (1) ◽  
pp. 53-57 ◽  
Author(s):  
Lyudmila Petrovna Prozornaya ◽  
Vladimir Vsevolodovich Brzheskiy
Keyword(s):  
Present Article ◽  
Dry Eye ◽  
Dry Eye Syndrome ◽  
Treatment Results ◽  
Drug Usage ◽  
Artificial Tear ◽  
Chronic Blepharitis

During recent years, the problem of treatment «dry eye» syndrome in patients with chronic blepharitis is very important. But until there are no rational standards how to treat such patients. We investigated group of 44 adults with the chronic blepharitisand concomitant dry eye syndrome. In present article, рresented are the treatment results of artificial tear drug usage in patient with «dry eye» syndrome and chronic blepharitis.

Sign in / Sign up

Export Citation Format

Share Document