Normal Reference Values of Complete Blood Count in Healthy Adult Population of Pakistan; A Multicentre Study

2021 ◽  
Vol 15 (11) ◽  
pp. 3040-3042
Author(s):  
Neelam Mazhar ◽  
Sarah Rafi ◽  
Saima Farhan ◽  
Shazia Yaseen ◽  
Nisar Ahmed
Keyword(s):  
Reference Values ◽  
Blood Count ◽  
Blood Donors ◽  
Complete Blood Count ◽  
Hematological Parameters ◽  
Adult Population ◽  
Armed Forces ◽  
Reference Ranges ◽  
Medical College ◽  
Normal Reference

Aim: To establish the reference values of hematological parameters in blood donors of all the four provinces of Pakistan as a general population. Methods: This was a multicenter cross-sectional study conducted from Jan 2017-Oct 2017 in the blood bank and the Dept. of Haematology, The CH&ICH, Lahore, Fatimid Foundation, Karachi, Bolan medical college, Quetta, Armed Forces Institute of Transfusion, Rawalpindi & Ayub medical college, Abbottabad, KPK. Blood samples of 1060 male and female blood donors were collected from the blood banks of all the centers mentioned above. CBC and differential were performed using an automated hematology analyzer in the respective departments. Results: The mean and 95% reference values (2.5th-97.5th) for males WBC 7.752+4.506×109 cells/L, RBC 4.958 +1.331, HB 14.258 +3.423 g/dl, HCT 41.967 +16.345, MCV 84.584 +15.933, PLT 219.485 +197.331, LYM 3.346 +10.112, NEUT 6.843+23.557, MONO 0.811 +3.601, EO 0.327 +0.995. For females WBC 7.174+3.037, RBC4.567 +1.086, HB 12.972 +2.752, HCT39.647 +48.186, PLT 264.07+175.079, LYM 2.537+5.005, NEUT 4.769+11.314, MONO 0.460 +0.909, EO 0.188+0.39 Conclusion: The hematological profile of the population in all four provinces of Pakistan differed from the reports of other countries and the standard reference ranges described in the textbook. So, our own hematological parameters must be followed. More studies must be carried out on other age groups and even on adults to strengthen our results. Keywords: Normal reference values, Complete blood count, Healthy adults of Pakistan

Tunisian Newborn's Cord Blood: Reference Values of Complete Blood Count and Hemoglobin Fractions

2020 ◽  
Author(s):  
Sana Zitouni ◽  
Emna Bouatrous ◽  
Ons Laabidi ◽  
Imen Boudrigua ◽  
Dorra Chaouachi ◽  
...  
Keyword(s):  
Blood Cell ◽  
Cord Blood ◽  
Reference Values ◽  
Blood Count ◽  
Complete Blood Count ◽  
Hematological Parameters ◽  
Reference Ranges ◽  
Hematological Indices ◽  
Umbilical Blood ◽  
Vaginal Deliveries

Objective This study was aimed to establish local reference values for hematological indices and hemoglobin (Hb) fractions in umbilical cord blood (UCB) for the northern population of Tunisia. Study Design Our study included full-term newborns by vaginal deliveries. Hematological parameters were collected using an automated blood cell counter. The amounts of Hb fractions were measured by capillary electrophoresis of Hb. Statistical analysis was performed using R software. Results A total of 328 cord blood samples were analyzed. Among them, 154 (male: 44.8%, female: 55.2%) were used to establish reference values. The normal reference values of complete blood count (CBC) and Hb fractions were calculated. Mean neonatal Hb was 14.75 ± 2.26 g/dL. Gestational age affects the expression of CBC values as red blood cell (RBC), Hb, hematocrit (Hct), mean corpuscular volume (MCV), white blood cell (WBC), and the Hb profile. Umbilical blood hemogram parameters and Hb profile are affected by the environment; higher in newborns from urban regions but not affected by gender ratio. Conclusion Reference ranges of normal CBC indices and Hb fractions have been successfully established in Tunisian neonates' UCB. Our data suggest reference values that could be useful for neonatal patients' laboratory results and clinical interpretation. Key Points

scholarly journals Hematological parameters of the blood count in a healthy population of pregnant women in the Northwest of Morocco (Tetouan-M'diq-Fnideq provinces)

2018 ◽  
Vol 29 ◽  
Author(s):  
Saad Bakrim ◽  
Youssef Motiaa ◽  
Ali Ouarour ◽  
Azlarab Masrar
Keyword(s):  
Pregnant Women ◽  
Reference Values ◽  
Blood Count ◽  
Complete Blood Count ◽  
Hematological Parameters ◽  
Control Group ◽  
Mean Corpuscular Hemoglobin ◽  
Healthy Population ◽  
Corpuscular Hemoglobin ◽  
Significant Difference

Introduction: numerous biological parameters are physiologically modified during normal pregnancy, in particular hematology. The knowledge of these modifications of the maternal body by biologists and clinicians allows the screening of possible anomalies. In Morocco, the reference values of the complete blood count test for pregnant woman are missing, as are those specific to different trimesters of pregnancy. The aim of this study is to look for the reference values for healthy pregnant women of the Northwest region of Morocco, to compare them to those of non-pregnant women (control) and to those of the literature. Methods: blood samples were taken voluntarily from 3898 healthy pregnant women from 18 to 46 years old who presented themselves at the center of health Kalaa and at the service of gynecology obstetrics of the Provincial Hospital Center of M'diq (Morocco), for prenatal care. To establish the reference intervals of the CBC for non-pregnant women, a control group was constituted by 7035 healthy women from 18 to 50 years old selected according to the Moroccan law of blood donation. The CBC was measured on a Sysmex KX21N® analyzer. For each sample a systematic blood smear was done to determine the leukocyte differential. Results: a statistically significant difference between the pregnant women and control group was noted (p < 0.05) for all the hematological parameters: red blood cells, hematocrit, hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, leukocytes, neutrophils, basophils, eosinophils, lymphocytes, monocytes, platelets and mean platelet volume. So, the comparison of the averages established between the first, second and third trimester of pregnancy showed the existence of a significant variation with regard to all the parameters of the CBC test looked for (p < 0.001). Conclusion: the present study provides additional baseline data for basic hematological parameters in healthy pregnant Moroccan women and concluded that pregnancy in women has the tendency to alter some hematological indices. For these reasons, there is an interest to take these modifications into account for optimal maternal and fetal medical care.

scholarly journals ROLE OF HEMATOLOGICAL PARAMETERS IN COVID-19 PATIENT IN INDEX MEDICAL COLLEGE, INDORE

2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Deeksha Gupta ◽  
Sanjeev Narang
Keyword(s):  
Blood Count ◽  
Complete Blood Count ◽  
Hematological Parameters ◽  
Clinical Status ◽  
Supportive Treatment ◽  
Female Population ◽  
Medical College ◽  
Persistent Symptoms ◽  
A Prospective Study

AIM: Study to evulate the pattern of the hematolofical parameters of covid-19 patients along with their clinical course in the Indian scenario. Material& method: A prospective study of 100 patients with laboratory-confirmed covid-19 admitted to index medical college indore from April to june were enrolled for the study. Patients were divided into asymptomatic (mild) patients, and symptomatic (moderate). The demographic date, the clinical status of the patients during admission, and follow up and hematological finding were recorded. The semples for complete blood count and peripheral smears for microscopy examination were collected on the day of admission .the sample were tested for complete blood count on 5-part hematology analyzer, and values were recorded. peripheral smears were stained by gimsa stains, and findings were noted. Results: All the paediatric cases under study were stable and asymptomatic, with only supportive treatment. Adults patients included in the study were given supportive treatment, and only one case showed clinical deteriotion over a period of 90 day of admission. Conclusion: The study of 100 covid-19 cases of Indian population shows that majority of the patients are younger, have asymptomatic to mild clinical presentation, and a higher incidence in the female population. The majority of pediatric cases have mild symptomology with a stable clinical corse. Baseline CBC finding of all the cases show. mild neutrophilia, mild lymphopenia, eosinophilia, mild monocytosis, and a normal to mild thromobocytopenia. a significance statistical trend of increase in CBC PARAMETER, NLR, was noted in follow up cases with persistent symptoms, however, a larger follow up cohort is needed to arrive at a statistical significances. Keywords: hematological, covid-19 & neutrophilia.

Variation in blood count parameters of children aged 5 to 11 years in Abidjan, Côte d'Ivoire

2021 ◽  
Author(s):  
Kokore Angoua Baudouin ◽  
Kamagate Soualio ◽  
Ouattara Howélé ◽  
Bleyere Nahounou Mathieu ◽  
Yapo Paul
Keyword(s):  
Reference Values ◽  
Cote D'ivoire ◽  
Mean Corpuscular Volume ◽  
Blood Count ◽  
Côte D’Ivoire ◽  
Hematological Parameters ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Hemoglobin ◽  
Cote D’Ivoire ◽  
Côte D'ivoire

Background: In Côte d’Ivoire, as in most developing countries, the reference values of hematological indices currently in use come from data collected from populations living in industrialized countries. The aim of this study was to determine variations in the child's blood count in Cote d'Ivoire. Materials and Methods: This descriptive cross-sectional study has focused on 310 children (172 girls and 138 boys) aged 5 to 11 years selected from three municipalities of Abidjan. Blood samples were taken from each child in order to assess the parameters of the blood count. Results: The results revealed that the means of the different hematological parameters (red blood cells, hemoglobin, hematocrit, white blood cells, neutrophils, eosinophils, monocyte, mean corpuscular volume, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration) were in accordance with the normal physiological reference values from the literature apart lymphocyte. The rate of lymphocytes (51.3 ± 0.5) was higher overall. All the parameters did not indicate significant differences between girls and boys (p > 0.05) except mean corpuscular volume, and mean corpuscular hemoglobin that were statistically different by sex (p < 0.05). The percentage of having a rate of haemoglobin lower than 11.5 decreased significantly (p˂0.005) when the age increased. In addition, the rate of hemoglobin and hematocrit increased slightly starting from the age of 8 years. There is a significant difference (p < 0.05) in hemoglobin level between girls and boys in the age group of 9 years. Leukopenia is observed in a minority of children in the age groups of 5, 6, 7, 8, and 10 years. Conclusion: Some hematological parameters were different from other data published in the literature, which suggested a local development of reference values for children.

scholarly journals Ancestry informative markers and complete blood count parameters in Brazilian blood donors

2010 ◽  
Vol 32 (4) ◽  
pp. 282-285 ◽  
Author(s):  
Gabriela E. S. Felix ◽  
Kiyoko Abe-Sandes ◽  
Taísa M. Bonfim ◽  
Maria T. Bendicho ◽  
Patrícia Cisneiros ◽  
...  
Keyword(s):  
Blood Count ◽  
Blood Donors ◽  
Complete Blood Count ◽  
Ancestry Informative Markers

Full blood count normal reference values for adults in France

2013 ◽  
Vol 67 (4) ◽  
pp. 341-344 ◽  
Author(s):  
Xavier Troussard ◽  
Sylviane Vol ◽  
Edouard Cornet ◽  
Valérie Bardet ◽  
Jean-Paul Couaillac ◽  
...  
Keyword(s):  
Reference Values ◽  
Blood Count ◽  
Full Blood Count ◽  
Normal Reference

Fetal echocardiography: reference values for the Chinese population

2017 ◽  
Vol 45 (2) ◽  
Author(s):  
Xiaoyan Gu ◽  
Yihua He ◽  
Ye Zhang ◽  
Lin Sun ◽  
Ying Zhao ◽  
...  
Keyword(s):  
Reference Values ◽  
Fetal Echocardiography ◽  
Ductus Arteriosus ◽  
Cross Sectional Study ◽  
Quadratic Model ◽  
Reference Ranges ◽  
Single Center ◽  
Cross Sectional ◽  
Normal Reference ◽  
Inner Diameter

AbstractObjective:Global racial variability in human development can lead to differences in size of fetal cardiac structures during gestation. Our objective is to establish normal reference ranges of fetal cardiac dimensions between 20 and 34 weeks from fetal echocardiograms recorded at a single center in China.Methods:A prospective cross-sectional study was undertaken on single pregnancies with normal fetuses of varying gestational ages (GAs). A total of 4396 normal fetuses were divided into 15 groups from 20 to 34 weeks according to the GA. Measurements included the inner diameter of the fetal cardiac chambers and arteries, the aortic arch isthmus (AI), the descending aorta (DAO), the ductus arteriosus (DA), and the foramen ovale (FO). Measurements were statistically analyzed and regression analysis was applied to assess for correlation with GA.Results:Normal reference values of fetal cardiovascular dimensions between 20 and 34 weeks were obtained from 4396 subjects at a single center in China. Measurements of fetal cardiac structures increase with advancing GA. It seems there is no difference in r values among linear, cubic, and quadratic model analyses (P > 0.05). However, the r values for the exponential models appear to be smaller than those of the other three models (P < 0.05). Ratios of the diameters of fetal cardiac structures were calculated in order to identify for differential changes in the growth of structures.Conclusions:The presented data derived from 4396 normal fetuses provide the reference values of fetal echocardiography in China, which provide guidance to fetal echocardiography examinations.

scholarly journals NILAI RUJUKAN HEMATOLOGI PADA ORANG DEWASA SEHAT BERDASARKAN SYSMEX XT-1800i

2018 ◽  
Vol 12 (3) ◽  
pp. 137
Author(s):  
T Esa ◽  
S Aprianti ◽  
M Arif ◽  
Hardjoeno .
Keyword(s):  
Reference Values ◽  
Laboratory Tests ◽  
Blood Count ◽  
Healthy Adult ◽  
Blood Donation ◽  
Complete Blood Count ◽  
Reference Value

The reference values of laboratory tests are affected by factors such as instruments and methods of tests, which are always beingdeveloped. For these reasons, each laboratory is recommended to determine their own reference values. To determine the reference valuesof complete blood count in healthy adult people, and compare them to the reference values which is taken from the references. A crosssectional study was conducted on 200 healthy adult people, aged 18-60 years, selected during blood donation. The eight haematologicalparameters were estimated using Sysmex Xt-1800i at Dr.Wahidin Sudirohusodo Hospital. The data were analyzed statistically by SPSS11.5 programs. The reference values of leukocyte, erythrocyte, haemoglobin, hematocrit, MCV, MCH, MCHC and platelet were: 4400 to10000 /µL; %:4.2–6.2 × 106/µL; &:3.8–5.5 × 106/µL; %:12.5–17.3 g/dL; &:11.8–15.4 g/dL; %:38.1–50.4 %; &:31.1–49.7 %; 80,1to 94,3 fL, 25,9–31,9 pg, 31,4–35,2 g/dL, and %:171.2–405.1 × 103/µL; &:191.8–441.5 × 103/µL, respectively. Significant differenceswere observed in the MCH and platelet values (p< 0,005). The values found in this study were similar to the reference value commonlyused in our laboratory, except for the MCH value which was lower and the platelet value which was higher..

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