Prevalence of Anemia and Use of Iron Supplements in MBBS Students of CMH Lahore Medical College

2021 ◽  
Vol 15 (6) ◽  
pp. 1185-1187
Author(s):  
S. Zaffar ◽  
Q. U. Khan ◽  
H. Tanveer ◽  
I. R. Chattha ◽  
N. Rashid ◽  
...  

Background: Iron deficiency anemia afflicts masses of all ages, worldwide. The disease tends to be prominent in the adolescence, students being more vulnerable due to their dynamic lifestyle, dietary habits and demanding growth spurt. Use of iron supplements can greatly reduce the burden of disease and associated morbidity. The objective of this study was to estimate the prevalence of anemia and use of iron supplements in MBBS students of CMH Medical College, Lahore. Methods: A cross sectional study was conducted in CMH Medical College, Lahore. A predesigned questionnaire was used to obtain information regarding use of iron supplements. Afterwards, hemoglobin level was measured using conventional Sahli’s method. The collected data was analyzed with SPSS 25 software. Results with p value < 0.05 were taken as significant. Results: Mean hemoglobin level was found to be 14.3±1.3 g/dL in males and 11.6±1.4 g/dL in females. Prevalence of anemia was found to be 38.7%. Anemia was found to be more prevalent in female students (57.8%) as compared to the male students (14.9%). Difference between prevalence of anemia in hostellites and day scholars was not found to be statistically significant (p = 0.17). Frequency of anemia was observed to be significantly higher in students who did not use oral iron supplements (p=0.03). Conclusion: Iron deficiency anemia is more common in female students than male students, of CMH Medical College Lahore. Majority of the anemic students do not take oral iron supplements. There is no difference in the prevalence of anemia among hostellites and day scholars. MeSH words: anemia, hemoglobin, iron supplements

Author(s):  
Satish Kumar

Introduction: Anemia is the commonest major contributing factor in maternal mortality and morbidity in developing countries and according to World Health Organization (WHO) criteria, it contributes to 20% of maternal deaths. Anemia in pregnancy defined as hemoglobin level <11 gm/dl (7.45 mmol/L) and hematocrit less than 33% (WHO). Aim: To compare the efficacy of oral iron ferrous sulphate therapy with intravenous iron sucrose therapy in the treatment of iron deficiency anemia during postpartum period. Material & Methods: This was a prospective randomized comparative clinical trial single center study conducted on 200 postpartum women aged >18 years (after normal delivery or LSCS) within 10 days of delivery with Hb level more or equal to 6 gm/dl but less than 10 gm/dl were included in the study. This was a one year study conducted during 1st December 2018 to 30th November 2019. Results : There was a significant increase in the hemoglobin level in both the groups i.e. in IV iron group, from 8.26 ±1.03gm/dl on day 1 to 11.62±0.94gm/dl on day 45 as compared to oral iron group, from 8.24±1.09gm/dl on day 1 to 11.07±1.14gm/dl on day 45; and serum ferritin level from 41.69±40.45ng/ml on day 1 to 77.34±41.60ng/ml on day 45 in IV iron group as compared to the oral iron group from 22.20±8.82ng/ml on day 1 to 31.72±9.72 ng/ml on day 45. So, there was a rapid increase in both hemoglobin and serum ferritin levels in IV iron group as compared to the oral iron group. Conclusion: Intravenous iron sucrose administration increases the hemoglobin level and serum ferritin more rapidly in compare to the oral intake of ferrous sulphate in women with iron deficiency anemia in postpartum women in our study. Keywords: Iron deficiency anemia, Intravenous iron sucrose, Serum ferritin, Maternal mortality.


Blood ◽  
2010 ◽  
Vol 116 (21) ◽  
pp. 4229-4229
Author(s):  
Goldy Bansal ◽  
Jack Burton ◽  
Nay yee Win ◽  
Saman Selahi ◽  
Scott Foss

Abstract Abstract 4229 Introduction: Patients with iron deficiency anemia (IDA) who need intravenous iron are normally treated with iron dextran. One of the major side effects of iron dextran is severe (sometimes fatal) anaphylactic reaction, which can develop in about 1% of patients. On the other hand, iron sucrose (Venofer®) another intravenous iron preparation that has improved safety and ease of administration. This preparation is being used in dialysis patients with very good results. But this has never been formally evaluated in non-dialysis-dependent patients. In view of these issues with iron dextran, some non-dialysis dependent patients in the Hematology/Oncology clinic at Coney Island hospital with IDA who needed parental iron therapy for IDA (due to intolerance or poor response to oral iron) were offered treatment with Venofer®. Our study is done to assess the response of intravenous iron therapy Venofer® in non-dialysis dependent patients with IDA. Methods: Consecutive patients who were treated with Venofer® for IDA in the Hematology/Oncology clinic in Coney Island Hospital, Brooklyn, New York, USA were obtained medical records. The number of cases included in the study was 42. Charts of these patients were reviewed and key data were collected before the start of treatment and weekly after starting the treatment. Response was defined as an increase in the hemoglobin level of 2 g/dl or greater after starting the treatment. At the same time, the reason for starting the IV iron therapy and the toxicity associated with treatment was evaluated. The paired t test was used to assess hemoglobin response. Results: Patients received 200 mg by of Venofer® by slow IV push every week. Analysis showed that 35 out of 42 patients (83.3%) received 4 doses. The mean increase in hemoglobin level after 4 doses was 1.65±0.98 g/dl (P=0.00002). 7 out of 35 patients achieved increase of 2 g/dl or greater in hemoglobin level (response rate of 20%). 13 out of 42 patients (30.9%) continued to receive Venofer® up to 8 doses. The mean increase in hemoglobin level after 8 doses of treatment was 2.66±1.73 g/dl (P=0.00001). 11 out of 13 patients who received 8 doses achieved a hemoglobin increase of 2 g/dl or greater (response rate of 84.6%). Indications for starting IV iron for 12 patients was intolerance to oral iron due to GI side effects, for 24 patients it was no response with oral therapy, for 3 patients it was general malabsorption and other 3 patients due to non-compliance. Among all the patients studied, none had any complications related to intravenous iron. Background: Our data showed that intravenous the iron prepration, Venofer®, which is currently not the standard of care for treatment of IDA in non-dialysis-dependent patients has very good response (response rate of 20% after 4 cycles and 84.6 % after 8 cycles). It is well tolerated and has no major side effects. More studies needs to be done with larger number of patients, with attention to both medical and economic impact, before this can become a stanadard of care for non-dialysis-dependent patients with IDA, who do not respond or have intolerance to oral iron preprations. Disclosures: Off Label Use: Venofer® for iron deficiency anemia in non-dialysis dependent patients.


2019 ◽  
Vol 2 (2) ◽  
pp. 51
Author(s):  
Umriaty Umriaty ◽  
Tias Dwi Arti

Iron deficiency anemia is the most common type of Anemia in Indonesia . The iron needs of adolescent girls aged 13-29 years are much higher than boys of the same age. Women iron intake is not only used to support growth, but is also used to replace the iron that is lost through the blood when menstruation every month. Therefore women are at risk for anemia. Anemia in adolescents will have a long impact on himself and the baby who will be born later. This activity is an effort to reduce the incidence of anemia in adolescents. In addition to knowing hemoglobin levels, this activity was also given information about anemia in adolescents and the consumption of iron supplements. The results of examination of hemoglobin levels in 16 female students (11.2%) out of a total of 142 female students were detected as having anemia. The results of this activity also showed an increase in the average hemoglobin level for these students from 10, 9 gr / dl to 11.7 gr / dl. In addition, the results of the examination after the intervention also showed that 8 female students who had anemia at the beginning then within one month had normal Hemoglobin levels (> 12 gr / dl).Keyword: adolescent anemia, early detection, iron supplementation


2020 ◽  
Vol 27 (2) ◽  
pp. 175-181
Author(s):  
Dilshad Jahan ◽  
Mohammad Manirul Islam ◽  
Mohammad Zaid Hossain ◽  
Masuma Ahmed Salsabil ◽  
Iftadul Islam ◽  
...  

Background: Iron deficiency anemia (IDA) is one of the most frequent nutritional deficiency leading to morbidity and mortality in whole world. Oral iron therapy as well as intravenous (IV) iron therapy can be given to treat the IDA patients. Objective: To compare the efficacy and hematological changes of Oral and IV iron preparation in patients with uncomplicated iron deficiency anemia. Method: An interventional, prospective study in patients with uncomplicated IDA anemia receiving IV iron sucrose and Oral iron ferrous sulfate were included. Clinical history, baseline hemoglobin, anemia indices data were recorded in a case record form. A total number of 80 patients were enrolled in this study. 40 patients (Group A) were treated with IV iron sucrose and another 40 patients (Group B) were treated with oral iron ferrous sulfate. After therapy Hemoglobin level, RBC indices and adverse drug reactions (ADRs) were observed. Place and period of Study: Study was carried out in the Department of Hematology at Dhaka Medical College Hospital (DMCH), from July 2015 to June 2016. Results: The mean age of total participants was 35.77 ± 16.08 (range of 13 – 75 years). In this study female (72.5%) is predominant than male (27.5%). Oral and IV iron preparations significantly (P<0.0001) improved mean hemoglobin, anemia indices at the end of study. However, mean increase in hemoglobin were significant (P<0.0001) with IV iron sucrose (7.6 ± 2.9) gm/dl, as compared to Oral ferrous sulfate (6.4± 2.2)gm/dl, after 2 months of therapy. In this study Hemoglobin increases in group A (IV iron arm) almost 1mg/kg/week and in group B (oral iron arm) 0.8 mg/dl/week).Surprisingly, ADRs were more in patients treated with oral ferrous sulfate (38%) compared to iron sucrose (26%). Conclusion: IV iron sucrose improves hemoglobin, anemia indices and replenish iron stores rapidly and is well tolerated than oral iron preparations. J Dhaka Medical College, Vol. 27, No.2, October, 2018, Page 175-181


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ali Khani Jeihooni ◽  
Sanaz Hoshyar ◽  
Pooyan Afzali Harsini ◽  
Tayebeh Rakhshani

Abstract Background Iron deficiency anemia disrupts the concentration of adolescent girls; reduces their academic achievement, productivity, and physical strength, and increases the risk of infection. This research aim was to evaluate the effectiveness of the PRECEDE model nutrition education on iron deficiency anemia among female students of Fasa City, Fars Province, Iran. Methods This quasi-experimental study was done on 160 students (80 experimental and 80 control groups) who were selected using a random sampling method in Fasa City, Fars Province, Iran, in 2018–2019. The educational intervention included six sessions based PRECEDE model for 45 or 50 min. A scale of this study consisted of two parts; demographic information, and PRECEDE constructs were used to determine the nutritional behaviors status concluding preventing iron deficiency anemia and hemoglobin, hematocrit, and ferritin blood level in two (before and 4 months after intervention) times. Results In the experimental group of the students the mean age was 13.85 + 1.72 years and in the controlled group was 13.60 + 1.81 years. Moreover, there was no significant difference in the PRECEDE constructs, and nutritional behaviors preventing iron deficiency anemia before the intervention in two groups of study. However, the experimental group showed a significant increase 4 months after the intervention. Also, there was no significant difference in the mean score of hemoglobin, hematocrit, and ferritin blood level between the two groups before the intervention. However, in ferritin level, a significant increase was shown in 4 months after the intervention in the experiential group. Conclusions Based on results, the nutrition intervention education base on PRECEDE model has a positive effect to improve iron deficiency anemia preventive behaviors in female students.


1993 ◽  
Vol 33 (6) ◽  
pp. 661-661
Author(s):  
Helena U Suzuki ◽  
Mauro B Morais ◽  
Jose N Corral ◽  
Ulisses Fagundes-Neto ◽  
Nelson L Machado

PEDIATRICS ◽  
1963 ◽  
Vol 31 (6) ◽  
pp. 1041-1044
Author(s):  
LOUIS K DIAMOND ◽  
J. LAWRENCE NAIMAN ◽  
DONALD M. ALLEN ◽  
FRANK A. OSKI,

Experience with a new oral iron-carbohydrate complex (Jefron) in the treatment of iron-deficiency anemia shows that the therapeutic results are inferior to those obtainable with ferrous sulfate. Many children showed no response after months of treatment with this drug and when subsequently placed on ferrous sulfate therapy showed a rapid rise in hemoglobin to normal levels. Preliminary studies suggest that poor gastrointestinal absorption may be a factor in the inadequate therapeutic effects.


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