Effect of Gall Bladder Retrieval via Epigestric Vs Umbilical Port in Laparoscopic Cholectystectomy

Background and Aim: The retrieval of the gallbladder is a key event in laparoscopic cholecystectomy and significantly contributes to postoperative infections and pain. The GB is extracted through an umbilical or epigastric port. The goal of this single-center study was to compare GB retrieval via epigastric versus umbilical port in terms of postoperative site pain and infections. Materials and Methods:In this single-center study, 60 Cholelithiasis patients under went laparoscopic cholectystectomy (LC) for symptomatic gallbladder disease during the period from November 2020 to April 2021 at surgery department of Gambat Institute of Medical Sciences, Gambat Sindh Pakistan. The patients were selected out of the operating room for GB retrieval via umbilical port (Group-I with n = 30) versus epigastric port (Group-II with n = 30) randomly.All 60 patients had routine blood tests such as CBC, SGOT, SGPT, PT, and urine examinations. Until their bowels recovered, all of the patients were kept nil by mouth and on parenteral fluids. They were closely monitored in the post-operative period, with special attention paid to recording the pulse rate, temperature, and level of pain on a 24-hour basis. Results:Chronic Cholecystitis patients chosen randomly from the cholecystectomy list to have their gallbladder delivered through an umbilical or epigastric port.Group I had median pain (IQR) of 5 (1.5), 4 (1), and 2 (1) when compared to group II's median pain (IQR) of 4 (1), 2 (1), and 1 (0.5) one day after the procedure (p-value=0.001), at the time of hospital discharge (p-value0.001), and one month post-surgery (p-value0.001).In group B, there was a clear regression in postoperative pain from the day of surgery until a month later (p-value0.001). Conclusion:According to our findings, umbilical ports are preferable to epigastric ports in terms of post-operative pain, but there is an increased port site infection and hernia risk. Keywords:Cholecystectomy, Umbilical port, Epigastric port, Gall bladder retrieval, Laparoscopic.

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Acute kidney injury with consumption of raw gall bladder of Indian carp fish ( Labeo rohita) : A single center study from India

Nephrology ◽

10.1111/nep.13199 ◽

2018 ◽

Vol 24 (1) ◽

pp. 47-49

Author(s):

Amresh Krishna ◽

Prit P Singh ◽

Harsh Vardhan ◽

Om Kumar ◽

Govind Prasad

Keyword(s):

Acute Kidney Injury ◽

Gall Bladder ◽

Labeo Rohita ◽

Kidney Injury ◽

Single Center ◽

Single Center Study ◽

Carp Fish ◽

Center Study

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Treatment of Chronic Plaque Psoriasis with Etanercept and Methotrexate

Iraq Medical Journal ◽

10.22317/imj.v4i4.966 ◽

2020 ◽

Vol 4 (4) ◽

Author(s):

Rana Khalid Obeed ◽

Husam Ali Salman

Keyword(s):

Plaque Psoriasis ◽

Base Line ◽

Single Center ◽

Chronic Plaque Psoriasis ◽

Group I ◽

Statistical Effect ◽

Single Center Study ◽

Unknown Reason ◽

Pasi Score ◽

Center Study

Objectives: The aim of study is to assess the efficacy of methotrexate and etanercept in the treatment of chronic plaque psoriasis. Methods: This therapeutic, interventional comparative single center study was carried out at the Center of Dermatology and Venereology, Baghdad Teaching Hospital, from January 2015 –July 2017. A total of 62 patients were enrolled; divided in to two groups. Group I: Thirty three patients (23 males and 10 females), their ages ranged between15 and 65 years mean ±SD 33.13±13.07, recieved etanercept 50mg twice weekly for 3 months then once weekly thereafter. Group II: Twenty nine patients (19 males and 10 females), their ages ranged between15 and 62 years mean ± SD 38.16±15.2 ,received methotrexate 15 mg per week for six monthes then tapered. Both groups were followed up monthly for 6 months and their PASI score, DLQI, side effect and pictures were recorded. Results: Seven patients defaulted from the study for unknown reason,30 patients completed in etanercept group, while 25 patients completed in methotrexate group. After 12 weeks the PASI score decrease from base line 19.13±10.67 to 6.38±4.96 and then to 3.34±5.38 after 24 weeks treatment with Etanercept compaired to reduction in PASI score from base line 18.97±10.54 to 5.72± 4.8 to 2.95±-6.01 after 12 weeks and 24 weeks respectively. There is significant statistical effect in the two groups. Conclusions: both are effective monotherapy for patients with moderate to severe plaque psoriasis with tolerable side effects.

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Comparison of MRI Visualization Following Minimally Invasive and Open TLIF: A Retrospective Single-Center Study

Diagnostics ◽

10.3390/diagnostics11050906 ◽

2021 ◽

Vol 11 (5) ◽

pp. 906

Author(s):

Vadim A. Byvaltsev ◽

Andrei A. Kalinin ◽

Morgan B. Giers ◽

Valerii V. Shepelev ◽

Yurii Ya. Pestryakov ◽

...

Keyword(s):

Minimally Invasive ◽

Single Center ◽

Muscle Area ◽

Multifidus Muscle ◽

Postoperative Mri ◽

Group I ◽

Single Center Study ◽

Mr Artifacts ◽

Transpedicular Screw Fixation ◽

Center Study

Analysis of magnetic resonance image (MRI) quality after open (Op)-transforaminal interbody fusion (TLIF) and minimally invasive (MI)-TLIF with the implantation of structurally different systems has not previously been performed. The objective of this study was to conduct a comparative analysis of the postoperative MRI following MI and Op one-segment TLIF. Material and Methods: The nonrandomized retrospective single-center study included 80 patients (46 men and 24 women) aged 48 + 14.2 years. In group I (n = 20) Op-TLIF with open transpedicular screw fixation (TSF) was performed, in II group (n = 60), the MI-TLIF technique was used: IIa (n = 20)—rigid interspinous stabilizer; IIb (n = 20)—unilateral TSF and contralateral facet fixation; IIc (n = 20)—bilateral TSF. Results: Comparison of the quality of postoperative imaging in IIa and IIb subgroups showed fewer MRI artifacts and a significantly greater MR deterioration after Op and MI TSF. Comparison of the multifidus muscle area showed less atrophy after MI-TLIF and significantly greater atrophy after Op-TLIF. Conclusion: MI-TLIF and Op-TLIF with TSF have comparable postoperative MR artifacts at the operative level, with a greater degree of muscle atrophy using the Op-TLIF. Rigid interspinous implant and unilateral TSF with contralateral facet fixation have less artifacts and changes in the multifidus muscle area.

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Intravitreal Injections and Face Masks: Endophthalmitis Risk Before and During the COVID-19 Pandemic

10.21203/rs.3.rs-1124994/v1 ◽

2021 ◽

Author(s):

Saeed Karimi ◽

Amir Mohammadzadeh ◽

Alireza Ramezani ◽

Iman Ansari ◽

Hosein Nouri ◽

...

Keyword(s):

Intravitreal Bevacizumab ◽

Intravitreal Injections ◽

P Value ◽

Single Center ◽

Single Center Study ◽

Baseline Values ◽

Center Study

Abstract In this retrospective, single-center study, the records of patients with acute endophthalmitis following intravitreal bevacizumab (IVB) injections during the pre-COVID and COVID-19 eras were reviewed and compared. A total of 28,085 IVB injections were performed during the pre-COVID era; nine eyes of nine patients developed acute post-IVB endophthalmitis in this era, giving an overall incidence of 0.032% (3.2 in 10000 injections). In the COVID era, a total of 10,717 IVB injections were performed; four eyes of four patients developed acute post IVB endophthalmitis in this era, giving an overall incidence of 0.037% (3.7 in 10000 injections). The incidences of post-IVB endophthalmitis during these two eras were not different (P-value = 0.779). The BCVA of the eyes affected during the COVID era showed poor improvement back to baseline values, after three months, even with prompt and maximum treatment. Face masking protocols seem unlikely to increase the risk of post-IVB endophthalmitis.

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Effect of Remdesivir on mortality and length of stay in hospitalized COVID-19 patients: A single center study

Pakistan Journal of Medical Sciences ◽

10.12669/pjms.38.icon-2022.5779 ◽

2021 ◽

Vol 38 (ICON-2022) ◽

Author(s):

Quratulain Shaikh ◽

Samreen Sarfaraz ◽

Anum Rahim ◽

Mujahid Hussain ◽

Rabeea Shah ◽

...

Keyword(s):

Length Of Stay ◽

Sofa Score ◽

Length Of Hospital Stay ◽

P Value ◽

Single Center ◽

Creative Commons ◽

Single Center Study ◽

The Difference ◽

And Gender ◽

Center Study

Objectives: To see the difference in mortality among hospitalized COVID-19 patients given Remdesivir (RDV) with those who were not given RDV. Methods: A prospective cohort study was conducted on patients who were admitted to the COVID-19 isolation unit at The Indus Hospital, Korangi Campus Karachi between March and June 2020. Results: Groups were similar in age and gender distribution. RDV group was more hypoxic, had severe ARDS and needed higher Oxygen support compared to non-RDV group (p=0.000). Median SOFA score was 2 in RDV vs 5 in non-RDV (p=0.000). More than moderate COVID pneumonia was found in 92% of the RDV group while 89% of non-RDV group (p value=0.001). Median day of illness to administer Remdesivir was 10. There was no difference in mortality (45.5% in RDV vs 40.4% in non-RDV; p=0.4) between the two groups. Median length of hospital stay was 12 days (IQR=7.5-14.5) in RDV group compared to 10 days (IQR=6-14) in non-RDV group (p=0.009). Conclusion: RDV did not show any difference in in-hospital mortality in our patients. More patients had severe ARDS in the RDV group while patients in the non-RDV group had higher SOFA score and multi-organ failure. Length of stay was longer in patients receiving Remdesivir. doi: https://doi.org/10.12669/pjms.38.ICON-2022.5779 How to cite this:Shaikh Q, Sarfaraz S, Rahim A, Hussain M, Shah R, Soomro S. Effect of Remdesivir on mortality and length of stay in hospitalized COVID-19 patients: A single center study. Pak J Med Sci. 2022;38(2):405-410. doi: https://doi.org/10.12669/pjms.38.ICON-2022.5779 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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