scholarly journals Fetomaternal Outcome in Placental Abruption

2021 ◽  
Vol 15 (8) ◽  
pp. 1971-1974
Author(s):  
Sadaf Siddique ◽  
Huma Afridi ◽  
Beenish Riaz ◽  
Itaat Ullah Khan Afridi
Keyword(s):  
Partial Thromboplastin Time ◽  
Placental Abruption ◽  
Post Partum ◽  
Neonatal Morbidity ◽  
Fetal Outcome ◽  
Activated Partial Thromboplastin Time ◽  
Foetal Outcome ◽  
Labour Ward ◽  
Post Partum Haemorrhage ◽  
Grade 3

Background: Placental abruption is a major contributor to obstetrical haemorrhage and a major cause of perinatal mortality in developing countries. This has been done to an attempt to recognize this condition at an earlier stage, prevent its complications and properly manage the complications if they do occur. Aim: To determine maternal and fetal outcome in females with placental abruption. Methods: Hundred patients with confirmed diagnosis of placental abruption were divided in three categories according to the grade of placental abruption. Their baseline investigations including blood group, haemoglobin and coagulation profile i.e. partial thromboplastin time, activated partial thromboplastin time, serum fibrinogen and FDP's were performed and recorded for each category separately. The effect of each grade of abruption was studied on maternal and fetal outcome as well as extent of coagulation disturbance. Results: The results of the study show that 66% babies were delivered alive and 34% were IUD/stillbirth. Gestational age at presentation was important in fetal outcome. Out of 30 babies presenting before 32 weeks of gestation 66% were IUD/stillbirth. 58% patients delivered vaginally and 42% had caesarean section. 32% patients had grade I abruption, 34% patients had grade 3 abruption. 18% patients had post-partum haemorrhage. Conclusion: All professionals working in labour ward must be aware of the causes, presentation and complications of disease and appropriate measures taken in time can help reduce the maternal and neonatal morbidity and mortality. Keywords: Placental abruption, maternal outcome, foetal outcome, coagulation disturbance

Effect of Anemia on Pregnancy Outcome in Labour Ward: Study in a Tertiary Level Public Hospital

2020 ◽  
Vol 11 (2) ◽  
pp. 155-160
Author(s):  
Ayesa Perveen ◽  
Fatema Ashraf ◽  
Rooh E Zakaria ◽  
Rabeya Khanam ◽  
AKM Zahirul Haq ◽  
...  
Keyword(s):  
Pregnancy Outcome ◽  
Public Hospital ◽  
Nuclear Family ◽  
Post Partum ◽  
Educational Status ◽  
Fetal Outcome ◽  
Tertiary Level ◽  
Cross Sectional ◽  
Moderate Anemia ◽  
Labour Ward

Objectives: To determine the pregnancy outcome among anemic women admitted in labour ward of a tertiary level hospital. Methodology: This is a descriptive type of cross-sectional study. All women who were admitted at labour room for delivery with anemia and gestational age more than 28 weeks were included with purposive sampling under the GU-3 of Shaheed Suhrawardy Medical College & Hospital. Respondents were recruited on the basis of clinical findings correlating with lab investigation. Blood samples were collected during the time of admission and hemoglobin (Hb) level were tested by automated machine in the laboratory of ShSMCH. Outcome of pregnancy was observed against the anemic state defined by Hb% done in laboratory. The mother who delivered, intra-partum & post-partum observation up to 7 days were made for pregnancy outcome.Results: This study conducted in a tertiary level public hospital, included 100 pregnant anemic mothers admitted at labor ward. Prevalence of anemia was 30.12% among the pregnant women at delivery. It revealed that women went into labor having mild anemia in 77% and moderate anemia in 23% cases. Importantly it was observed that moderate anemia was found more in younger age group. Additionally, it was also more pronounced (>50%) among the illiterate and primary education group. There was significant inverse relationship between educational status (p =.003) and anemia. Regarding family history, about two thirds anemic mother came from nuclear family and they also lives with small members. Most of the multigravida women presented with moderate anemia. Among the moderately anemic mothers’ interval of pregnancy were less than two years. It has been observed that 60.9% moderate anemic mother was not on regular antenatal checkup and total 11% respondents had no antenatal checkup. Regarding maternal outcome preterm labour (PTL), premature rupture of membrane (PROM), wound infection were more among moderately anemic group. There was significant relationship between degree of anemia with birth weight (p=.014). Adverse fetal outcome like prematurity, NICU admission, IUD were found more among moderately anemic mothers. J Shaheed Suhrawardy Med Coll, December 2019, Vol.11(2); 155-160

scholarly journals Comparison of Pregnancy outcome among Placenta Previa and Abruption

2016 ◽  
Vol 11 (1) ◽  
Author(s):  
Shamsa Humayun ◽  
Fehmida Nahid
Keyword(s):  
Renal Failure ◽  
Cesarean Section ◽  
Pregnancy Outcome ◽  
Placental Abruption ◽  
Placenta Previa ◽  
Neonatal Morbidity ◽  
Fetal Outcome ◽  
Operative Delivery ◽  
Cesarean Hysterectomy ◽  
Poor Pregnancy Outcome

The objective of study was to compare the pregnancy outcome among placenta previa& placental abruption. Study Design: A retrospective analysis of pregnancies complicated by placenta previa or abruption, from January 2003 to December 2003. Results A poor fetal outcome was more frequent in cases of abruption (56.6%) than placenta previa (20%) Prematurity was significantly high in abruption (63.3)%than in placenta previa (40%).cesarean section rate was high in placenta previa(98%) compared to (20%) in abruption. Renal failure PPH and cesarean hysterectomy were the major complications in both groups. Conclusion: Women with abruption had poor pregnancy outcome than placenta previa They were more likely to deliver prematurely with high neonatal morbidity and mortality. Operative delivery was more common in placenta previa.

Outcomes of singleton and twin breech deliveries in a ten year (2005 to 2014) retrospective audit at two rural hospitals in Papua New Guinea’s Gulf Province

2015 ◽  
Vol 1 (2) ◽  
pp. 85
Author(s):  
Richard James Carpenter ◽  
Glen Liddell Mola
Keyword(s):  
Perinatal Death ◽  
Post Partum ◽  
Surrogate Marker ◽  
Neonatal Morbidity ◽  
Rural Setting ◽  
Resource Poor Setting ◽  
Intrauterine Death ◽  
Breech Delivery ◽  
Retrospective Audit ◽  
Post Partum Haemorrhage

<p><span style="text-decoration: underline;">Introduction</span><em> </em>The aim of this audit was to investigate the rates of breech-related perinatal death and maternal and neo-natal morbidity in a resource-poor setting where caesarean sections are difficult to perform. <span style="text-decoration: underline;">Method</span><em>. </em>An audit of 5,102 babies born at two rural Papua New Guinean hospitals, Kapuna and Kikori, from 2005 to 2014 inclusive was performed. Information was gathered from the facility obstetric registers and supplemented by Kikori Hospital’s surgical register. During the period there were 179 breech presentations (103 singletons, 76 twins). The primary outcome was defined as perinatal death. Secondary outcomes were neonatal morbidity and maternal post-partum haemorrhage. Exclusion criteria were applied prior to analysis. These included: Likely pre-labour intrauterine death; mother presenting to hospital in second or third stage; baby born before arrival at hospital; prematurity recorded in the notes or birth weight less than 1500g as a surrogate marker; significant fetal abnormality; and significant maternal medical condition. <span style="text-decoration: underline;">Findings</span><em>. </em>The adjusted incidence of the outcomes were: Perinatal death for vaginal breech singletons 235/1,000 (95% CI 158-336/1,000) and vaginal breech twins 31/1,000 (95% CI 9-107/1,000); neonatal morbidity for vaginal breech singletons 141/1,000 (95% CI 82-231/1,000) and vaginal breech twins 31/1,000 (95% CI 9-107/1,000); post-partum haemorrhage for vaginal breech singletons 129/1,000 (95% CI 74-217/1,000) and vaginal breech twins 230/1,000 (95% CI 137-361/1,000). <span style="text-decoration: underline;">Conclusions</span><em>. </em>Poor outcomes for singleton vaginal breech delivery at the two hospitals were common. The potential in the rural setting for increased education on safe trial of vaginal breach delivery as well as increasing access to caesarean sections deserves consideration. </p>

scholarly journals Fetal Outcome varies with different grades of Placental Abruption

2016 ◽  
Vol 9 (1) ◽  
Author(s):  
Zaheera Saadia ◽  
Aamir Zaman Khan ◽  
Fehmida Nahid
Keyword(s):  
Placental Abruption ◽  
Good Condition ◽  
Fetal Outcome ◽  
P Value ◽  
Intrauterine Death ◽  
Aggressive Approach ◽  
Time Period ◽  
Grade 3 ◽  
One Year ◽  
A Prospective Study

This is a prospective study carried out in Gynae unit-1 of Sir Ganga Ram Hospital, Lahore over a time period of one year. We aimed to find out the prevalence of abruptio placenta in the hospital population and compare the fetal outcome with different grades of placental abruption. Student t test was applied to assess the degree of significance. P value < 0.05 was considered as significant. Complications observed were intrauterine death (IUD), Intrauterine growth retardation (IUGR), Prematurity and fetal anemia. Placental abruption accounted for 2% of hospital obstetrical population. Adverse fetal outcome was observed with Grade 3-4 abruption as compared to abruption of Grade 0-1. Statistically significant numbers of fetuses had no complication with Grade 0-1 abruption and were delivered in good condition (table-1). We concluded that a more aggressive approach is required to manage abruption of Grade 3-4 and observational strategy should be considered for Grade 0-1.

scholarly journals Comparative study of maternal and foetal outcome in instrumental vaginal deliveries

2017 ◽  
Vol 6 (11) ◽  
pp. 4945
Author(s):  
Mariyam S. Ahmed ◽  
Anand N. Bhalerao
Keyword(s):  
Post Partum ◽  
Neonatal Morbidity ◽  
Chi Square ◽  
Perineal Tears ◽  
Vacuum Device ◽  
Vaginal Deliveries ◽  
Significant Difference ◽  
Chi Square Test ◽  
Foetal Outcome ◽  
Labour Room

Background: The art of instrumental vaginal delivery is fading as more and more obstetricians resort to caesarean sections. Instrumental deliveries are deliveries accomplished with the use of vacuum device or forceps. Once either is applied to the foetal head, outward traction generates forces that augment maternal pushing to deliver the foetus vaginally. Objective of present study was to compare the maternal and foetal outcome of forceps versus ventouse delivery.Methods: It was a prospective observational study conducted in Sassoon Hospital between January 2014 to January 2015. A total of 120 cases, 60 each of forceps and ventouse, admitted in labour room were included in the study. Maternal and neonatal morbidity were compared in terms of perineal lacerations, episiotomy extension, post-partum haemorrhage, Apgar score, instrumental injuries. Chi square test and z test of proportion was used to analyze the data.Results: Maternal morbidity, namely episiotomy extension as well as perineal tears were significant in the forceps group. With regards to neonatal morbidity, no statistically significant difference was noted.Conclusions: Vacuum and forceps should remain appropriate tools in the armamentarium of the modern obstetrician. However, ventouse may be chosen first (if there is no foetal distress) as it is significantly less likely to injure the mother.

Monitoring Heparin Therapy: Relationships between the Activated Partial Thromboplastin Time and Heparin Assays Based on Ex-Vivo Heparin Samples

1990 ◽  
Vol 63 (01) ◽  
pp. 016-023 ◽  
Author(s):  
A M H P van den Bessekaar ◽  
J Meeuwisse-Braun ◽  
R M Bertina
Keyword(s):  
Partial Thromboplastin Time ◽  
Plasma Sample ◽  
Ex Vivo ◽  
Correlation Coefficients ◽  
Heparin Therapy ◽  
Thromboembolic Disease ◽  
Activated Partial Thromboplastin Time ◽  
Venous Thromboembolic Disease ◽  
Venous Thromboembolic

SummaryFive different APTT reagents, two amidolytic anti-ITa assays, one amidoiytic anti-Xa assay, and one coagulometric anti-Xa/ anti-IIa assay were used to assess the effect of heparin in patients treated for venous thromboembolic disease. Good correlations were observed between lug-transformed APYE> determined with the various reagents (correlation coefficients: 0.92-0.96).Nevertheless there were important differences in the slopes of the lines of relationship between the APTT reagents.Good correlations were observed between the anti-Xa and anti-IIa assay results (correlation coefficients: 0.92-0.97). However, the amidolytic anti-Xa activity was significantly higher (p <0.001) than the two amidolytic anti-IIa activities. Less good correlations were observed between the log-transformed APTTs and the anti-Xa or anti-IIa activities (correlation coefficients: 0.64-0.78). The correlations were improved by transforming the APTT into APTT-ratio, i.e. the ratio of the patient’s APTT to the same patient’s APTT after removal of heparin from the plasma sample by means of ECTEOLA-cellulose treatment. The correlation coefficients of log (AFTT-ratio) with anti-Xa or anti-IIa ranged from 0.76 to 0.87.For both APTT and amidolytic heparin assay, the response to in vitro heparin was different from the response to ex vivo heparin.Therefore, equivalent therapeutic ranges should be assessed by using ex vivo samples rather than in vitro heparin. Because of the response differences between the APTT reagents, it is not adequate to define a therapeutic range for heparin therapy without specification of the reagent.

Monitoring Anticoagulant Therapy by Activated Partial Thromboplastin Time: Hirudin Assessment

1994 ◽  
Vol 72 (05) ◽  
pp. 685-692 ◽  
Author(s):  
Michael T Nurmohamed ◽  
René J Berckmans ◽  
Willy M Morriën-Salomons ◽  
Fenny Berends ◽  
Daan W Hommes ◽  
...  
Keyword(s):  
Whole Blood ◽  
Partial Thromboplastin Time ◽  
Ex Vivo ◽  
Fold Increase ◽  
Heparin Therapy ◽  
Activated Partial Thromboplastin Time ◽  
Recombinant Hirudin ◽  
Interindividual Differences ◽  
The Relationship

SummaryBackground. Recombinant hirudin (RH) is a new anticoagulant for prophylaxis and treatment of venous and arterial thrombosis. To which extent the activated partial thromboplastin time (APTT) is suitable for monitoring of RH has not been properly evaluated. Recently, a capillary whole blood device was developed for bed-side monitoring of the APTT and it was demonstrated that this device was suitable to monitor heparin therapy. However, monitoring of RH was not evaluated.Study Objectives. To evaluate in vitro and ex vivo the responsiveness and reproducibility for hirudin monitoring of the whole blood monitor and of plasma APTT assays, which were performed with several reagents and two conventional coagulometers.Results. Large interindividual differences in hirudin responsiveness were noted in both the in vitro and the ex vivo experiments. The relationship between the APTT, expressed as clotting time or ratio of initial and prolonged APTT, and the hirudin concentration was nonlinear. A 1.5-fold increase of the clotting times was obtained at 150-200 ng/ml plasma. However, only a 2-fold increase was obtained at hirudin levels varying from 300 ng to more than 750 ng RH/ml plasma regardless of the assays. The relationship linearized upon logarithmic conversion of the ratio and the hirudin concentration. Disregarding the interindividual differences, and presuming full linearity of the relationship, all combinations were equally responsive to hirudin.Conclusions. All assays were equally responsive to hirudin. Levels up to 300 ng/ml plasma can be reliably estimated with each assay. The manual device may be preferable in situations where rapid availability of test results is necessary.

In Vitro Thrombogenicity Tests of Factor IX Concentrates

1979 ◽  
Vol 42 (05) ◽  
pp. 1355-1367 ◽  
Author(s):  
C V Prowse ◽  
A Chirnside ◽  
R A Elton
Keyword(s):  
Factor Viii ◽  
Partial Thromboplastin Time ◽  
Generation Time ◽  
Activated Partial Thromboplastin Time ◽  
Factor Ix ◽  
In Vitro Tests ◽  
Factor Viii Inhibitor ◽  
Factor Ixa ◽  
Viii Inhibitor

SummaryVarious factor IX concentrates have been examined in a number of in vitro tests of thrombogenicity. The results suggest that some tests are superfluous as in concentrates with activity in any of these tests activation is revealed by a combination of the non-activated partial thromboplastin time, the thrombin (or Xa) generation time and factor VIII inhibitor bypassing activity tests. Assay of individual coagulant enzymes revealed that most concentrates contained more factor IXa than Xa. However only a small number of concentrates, chiefly those that had been purposefully activated, contained appreciable amounts of either enzyme.

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