A case-control study on passive smoking and coronary heart disease in never-smoking women in Xi'an, China

1997 ◽  
Author(s):  
Yao He
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Passive Smoking ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Prediction of coronary heart disease incidence in a general male population by circulating non-coding small RNA sRNY1-5p in a nested case–control study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Vera L. Costa ◽  
Jean-Bernard Ruidavets ◽  
Vanina Bongard ◽  
Bertrand Perret ◽  
Emanuela Repetto ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Small Rna ◽  
Case Control Study ◽  
Disease Incidence ◽  
Case Control ◽  
Male Population ◽  
General Male Population ◽  
Nested Case Control ◽  
Control Study

AbstractDuring the development of atherosclerotic lesion, s-RNYs (small RNAs of about 24/34 nucleotides) are derived by the processing of long Ro-associated non-coding RNAs (RNYs) in macrophages. The levels of serum s-RNYs have been found significantly upregulated in patients with coronary heart disease (CHD) compared to age-matched CHD-free individuals. The present study aimed to examine the predictive value of serum s-RNYs for CHD events in the general male population. Within the frame of nested-case–control study, the GENES study, we measured the absolute expression of a RNY-derived small RNA, the s-RNY1-5p, in the serum of individuals (without CHD at baseline) who encountered a CHD event within 12 years of follow-up (n = 30) (Cases) and compared them to individuals who remained event-free (Controls) (n = 30). The expression of s-RNY1-5p in serum was significantly upregulated in Cases compared to Controls (p = 0.027). The proportion of CHD event-free was significantly higher among individuals with serum s-RNY1-5p below the median value (631 molecules/mL). In a multivariable model adjusted for age, smoking, hypertension, diabetes and dyslipidemia, the risk of CHD events increased more than fourfold in individuals with serum s-RNY1-5p above the median value (HR, 4.36; 95% CI 1.22–15.60). A positive association with CHD events was also observed when considering s-RNY1-5p as a continuous variable (p = 0.022). Based on our results, we conclude that serum s-RNY1-5p is an independent predictor of CHD events in a general male population and might be a relevant biomarker for early detection of cardiovascular diseases.

Antioxidant potential of diet: Association between dietary antioxidant index and odds of coronary heart disease: A case-control study

2021 ◽  
pp. 1-13
Author(s):  
Farhad Vahid ◽  
Zahra Nasiri ◽  
Amir Abbasnezhad ◽  
Ezatollah Fazeli Moghadam
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Antioxidant Capacity ◽  
Case Control Study ◽  
Case Control ◽  
P Value ◽  
Dietary Antioxidants ◽  
Dietary Antioxidant ◽  
The Relationship ◽  
Control Study

BACKGROUND: Oxidative stress and chronic inflammation are among the leading causes of coronary heart disease (CHD). Studies investigated the relationship between dietary antioxidants and the risk/odds of CHD, and contradictory results have been reported. Dietary antioxidant index (DAI) is a novel and reliable nutritional tool that examines the diet’s overall antioxidant capacity. Its validity was examined using serum total antioxidant capacity and malondialdehyde. OBJECTIVE: This study aimed to investigate the relationship between DAI score and odds of CHD. METHODS: In this incidence case-control study, 320 individuals with a definitive diagnosis of CHD and 320 participants without CHD or related risk factors attending the same hospitals/polyclinics were selected as the case and control groups. We estimated the DAI by summing up six standardized intakes of major dietary antioxidants, including manganese, vitamin E, A, C, selenium, and zinc. RESULTS: Modeling DAI categorized according to the median (–0.38), in multi-adjusted model showed a significant protective association with the odd of CHD (OR = 0.72; 95%CI:0.51–0.99, p-value = 0.05). Also, modeling DAI as a continuous variable in multi-adjusted models (OR = 0.94;95%CI:0.90–0.95; p-value = 0.01) showed significant results. CONCLUSION: Using the DAI to investigate the relationship between dietary antioxidants and CHD can show more realistic results than a single study of antioxidants.

scholarly journals Human AGT -p.Met268Thr and coronary heart disease risk: a case-control study and meta-analysis

2018 ◽  
Vol 20 (1) ◽  
pp. 17-24
Author(s):  
Hanieh Mohammadi ◽  
Narges Razavi ◽  
Ali Abbasi ◽  
Faezeh Babaei ◽  
Ensiyeh Seyedrezazadeh ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Coronary Heart Disease Risk ◽  
Case Control Study ◽  
Disease Risk ◽  
Meta Analysis ◽  
Case Control ◽  
Heart Disease Risk ◽  
Control Study

Religion, Spirituality and Risk of Coronary Heart Disease: A Matched Case–Control Study and Meta-Analysis

2018 ◽  
Vol 58 (4) ◽  
pp. 1203-1216 ◽  
Author(s):  
Rohoullah Hemmati ◽  
Zeinab Bidel ◽  
Milad Nazarzadeh ◽  
Maryam Valadi ◽  
Somayeh Berenji ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Case Control Study ◽  
Meta Analysis ◽  
Case Control ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

scholarly journals Coronary Heart Disease and ABO Blood Group in Diabetic Women: A Case-Control Study

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Seyyed Hasan langari ◽  
Adele Bahar ◽  
Leila Asadian ◽  
Saeid Abediankenai ◽  
Seyed Shojaeddin Namazi ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Blood Group ◽  
Case Control Study ◽  
Case Control ◽  
Abo Blood Group ◽  
Control Study

scholarly journals Association of CDKN2BAS Polymorphism rs4977574 with Coronary Heart Disease: A Case-Control Study and a Meta-Analysis

2014 ◽  
Vol 15 (10) ◽  
pp. 17478-17492 ◽  
Author(s):  
Yi Huang ◽  
Huadan Ye ◽  
Qingxiao Hong ◽  
Xuting Xu ◽  
Danjie Jiang ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Case Control Study ◽  
Meta Analysis ◽  
Case Control ◽  
Control Study
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