scholarly journals Rheumatic and congenital heart diseases among school children of Khon Kaen, Thailand: declining prevalence of rheumatic heart disease

2014 ◽  
Vol 8 (5) ◽  
pp. 645-650 ◽  
Author(s):  
Arnkisa Chaikitpinyo ◽  
Manat Panamonta ◽  
Yuttapong Wongswadiwat ◽  
Wiboon Weraarchakul ◽  
Ouyporn Panamonta ◽  
...  

AbstractBackground: Rheumatic fever (RF), rheumatic heart disease (RHD), and congenital heart disease (CHD) are still major problems among Thai school children.Objective: To examine trends in the prevalence of RF/RHD and CHD along with the socioeconomic status of school children in urban Khon Kaen, northeastern Thailand.Methods: We conducted cross-sectional survey of 8,555 school children aged 5-15 years from 4 schools in urban Khon Kaen from January to March 2006. Pediatric cardiologists examined the school children and all cardiac diagnoses were confirmed by echocardiography. Socioeconomic data were also collected. Schools were divided into high and low socioeconomic status (SES) schools, based on the prevailing levels of parental education and household income. All positive cases of heart disease were followed and reviewed at a university hospital up to December 2013.Results: Of 8,555 children examined, 2 had RF/RHD, and 10 had CHD. The prevalence of RF/RHD was 0.23 per 1,000 (95% CI 0.03-0.84), and the prevalence of CHD was 1.2 per 1,000 (95% CI 0.56-2.15). Prevalence of RF/RHD among urban school children in the center of northeastern Thailand had declined from 1.13 to 0.23 per 1,000 since 1986. The indices of socioeconomic development revealed marked improvement during this 20 year interim. The prevalence of RF/RHD was higher among low SES schools (4.6 per 1,000) compared with high SES schools (0 per 1,000).Conclusion: There is a low prevalence of RHD in school children in this region compared with the period before 1986.

1969 ◽  
Vol 14 (11) ◽  
pp. 387-388
Author(s):  
A. S. Rogen

It is common knowledge that rheumatic fever and rheumatic heart disease have fallen in frequency but comparison of the two sets of figures quoted in the text is impressive in stressing that the degree of this is perhaps greater than has been generally realised; at the same time, more children with congenital heart disease are living to school age. Since rheumatic heart disease at the school age group did not make any demand on the cardiac surgeon, it follows that increased demands are made on him by the changing pattern of heart disease in school children.


2014 ◽  
Vol 10 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Dipanker Prajapati ◽  
Deewakar Sharma ◽  
Prakash Raj Regmi ◽  
Harihar Khanal ◽  
Sajan Gopal Baidya ◽  
...  

Background and Aims: Rheumatic Fever, Rheumatic Heart Disease and Congenital Heart disease are the most common cardiac problems in school children. Prior studies have reported different prevalence rate of Rheumatic Heart Disease among different groups of population of Nepal. The aim of this study was to estimate the prevalence of Rheumatic Fever, Rheumatic Heart Disease and Congenital Heart Disease among school children in Kathmandu Valley of Nepal. Methods: Cardiac screening of 34,876 school children from 115 randomly selected public schools from two cities of Kathmandu Valley (Kathmandu and Lalitpur) was done. Cases with abnormal findings in auscultation underwent echocardiography and the diagnosis was confirmed. Results: The prevalence of Congenital Heart Disease was noted to be 1 per thousand and prevalence of Rheumatic Heart Disease was found to be 0.90 per thousand (in the age group 5-16 years) with the most common lesion being Mitral Regurgitation. No significant statistical difference was noted between male and female students in both the cases of Rheumatic Heart Disease and Congenital Heart Disease. No cases of Acute Rheumatic Fever were noted. Conclusion: The prevalence of Rheumatic Heart Disease among school children in Kathmandu valley was noted to be lower than reported in similar previous studies. Primary and secondary prevention programs of RF/RHD have been effective in Nepal and are needed to be strengthened and expanded to further reduce the burden of these diseases. Nepalese Heart Journal | Volume 10 | No.1 | November 2013| Pages 1-5 DOI: http://dx.doi.org/10.3126/njh.v10i1.9738


2010 ◽  
Vol 27 (4) ◽  
pp. 448-453 ◽  
Author(s):  
Maneesha Bhaya ◽  
Sadik Panwar ◽  
Rajesh Beniwal ◽  
Raja Babu Panwar

2021 ◽  
Vol 38 ◽  
Author(s):  
Melaku Bimerew ◽  
Biruk Beletew ◽  
Addisu Getie ◽  
Adam Wondmieneh ◽  
Getnet Gedefaw ◽  
...  

1999 ◽  
Vol 81 (4) ◽  
pp. 372-372 ◽  
Author(s):  
A. C STEER ◽  
J. ADAMS ◽  
J. CARLIN ◽  
T. NOLAN ◽  
F. SHANN

2020 ◽  
Vol 28 (3) ◽  
pp. 147-151
Author(s):  
Neha Sharma ◽  
Devinder Toor ◽  
Lokajeet Baro ◽  
Mriganka S Chaliha ◽  
Giriraj Kusre ◽  
...  

Background Rheumatic heart disease is a major global health concern, especially in low- and middle-income countries. The pathogenesis is attributable to an aberrant immune response, host genetic factors, and socioeconomic status. The objective of this study was to screen HLA-DQB1 alleles as genetic susceptibility markers in rheumatic heart disease patients in Assam, North East India, and to correlate the predominant allele with socioeconomic status and clinical profile. Methods A case-control study of 100 echocardiography-confirmed rheumatic heart disease patients and age- and sex-matched healthy controls from Assam Medical College and Hospital was conducted. Human leukocyte antigen typing was performed using HLA-DQ typing kit. A questionnaire was designed to study the socioeconomic status and clinical profile of rheumatic heart disease patients. Results Among the 9 alleles studied, HLA-DRBQ1*03:01 was found to be the statistically significant predominant allele in this population, especially in the Ahom ethnic group. In the HLA-DRBQ1*03:01-positive population, rural dwelling was found to be a significantly increased risk factor for rheumatic heart disease. Among severe cases, 90% of mitral stenosis, 40% of mitral regurgitation, and 33.3% of aortic regurgitation cases were HLA-DRBQ1*03:01-positive. Also, 50% of aortic valve thickening and 36.8% of mitral valve thickening cases were found in this population. Conclusion Our data suggest that HLA-DRBQ1*03:01 is a significant susceptibility marker in this population, and predominant in the rural population. Furthermore, it may play an important role in determining the pattern of valve damage in rheumatic heart disease patients.


BMJ Open ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. e036827 ◽  
Author(s):  
Bárbara Martins Bechtlufft ◽  
Bruno Ramos Nascimento ◽  
Craig Sable ◽  
Clara Leal Fraga ◽  
Márcia Melo Barbosa ◽  
...  

ObjectivesEchocardiographic (echo) screening is an important tool to estimate rheumatic heart disease (RHD) prevalence, but the natural history of screen-detected RHD remains unclear. The PROVAR+ (Programa de RastreamentO da VAlvopatia Reumática) study, which uses non-experts, telemedicine and portable echo, pioneered RHD screening in Brazil. We aimed to assess the mid-term evolution of Brazilian schoolchildren (5–18 years) with echocardiography-detected subclinical RHD and to assess the performance of a simplified score consisting of five components of the World Heart Federation criteria, as a predictor of unfavourable echo outcomes.SettingPublic schools of underserved areas and private schools in Minas Gerais, southeast Brazil.ParticipantsA total of 197 patients (170 borderline and 27 definite RHD) with follow-up of 29±9 months were included. Median age was 14 (12–16) years, and 130 (66%) were woman. Only four patients in the definite group were regularly receiving penicillin.Primary and secondary outcome measuresUnfavourable outcome was based on the 2-year follow-up echo, defined as worsening diagnostic category, remaining with mild definite RHD or development/worsening of valve regurgitation/stenosis.ResultsAmong patients with borderline RHD, 29 (17.1%) progressed to definite, 49 (28.8%) remained stable, 86 (50.6%) regressed to normal and 6 (3.5%) were reclassified as other heart diseases. Among those with definite RHD, 13 (48.1%) remained in the category, while 5 (18.5%) regressed to borderline, 5 (18.5%) regressed to normal and 4 (14.8%) were reclassified as other heart diseases. The simplified echo score was a significant predictor of RHD unfavourable outcome (HR 1.197, 95% CI 1.098 to 1.305, p<0.001).ConclusionThe simple risk score provided an accurate prediction of RHD status at 2-year follow-up, showing a good performance in Brazilian schoolchildren, with a potential value for risk stratification and monitoring of echocardiography-detected RHD.


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