scholarly journals Relationship between spirituality and suicidal ideations among patients with major depressive disorder

2018 ◽  
Vol 9 (4) ◽  
pp. 113
Author(s):  
Souzan Abd El-Menem Abd El-Ghafar Harfus ◽  
Amal Awad Abd El-Nabi Moussa ◽  
Samar Mabrook El-Nehrawy
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Negative Correlation ◽  
Meaning In Life ◽  
Significant Negative Correlation ◽  
Structured Interview ◽  
Major Depressive ◽  
Correlational Design ◽  
Psychiatric Department ◽  
The Relationship

Background and objective: Suicide still constitutes to be a critical and risky issue requiring preventive strategies. There is evidence to suggest that spirituality is vital to the process of discovering meaning in life and plays an important role in dealing with suicidal desire. The aim of this study was to investigate the relationship between spirituality and suicidal ideations among patients with major depressive disorder.Methods: Design and participants: A descriptive correlational design was utilized in the current study. A purposive sample of 181 patients with major depressive disorder was recruited. Setting: The study was conducted at inpatient psychiatric department of Tanta University and Neurology, Psychiatry, and Neuro-Surgery Center. Both hospitals are under the supervision and direction of the ministry of higher education. Tools: Four tools were used to collect data; socio-demographic and clinical characteristics structured interview schedule, Beck Depression Inventory, Daily Spiritual Experience Scale, and Scale for Suicide Ideation.Results: The current study indicated a statistical significant negative correlation between depression and spirituality. Also, a statistical significant negative correlation was found between spirituality and one subscale of suicide which is active suicide desire subscale. On the other side, there was a statistical significant positive correlation between depression and total score of suicide.Conclusions: Higher levels of spirituality may help buffer risk of active suicide desire and promote protective effect against depression. Recommendation: interventions that aim at increasing spiritual involvement and practice may be beneficial in reducing depressive symptoms and suicide desire.

scholarly journals Gut microbiome, a potential indicator for differential diagnosis of major depressive disorder and general anxiety disorder

2020 ◽  
Author(s):  
Zaiquan Dong ◽  
Xiaoling Shen ◽  
Yanni Hao ◽  
Jin Li ◽  
Haoran Li ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Differential Diagnosis ◽  
Anxiety Disorder ◽  
Depressive Disorder ◽  
Negative Correlation ◽  
Gut Microbiome ◽  
Significant Negative Correlation ◽  
Major Depressive ◽  
General Anxiety Disorder ◽  
General Anxiety

Abstract Background Major depressive disorder (MDD) and general anxiety disorder (GAD) share many common features, leading to many challenges in their differential diagnosis. Given the importance of the microbiota-gut-brain axis, we aimed to investigate the differences in gut microbiota between representative cases of these two diseases and sought to develop a microbiome-based approach for their differential diagnosis.Methods We enrolled 23 patients with MDD, 21 patients with GAD, and 10 healthy subjects (health control, HC) in the present study. We used 16S rRNA gene sequencing analysis to determine the microbial compositions of gut microbiome based on Illumina Miseq according to Illumina’s standard protocol.Results We found that patients with MDD or GAD exhibited significant differences in the relative abundance of gut microbiota. We identified the microbial signatures of subjects with MDD and GAD relative to HC and found differences in levels of Faecalibacterium and LachnospiraceaeND3007group. Moreover, we also found correlations between the bacteria and neuroendocrine and clinical symptoms, namely, a significant negative correlation between Fusicatenibacter and free thyroxine(FT4) in MDD, significant negative correlation between Fusicatenibacter and cortisol (PTC) in GAD, positive correlation between LachnospiraceaeND3007group and sleep disturbance factor of Hamilton Depression Rating Scale, and negative correlation between LachnospiraceaeND3007group and PTC (all P<0.05).Conclusions The present study elucidated a unique gut microbiome signature associated with MDD and GAD that could facilitate differential diagnosis and targeted therapy.

The relationship of olfactory function and clinical traits in major depressive disorder

2020 ◽  
Vol 386 ◽  
pp. 112594
Author(s):  
Fang Wang ◽  
Xiaohui Wu ◽  
Jerry Gao ◽  
Yongchao Li ◽  
Yuncheng Zhu ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Olfactory Function ◽  
Major Depressive ◽  
Relationship Of ◽  
The Relationship

scholarly journals The relationship between rumination and sleep quality in patients with major depressive disorder

2020 ◽  
Vol 7 (2) ◽  
pp. 26-36
Author(s):  
Samira Yadollahifar ◽  
Amir Sadeghi ◽  
Farshid Shamsaei ◽  
◽  
◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Sleep Quality ◽  
Major Depressive ◽  
The Relationship

A simpler definition of major depressive disorder

2009 ◽  
Vol 40 (3) ◽  
pp. 451-457 ◽  
Author(s):  
M. Zimmerman ◽  
J. N. Galione ◽  
I. Chelminski ◽  
J. B. McGlinchey ◽  
D. Young ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Somatic Symptoms ◽  
Structured Interview ◽  
Major Depressive ◽  
Medically Ill ◽  
Treatment Providers ◽  
Dsm Iv ◽  
Definition Of ◽  
High Level

BackgroundThe DSM-IV symptom criteria for major depressive disorder (MDD) are somewhat lengthy, with many studies showing that treatment providers have difficulty recalling all nine symptoms. Moreover, the criteria include somatic symptoms that are difficult to apply in patients with medical illnesses. In a previous report, we developed a briefer definition of MDD that was composed of the mood and cognitive symptoms of the DSM-IV criteria, and found high levels of agreement between the simplified and full DSM-IV definitions. The goal of the present study was to replicate these findings in another large sample of psychiatric out-patients and to extend the findings to other patient samples.MethodWe interviewed 1100 psychiatric out-patients and 210 pathological gamblers presenting for treatment and 1200 candidates for bariatric surgery. All patients were interviewed by a diagnostic rater who administered a semi-structured interview. We inquired about all symptoms of depression for all patients.ResultsIn all three samples high levels of agreement were found between the DSM-IV and the simpler definition of MDD. Summing across all 2510 patients, the level of agreement between the two definitions was 95.5% and the κ coefficient was 0.87.ConclusionsAfter eliminating the four somatic criteria from the DSM-IV definition of MDD, a high level of concordance was found between this simpler definition and the original DSM-IV classification. This new definition offers two advantages over the current DSM-IV definition – it is briefer and it is easier to apply with medically ill patients because it is free of somatic symptoms.

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