scholarly journals Imaging pattern and histological features of Gorham-Stout Disease of the radius

2018 ◽  
Vol 8 (2) ◽  
pp. 20 ◽  
Author(s):  
Clemence Bruyere ◽  
Valentina Garibotto ◽  
Anne Laure Rougemont ◽  
Sana Boudabbous
Keyword(s):  
Conventional Radiography ◽  
Imaging Modalities ◽  
Unknown Etiology ◽  
Active Lesion ◽  
Histological Features ◽  
Positron Emission ◽  
Ultrasound Computed Tomography ◽  
Soft Tissue Involvement ◽  
Rare Location ◽  
Magnetic Resonance Imaging Mri

Gorham-Stout Disease (GD) is a very rare disease of unknown etiology characterized by progressive osteolysis and soft tissue involvement. Imaging is non-specific, and diagnosis may be delayed. The evolution of the disease is unpredictable, with progression of the osteolysis, spontaneous regression, or in a few cases re-ossification. We report a case of a 54-year-old woman with GD of the radius. In this rare location, only few cases have been reported with all imaging modalities: conventional radiography, ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET-CT). We describe the characteristics of GD in different imaging modalities, as well as the histological features. To the best of our knowledge, we report the first metabolically active lesion in GD, with relevant implications for the differential diagnosis.

scholarly journals Assessment of Cardiac Sarcoidosis with Advanced Imaging Modalities

2014 ◽  
Vol 2014 ◽  
pp. 1-15 ◽  
Author(s):  
Makoto Orii ◽  
Toshio Imanishi ◽  
Takashi Akasaka
Keyword(s):  
Fdg Pet ◽  
Cardiac Sarcoidosis ◽  
Systemic Disease ◽  
Imaging Modalities ◽  
Unknown Etiology ◽  
Advanced Imaging ◽  
Multiple Organs ◽  
Positron Emission ◽  
Magnetic Resonance Imaging Mri ◽  
Diagnostic Modalities

Sarcoidosis is a chronic systemic disease of unknown etiology that is characterized by the presence of noncaseating epithelioid granulomas, usually in multiple organs. Several studies have shown that sarcoidosis might be the result of an exaggerated granulomatous reaction after exposure to unidentified antigens in genetically susceptible individuals. Cardiac involvement may occur and lead to an adverse outcome: the heart mechanics will be affected and that causes ventricular failure, and the cardiac electrical system will be disrupted and lead to third degree atrioventricular block, malignant ventricular tachycardia, and sudden cardiac death. Thus, early diagnosis and treatment of this potentially devastating disease is critically important. However, sensitive and accurate imaging modalities have not been established. Recent studies have demonstrated the promising potential of cardiac magnetic resonance imaging (MRI) and18F-fluoro-2-deoxyglucose positron emission tomography (18F-FDG PET) in the diagnosis and assessment of cardiac sarcoidosis (CS). In this review, we discuss the epidemiology, etiology, histological findings, and clinical features of sarcoidosis. We also introduce advanced imaging including18F-FDG PET and cardiac MRI as more reliable diagnostic modalities for CS.

scholarly journals Unusual Location for Langerhans Cell Histiocytosis: Basisphenoid extended to Parapharyngeal Space

2016 ◽  
Vol 8 (1) ◽  
pp. 38-40
Author(s):  
Asif Salimov ◽  
Ahmet E Suslu ◽  
Serdar Ozer ◽  
Taner Yilmaz ◽  
Hatice IY Bajin
Keyword(s):  
Langerhans Cell Histiocytosis ◽  
Parapharyngeal Space ◽  
Langerhans Cell ◽  
Unknown Etiology ◽  
Endoscopic Endonasal ◽  
Unusual Location ◽  
First Case ◽  
Rare Location ◽  
Magnetic Resonance Imaging Mri ◽  
The Right

ABSTRACT Langerhans cell histiocytosis (LCH) is a rare disease with unknown etiology involving abnormal proliferation of histiocytes. We hereby describe an LCH that has a rare location. A 4-year-old female patient was referred to our clinic with headache lasting for 2 months. Magnetic resonance imaging (MRI) showed an expansile mass on the level of basisphenoid extended to the right parapharyngeal space with dense contrast enhancement. The patient underwent endoscopic endonasal transsphenoidal surgery for biopsy of the mass. Immunohistochemical and pathological studies confirmed LCH diagnosis. This is the first case report of LCH extended to the parapharyngeal space in the current literature. How to cite this article Salimov A, Suslu AE, Ozer S, Yilmaz T, Bajin HIY. Unusual Location for Langerhans Cell Histiocytosis: Basisphenoid extended to Parapharyngeal Space. Int J Otorhinolaryngol Clin 2016;8(1):38-40.

scholarly journals In vivo imaging of chronic active lesions in multiple sclerosis

2020 ◽  
pp. 135245852095858
Author(s):  
Alberto Calvi ◽  
Lukas Haider ◽  
Ferran Prados ◽  
Carmen Tur ◽  
Declan Chard ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Tissue Injury ◽  
Clinical Activity ◽  
Active Lesion ◽  
Dynamic Contrast Enhancement ◽  
Positron Emission ◽  
Research Goal ◽  
Imaging Markers ◽  
Magnetic Resonance Imaging Mri

New clinical activity in multiple sclerosis (MS) is often accompanied by acute inflammation which subsides. However, there is growing evidence that a substantial proportion of lesions remain active well beyond the acute phase. Chronic active lesions are most frequently found in progressive MS and are characterised by a border of inflammation associated with iron-enriched cells, leading to ongoing tissue injury. Identifying imaging markers for chronic active lesions in vivo are thus a major research goal. We reviewed the literature on imaging of chronic active lesion in MS, focussing on ‘slowly expanding lesions’ (SELs), detected by volumetric longitudinal magnetic resonance imaging (MRI) and ‘rim-positive’ lesions, identified by susceptibility iron-sensitive MRI. Both SELs and rim-positive lesions have been found to be prognostically relevant to future disability. Little is known about the co-occurrence of rims around SELs and their inter-relationship with other emerging techniques such as dynamic contrast enhancement (DCE) and positron emission tomography (PET).

Positron Emission Tomography Imaging of Meningioma in Clinical Practice

Neurosurgery ◽  
2011 ◽  
Vol 70 (4) ◽  
pp. 1033-1042 ◽  
Author(s):  
Jan Frederick Cornelius ◽  
Karl Josef Langen ◽  
Gabriele Stoffels ◽  
Daniel Hänggi ◽  
Michael Sabel ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Pet Imaging ◽  
Positron Emission Tomography Imaging ◽  
Emission Tomography ◽  
Imaging Modalities ◽  
Future Research ◽  
Study Protocols ◽  
Positron Emission ◽  
Magnetic Resonance Imaging Mri

Abstract Meningiomas represent about 20% of intracranial tumors and are the most frequent nonglial primary brain tumors. Diagnosis is based on computed tomography (CT) and magnetic resonance imaging (MRI). Mainstays of therapy are surgery and radiotherapy. Adjuvant chemotherapy is tested in clinical trials of phase II. Patients are followed clinically by imaging. However, classical imaging modalities such as CT and MRI have limitations. Hence, we need supplementary imaging tools. Molecular imaging modalities, especially positron emission tomography (PET), represent promising new instruments that are able to characterize specific metabolic features. So far, these modalities have only been part of limited study protocols, and their impact on clinical routine management is still under investigation. It may be expected that their extended use will provide new aspects about meningioma imaging and biology. In the present article, we summarize PET imaging for meningiomas based on a thorough review of the literature. We discuss and illustrate the potential role of PET imaging in the clinical management of meningiomas. Finally, we indicate current limitations and outline directions for future research.

scholarly journals Imaging in diagnostics and management of extramedullary lesions in a patient with multiple myeloma

2019 ◽  
Vol 1 (1) ◽  
pp. 74-87
Author(s):  
Sergey Kozyrev ◽  
Daniil Korabelnikov ◽  
Vasiliy Pop ◽  
Vladimir Troyan ◽  
Oleg Rukavicyn
Keyword(s):  
Multiple Myeloma ◽  
Peripheral Blood Stem Cell ◽  
Clinical Signs ◽  
Conventional Radiography ◽  
Extramedullary Plasmacytoma ◽  
Nuclear Medicine Imaging ◽  
X Ray ◽  
Positron Emission ◽  
Pet Ct ◽  
Magnetic Resonance Imaging Mri

Extraosseous manifestations are found in less than 5% of patients with multiple myeloma. Involvement of the gastrointestinal system in the course of multiple myeloma (MM) is extremely rare. Imaging is required for correct staging, in the followup after treatment and is predictor of prognosis. Several imaging technologies are used for the diagnosis and management of patients with MM. Conventional radiography, computed tomography (CT), magnetic resonance imaging (MRI) and nuclear medicine imaging - positron emission tomography (PET) combined with CT (PET/CT) and PET combined with MRI (PET/MRI) are all used in clarifying the extent of bone and soft tissue lesions in MM. The brief literature review on extramedullary lesions in MM and their imaging with recommendations is given. We describe the imaging in diagnostics and management of an rare case of secondary extramedullary plasmacytoma (EMP) in relapse involving the pancreas and duodenum with the bleeding in a patient with MM, IgA lambda, stage II, after 6-years treatment with chemotherapy, autologous peripheral blood stem cell transplantation and radiotherapy. EMP was detected by PET/CT before the appearance of obvious clinical signs, and then EMP was monitoring by PET/CT, X-ray and ultrasound.

Imaging the Cardiovascular System: Seeing Is Believing

2005 ◽  
Vol 11 (3) ◽  
pp. 189-199 ◽  
Author(s):  
Thomas K. Borg ◽  
James A. Stewart ◽  
Michael A. Sutton
Keyword(s):  
Cardiovascular System ◽  
Imaging System ◽  
Biological Tissues ◽  
Imaging Modalities ◽  
Cardiovascular Development ◽  
Positron Emission ◽  
Cardiovascular Biology ◽  
Electron Microscopes ◽  
Magnetic Resonance Imaging Mri

From the basic light microscope through high-end imaging systems such as multiphoton confocal microscopy and electron microscopes, microscopy has been and will continue to be an essential tool in developing an understanding of cardiovascular development, function, and disease. In this review we briefly touch on a number of studies that illustrate the importance of these forms of microscopy in studying cardiovascular biology. We also briefly review a number of imaging modalities such as computed tomography, (CT) Magnetic resonance imaging (MRI), ultrasound, and positron emission tomography (PET) that, although they do not fall under the realm of microscopy, are imaging modalities that greatly complement microscopy. Finally we examine the role of proper imaging system calibration and the potential importance of calibration in understanding biological tissues, such as the cardiovascular system, that continually undergo deformation in response to strain.

scholarly journals A literature review on multimodality molecular imaging nanoprobes for cancer detection

2019 ◽  
Vol 25 (2) ◽  
pp. 57-68 ◽  
Author(s):  
Daryoush Shahbazi-Gahrouei ◽  
Pegah Moradi Khaniabadi ◽  
Saghar Shahbazi-Gahrouei ◽  
Amir Khorasani ◽  
Farshid Mahmoudi
Keyword(s):  
Molecular Imaging ◽  
Cancer Detection ◽  
Single Photon ◽  
Imaging Techniques ◽  
Photon Emission ◽  
Emission Tomography ◽  
Imaging Modalities ◽  
Single Photon Emission ◽  
Positron Emission ◽  
Magnetic Resonance Imaging Mri

Abstract Molecular imaging techniques using nanoparticles have significant potential to be widely used for the detection of various types of cancers. Nowadays, there has been an increased focus on developing novel nanoprobes as molecular imaging contrast enhancement agents in nanobiomedicine. The purpose of this review article is to summarize the use of a variety of nanoprobes and their current achievements in accurate cancer imaging and effective treatment. Nanoprobes are rapidly becoming potential tools for cancer diagnosis by using novel molecular imaging modalities such as Ultrasound (US) imaging, Computerized Tomography (CT), Single Photon Emission Tomography (SPECT) and Positron Emission Tomography (PET), Magnetic Resonance Imaging (MRI), and Optical Imaging. These imaging modalities may facilitate earlier and more accurate diagnosis and staging the most of cancers.

scholarly journals Advances in Diagnostic Imaging for Cardiac Sarcoidosis

2021 ◽  
Vol 10 (24) ◽  
pp. 5808
Author(s):  
Osamu Manabe ◽  
Noriko Oyama-Manabe ◽  
Tadao Aikawa ◽  
Satonori Tsuneta ◽  
Nagara Tamaki
Keyword(s):  
Cardiac Sarcoidosis ◽  
Imaging Techniques ◽  
Clinical Manifestations ◽  
Granulomatous Inflammation ◽  
Unknown Etiology ◽  
Lower Sensitivity ◽  
Positron Emission ◽  
Life Threatening ◽  
Magnetic Resonance Imaging Mri ◽  
Enhanced Computed Tomography

Sarcoidosis is a systemic granulomatous disease of unknown etiology, and its clinical presentation depends on the affected organ. Cardiac sarcoidosis (CS) is one of the leading causes of death among patients with sarcoidosis. The clinical manifestations of CS are heterogeneous, and range from asymptomatic to life-threatening arrhythmias and progressive heart failure due to the extent and location of granulomatous inflammation in the myocardium. Advances in imaging techniques have played a pivotal role in the evaluation of CS because histological diagnoses obtained by myocardial biopsy tend to have lower sensitivity. The diagnosis of CS is challenging, and several approaches, notably those using positron emission tomography and cardiac magnetic resonance imaging (MRI), have been reported. Delayed-enhanced computed tomography (CT) may also be used for diagnosing CS in patients with MRI-incompatible devices and allows acceptable evaluation of myocardial hyperenhancement in such patients. This article reviews the advances in imaging techniques for the evaluation of CS.

New Sonographic Imaging Modalities for Carotid Disease Evaluation – A Review

2012 ◽  
Vol 8 (3) ◽  
pp. 158
Author(s):  
Muriel Sprynger ◽  
Keyword(s):  
Imaging Techniques ◽  
Subclinical Atherosclerosis ◽  
Specific Aspect ◽  
Imaging Modalities ◽  
Carotid Disease ◽  
Positron Emission ◽  
Risk Patients ◽  
Magnetic Resonance Imaging Mri ◽  
Sonographic Imaging ◽  
Low Cardiovascular Risk

Several imaging techniques (such as ultrasounds, computed tomography [CT] scan, magnetic resonance imaging [MRI], positron emission tomography [PET] scan, etc.) can provide interesting information on subclinical atherosclerosis and plaque stability. In fact sonographic imaging techniques can be very useful in this field. All of them have their limitations, but each of them has its own specificity and enlights a specific aspect of atherosclerosis – they are complementary. Will it be possible to one day differentiate high-risk from low-risk carotid plaques and stenosis – differentiate high from low cardiovascular risk patients? Who should or should not be treated? This is a major issue for people dealing with atherosclerosis. This article reviews the new sonographic imaging modalities for carotid valuation.

State-of-the-art pulmonary arterial imaging – Part 1

VASA ◽  
2018 ◽  
Vol 47 (5) ◽  
pp. 345-359 ◽  
Author(s):  
Yuki Tanabe ◽  
Luis Landeras ◽  
Abed Ghandour ◽  
Sasan Partovi ◽  
Prabhakar Rajiah
Keyword(s):  
State Of The Art ◽  
Pulmonary Arteries ◽  
Pulmonary Angiography ◽  
Imaging Modalities ◽  
Nuclear Medicine Imaging ◽  
Multiple State ◽  
Pulmonary Arterial ◽  
Magnetic Resonance Imaging Mri ◽  
Acquired Abnormalities ◽  
Arterial Imaging

Abstract. The pulmonary arteries are affected by a variety of congenital and acquired abnormalities. Multiple state-of-the art imaging modalities are available to evaluate these pulmonary arterial abnormalities, including computed tomography (CT), magnetic resonance imaging (MRI), echocardiography, nuclear medicine imaging and catheter pulmonary angiography. In part one of this two-part series on state-of-the art pulmonary arterial imaging, we review these imaging modalities, focusing particularly on CT and MRI. We also review the utility of these imaging modalities in the evaluation of pulmonary thromboembolism.

Sign in / Sign up

Export Citation Format

Share Document