scholarly journals Effects of Low Level Laser Therapy (LLLT) on Serum Values of Interleukin 6 (IL-6) in Patients with Periodontitis and Type 2 Diabetes Mellitus (T2DM)

2021 ◽  
Vol 29 (1) ◽  
pp. 59
Author(s):  
Shefqet Mrasori ◽  
Mirjana Popovska ◽  
Biljana Rusevska ◽  
Mirsad Shkreta ◽  
Ardian Selani ◽  
...  
2020 ◽  
Vol 3 (5) ◽  
pp. 82
Author(s):  
Danik Martirosyan ◽  
Mohammad Reza Ashoori ◽  
Hossein Mirmiranpour

Background: The control and management of type 2 diabetes mellitus is the most important way to prevent health consequences of the disease. Oxidative stress derived from diabetes mellitus is an important cause of these symptoms in uncontrolled diabetic patients. The consumption of functional foods containing antioxidants and trace minerals can help prevent these consequences and control diabetes mellitus.Objective: In this study, we examined whether low-level laser therapy could have an effect on levels of antioxidant enzymes and minerals in the serum of patients with type 2 diabetes mellitus.Methods: Thirty individuals with type 2 diabetes and thirty healthy individuals, as controls, were selected as participants for this study. The levels of antioxidant enzymes glutathione peroxidase, catalase, superoxide dismutase; biochemical parameters, such as glucose and hydrogen peroxide; minerals iron, zinc, magnesium, copper; and selenium binding protein 1 (as an indicator of selenium) were studied before and after low level-laser therapy.Results: The levels of antioxidant enzymes and some minerals significantly increased in control and diabetic patients after low level-laser therapy. The levels of glucose, hydrogen peroxide, and selenium binding protein 1, however, were unchanged after low-level laser therapy.Conclusions: Low level-laser therapy may be an important tool for reducing oxidative stress caused by type 2 diabetes mellitus due to its ability to increase levels of antioxidant enzymes and mineral content.Keywords: Laser Irradiation; Antioxidant; Functional Foods/Bioactive Compounds; Diabetes Mellitus.


2020 ◽  
Vol 11 (4) ◽  
pp. 481-485
Author(s):  
Nermeen Mohamed Abdelhalim ◽  
Walid Kamal Abdelbasset ◽  
Bader Ali Alqahtani ◽  
Ahmed Fathy Samhan

2022 ◽  
Vol 5 (1) ◽  
pp. 1
Author(s):  
Danik M. Martirosyan ◽  
Mohammad Reza Ashoori ◽  
Alireza Rezaeinezhad ◽  
Fahimeh Jahanbakhshi ◽  
Shaghayegh Pezeshki ◽  
...  

Background: Unmanaged type 2 diabetes mellitus has dangerous consequences, such as neuropathy. Oxidative stress and inflammatory factors play an important role in the development of diabetic neuropathy. Diabetics are prone to mild cognitive impairment, which is a neurological disease. The aim of this study was to investigate the effects of quercetin as a functional food and oxidative agents and inflammatory factors of low-level laser.Methods: In this study, 60 elderly volunteers were selected: 30 normal as a control group and 30 with type 2 diabetes mellitus and mild cognitive impairment. The average age was 75 years old. Groups of diabetic patients were examined for changes in glucose levels, oxidants, antioxidants and inflammatory factors before and after treatment with quercetin and low-level laser therapy–green laser diode with a wavelength of 532 nm at 100 mw and compared with the control group. Changes in the levels of biochemical parameters were performed according to the instructions of the relevant kits. Results: The results of the obtained data analysis showed that there was a significant difference (P value < 0.05) in the levels of glucose, hydrogen peroxide, advanced glycation end-products, malondialdehyde, oxidized-low density lipoprotein, paraoxonase, lipoprotein lipase, and inflammatory factors including TNF-α, interleukin-1 alpha and interleukin-1 beta between diabetic samples before and after treatment with quercetin and laser from control subject samples. There was no significant difference (P value > 0.05) in inflammatory factors between quercetin-treated, laser-treated and both quercetin and laser treated groups. The synergistic effect of quercetin and laser between the quercetin and laser treated group and the untreated group on changes in the levels of biochemical parameters was observed significantly only in advanced glycation end-products, malondialdehyde, oxidized-low density lipoprotein, and paraoxonase.Conclusion: The results showed that quercetin, laser, and their synergistic effect can play a role in reducing some oxidant factors.Keywords: Quercetin, Low-level laser, Inflammatory factors, Oxidative factors, Diabetes mellitus


Trials ◽  
2014 ◽  
Vol 15 (1) ◽  
Author(s):  
Cid André Fidelis de Paula Gomes ◽  
Ernesto Cesar Pinto Leal-Junior ◽  
Daniela Aparecida Biasotto-Gonzalez ◽  
Yasmin El-Hage ◽  
Fabiano Politti ◽  
...  

2011 ◽  
Vol 68 (8) ◽  
pp. 684-689 ◽  
Author(s):  
Radmila Obradovic ◽  
Ljiljana Kesic ◽  
Goran Jovanovic ◽  
Dragan Petrovic ◽  
Goran Radicevic ◽  
...  

Background/Aim. There is clear evidence on direct relationship between periodontal disease and diabetes mellitus. Many investigations point out greater prevalence and severity of periodontal disease among diabetic patients. During last decade, low level laser therapy has been used in periodontal therapy. It has biostimulative effect, accelerates wound healing, minimizes pain and swelling, and there is almost no contraindication for its usage. The aim of the paper was to investigate the efficiency of low level laser therapy as adjuvant tool in reduction of gingival inflammation in diabetic patients. Methods. The study incuded 150 participants divided into three groups: group I (50 participants with diabetes mellitus type 1 and periodontal disease), group II (50 participants with diabetes mellitus type 2 and periodontal disease), group III (nondiabetic participants with periodontal disease). Gingival health evaluation was done using gingival index L?e-Silness. Soft and hard deposits were removed, periodontal pockets cleaned and GaAlAs low level laser therapy (5 mW) applied five consecutive days. In each patient, low level laser therapy was not applied on the left side of the jaw in order to compare the effects of the applied therapy. After the first, third and fifth therapy and one month after the last visit gingival index was evaluated. Before the first and after the fifth therapy exfoliative cytology of gingiva was done and nuclei areal was analyzed morphometrically. Results. After all investigated periods, gingival index and nuclei areal were significantly decreased comparing to values before the therapy, at both jaw sides (p < 0.001). After the 1st, 3rd and 5th therapy, the t-test showed a significantly decreased gingival index at the lased side of jaw comparing to non-lased side. Conclusion. Low level laser therapy is efficient in gingival inflammation elimination and can be proposed as an adjuvant tool in basic periodontal therapy of diabetic patients.


2018 ◽  
Vol 7 (1) ◽  
pp. 7
Author(s):  
Abdurachman Abdurachman ◽  
A Rubiyanto ◽  
Suhariningsih Suhariningsih ◽  
Hendromartono Hendromartono ◽  
A Gunawan

2012 ◽  
Vol 28 (1) ◽  
pp. 19-24 ◽  
Author(s):  
Radmila Obradović ◽  
Ljiljana Kesić ◽  
Dragan Mihailović ◽  
Slobodan Antić ◽  
Goran Jovanović ◽  
...  

Author(s):  
VARSHA PALLED ◽  
DR. JITENDRA RAO ◽  
DR. RAGHUWAR DAYAL SINGH ◽  
DR. SHUCHI TRIPATHI ◽  
DR. KALPANA SINGH ◽  
...  

The purpose of this study was to evaluate whether Low-Level Laser Therapy (LLLT) improves the healing of the implant surgical site with clinical and biochemical parameters.Thirty patients with an edentulous space spanning a single tooth were selected. The patients were randomly allocated to two groups - the control group and the test group. The test group received laser energy at a power of 2J/cm 2 with a total of 4-6J energy over each implant. Clinical parameters (Implant Stability Quotient, probing index, modified sulcus bleeding index)and osteoprotegerin (OPG) were assessed at baseline and follow-up intervals (2 weeks, 6 weeks, and 3 months).The test group showed significantly higher implant stability quotient compared to thecontrol group at 2 weeks(57.93±3.95 and 35.67±3.08; p&lt;0.01) and 3months(58.86±3.75 and 67.06±3.78; p&lt;0.01). A significant rise in OPG levels of the test group(686.30±125.36pg/ml at baseline and 784.25±108.30pg/ml at 3months;p&lt;0.01) was seen contrary to significant decline in the control group (839.50±249.08pg/ml at baseline,415.30±78.39pg/ml at 3months;p&lt;0.01). Within the limitations of the study, the study suggests that the healing of peri-implant hard and soft tissues may be enhanced with the use of LLLT as an explicit modality during the post-operative period.


Sign in / Sign up

Export Citation Format

Share Document