scholarly journals Does Ramadan fasting affect glicemic control in patients with diabetes mellitus? effects of fasting on betatrophin and insulin resistance

2022 ◽  
Vol 11 (2) ◽  
pp. 1
Author(s):  
Mustafa Timurkaan ◽  
Esra Timurkaan ◽  
Yilmaz Aslan ◽  
Mehmet Kalayci ◽  
Hakan Ayyildiz
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Ramadan Fasting ◽  
Patients With Diabetes

scholarly journals RELUCTANCE OF PATIENTS WITH DIABETES MELLITUS TO INSULIN THERAPY; PSYCHOLOGICAL INSULIN RESISTANCE

2021 ◽  
Vol 71 (2) ◽  
pp. 602-05
Author(s):  
Umair Ali ◽  
Muhammad Wajid Munir ◽  
Jahanzeb Maqsood ◽  
Mahwash Jamil ◽  
Syed Saif Ur Rehman ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Insulin Therapy ◽  
Demographic Data ◽  
Tertiary Care ◽  
Negative Attitude ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Validated Questionnaire ◽  
Patients With Diabetes

Objective: To evaluate factors resulting in reluctance of initiation of insulin therapy in patients with type 2 diabetes mellitus. Study Design: Cross sectional study. Place and Duration of Study: Medical OPD of a private tertiary care multi-specialty hospital in Islamabad, from Apr to Jul 2019. Methodology: Patients with diabetes mellitus between age of 30-70 years, who had poor glycaemic control on two oral antidiabetic drugs having HbA1c>9% and were insulin naïve, were included in this study. A validated questionnaire was developed which had two sections; first including the demographic data of the study populations and second having closedended dichotomous questions which were asked from patients by the treating physicians Results: A total of 180 patients with diabetes mellitus eligible for insulin therapy were included in the study, among them 52 (28.9%) were agreed to initiate the insulin. Negative attitude and beliefs include painful way of administration 85 (66.4%), difficult insulin storage 98 (76.6%), risk of hypoglycemia 82 (64.1%).The mean negative perception Score was 7.35 (SD 0.98). Conclusion: Psychological insulin resistance is present in significant diabetic population, and it is a big obstacle in insulin therapy initiation and compliance.

scholarly journals INFLUENCE OF BETA-BLOCKERS ON INSULIN RESISTANCE IN PATIENTS WITH DIABETES MELLITUS TYPE 2

2011 ◽  
pp. 23-28 ◽  
Author(s):  
Ivana Damnjanović ◽  
Radmila Veličković-Radovanović ◽  
Radivoj Kocić ◽  
Snežana Zlatković-Guberinić ◽  
Danka Sokolović ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Diabetes Mellitus Type 2 ◽  
Beta Blockers ◽  
Diabetes Mellitus Type ◽  
Patients With Diabetes

scholarly journals Endothelial dysfunction in development of cerebrovascular disorders in patients with diabetes mellitus

2012 ◽  
Vol 15 (1) ◽  
pp. 42-48 ◽  
Author(s):  
Evgenia Pavlovna Kosobyan ◽  
Ivona Renata Yarek-Martynova ◽  
Mikhail Yur'evich Martynov ◽  
Alla Nikolaevna Yasamanova ◽  
Tatiana Ivanovna Kolesnikova
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Cerebral Ischemia ◽  
Endothelial Dysfunction ◽  
Ultrasound Examination ◽  
Cerebrovascular Disorders ◽  
Transcranial Doppler Ultrasound ◽  
Excessive Weight ◽  
Hemodynamic Assessment ◽  
Patients With Diabetes

Endothelial dysfunction and aberrations of haemostasis play an important part in development of cerebrovascular disorders in patientswith diabetes mellitus. Such factors as hyper- and hypoglycemia, hyperinsulinism, insulin resistance and excessive weight affect progressionof microcirculation deficiency and cerebral ischemia. Transcranial Doppler ultrasound examination is useful as a noninvasivemethod of hemodynamic assessment.

scholarly journals A szénhidrát-anyagcsere és a gyulladásos folyamatok jellemzésére szolgáló új marker, a szérumprogranulin diagnosztikai és prognosztikai szerepéről

2019 ◽  
Vol 160 (25) ◽  
pp. 973-979
Author(s):  
Bíborka Nádró ◽  
Ferenc Sztanek ◽  
Hajnalka Lőrincz ◽  
Dénes Páll ◽  
György Paragh ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Serum Levels ◽  
Obesity And Diabetes ◽  
Patients With Diabetes ◽  
Factor Α ◽  
Necrosis Factor ◽  
Reduced Renal Function

Abstract: Progranulin is a recently recognized multifunctional glycopeptide shown to be related to obesity and diabetes mellitus. Progranulin is an endogenous antagonist of tumor necrosis factor-α by competitively binding to its receptor, therefore, it exerts anti-inflammatory activity. Paradoxically, previous studies have shown that serum levels of progranulin were elevated in patients with diabetes and associated to its complications including micro- and macroangiopathies, macroalbuminuria or reduced renal function. Moreover, hyperprogranulinemia may be involved in the pathogenesis of obesity-associated insulin resistance. The review summarizes the currently available data on progranulin as a novel marker of the carbohydrate metabolism and inflammation. Orv Hetil. 2019; 160(25): 973–979.

Serum Irisin and Diabetic Nephropathy in Patients with Diabetes Mellitus

2021 ◽  
Vol 53 (12) ◽  
pp. 825-825
Author(s):  
Tomoyuki Kawada
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Diabetic Nephropathy ◽  
Meta Analysis ◽  
Infiltration Rate ◽  
Fundamental Relationship ◽  
Patients With Diabetes ◽  
The Mean

Dear Editor,I read the article by Wang et al., who conducted a meta-analysis to investigate the association between serum irisin levels and diabetic nephropathy (DN) in patients with type 2 diabetes mellitus (T2DM) 1. The mean serum irisin level in T2DM patients with microalbuminuria was significantly lower than that in T2DM patients with normoalbuminuria. In addition, the mean serum irisin level in T2DM patients with macroalbuminuria was significantly lower than that in T2DM patients with microalbuminuria. Furthermore, the mean serum irisin level in T2DM patients with estimated glomerular infiltration rate (eGFR)<60 ml/min 1.73 m2 was significantly lower than that in T2DM patients with eGFR≥60 ml/min 1.73 m2. The authors concluded that decreased serum irisin level was associated with albuminuria and reduced eGFR in T2DM patients. DN was significantly related to decreased serum irisin level in T2DM patients with dose-response manner. Progression of DN may be considered as advanced DM status, and serum irisin level would reflect glucose intolerance via insulin resistance. I have a comment about their study with special reference to the fundamental relationship between the types of DM and serum irisin levels.

scholarly journals Diabetic macro- and microvascular disease in type 2 diabetes

2007 ◽  
Vol 4 (2_suppl) ◽  
pp. S7-S11 ◽  
Author(s):  
Michel P Hermans
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function ◽  
Microvascular Disease ◽  
Patients With Diabetes

Before a patient develops overt type 2 diabetes mellitus, there is typically a prolonged period of patho-physiological change. In the common form of type 2 diabetes mellitus, there are years of insulin resistance, initially compensated by increased beta cell function, then impaired glucose tolerance develops, and finally type 2 diabetes. We know from studies such as the United Kingdom Prospective Diabetes Study (UKPDS) and the Belfast study that loss of beta cell function and insulin resistance are usually relentless.1, 2 Thus, therapy to reduce blood glucose has to be gradually increased with time for patients with diabetes. What is less well known is that every person has a different slope for beta cell function loss which intersects with insulin resistance.

PP228-SUN GLUTAMINE AND INSULIN RESISTANCE FOR CARDIAC PATIENTS WITH DIABETES MELLITUS

2013 ◽  
Vol 32 ◽  
pp. S109
Author(s):  
S.M. Efremov ◽  
V. Lomivorotov ◽  
V. Shmirev ◽  
D. Ponomarev ◽  
M. Deryagin
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Cardiac Patients ◽  
Patients With Diabetes
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