scholarly journals Inverted papilloma of the ureter: study of a rare case with emphasis on clinicopathologic implications

2012 ◽  
Vol 6 (6) ◽  
pp. 274 ◽  
Author(s):  
Nikolaos Mertziotis ◽  
Diomidis Kozyrakis ◽  
Andreas Petrolekas ◽  
Maria Terzi ◽  
Nikiforos Kapranos
Keyword(s):  
Clinical Course ◽  
Endoscopic Examination ◽  
Inverted Papilloma ◽  
Renal Unit ◽  
Macroscopic Hematuria ◽  
Papilloma Virus ◽  
Polymerase Chain ◽  
Consensus Primers ◽  
Ureteral Lesion ◽  
Tomography Scan

A 62-year old male patient presented complaining of intermittent macroscopic hematuria. The ultrasonographic investigation revealed a hydronephrosis of remarkable degree with indiscreterenal parenchyma. The abdominal computed tomography scan identified a ureteral lesion with proximal dilatation, hydronephrosis and a functionless ipsilateral renal unit. The retrograde urography showed a 4-cm lesion with multiple filling defects and a smooth contour. The endoscopic examination showed an exophytic lesion, highly suspicious for malignancy. Urine cytology revealed atypia. Right nephroureterectomy was performed and the pathology revealed a ureteral inverted papilloma (UIP). Polymerase chain reaction examination for the presence of human papilloma virus, using GP5+/6+ consensus primers, was negative. The presence UIP should be considered in patients with urotheleal lesions in the ureter when the diagnostic workup for malignancy is inconclusive. The clinical course of the disease seems to be favorable.

Human papilloma virus detection in liquid cytology, in situ hybridization and polymerase chain reaction

2005 ◽  
Vol 446 (2) ◽  
pp. 202-203 ◽  
Author(s):  
F. Alameda ◽  
L. Pijuan ◽  
L. Ferrer ◽  
M. L. Mari�oso ◽  
M. Muset ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
In Situ Hybridization ◽  
Human Papilloma Virus ◽  
Virus Detection ◽  
Chain Reaction ◽  
Papilloma Virus ◽  
Polymerase Chain

scholarly journals The influence of the SARS-CoV-2 pandemic on esophagogastric cancer services: an international survey of esophagogastric surgeons

2020 ◽  
Vol 33 (7) ◽  
Author(s):  
Sivesh K Kamarajah ◽  
Sheraz R Markar ◽  
Pritam Singh ◽  
Ewen A Griffiths ◽  
Keyword(s):  
Online Survey ◽  
International Survey ◽  
Definitive Chemoradiotherapy ◽  
Available N ◽  
Cancer Management ◽  
Cancer Services ◽  
Esophagogastric Cancer ◽  
Polymerase Chain ◽  
Practice Variations ◽  
Tomography Scan

Abstract Background Several guidelines to guide clinical practice among esophagogastric surgeons during the COVID-19 pandemic were produced. However, none provide reflection of current service provision. This international survey aimed to clarify the changes observed in esophageal and gastric cancer management and surgery during the COVID-19 pandemic. Methods An online survey covering key areas for esophagogastric cancer services, including staging investigations and oncological and surgical therapy before and during (at two separate time-points—24th March 2020 and 18th April 2020) the COVID-19 pandemic were developed. Results A total of 234 respondents from 225 centers and 49 countries spanning six continents completed the first round of the online survey, of which 79% (n = 184) completed round 2. There was variation in the availability of staging investigations ranging from 26.5% for endoscopic ultrasound to 62.8% for spiral computed tomography scan. Definitive chemoradiotherapy was offered in 14.8% (adenocarcinoma) and 47.0% (squamous cell carcinoma) of respondents and significantly increased by almost three-fold and two-fold, respectively, in both round 1 and 2. There were uncertainty and heterogeneity surrounding prioritization of patients undergoing cancer resections. Of the surgeons symptomatic with COVID-19, only 40.2% (33/82) had routine access to COVID-19 polymerase chain reaction testing for staff. Of those who had testing available (n = 33), only 12.1% (4/33) had tested positive. Conclusions These data highlight management challenges and several practice variations in caring for patients with esophagogastric cancers. Therefore, there is a need for clear consistent guidelines to be in place in the event of a further pandemic to ensure a standardized level of oncological care for patients with esophagogastric cancers.

scholarly journals Total Endovascular Aortic Arch Repair with Branched Graft

Aorta ◽  
2019 ◽  
Vol 07 (04) ◽  
pp. 121-124
Author(s):  
Ilaria Franzese ◽  
Giuseppe Petrilli ◽  
Giovanni Puppini ◽  
Daniela Bacich ◽  
Vincenzo Giambruno ◽  
...  
Keyword(s):  
Aortic Arch ◽  
Clinical Course ◽  
Computed Tomography Scan ◽  
Aortic Arch Replacement ◽  
Total Aortic Arch Replacement ◽  
Custom Made ◽  
Aortic Arch Repair ◽  
Branched Graft ◽  
Bovine Aortic Arch ◽  
Tomography Scan

AbstractIn selected cases, the utilization of branched endografts for the treatment of aortic arch aneurysms could be a safe and advantageous alternative to high-risk procedures such as open total aortic arch replacement or hybrid arch repair. We present the case of a 70-year-old man with saccular aneurysm of a bovine aortic arch which was endovascularly treated using a double-branched custom-made aortic endoprosthesis based on the Relay NBS (Non-Bare Stent) Plus platform intended for zone 0 deployment. The postoperative clinical course was uneventful. The postoperative computed tomography scan showed a good result of the implant. The patient was discharged 6 days after the procedure.

Prevalence and typing of human papilloma virus (HPV) among female sex workers and outpatient women in southern Thailand

Sexual Health ◽  
2006 ◽  
Vol 3 (1) ◽  
pp. 11 ◽  
Author(s):  
Verapol Chandeying ◽  
Suzanne M. Garland ◽  
Sepehr N. Tabrizi
Keyword(s):  
Human Papilloma Virus ◽  
Sex Workers ◽  
Enzyme Linked Immunosorbent Assay ◽  
Easy Method ◽  
Papilloma Virus ◽  
Sexually Transmitted ◽  
Southern Thailand ◽  
Consensus Primers ◽  
Virus Typing

Background: Thai sex workers (SW) have high rates of sexually transmitted infections (STIs); however, detection and treatment is often complicated by accessibility to sensitive and accurate diagnostic tests. Self-sampling of women combined with molecular amplification techniques could help in accurate diagnosis, treatment and follow-up of such women. Detection of persistent high-risk human papilloma virus (HPV) in such populations could also be beneficial in identifying women who may need more frequent follow-up for cervical cytology screening. The current study aimed to examine the prevalence of HPV in this population and compare this with the lower-risk outpatient women (OPW) in Thailand. Methods: Four hundred and thirty OPW and 524 Thai SW were sampled by a self-administered tampon collection. Cells were extracted from tampons and, subsequently, women underwent routine vaginal examination for detection of other STIs. Detection of HPV was performed by polymerase chain reaction (PCR) using the L1 consensus primers, followed by L1 consensus probe using an in-house PCR-enzyme-linked immunosorbent assay (ELISA). All positive samples were typed using PCR-ELISA and type-specific oligonucleotide probes. Results: Overall, HPV was detected in 20/430 (4.6%) and 120/524 (22.9%) in OPW and SW respectively. Over 98% of samples produced a β-globin signal, indicating adequately collected samples. Human papilloma virus typing probes detected HPV16 or 18 in 14% and 26% of the positive samples from OPW and SW respectively. HPV31, 33, 35 or 39 were detected in 19% and 12% and HPV45, 51 or 52 in 9.5% and 4% of positive OPW and SW patients respectively. Low risk HPV6 or 11 were detected in 1% and 4.9% of OPW and SW respectively. Conclusion: There was a significantly higher HPV prevalence in Thai SW than OPW, with the majority (21%) of positive samples containing the oncogenic HPV16 or 18 DNA. The results indicate that PCR could serve as a rapid and easy method for identification of women who require more frequent screening for cervical cancer.

Uptake of exogenous human papilloma virus L1 DNA by oocytes and detection by the polymerase chain reaction

1992 ◽  
Vol 9 (6) ◽  
pp. 531-533 ◽  
Author(s):  
Philip J. Chan ◽  
Brian C. Su ◽  
Donald R. Tredway ◽  
Majid Seraj ◽  
Ibrahim M. Seraj ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Human Papilloma Virus ◽  
Chain Reaction ◽  
Papilloma Virus ◽  
Polymerase Chain

scholarly journals Cavernous hemangioma of the lung

2011 ◽  
Vol 64 (5-6) ◽  
pp. 327-330 ◽  
Author(s):  
Aleksandra Lovrenski ◽  
Milana Panjkovic ◽  
Zivka Eri ◽  
Istvan Klem ◽  
Golub Samardzija ◽  
...  
Keyword(s):  
Cavernous Hemangioma ◽  
Clinical Course ◽  
Bronchial Biopsy ◽  
Immunohistochemical Examination ◽  
Massive Haemoptysis ◽  
Cavernous Hemangiomas ◽  
Asymptomatic Case ◽  
The Right ◽  
Tomography Scan ◽  
Mediastinal Pleura

Introduction. Cavernous hemangiomas are benign vascular tumours rarely described in the lungs. Symptoms include respiratory distress, cardiac failure and massive haemoptysis, but they are mostly asymptomatic. Case report. A 67-year-old woman was referred to our institute and treated for pneumonia. A computed tomography scan of the thorax showed an infiltrative mass about 46mm in its greatest dimension in the right upper lobe. The mass was in contact with the mediastinal pleura. Since bronchial biopsy and FNAC did not reveal the aetiology of the lesion, the video-assisted thoracic surgery with right anterolateral thoracotomy and enucleation was performed. The intraoperative and postoperative patohistological study showed cavernous hemangioma and this diagnosis was confirmed on immunohistochemical staining. Conclusion. In spite of its benign behaviour and mostly asymptomatic clinical course it is necessary to consider cavernous hemangioma in the differential diagnosis of other pulmonary lesions. The definitive diagnosis can be made only by histopathological and immunohistochemical examination.

2′,5′-Oligoadenylate synthetase activity analysis and human papilloma virus typing as prognostic factors in patients with recurrent respiratory papillomatosis

2004 ◽  
Vol 118 (10) ◽  
pp. 750-756 ◽  
Author(s):  
V. Gerein ◽  
E. Rastorguev ◽  
J. Gerein ◽  
E. Lodemann ◽  
H. Pfister ◽  
...  
Keyword(s):  
Human Papilloma Virus ◽  
Interferon Alpha ◽  
Clinical Course ◽  
Recurrent Respiratory Papillomatosis ◽  
Synthetase Activity ◽  
Oligoadenylate Synthetase ◽  
Papilloma Virus ◽  
Interferon Alpha Therapy ◽  
Alpha Therapy

Objective: Determination of early prognostic factors in patients with recurrent respiratory papillomatosis is extremely important, so the major goal of our prospective, multicentre study was to evaluate (1) the feasibility of various factors to determine prognosis of the clinical course,as well as (2) the response to interferon-alpha therapy in recurrent respiratory papillomatosis. Methods: Forty-two patients with recurrent respiratory papillomatosis were treated with interferon-alpha (3 MU/m2 three times per week; mean therapy duration was 2.7 ± 1.8 years)in 1983–1994 and followed-up until 2003. Human papilloma virus (HPV) type, recurrent respiratory papillomatosis severity and 2′,5′-oligoadenylate synthetase activity were determined by standard methods and analysed for correlation with the results of long-term clinical outcome.Results and conclusion: Patients with HPV type 11, a severity score >4, a high number of surgical procedures prior to interferon-alpha therapy and a high basal 2′,5′-oligoadenylate synthetase activity should be considered at high risk of an aggressive clinical course, often with spread to lower airway passages, malignant transformation and death. Human papilloma virus type, score for recurrent respiratory papillomatosis severity, number of surgical procedures and 2′,5′-oligoadenylate synthetase activity showed significant association with response to interferon-alpha therapy and the long-term clinical course, so these factors have value in predicting prognosis in recurrent respiratory papillomatosis.

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