Prevalence and typing of human papilloma virus (HPV) among female sex workers and outpatient women in southern Thailand

Sexual Health ◽  
2006 ◽  
Vol 3 (1) ◽  
pp. 11 ◽  
Author(s):  
Verapol Chandeying ◽  
Suzanne M. Garland ◽  
Sepehr N. Tabrizi

Background: Thai sex workers (SW) have high rates of sexually transmitted infections (STIs); however, detection and treatment is often complicated by accessibility to sensitive and accurate diagnostic tests. Self-sampling of women combined with molecular amplification techniques could help in accurate diagnosis, treatment and follow-up of such women. Detection of persistent high-risk human papilloma virus (HPV) in such populations could also be beneficial in identifying women who may need more frequent follow-up for cervical cytology screening. The current study aimed to examine the prevalence of HPV in this population and compare this with the lower-risk outpatient women (OPW) in Thailand. Methods: Four hundred and thirty OPW and 524 Thai SW were sampled by a self-administered tampon collection. Cells were extracted from tampons and, subsequently, women underwent routine vaginal examination for detection of other STIs. Detection of HPV was performed by polymerase chain reaction (PCR) using the L1 consensus primers, followed by L1 consensus probe using an in-house PCR-enzyme-linked immunosorbent assay (ELISA). All positive samples were typed using PCR-ELISA and type-specific oligonucleotide probes. Results: Overall, HPV was detected in 20/430 (4.6%) and 120/524 (22.9%) in OPW and SW respectively. Over 98% of samples produced a β-globin signal, indicating adequately collected samples. Human papilloma virus typing probes detected HPV16 or 18 in 14% and 26% of the positive samples from OPW and SW respectively. HPV31, 33, 35 or 39 were detected in 19% and 12% and HPV45, 51 or 52 in 9.5% and 4% of positive OPW and SW patients respectively. Low risk HPV6 or 11 were detected in 1% and 4.9% of OPW and SW respectively. Conclusion: There was a significantly higher HPV prevalence in Thai SW than OPW, with the majority (21%) of positive samples containing the oncogenic HPV16 or 18 DNA. The results indicate that PCR could serve as a rapid and easy method for identification of women who require more frequent screening for cervical cancer.


2017 ◽  
Vol 90 (3) ◽  
pp. 564-570 ◽  
Author(s):  
Johanna Mäki ◽  
Henrik Paavilainen ◽  
Katja Kero ◽  
Veijo Hukkanen ◽  
Stina Syrjänen


2003 ◽  
Vol 88 (3) ◽  
pp. 345-350 ◽  
Author(s):  
Benny Almog ◽  
Ronni Gamzu ◽  
Michael J Kuperminc ◽  
Ishai Levin ◽  
Ofer Fainaru ◽  
...  


Author(s):  
Shetty Theertha S. ◽  
Priya Kamath

Background: Assessment of knowledge and awareness regarding human papilloma virus and cervical cancer among medical students.Methods: Questionnaire based prospective study of 200 III and IV year consenting medical students willing to be a part of the study. 25 questions were in the questionnaire and they were asked to tick in front of the answer which they felt was correct. 3 questions regarding demographic details were formulated. To assess knowledge, attitude and practice total of 10, 8 and 4 questions were formulated respectively. Score of 0, 1, 2 and 3 were given to answers for statistical analysis.Results: A 110 (55%) belonged to III year and 90 (45%) belonged to IV year. 112 (56%) were females and 88 (44%) were males. 180 (90%) were aware regarding agent causing cervical cancer. 77.8% of IV MBBS and all students of III MBBS knew the etiology. 98% knew the screening technique while 190 (95%) knew that vaccine availability for cervical cancer. 60% knew that the infection was sexually transmitted, and majority knew it is not curable with antibiotics. 70% knew route of administration while most were unaware about age of administration. 91% had not taken the vaccine while 41.5% would if offered. 73% knew the vaccine is ineffective against other STD’s and most agreed that vaccine should be in the national immunization schedule. 40% knew that men should be vaccinated while 79% would recommend it to others.Conclusions: Primary prevention of cervical cancer with vaccination is a novel concept. Health professionals can play a role in propagating this practice. Syllabus in medical schools must emphasize on such topics.



2008 ◽  
Vol 1 (2) ◽  
pp. 121-128 ◽  
Author(s):  
Kamalesh Sarkar ◽  
Swati Bhattacharya ◽  
Subhasish Bhattacharyya ◽  
Soma Chatterjee ◽  
Aiyel Haque Mallick ◽  
...  


Sexual Health ◽  
2005 ◽  
Vol 2 (2) ◽  
pp. 77 ◽  
Author(s):  
Frieda M-T. Behets ◽  
Kathleen Van Damme ◽  
Andry Rasamindrakotroka ◽  
Marcia Hobbs ◽  
Kristi McClamroch ◽  
...  

Background: Too little is known about the many women who generate income in Madagascar by trading sex. Methods: Clinical and laboratory exams were offered to 493 non-care seeking female sex workers (SWs) in Antananarivo and 493 in Tamatave. SWs were recruited by peers in their community; they were interviewed, counselled and treated for sexually transmitted infections (STIs) at recruitment and re-evaluated 2 months later. Results: One hundred and eighty six (38%) of the SWs in Antananarivo and 113 (23%) in Tamatave did not complete primary school (P < 0.0001). The incidence rates per person per month in Antananarivo and Tamatave, respectively, were 0.09 and 0.08 for gonorrhoea; 0.05 and 0.03 for chlamydia; 0.24 and 0.15 for trichomoniasis; 0.07 and 0.05 for syphilis. At follow-up, consistent condom use with clients was reported by 56 (12%) SWs in Antananarivo and 137 (29%) in Tamatave (P < 0.0001); 320 (70%) SWs in Antananarivo and 11 (2%) in Tamatave reported sex with a non-paying partner in the past month (P < 0.0001). In Antananarivo, 422 (92%) of the SWs thought they were at no or low risk of having an STI compared to 100 (21%) in Tamatave (P = 0.02). At follow-up, 277 (61%) SWs reported no birth control for their last sex act in Antananarivo, compared to 26 (5%) in Tamatave (P < 0.0001). Socio-demographic and behavioural risk factors for incident gonorrhoea, chlamydia and trichomoniasis varied by city. Conclusions: Strategies to address the needs of women who trade sex should include educational and economic opportunities; should tackle male partners of SWs; promote dual protection against unintended pregnancy and STIs, while taking into account local socio-demographic and behavioural characteristics.



2019 ◽  
Vol 4 (2) ◽  
pp. 27-32
Author(s):  
Fatjona Kamberi ◽  
Eva Muhaj

Objective: Human Papilloma Virus (HPV) infection is the most common sexually transmitted among young people of both sexes. It is also the main cause of cervical cancer. This study aimed at assessing students’ knowledge and health beliefs about HPV infection and the use of the vaccine.Methods: The sample of the cross-sectional study was 120 randomly selected nursing students from the Faculty of Public Health, University of Vlore “Ismail Qemali” Albania. Anonymous, self-administered questionnaire based on the literature and Health Belief Model, was used for data collection in May 2017. The questionnaire included assessment questions for students’ knowledge and health beliefs about HPV and vaccine use. Also, questions about socio-demographic characteristics were included. Data analysis included the calculation of averages, frequencies, and confidence intervals. P values ≤0.05 were accepted as statistically significant.Result: Mean age 20.3±2.2 years, 92.44 % of students were female. 65.83% of students know that HPV is a sexually transmitted infection and a vaccine is available to prevent it. Ambiguities and uncertainties exist in regard to screening with Pap test after vaccination. Perceived benefits are high for 50.83% of students. Perceived severity appeared low as only 25% of students agree that they may be affected by HPV. Statistical association, p =0.0347 was found between perceived risk and the year of study. The parents’ role in vaccination against HPV have a strong statistical association, p=0.0058 with the year of study as only 8.33 % of students in the third year agree with the fact that that parents do not allow them to be vaccinated against HPV. Conclusion: The study noted the student’s ambiguity and misconceptions about HPV infection. Low severity and lack of knowledge about the vaccine emphasizes that identifying their current level of knowledge and the main source of information are essential to provide comprehensive and appropriate health education.



e-CliniC ◽  
2014 ◽  
Vol 2 (1) ◽  
Author(s):  
Stella R. Nelwan ◽  
Nurdjannah J. Niode ◽  
Marlyn G. Kapantow

Abstract: Condyloma acuminata, also known as genital warts, is a vegetation of certain types of Human Papilloma Virus(HPV), stalky with bumpy surface. This disease is a sexually transmitted disease, most HPV infections in anogenital area are acquired during sex. This was a descriptive retrospective study, where the data were collected from medical records and registers book of sexually transmitted disease (STD) in Dermatovenereology clinic of Prof. Dr. R. D. Kandou Hospital Manado. The result showed that in 2012, there were 27 new cases of condyloma acuminata, 2.46% of all new patients Most age group found was 25-44 years which was 13 patients (48.15%), with sex distribution mostly found in female patients which was 14 patients (51.85%). Most occupation found was private employees by 10 patients (37.04%). Most affected locations in female patients was vulva and vulva with vagina by 5 patients each of them (35.71%), where as in male patients was penis which was found in 4 patients. The result also showed that HIV was the most comorbid disease found in 3 patients (11.11%). Conclusion: In this study, most condyloma acuminata patients is in 25-44 age group, mostly found in female, most occupation was private employee, most location affected in female were vulva and vulva with vagina, while in male patients was penis, most therapy used was podophyllin. Most comorbid disease was HIV. Keywords: Condyloma acuminata, Human papilloma virus, female    Abstrak: Kondiloma akuminata (KA) adalah vegetasi oleh Human Papilloma Virus (HPV) tipe tertentu, bertangkai dengan permukaannya berjonjot. Penyakit ini tergolong infeksi menular seksual, kebanyakan infeksi HPV di daerah anogenital didapatkan melalui hubungan seksual. Penelitian ini bersifat deskriptif retrospektif; data diambil dari rekam medik dan buku register infeksi menular seksual bagian ilmu penyakit kulit dan kelamin RSU Prof. Dr. R. D. Kandou Manado. Hasil penelitian memperlihatkan pada tahun 2012 dari total kunjungan baru terdapat 27 kasus baru KA (2,46%). Kelompok umur terbanyak didapatkan adalah 25-44 tahun sebanyak 13 orang (48,15%) dengan jenis kelamin terbanyak perempuan sebanyak 14 orang (51,85%) Pada pekerjaan terbanyak pada pekerja swasta sebanyak 10 orang (37,04%) Lokasi lesi pada perempuan tersering di vulva dan vulva ditambah vagina masing-masing sebanyak 5 orang (35,71%), sedangkan pada laki-laki tersering di penis yaitu sebanyak 4 orang. Hasil penelitian juga didapatkan penyakit penyerta terbanyak adalah HIV sebanyak 3 orang (11,11%) . Simpulan: Dalam Penelitian ini, pasien KA terbanyak pada kelompok umur 25-44 tahun paling banyak pada perempuan, jenis pekerjaan pegawai, lokasi lesi pada perempuan tersering pada vulva dan vulva ditambah vagina sedangkan pada laki-laki tersering di penis, pengobatan tersering podofilin. Penyakit penyerta ada lah HIV. Kata kunci: Kondiloma Akuminta, Human papilloma virus, Perempuan.



BMC Urology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
T. Hermans ◽  
R. grosse Siemer ◽  
F. C. von Rundstedt

Abstract Background Ichthyosis is a rare skin disorder, in which the shedding of squamous cells is altered. Intravesical ichthyosis is an extremely rare condition. There is evidence for an association with intravesical condylomata accuminata, caused by urogenital infections of the human papilloma virus. These lesions are generally benign but known to be of a carcinogenic potential and therefore should be treated immediately and followed-up closely. Case presentation We present the case of a 39-year-old woman who presented with recurrent urinary tract infections. During cystoscopy diffuse black pigmented flat bladder tumours were visualized. After transurethral resection the pathological report diagnosed an ichthyosis vesicae. Conclusion We recommend a complete resection with frequent clinical and cystoscopic follow-up. Furthermore, testing for the human papilloma virus should be performed and a vaccination should be offered to the patient. As ichthyosis vesicae is a rare phenomenon, there is an evident lack of clinical data regarding therapy, prognosis and follow-up. With our report, we want to emphasize the need for further research.



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