scholarly journals Cadmium and Lead Toxicity, Modulating Roles of Age and Trace Metals on Wistar Rat Cortical Cells

2015 ◽  
Vol 4 (3) ◽  
Author(s):  
Olugbenga A. Ayannuga ◽  
John A. Oyekunle ◽  
Meashack O. Ijomone ◽  
Blessing I. Ibeachusim
Parasite ◽  
2019 ◽  
Vol 26 ◽  
pp. 12 ◽  
Author(s):  
Zaki M. Al-Hasawi

Studies on host-parasite systems as bioindicators for monitoring trace metal pollution in marine environments are still scarce. Here, 11, 14 and 17 infrapopulations of Gyliauchen volubilis (Trematoda: Digenea), Procamallanus elatensis (Nematoda) and Sclerocollum rubrimaris (Acanthocephala), respectively, were collected from the fish Siganus rivulatus (Siganidae) in the Red Sea, from a chronically polluted small bay at Sharm El-Sheikh, South Sinai, Egypt. Water and sediment samples from the bay, tissue samples (intestines, liver, and muscle) from each fish, and samples from each parasite were taken for heavy metal analyses of cadmium and lead. Cadmium concentrations in intestines, liver and muscle of non-infected and infected fishes were much lower than those of lead, and both metal concentrations decreased in the order: liver > intestines > muscle. Cadmium and lead concentrations in the tissues of fishes infected with G. volubilis or P. elatensis were slightly lower than those in non-infected ones, while in the tissues of fishes infected with Sc. rubrimaris, they were much lower. Low concentrations of cadmium and lead in G. volubilis and P. elatensis are associated with their limited ability or capacity to accumulate trace metals. Therefore, bioconcentration factors corresponding to these species were relatively low, and both are herein considered as weak bioindicators. By contrast, high concentrations of cadmium and lead in S. rubrimaris are associated with its high ability to accumulate trace metals. Of the present three host–parasite systems, only the Siganus rivulatus–Sclerocollum rubrimaris system seems to be promising for biomonitoring of metal pollution in the Red Sea.


2020 ◽  
Vol 145 ◽  
pp. 106122
Author(s):  
Lin Tang ◽  
Yasir Hamid ◽  
Di Liu ◽  
Md. Jahidul Islam Shohag ◽  
Afsheen Zehra ◽  
...  

Author(s):  
G. N. Okechukwu ◽  
E. Ezor ◽  
E. Finbarrs-Bello ◽  
L. N. Ebube ◽  
G. C. Uzomba ◽  
...  

Lead is a heavy metal found in earth’s crust. It is a widespread and insidious environmental toxin known as a severe and aggressive contaminant to human and animal organisms’ health status. This work is aimed at evaluating the effect of aqueous extract of Ocimum gratissimum (OG) on lead induced changes in the thymus of adult albino wistar rats. Thirty five male Wistar rats were used in the study and were randomly divided into seven groups with five rats in each group. The rats in Group one (G1) served as the Control and received distilled water. Group 2 received 120 mg/kg body weight (bwt) of lead acetate, G3 received 375 mg/kg bwt of OG only. G4 received 120 mg/kg bwt of lead acetate and OG extract at 375 mg/kg bwt., G5 received 120 mg/kg bwt of lead and OG at 750 mg/kg bwt. G6 received 375 mg/kg bwt of OG in two weeks followed by 120 mg/kg bwt of lead acetate for one week, while G7 received 120 mg/kg bwt of lead acetate and Vitamin C at 11900 mg/kg. All the administrations were carried out orally for twenty one (21) days. At the end of the administration, the rats were fasted for 24 hours. They weighted and humanely sacrificed via cervical dislocation. The thymus were harvested in all the groups and prepared for histological studies using routine haematoxylin and eosin (H&E) staining techniques. The result of the present study shows that lead possessed a distortive effect in the histoarchitecture of thymus of the wistar rat in G2 when compared with G1. Treatment of these experimental animals with vitamin C prove to posses more ameliorative effect in restoring the histoarchitecture on lead toxicity in the thymus closed to normal than OG. Therefore, it is suggested that aqueous extract OG can act via the same pathway as vitamin C, in maintaining the normal histological structures of the thymus of adult albino wistar rat exposed to lead toxicity.


1979 ◽  
Vol 205 (1158) ◽  
pp. 135-143 ◽  

Cardiovascular disease is a major cause of morbidity and mortality in the U. K. and other developed countries. In the U. K., mortality from coronary heart disease has increased progressively over the past 25 years, particularly in males. This paper examines the possible role of trace metals in the development of cardiovascular disease, with particular reference to the effects of cobalt, cadmium and lead in myocardial disease, atherosclerosis and hypertension. It is concluded that cobalt is an unimportant factor in community levels of cardiovascular disease, that cadmium has striking effects on blood pressure in animals and that there is some evidence for an association between environmental lead and high blood pressure.


1974 ◽  
Vol 28 (4) ◽  
pp. 342-344 ◽  
Author(s):  
M. S. Vigler ◽  
V. F. Gaylor

To provide information for customers who have regional environmental obligations, it was necessary to develop an analytical procedure to analyze for 25 metals in the range from 1 ppb to greater than 5 ppm in petroleum products. Atomic absorption is employed to determine 23 of the elements, namely: Al, Sb, Ba, Be, Bi, Ca, Cd, Co, Cr, Cu, Fe, K, Pb, Mg, Mn, Mo, Ni, Na, Si, Sn, Ti, V, and Zn. The general procedure is to ash the appropriate amount of sample by absorbing liquid samples on magnesium sulfonate ash aid (Conostan, Conoash M) or potassium sulfonate. Add 5 drops of H2SO4, heat to white fumes, fire, and ash at 650°C. The sulfonated ash is dissolved in dilute acid to provide the aspiration solution. Recovery studies on aluminum, antimony, beryllium, cadmium, and lead in the microgram per gram range are presented.


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