scholarly journals Surgical site infection in adults undergoing major non-cardiac surgery and its association with anemia, severe bleeding and intraoperative transfusion: A preliminary report from a prospective registry

2020 ◽  
Vol 48 (4) ◽  
Author(s):  
Fredy Ariza ◽  
Darío Alberto Castaño ◽  
Julián David Bolaños-Aldana ◽  
Manuel Quintana-Díaz
Keyword(s):  
Risk Factors ◽  
Cardiac Surgery ◽  
Surgical Site Infection ◽  
Multiple Organ ◽  
Adult Patients ◽  
Major Surgery ◽  
Severe Bleeding ◽  
Site Infection ◽  
Factors Associated ◽  
Preoperative Hemoglobin

Introduction Surgical site infection (SSI) is among the most common healthcare-related infections. Given their greater morbidity and surgical complexity, patients undergoing major surgery are exposed to a high risk of SSI. Objective To determine the incidence of SSI in adult patients undergoing major elective non-cardiac surgery, and to identify risk factors associated with its occurrence within the first 30 days after surgery. Methods An analytical study was designed on the basis of a prospective institutional registry. Clinical and laboratory variables associated with perioperative management were recorded. An active search was conducted in order to find SSI episodes, renal failure and multiple organ dysfunction during the first 30 days after surgery. Adjusted logistic regression was done to identify potential associations between risk factors and the development of SSI. Results Overall, 1501 patients were included. The incidence of SSI during the first 30 days after surgery was 6.72% (95% CI 5.57-8.11). ASA III, abdominal surgery and longer procedures were more frequent in the SSI group. Association with the occurrence of SSI was documented for preoperative hemoglobin levels (adjusted OR 0.79 [95% CI 0.72-0.88], p = 0.04), intraoperative transfusion (adjusted OR 2,47 [95% CI 1.16-5.27], p = 0.02) and major blood loss (adjusted OR 3.80 [95% CI 1.63-8.88], p = 0.04). Conclusion Preoperative hemoglobin level, intraoperative transfusion and major bleeding are independent risk factors associated with the occurrence of SSI in adult patients undergoing major elective non-cardiac surgery.

Risk Factors Associated with Surgical Site Infection in Pediatric Patients Undergoing Spinal Deformity Surgery

JBJS Reviews ◽  
2020 ◽  
Vol 8 (3) ◽  
pp. e0163
Author(s):  
Hiroko Matsumoto ◽  
Matthew E. Simhon ◽  
Megan L. Campbell ◽  
Michael G. Vitale ◽  
Elaine L. Larson
Keyword(s):  
Risk Factors ◽  
Surgical Site Infection ◽  
Spinal Deformity ◽  
Pediatric Patients ◽  
Site Infection ◽  
Factors Associated ◽  
Spinal Deformity Surgery

Surgical Site Infection During Hospitalization and After Discharge in Patients Who Have Undergone Cardiac Surgery

2006 ◽  
Vol 27 (1) ◽  
pp. 85-88 ◽  
Author(s):  
Marta Fernández-Ayala ◽  
Daniel N. Nan ◽  
Concepción Farinas-Álvarez ◽  
José M. Revuelta ◽  
Jesús González-Macías ◽  
...  
Keyword(s):  
Risk Factors ◽  
Multivariate Analysis ◽  
Cardiac Surgery ◽  
Surgical Site Infection ◽  
Hospital Discharge ◽  
Site Infection

During a 13-month period, 513 patients who were scheduled to undergo cardiac surgery were prospectively observed for surgical site infection during hospitalization after surgery and for 1 month after hospital discharge. Fifty-three patients showed evidence of surgical site infection (during hospitalization for 31 patients and after discharge for 22). Multivariate analysis identified that risk factors for surgical site infection differed between infections that occurred during hospitalization and those that occurred after discharge.

scholarly journals Risk factors for surgical site infection in cardiac surgery

2012 ◽  
Vol 25 (spe2) ◽  
pp. 89-95 ◽  
Author(s):  
Quenia Cristina Gonçalves da Silva ◽  
Maria Helena Barbosa
Keyword(s):  
Social Sciences ◽  
Risk Factors ◽  
Cardiac Surgery ◽  
Surgical Site Infection ◽  
Descriptive Analysis ◽  
Male Gender ◽  
Site Infection ◽  
Measures Of Association ◽  
Historical Cohort ◽  
The Social

OBJECTIVE: To analyze the occurrence of surgical site infection (SSI) in patients undergoing cardiac surgery in the period between July 2005, and July 2010. METHODS: A quantitative, historical cohort study that evaluated 384 patients in a public teaching hospital. The Statistical Package for the Social Sciences software was used for data analysis and for descriptive analysis, measures of association in contigency tables and logistic regression were used. RESULTS: It was found that 36 (9.4%) patients developed a SSI and that mortality occurred in 14 (38.9%). Staphylococcus aureus was the prevalent microorganism (12, 27.3%) In the multivariate analysis, the risk factors identified as predictors of SSI were male gender, intubation for more than 24 hours, and reintubation. CONCLUSION: The risk factors predictive of the occurence of SSI (p<0.05) were: male gender, reintubation, and intubation for more than 24 hours.

Epidemiological Surveillance of Surgical Site Infection and its Risk Factors in Cardiac Surgery: A Prospective Cohort Study

2016 ◽  
Vol 69 (9) ◽  
pp. 842-848
Author(s):  
Angels Figuerola-Tejerina ◽  
Gil Rodríguez-Caravaca ◽  
Juan Bustamante-Munguira ◽  
Jesús María San Román-Montero ◽  
Manuel Durán-Poveda
Keyword(s):  
Risk Factors ◽  
Cardiac Surgery ◽  
Cohort Study ◽  
Surgical Site Infection ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Epidemiological Surveillance ◽  
Site Infection

scholarly journals Risk Factors Associated With Surgical Site Infection After Pediatric Posterior Spinal Fusion Procedure

2009 ◽  
Vol 30 (2) ◽  
pp. 109-116 ◽  
Author(s):  
W. Matthew Linam ◽  
Peter A. Margolis ◽  
Mary Allen Staat ◽  
Maria T. Britto ◽  
Richard Hornung ◽  
...  
Keyword(s):  
Risk Factors ◽  
Surgical Site Infection ◽  
Antibiotic Prophylaxis ◽  
Spinal Fusion ◽  
Univariate Analysis ◽  
Posterior Spinal Fusion ◽  
Site Infection ◽  
Fusion Procedure ◽  
Factors Associated ◽  
Asa Score

Objective.To identify risk factors associated with surgical site infection (SSI) after pediatric posterior spinal fusion procedure by examining characteristics related to the patient, the surgical procedure, and tissue hypoxia.Design.Retrospective case-control study nested in a hospital cohort study.Setting.A 475-bed, tertiary care children's hospital.Methods.All patients who underwent a spinal fusion procedure during the period from January 1995 through December 2006 were included. SSI cases were identified by means of prospective surveillance using National Nosocomial Infection Surveillance system definitions. Forty-four case patients who underwent a posterior spinal fusion procedure and developed an SSI were identified and evaluated. Each case patient was matched (on the basis of date of surgery, ± 3 months) to 3 control patients who underwent a posterior spinal fusion procedure but did not develop an SSI. Risk factors for SSI were evaluated by univariate analysis and multivariable conditional logistic regression. Odds ratios (ORs), with 95% confidence intervals (CIs) andPvalues, were calculated.Results.From 1995 to 2006, the mean annual rate of SSI after posterior spinal fusion procedure was 4.4% (range, 1.1%—6.7%). Significant risk factors associated with SSI in the univariate analysis included the following: a body mass index (BMI) greater than the 95th percentile (OR, 3.5 [95% CI, 1.5–8.3]); antibiotic prophylaxis with clindamycin, compared with other antibiotics (OR, 3.5 [95% CI, 1.2 10.0]); inappropriately low dose of antibiotic (OR, 2.6 [95% CI, 1.0–6.6]); and a longer duration of hypothermia (ie, a core body temperature of less than 35.5°C) during surgery (OR, 0.4 [95% CI, 0.2–0.9]). An American Society of Anesthesiologists (ASA) score of greater than 2, obesity (ie, a BMI greater than the 95th percentile), antibiotic prophylaxis with clindamycin, and hypothermia were statistically significant in the multivariable model.Conclusion.An ASA score greater than 2, obesity, and antibiotic prophylaxis with clindamycin were independent risk factors for SSI. Hypothermia during surgery appears to provide protection against SSI in this patient population.

Risk factors associated with surgical site infection in upper and lower gastrointestinal surgery

Surgery Today ◽  
2008 ◽  
Vol 38 (5) ◽  
pp. 404-412 ◽  
Author(s):  
Akihiro Watanabe ◽  
Shunji Kohnoe ◽  
Rinshun Shimabukuro ◽  
Takeharu Yamanaka ◽  
Yasunori Iso ◽  
...  
Keyword(s):  
Risk Factors ◽  
Surgical Site Infection ◽  
Gastrointestinal Surgery ◽  
Site Infection ◽  
Factors Associated

scholarly journals Risk factors for surgical site infection in cardiac surgery – A short literary survey, risk patterns

2014 ◽  
Vol 20 (1-2) ◽  
pp. 11
Author(s):  
Pavlin Manoilov ◽  
Plamen Panayotov ◽  
Hristofor Cherkezov ◽  
Alexander Georgiev
Keyword(s):  
Risk Factors ◽  
Cardiac Surgery ◽  
Surgical Site Infection ◽  
Site Infection

Risk Factors for the Development of Nosocomial Pneumonia and Its Clinical Impact in Cardiac Surgery

2021 ◽  
Author(s):  
Ferdinand Jr Rivera Gerod ◽  
Edgar Ongjoco ◽  
Rod Castro ◽  
Armin Masbang ◽  
Elmer Casley Repotente ◽  
...  
Keyword(s):  
Risk Factors ◽  
Mechanical Ventilation ◽  
Cardiac Surgery ◽  
Hospital Mortality ◽  
Nosocomial Pneumonia ◽  
Clinical Impact ◽  
Adult Patients ◽  
Mortality And Morbidity ◽  
Factors Associated ◽  
Prolonged Icu Stay

Abstract BackgroundThe development of nosocomial pneumonia after cardiac surgery is a significant post-operative complication that may lead to increased morbidity, mortality, and hospital cost. We aimed to identify risk factors associated with it and to determine its clinical impact in terms of in-hospital mortality and morbidity.MethodsThis is a retrospective cohort study conducted among all adult patients who underwent cardiac surgery from 2014-2019 in St. Luke’s Medical Center, Quezon City, Philippines. Baseline characteristics and possible risk factors for pneumonia were retrieved from medical records. Nosocomial pneumonia was based on the Centers for Disease Control and Prevention criteria. Clinical outcomes include in-hospital mortality and morbidity. Odds ratios from logistic regression was computed to determine risk factors associated with pneumonia using STATA 15.0.ResultsOut of 373 patients included in this study, 104 (28%) patients acquired pneumonia. Most surgeries were coronary artery bypass graft (CABG) (71.58%), followed by valve repair/replacement (29.76%). Neither age, sex, BMI, diabetes, LV dysfunction, renal dysfunction, COPD/asthma, urgency of surgery, surgical time, nor smoking showed association in the development of pneumonia. However, preoperative stay of >2 days was associated with 92.3% (95%CI 18–213%) increased odds of having pneumonia (p=.009). Also, every additional hour on mechanical ventilation conferred 0.8% (95%CI, 0.3–1%) greater odds of acquiring pneumonia (p=.003).Patients who developed pneumonia had 3.9 times odds of mortality (95%CI 1.51–9.89, p=.005), 3.8 times odds of prolonged hospitalization (95%CI 1.81–7.90,p<.001), 6.4 times odds of prolonged ICU stay (95%CI 3.59–11.35,p<.001), and 9.5 times odds of postoperative reintubation (95%CI 3.01–29.76,p<.001). ConclusionAmong adult patients undergoing cardiac surgeries, prolonged preoperative hospital stay and prolonged mechanical ventilation were both associated with an increased risk for nosocomial pneumonia. Those who developed pneumonia had worse outcomes with significantly increased in-hospital mortality, prolonged hospitalization, prolonged ICU stay, and increased postoperative re-intubation. Clinicians should therefore minimize delays in surgery to avoid unnecessary exposure to pathogenic organisms. Also, timely liberation from mechanical ventilation after surgery should be encouraged.

scholarly journals Risk Factors for Methicillin-ResistantStaphylococcus aureusSurgical Site Infection

2008 ◽  
Vol 29 (9) ◽  
pp. 890-893 ◽  
Author(s):  
Stephan Harbarth ◽  
Benedikt Huttner ◽  
Pascal Gervaz ◽  
Carolina Fankhauser ◽  
Marie-Noelle Chraiti ◽  
...  
Keyword(s):  
Risk Factors ◽  
Staphylococcus Aureus ◽  
Surgical Site Infection ◽  
Immunosuppressive Therapy ◽  
Emergency Surgery ◽  
Intervention Study ◽  
Comorbid Condition ◽  
Site Infection ◽  
Factors Associated ◽  
Surgical Duration

We prospectively evaluated 46 possible risk factors for methicillin-resistantStaphylococcus aureus(MRSA) surgical site infection (SSI) among patients with MRSA carriage in a large intervention study. Of 6,130 study patients, 68 (1.1%) developed MRSA SSI, which occurred a median of 14 days after surgery. Risk factors associated with MRSA SSI were receipt of emergency surgery, presence of comorbid condition, receipt of immunosuppressive therapy, receipt of contaminated surgery, and a surgical duration longer than the 75th percentile. MRSA carriage on admission did not predict MRSA SSI.

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