scholarly journals The effect of sodium hyaluronatecarboxymethyl cellulose membrane in the prevention of parenchymal air leaks: an experimental and manometric study in rats

2017 ◽  
Vol 65 (4) ◽  
pp. 265-270 ◽  
Author(s):  
Songül Büyükkale ◽  
Necati Çıtak ◽  
Özgür İşgörücü ◽  
Adnan Sayar
Keyword(s):  
Cellulose Membrane ◽  
Air Leaks ◽  
Manometric Study

Porous SBA-15/cellulose membrane with prolonged anti-microbial drug release characteristics for potential wound dressing application

Cellulose ◽  
2020 ◽  
Vol 27 (5) ◽  
pp. 2737-2756
Author(s):  
Zhi Shen ◽  
Ning Cai ◽  
Yanan Xue ◽  
Bo Yu ◽  
Jianzhi Wang ◽  
...  
Keyword(s):  
Drug Release ◽  
Wound Dressing ◽  
Cellulose Membrane

Development of a new analytical approach based on cellulose membrane and chelator for differentiation of labile and inert metal species in aquatic systems

2006 ◽  
Vol 567 (2) ◽  
pp. 152-159 ◽  
Author(s):  
André Henrique Rosa ◽  
Iramaia C. Bellin ◽  
Danielle Goveia ◽  
Luciana C. Oliveira ◽  
Roberto W. Lourenço ◽  
...  
Keyword(s):  
Analytical Approach ◽  
Aquatic Systems ◽  
Metal Species ◽  
Cellulose Membrane

scholarly journals Bio-artificial pleura using autologous dermal fibroblast sheets to mitigate air leaks during thoracoscopic lung resection

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Masato Kanzaki ◽  
Ryo Takagi ◽  
Kaoru Washio ◽  
Mami Kokubo ◽  
Shota Mitsuboshi ◽  
...  
Keyword(s):  
Dermal Fibroblast ◽  
Lung Resection ◽  
Fibroblast Cell ◽  
Patient Specific ◽  
Cell Content ◽  
Cell Monolayers ◽  
Air Leaks ◽  
Skin Biopsies ◽  
Dermal Cells ◽  
Lung Resections

AbstractLung air leaks (LALs) due to visceral pleura injury during surgery are a difficult-to-avoid complication in thoracic surgery (TS). Reliable LAL closure is an important patient management issue after TS. We demonstrated both safeties of transplantation of a cultured human autologous dermal fibroblast sheet (DFS) to LALs. From May 2016 to March 2018, five patients who underwent thoracoscopic lung resection met all the inclusion criteria. Skin biopsies were acquired from each patient to source autologous dermal cells for DFS fabrication. During the primary culture, fibroblasts migrated from the dermal tissue pieces and proliferated to form cell monolayers. These fibroblasts were subcultured to confluence. Transplantable DFSs were fabricated from these subcultured fibroblasts that were trypsinized and seeded onto temperature-responsive culture dishes. After 10 days of fabrication culture, intact patient-specific DFS were harvested. DFSs were analyzed for fibroblast cell content and tissue contaminants prior to application. For closing intraoperative LAL, mean number of transplanted autologous DFS per patient was 6 ± 2 sheets. Mean chest drainage duration was 5.0 ± 4.8 days. The two patients with major LAL had a drainage duration of more than 7 days. All patients currently have no LAL recurrence after discharge. DFSs effectively maintain LAL closure via remodeling of the deposited extracellular matrix. The use of autologous DFSs to permanently close air leaks using a patient-derived source is expected to reduce surgical complications during high-risk lung resections.

scholarly journals Synthesis and Characterization of a Fullerenol Derivative for Potential Biological Applications

2020 ◽  
Vol 4 (1) ◽  
pp. 15
Author(s):  
Eduardo Ravelo-Nieto ◽  
Alvaro Duarte-Ruiz ◽  
Luis H. Reyes ◽  
Juan C. Cruz
Keyword(s):  
Phase Transfer ◽  
Protein A ◽  
Structural Features ◽  
Cellular Level ◽  
Cellulose Membrane ◽  
Cell Penetration ◽  
Covalent Functionalization ◽  
Dialysis Tubing ◽  
Surface Functionality

Several biological barriers are generally responsible for the limited delivery of cargoes at the cellular level. Fullerenols have unique structural features and possess suitable properties for interaction with the cells. This study aimed to synthesize and characterize a fullerenol derivative with desirable characteristics (size, charge, functionality) to develop cell penetration vehicles. Fullerenol was synthesized from fullerene (C60) solubilized in toluene, followed by hydroxylation with hydrogen peroxide and tetra-n-butylammonium hydroxide (TBAH) as a phase transfer catalyst. The obtained product was purified by a Florisil chromatography column (water as the eluent), followed by dialysis (cellulose membrane dialysis tubing) and freeze-drying (yield 66%). Subsequently, a silane coupling agent was conjugated on the fullerenol surface to render free amine functional groups for further covalent functionalization with other molecules. Characterization via UV–VIS, FTIR-ATR, Raman, DLS, and SEM techniques was conducted to evaluate the composition, size, morphology, surface functionality, and structural properties. We are currently working on the conjugation of the potent cell-penetrating agents Buforin II (BUFII) and the Outer Membrane Protein A (OmpA) on the surface of the fullerenol to estimate whether cell penetration and endosome escape are improved concerning conventional polymeric vehicles and our previous developments with iron oxide nanoparticles.

scholarly journals Bacterial Cellulose Membrane Containing Epilobium angustifolium L. Extract as a Promising Material for the Topical Delivery of Antioxidants to the Skin

2021 ◽  
Vol 22 (12) ◽  
pp. 6269
Author(s):  
Anna Nowak ◽  
Paula Ossowicz-Rupniewska ◽  
Rafał Rakoczy ◽  
Maciej Konopacki ◽  
Magdalena Perużyńska ◽  
...  
Keyword(s):  
Bacterial Cellulose ◽  
Topical Application ◽  
Phenolic Acid ◽  
Antioxidant Properties ◽  
Ethanolic Extract ◽  
Cellulose Membrane ◽  
Hydroxybenzoic Acid ◽  
Epilobium Angustifolium ◽  
Bacterial Cellulose Membrane

Bacterial cellulose membranes (BCs) are becoming useful as a drug delivery system to the skin. However, there are very few reports on their application of plant substances to the skin. Komagataeibacter xylinus was used for the production of bacterial cellulose (BC). The BC containing 5% and 10% ethanolic extract of Epilobium angustifolium (FEE) (BC-5%FEE and BC-10%FEE, respectively) were prepared. Their mechanical, structural, and antioxidant properties, as well as phenolic acid content, were evaluated. The bioavailability of BC-FESs using mouse L929 fibroblasts as model cells was tested. Moreover, in vitro penetration through the pigskin of the selected phenolic acids contained in FEE and their accumulation in the skin after topical application of BC-FEEs was examined. The BC-FEEs were characterized by antioxidant activity. The BC-5% FEE showed relatively low toxicity to healthy mouse fibroblasts. Gallic acid (GA), chlorogenic acid (ChA), 3,4-dihydroxybenzoic acid (3,4-DHB), 4-hydroxybenzoic acid (4-HB), 3-hydroxybenzoic acid (3-HB), and caffeic acid (CA) found in FEE were also identified in the membranes. After topical application of the membranes to the pigskin penetration of some phenolic acid and other antioxidants through the skin as well as their accumulation in the skin was observed. The bacterial cellulose membrane loaded by plant extract may be an interesting solution for topical antioxidant delivery to the skin.

A graphene oxide facilitated a highly porous and effective antibacterial regenerated cellulose membrane containing stabilized silver nanoparticles

Cellulose ◽  
2014 ◽  
Vol 21 (6) ◽  
pp. 4261-4270 ◽  
Author(s):  
Soon Wei Chook ◽  
Chin Hua Chia ◽  
Sarani Zakaria ◽  
Mohd Khan Ayob ◽  
Nay Ming Huang ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Graphene Oxide ◽  
Regenerated Cellulose ◽  
Cellulose Membrane ◽  
Highly Porous

Management of Persistent Air Leaks with Intrabronchial Valves

2017 ◽  
Vol 66 (07) ◽  
pp. 603-606
Author(s):  
Andreas Hecker ◽  
Konstantin Mayer ◽  
Biruta Witte ◽  
Matthias Hecker
Keyword(s):  
Thoracic Surgery ◽  
Minimal Invasive ◽  
Therapeutic Approaches ◽  
Air Leak ◽  
Frequent Complication ◽  
Less Invasive ◽  
Air Leaks ◽  
Prolonged Hospitalization ◽  
Highly Effective ◽  
Endoscopic Placement

AbstractPersistent air leaks (PALs) are regarded as a frequent complication after thoracic surgery resulting in prolonged hospitalization and increased morbidity. Several more or less invasive therapeutic approaches are available for treatment of PAL with varying degrees of success. The endoscopic placement of one-way intrabronchial valves in the segment(s) in which the air leak has been located offers a highly effective and well-tolerated minimal invasive option for patients with PAL.

Superhydrophobic PVDF/micro fibrillated cellulose membrane for membrane distillation crystallization of struvite

2021 ◽  
Author(s):  
Hoi-Fang Tan ◽  
Why-Ling Tan ◽  
B.S. Ooi ◽  
C.P. Leo
Keyword(s):  
Membrane Distillation ◽  
Cellulose Membrane
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