Role of Palatal Rugae in Forensic Identification of the Pediatric Population

10.5580/1e67 ◽  
2010 ◽  
Vol 4 (2) ◽  
2022 ◽  
Vol 23 (2) ◽  
pp. 870
Author(s):  
Anna Kawalec ◽  
Danuta Zwolińska

The microbiome of the urinary tract plays a significant role in maintaining health through the impact on bladder homeostasis. Urobiome is of great importance in maintaining the urothelial integrity and preventing urinary tract infection (UTI), as well as promoting local immune function. Dysbiosis in this area has been linked to an increased risk of UTIs, nephrolithiasis, and dysfunction of the lower urinary tract. However, the number of studies in the pediatric population is limited, thus the characteristic of the urobiome in children, its role in a child’s health, and pediatric urologic diseases are not completely understood. This review aims to characterize the healthy urobiome in children, the role of dysbiosis in urinary tract infection, and to summarize the strategies to modification and reshape disease-prone microbiomes in pediatric patients with recurrent urinary tract infections.


CJEM ◽  
2008 ◽  
Vol 10 (01) ◽  
pp. 38-43 ◽  
Author(s):  
Kathleen Brown ◽  
Sharon E. Mace ◽  
Ann M. Dietrich ◽  
Stephen Knazik ◽  
Neil E. Schamban

ABSTRACT Patient and family–centred care (PFCC) is an approach to health care that recognizes the integral role of the family and encourages mutually beneficial collaboration between the patient, family and health care professionals. Specific to the pediatric population, the literature indicates that the majority of families wish to be present for all aspects of their child's care and be involved in medical decision-making. Families who are provided with PFCC are more satisfied with their care. Integration of these processes is an essential component of quality care. This article reviews the principles of PFCC and their applicability to the pediatric patient in the emergency department; and it discusses a model for integrating PFCC that is modifiable based on existing resources.


2000 ◽  
Vol 34 (5) ◽  
pp. 630-638 ◽  
Author(s):  
Jackie Y Raskind ◽  
Gladys M El-Chaar

OBJECTIVE: To review the pathophysiology and significance of valproic acid–induced carnitine deficiency; to present and evaluate the literature pertaining to carnitine supplementation in pediatric patients receiving valproic acid; and to present the consensus guidelines for carnitine supplementation during valproic acid therapy. DATA SOURCES: A MEDLINE search (1966–December 1998) restricted to English-language literature, using MeSH headings of carnitine and valproic acid, was conducted to identify clinically relevant articles. Selected articles and references focusing on the pediatric population were included for review. DATA EXTRACTION: Study design, patient population, methods, and clinical outcomes were evaluated. DATA SYNTHESIS: Valproic acid, a widely used antiepileptic agent in the pediatric population, is limited by a 1/800 incidence of fatal hepatotoxicity in children under the age of two years. Carnitine is an essential amino acid necessary in β-oxidation of fatty acids and energy production in cellular mitochondria. It has been hypothesized that valproic acid may induce a carnitine deficiency in children and cause nonspecific symptoms of deficiency, hepatotoxicity, and hyperammonemia. Relevant published case reports and trials studying this relationship are evaluated, and a consensus statement by the Pediatric Neurology Advisory Committee is reviewed. CONCLUSIONS: Despite the lack of prospective, randomized clinical trials documenting efficacy of carnitine supplementation in preventing valproic acid–induced hepatotoxicity, the few limited studies available have shown carnitine supplementation to result in subjective and objective improvements along with increases in carnitine serum concentrations in patients receiving valproic acid. The Pediatric Neurology Advisory Committee in 1996 provided more concrete indications on the role of carnitine in valproic acid therapy, such as valproic acid overdose and valproic acid–induced hepatotoxicity. Carnitine was strongly recommended for children at risk of developing a carnitine deficiency. Although carnitine has been well tolerated, future studies are needed to evaluate the efficacy of prophylactic carnitine supplementation for the prevention of hepatotoxicity.


2019 ◽  
Vol 161 (4) ◽  
pp. 683-687 ◽  
Author(s):  
Gerard Thong ◽  
Natasha D. Dombrowski ◽  
Kosuke Kawai ◽  
Michael J. Cunningham ◽  
Eelam A. Adil

Objective Balloon sinuplasty (BS) is a surgical management option in the treatment of chronic rhinosinusitis. The purpose of this study was to examine BS utilization among children with a national database. Study Design Retrospective review. Setting National pediatric database. Subjects and Methods All cases of children aged ≤18 years who underwent BS or traditional endoscopic sinus surgery (ESS) 5 years before and after the introduction of BS billing codes were studied with the Pediatric Health Information System database. We evaluated overall trends, demographics, performing physicians, readmissions, and cost data. Results A total of 14,079 patients met inclusion criteria: 13,555 underwent traditional ESS and 524 had a BS procedure. There was no significant increase in BS rates between 2011 and 2016. BS was more commonly performed among younger children than ESS (median age [interquartile range], 6 years [4-10] vs 9 years [6-13]; P < .001). There were 23 (4.4%) readmissions within 30 days in the balloon cohort versus 474 (3.5%) in the ESS cohort. The median cost of balloon maxillary antrostomy (US $6560 [$5420-$8250]) was higher than that of traditional maxillary antrostomy (US $5630 [$4130-$7700], P < .001). Physicians who performed BS had a larger volume of ESS procedures when compared with those who did not perform BS. Conclusion Rates of BS performance in the pediatric population have not increased over time. Results showed no difference in readmission rates between BS and ESS. BS was associated with higher costs as compared with ESS. The role of BS in the pediatric chronic rhinosinusitis population remains unclear.


2019 ◽  
Vol 43 (2) ◽  
pp. 63-68
Author(s):  
Tam T. T. Huynh ◽  
B. N. Garza ◽  
J. Geer ◽  
K. C. Broadbent ◽  
W. A. Martinek ◽  
...  

The autogenous arteriovenous fistula (AVF) is the preferred vascular access for pediatric and adult patients on chronic hemodialysis (HD). However, the prevalent rate of AVF use in children remains low in the United States. Duplex ultrasonography (DUS) of arm vessels is an essential step in the planning of AVF creation in adults, but its use in children is not described in much detail. In this retrospective study, we examined the role of preoperative DUS in children and adolescents who underwent AVF creation at a single large pediatric hospital, from 2008 to 2017. In addition, we sought to determine the potential risk factors for primary failure (PF), which was defined as the inability to use the AVF for at least a sustained 6-week period either due to thrombosis or any other reasons. We created 67 AVFs in 57 patients (34 male; 60%). The overall PF was 16% (11/67), and higher in cephalic AVF (10/40, 25%) compared to basilic (1/27, 3.7%), P = .04. The median maturation time was longer for basilic compared to cephalic AVF (105±47 vs. 88±38 days, respectively, P = .006). The size of the juxta-anastomotic vein and artery on preoperative DUS was not significantly different in cephalic versus basilic AVFs. However, the median diameter of the outflow vein was significantly smaller in the cephalic compared to basilic AVF (3.4 mm vs. 4.2 mm, P = .042). In addition, the outflow vein size was the only preoperative factor found to be significant as possible predictor for PF on univariable analysis. The results of this study show that the PF rate and maturation time for AVFs created in children and adolescents are comparable to adults, with the routine use of preoperative DUS. We postulate that vessel selection for AVF in the pediatric population should take into consideration the size of the vein at the outflow (and not just at the anastomosis).


2012 ◽  
Vol 22 (8) ◽  
pp. 781-786 ◽  
Author(s):  
Christoph Schramm ◽  
Jana Knop ◽  
Katrin Jensen ◽  
Konstanze Plaschke

2016 ◽  
Vol 34 (2) ◽  
pp. 510-513
Author(s):  
Xiu-Ping Wu ◽  
Jian-Ning Han ◽  
Pan Fen ◽  
Yu-Jin Wang ◽  
Li Bing

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Panagiota Karananou ◽  
Despoina Tramma ◽  
Socrates Katafigiotis ◽  
Anastasia Alataki ◽  
Alexandros Lambropoulos ◽  
...  

Urinary tract infections are one of the most common and serious bacterial infections in a pediatric population. So far, they have mainly been related to age, gender, ethnicity, socioeconomic level, and the presence of underlying anatomical or functional, congenital, or acquired abnormalities. Recently, both innate and adaptive immunities and their interaction in the pathogenesis and the development of UTIs have been studied. The aim of this study was to assess the role and the effect of the two most frequent polymorphisms of TLR4 Asp299Gly and Thr399Ile on the development of UTIs in infants and children of Greek origin. We studied 51 infants and children with at least one episode of acute urinary tract infection and 109 healthy infants and children. We found that 27.5% of patients and 8.26% of healthy children carried the heterozygote genotype for TLR4 Asp299Gly. TLR4 Thr399Ile polymorphism was found to be higher in healthy children and lower in the patient group. No homozygosity for both studied polymorphisms was detected in our patients. In the group of healthy children, a homozygote genotype for TLR4 Asp299Gly (G/G) as well as for TLR4 Thr399Ile (T/T) was showed (1.84% and 0.92 respectively). These results indicate the role of TLR4 polymorphism as a genetic risk for the development of UTIs in infants and children of Greek origin.


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