scholarly journals Diagnostic and prognostic micro-RNAs in ischaemic stroke due to carotid artery stenosis and in acute coronary syndrome: a four-year prospective study

2017 ◽  
pp. 362-369 ◽  
Author(s):  
Jacek Gacoń ◽  
Rafał Badacz ◽  
Ewa Stępień ◽  
Izabela Karch ◽  
Francisco J. Enguita ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Carotid Artery ◽  
Prospective Study ◽  
Ischaemic Stroke ◽  
Carotid Artery Stenosis ◽  
Artery Stenosis ◽  
Coronary Syndrome ◽  
Micro Rnas

scholarly journals Ficolin-2 serum levels predict the occurrence of acute coronary syndrome in patients with severe carotid artery stenosis

2021 ◽  
Vol 166 ◽  
pp. 105462
Author(s):  
Federico Carbone ◽  
Alessia Valente ◽  
Carlo Perego ◽  
Maria Bertolotto ◽  
Bianca Pane ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Carotid Artery ◽  
Carotid Artery Stenosis ◽  
Serum Levels ◽  
Artery Stenosis ◽  
Coronary Syndrome

scholarly journals A study on prevalence of carotid artery stenosis in acute ischaemic stroke patients in Amalapuram, Andhra Pradesh, India

2019 ◽  
Vol 7 (6) ◽  
pp. 2146
Author(s):  
Bonthu Mamatha Bharathi ◽  
Raveena Gullapalli
Keyword(s):  
Risk Factor ◽  
Carotid Artery ◽  
Ischaemic Stroke ◽  
Carotid Stenosis ◽  
Carotid Artery Stenosis ◽  
Acute Onset ◽  
Artery Stenosis ◽  
Doppler Study ◽  
Diastolic Velocity ◽  
Asymptomatic Patients

Background: Extra cranial carotid disease due to arteriosclerosis is usually associated with hypercholesterolemia and hyperlipidemia. Extra cranial carotid stenosis has been found to be less prevalent in black American and in Egyptians while intracranial disease is far more common Various methods includes transcranial doppler (TCD) ultrasonography, cerebral angiography, computed tomography angiography (CTA) and magnetic resonance angiography (MRA).Methods: All patients with ischaemic stroke of acute onset admitted in the medical wards of Konaseema institute of medical sciences between June 2018 and January 2019 were included in the study. All patients were subjected to CT scan brain study and colour Doppler study of extra cranial carotid arteries and vertebral arteries. Systolic and diastolic velocity of blood flow, carotid intimal medial thickness, presence of athermanous plaque and thrombus was looked for and then the percentage of stenosis of the affected arteries was calculated.Results: In the present study 0ut of 23 patients with carotid stenosis 9 patients had mild carotid stenosis, 8 patients had moderate stenosis and 6 patients had severe stenosis. Out of 23 patients with carotid stenosis the 11 patients have stenosis in the right carotid and 12 patients had stenosis in the left side. The site of stenosis is ICA in 17 patients and CCA in 6 patients.Conclusions: In present study every patient with carotid artery stenosis had one or the other risk factor for carotid atherosclerosis. In other words, there was no patient with carotid artery stenosis, without any risk factor in present study. Hence asymptomatic patients with these risk factors should be screened for carotid stenosis to prevent stroke.

Abstract 2352: 18F-fluorodeoxyglucose PET Can Identify The Inflamed and Vulnerable Carotid Plaque - A Prospective Study in Japan

Stroke ◽  
2012 ◽  
Vol 43 (suppl_1) ◽  
Author(s):  
Satoshi Kuroda ◽  
Hisayasu Saito ◽  
Katsuhiko Maruichi ◽  
Naoki Nakayama ◽  
Kenji Hirata ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Prospective Study ◽  
Carotid Artery Stenosis ◽  
Fdg Pet ◽  
Vulnerable Plaque ◽  
Japanese Patients ◽  
Artery Stenosis ◽  
Fdg Uptake ◽  
Standardized Uptake Values ◽  
18F Fdg

Objective - There are few studies that denote the validity of 8F-fluorodeoxyglucose (FDG) PET to detect the inflammation of severe (>70%) carotid artery stenosis in Asian populations. This study was aimed to clarify whether 18F-FDG PET can identify inflamed and vulnerable plaque at higher risk for subsequent ischemic stroke in Japanese patients with severe carotid artery stenosis. Methods - This prospective study included 33 patients with severe carotid artery stenosis between 2006 and 2011. Of these, 12 patients were symptomatic and other 21 were asymptomatic. There were 28 males and 5 females. Their mean age was 71.1 ± 8.2 years, ranging from 48 to 85. Their clinical data were precisely collected. All 33 patients underwent 18F-FDG PET and ultrasound sonography (US) to evaluate the plaque composition prior to carotid endarterectomy (CEA). FDG uptake was quantified by maximum standardized uptake values (SUV). Following surgery, the specimens were stained with the antibodies against CD68 and MMP-9. Results - High FDG uptake (SUV>2.0) was observed in 15 (45%) of 33 operated plaques. High FDG uptake significantly correlated with the other vascular disorders (P=0.048), echolucent plaque (P=0.041), lipid-rich plaque (P<0.001), CD68 expression (P<0.001), and MMP-9 expression (P=0.002). 18F-FDG PET showed significantly higher sensitivity and specificity to identify lipid-rich and CD68-positive plaque than US. However, high FDG uptake was not related to patients’ gender, age, and the degree of stenosis. There was no significant correlation between FDG uptake and symptomatic or asymptomatic patients. Conclusion - These findings strongly suggest that 18F-FDG PET would provide more valuable information to identify the inflamed, vulnerable plaque than conventional ultrasound in Japanese patients with severe carotid artery stenosis.

scholarly journals Prevalence and risk factors of symptomatic carotid stenosis in patients with recent transient ischaemic attack or ischaemic stroke in the Netherlands

2020 ◽  
Vol 5 (3) ◽  
pp. 271-277
Author(s):  
Melina GHE den Brok ◽  
Laurien S Kuhrij ◽  
Bob Roozenbeek ◽  
Aad van der Lugt ◽  
Pieter HE Hilkens ◽  
...  
Keyword(s):  
Risk Factors ◽  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Ischaemic Stroke ◽  
Transient Ischaemic Attack ◽  
Carotid Artery Stenosis ◽  
Internal Carotid ◽  
Internal Carotid Artery Stenosis ◽  
Artery Stenosis ◽  
Ischaemic Attack

Introduction Literature on prevalence of symptomatic internal carotid artery stenosis is scarce and heterogeneous. Prevalence may have decreased in recent years due to improved management of cardiovascular risk factors. We aim to estimate current prevalence and identify risk factors of ipsilateral internal carotid artery stenosis in patients with recent hemispheric transient ischaemic attack or ischaemic stroke in the Netherlands. Patients and methods We included consecutive adult patients admitted to two large hospitals in the Netherlands in 2014 who suffered from amaurosis fugax, retinal ischaemia, transient ischaemic attack or ischaemic stroke in the vessel territory of the internal carotid artery. Primary outcome was presence of ipsilateral internal carotid artery stenosis (degree subdivided following NASCET criteria), as assessed with duplex ultrasonography, computed tomography angiography and/or magnetic resonance angiography. We used univariable and multivariable logistic regression to identify risk factors for the presence of a 50–100% internal carotid artery stenosis. Results We analysed 883 consecutive patients with recent transient ischaemic attack or ischaemic stroke. Of these, 110 (12.5%) had 50–99% ipsilateral internal carotid artery stenosis. Subgroup analyses showed higher prevalence of any degree of internal carotid artery stenosis for male sex and White patients. In adjusted analyses, higher age (odds ratio 1.4/10 years; 95% confidence interval 1.16–1.63), male sex (odds ratio 2.8; 95% confidence interval 1.83–4.19), retinal ischaemia (odds ratio 2.5; 95% confidence interval 1.32–4.76) and current smoking (odds ratio 1.8; 95% confidence interval 1.09–2.79) were statistically significant risk factors for 50–100% internal carotid artery stenosis. Conclusion The prevalence of internal carotid artery stenosis seems to be lower in patients with recent transient ischaemic attack or ischaemic stroke than stated in previous studies. We found that higher age, male sex, White ethnicity, retinal ischaemia and current smoking were important risk factors for symptomatic internal carotid artery stenosis.

Risk, causes, and prevention of ischaemic stroke in elderly patients with symptomatic internal-carotid-artery stenosis

The Lancet ◽  
2001 ◽  
Vol 357 (9263) ◽  
pp. 1154-1160 ◽  
Author(s):  
Sonia Alamowitch ◽  
Michael Eliasziw ◽  
Ale Algra ◽  
Heather Meldrum ◽  
Henry JM Barnett
Keyword(s):  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Elderly Patients ◽  
Ischaemic Stroke ◽  
Carotid Artery Stenosis ◽  
Internal Carotid ◽  
Internal Carotid Artery Stenosis ◽  
Artery Stenosis

scholarly journals A STUDY ON PREVALENCE OF CAROTID ARTERY STENOSIS IN ACUTE ISCHAEMIC STROKE PATIENTS

2016 ◽  
Vol 5 (103) ◽  
pp. 7559-7565
Author(s):  
Kamatchi Karunanidhi ◽  
Dhurgesa Nanthini Vijaya Sundaram ◽  
Murugarajan Singaram
Keyword(s):  
Carotid Artery ◽  
Ischaemic Stroke ◽  
Acute Ischaemic Stroke ◽  
Carotid Artery Stenosis ◽  
Artery Stenosis ◽  
Stroke Patients

Asymptomatic Carotid Artery Stenosis Screening in Patients with Lower Extremity Atherosclerosis: A Prospective Study

1997 ◽  
Vol 11 (4) ◽  
pp. 374-377 ◽  
Author(s):  
Christian de Virgilio ◽  
Katayoun Toosie ◽  
Tracey Arnell ◽  
Roger J. Lewis ◽  
Carlos E. Donayre ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Lower Extremity ◽  
Prospective Study ◽  
Carotid Artery Stenosis ◽  
Artery Stenosis ◽  
Asymptomatic Carotid ◽  
Asymptomatic Carotid Artery Stenosis ◽  
A Prospective Study
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