scholarly journals The importance of autologous blood transfusion in lung transplantation and cardiovascular surgeries

2021 ◽  
Vol 29 (3) ◽  
pp. 354-359
Author(s):  
Tevfik İlker Akçam ◽  
Ali Özdil ◽  
Önder Kavurmacı ◽  
Pelin Öztürk ◽  
Deniz Can Başaran ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Lung Transplantation ◽  
Blood Product ◽  
Autologous Blood ◽  
Autologous Blood Transfusion ◽  
Complication Rates ◽  
Allogenic Transfusion ◽  
Significant Difference ◽  
Group 2 ◽  
Group 1

Background: In this study, we aimed to investigate the effect of using autologous blood recovery systems on transfusion-related complications in patients undergoing lung transplantation and cardiovascular surgeries. Methods: Between May 2016 and May 2019, a total of 104 patients (90 males, 14 females; mean age: 59.3±16.4 years; range, 12 to 89 years) in whom cell-saver and autologous blood recovery systems were used during lung transplantation or cardiovascular surgeries were retrospectively analyzed. The patients were divided into two groups as Group 1 (n=61) consisting of patients who received autologous blood transfusion and as Group 2 (n=43) consisting of patients who did not. Data including demographic and clinical characteristics of the patients, operation data, and postoperative complications were recorded. Results: The total amount of transfused blood/blood product was found to be significantly higher in Group 1 (p=0.018). However, transfusionrelated complications were found to be higher in Group 2 (p=0.0261). There was no significant difference in the length of hospital stay between the groups. Conclusion: Autologous blood transfusion may prevent the development of transfusion-related complications by reducing the amount of allogenic transfusion in major surgical procedures. In our study, the autologous blood transfusion was used in critical patients with major bleeding and, therefore, the total amount of transfused blood/blood product was higher in these patients. Nevertheless, lower complication rates in this patient group emphasize the importance of autologous blood transfusion.

scholarly journals Comparison of the results of percutaneous nephrolithotomy in different age groups

2018 ◽  
Vol 5 (12) ◽  
pp. 3888
Author(s):  
Ali Borekoglu ◽  
Ibrahim Atilla Aridogan ◽  
Mutlu Deger ◽  
Onur Karsli ◽  
Volkan Izol
Keyword(s):  
Blood Transfusion ◽  
Percutaneous Nephrolithotomy ◽  
Preoperative Evaluation ◽  
Control Group ◽  
Perioperative Bleeding ◽  
Significant Difference ◽  
The Mean ◽  
Group 2 ◽  
And Control ◽  
Group 1

Background: Evaluation of feasibility, safety and effectiveness of percutaneous nephrolithotomy (PCNL) in different age groups.Methods: Between July 1997-October 2012, 233 patients who were 65 years old and older were included in this study. These patients were divided into two age subgroups used in gerontology research. Group 1 was defined as patients 65-74 years old, Group 2 was older than 74 years old. Data from patient records, including demographic characteristics, preoperative evaluation, operative details, and complications were retrospectively analyzed and compared with control group data.Results: The mean age of 233 patients was 69.7±4.6 years. The mean operative times for Group 1, group 2 and the control group were 76.2±47.3mins, 92.9±47.6mins, 77±44mins, respectively and there was no statistically significant difference between groups 1 and 2 and the control group (p>0.05). Twenty-eight of the 233 patients (12%) needed blood transfusion due to perioperative bleeding. The transfusion rates of groups 1 and 2 were 11.3% and 16.7%, respectively. There was no statistically significant difference between the study groups and control group for blood transfusion rates (p>0.05). There was no statistically significant difference in complications between the study and control groups (p>0.05).Conclusions: In geriatric patients, stone-free rates, transfusion rates and other operation parameters are similar to younger populations when experienced surgeons perform PCNL. Despite comorbidities and decreased body reserve, PCNL can be performed without a significant increase in complications in different ages.

Presurgical treatment with somatostatin analogs in patients with acromegaly: effects on the remission and complication rates

2006 ◽  
Vol 104 (6) ◽  
pp. 899-906 ◽  
Author(s):  
Marco Losa ◽  
Pietro Mortini ◽  
Laura Urbaz ◽  
Paolo Ribotto ◽  
Tristana Castrignanò ◽  
...  
Keyword(s):  
Tumor Size ◽  
Surgical Outcome ◽  
Somatostatin Analogs ◽  
Preoperative Treatment ◽  
Complication Rates ◽  
Surgery Group ◽  
Significant Difference ◽  
Group 2 ◽  
Matching Criteria ◽  
Group 1

Object The question of whether preoperative therapy with somatostatin analogs can improve surgical outcome in acromegaly has not been definitively answered. In this paper, the authors report the effects of preoperative treatment with somatostatin analogs in a large sample of patients with acromegaly. Methods Between 1990 and 2003, 399 consecutive patients with acromegaly underwent surgery at the Istituto Scientifico San Raffaele. Thirty-three patients who had previously undergone surgery or radiation treatment, 48 patients treated with somatostatin analogs for fewer than 3 months, and patients who had stopped therapy for too long a time before surgery were excluded from the study. One hundred forty-three patients who had received somatostatin analogs prior to surgery (Group 1) were randomly matched to 143 patients who had never been treated with somatostatin analogs (Group 2). Matching criteria were tumor size and invasiveness into the cavernous sinus. Before surgery, Group 1 patients showed reduction of growth hormone levels to less than 50% of baseline in 64% of cases, but insulin-like growth factor–I was normalized in only 19.5%. Surgical remission occurred in 81 Group 1 patients (56.6%) and in 91 Group 2 patients (63.6%; p = 0.28). No significant difference in the remission rate was observed when cases were analyzed according to tumor size or invasiveness. Logistic regression analysis confirmed that pretreatment with somatostatin analogs was not associated with surgical outcome. Surgical morbidity was mild and similar in Group 1 and Group 2 patients (7 and 5.6%, respectively; p = 0.81). Surgical remission and complication rates in patients with acromegaly who received treatment with somatostatin analogs prior to surgery were not significantly different from those of matched patients who did not receive these agents. Conclusions At present, the routine use of presurgical therapy with somatostatin analogs for patients with acromegaly cannot be recommended.

Usefulness of autologous blood transfusion for avoiding allogenic transfusion and infectious complications after esophageal cancer resection

Surgery ◽  
2000 ◽  
Vol 127 (2) ◽  
pp. 185-192 ◽  
Author(s):  
Yoshihiro Kinoshita ◽  
Harushi Udagawa ◽  
Kenji Tsutsumi ◽  
Masanori Ueno ◽  
Toyohide Nakamura ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Blood Transfusion ◽  
Autologous Blood ◽  
Infectious Complications ◽  
Autologous Blood Transfusion ◽  
Cancer Resection ◽  
Allogenic Transfusion

Postoperative Inflammatory Response after Autologous and Allogeneic Blood Transfusion

1997 ◽  
Vol 87 (3) ◽  
pp. 511-516 ◽  
Author(s):  
Anders Avall ◽  
Monica Hyllner ◽  
Jan Peter Bengtson ◽  
Lars Carlsson ◽  
Anders Bengtsson
Keyword(s):  
Blood Transfusion ◽  
Autologous Blood ◽  
Plasma Concentrations ◽  
Allogeneic Blood Transfusion ◽  
Allogeneic Blood ◽  
Autologous Blood Transfusion ◽  
Blood Transfusions ◽  
Joint Replacement Surgery ◽  
Autologous Whole Blood ◽  
Significant Difference

Background Allogeneic blood transfusions cause immunosuppression. The aim of this study was to determine whether complement anaphylatoxins, cytokines, or both are released in the recipient, after blood transfusions in general, and after autologous blood transfusions in particular. Methods Thirty-one patients having total hip joint replacement surgery were randomized to receive either allogeneic red blood cells (n = 15) or predeposited autologous whole blood transfusion (n = 16). Plasma concentrations of the anaphylatoxins C3a and C5a, the terminal C5b-9 complement complex, and cytokines IL-6 and IL-8 in the recipients were repeatedly analyzed before, during, and after surgery. Results Significantly increased concentrations of IL-6 and IL-8 appeared in both groups, with a significantly greater increase in the autologous blood group. Patients in both groups developed a moderate but significant increase of C3a without a significant difference between them. C5a and terminal C5b-9 complement complex were not greatly changed. Conclusions The study showed a greater increase in cytokine concentration after autologous blood transfusion than after allogeneic blood transfusion. The lower response in the latter may result from transfusion-induced suppression of cellular immunity.

Autotransfusion in urology: Control study on 59 cases

1992 ◽  
Vol 59 (1_suppl) ◽  
pp. 73-75
Author(s):  
S. Spatafora ◽  
D. Lasagni ◽  
R. Baricchi ◽  
R. Rossi-Cesolari ◽  
C. Lusenti ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Autologous Blood ◽  
Performance Status ◽  
Hemoglobin Concentration ◽  
Control Group ◽  
Autologous Blood Transfusion ◽  
Homologous Blood ◽  
Significant Difference ◽  
Discharge From Hospital ◽  
Control Study

We studied the hematologic and clinical patterns of 59 patients undergoing urologic surgery who entered in a predeposit autologous blood transfusion program and of 59 controls to evaluate the feasibility and safety of the autotransfusional procedure in Urology. 174 units of autologous blood were donated (average 2.94 per pt.) with a high frequency of donation (2.6 days). No side effect or alteration of performance status was reported. We had a dramatic reduction of the need for homologous blood (2.21 units per pt.) without a significant difference of the average hemoglobin concentration between the two groups at discharge from hospital. Autotransfusion has significant advantages compared with conventional transfusion, reducing the complications correlated with homologous blood infusion as also our study demonstrated. Infact 1 post-transfusional hepatitis and 3 complications due to an alteration of coagulation were reported in the control group. The procedure resulted safe and feasible in most urologic operations that require almost two units of blood transfusion.

scholarly journals Evaluation of Clinical Parameters in FMT-Application of a Vibrant Soundbridge® at the Short Incus Process Compared to Conventional FMT-Application

2020 ◽  
pp. 1-4
Author(s):  
Markus Pirlich ◽  
Andreas Dietz ◽  
Markus Pirlich ◽  
Viktor Kunz
Keyword(s):  
Pure Tone ◽  
Revision Rate ◽  
University Hospital ◽  
Complication Rates ◽  
Vibrant Soundbridge ◽  
Surgical Time ◽  
Pure Tone Audiogram ◽  
Significant Difference ◽  
Group 2 ◽  
Group 1

Background: The application of the Floating Mass Transducer (FMT) of a Vibrant Soundbridge (VSB) to the short incus process is intended to reduce both the surgery time and the complication and revision rate compared to other forms of application. In addition to collecting these parameters, the aim of this study is to investigate the primary audiological outcome of patients with an FMT application to the short process compared to the conventional methods. Methods: The present study retrospectively examined a total of n=36 patients who received a VSB between 01/2015 and 08/2018 at the ENT University Hospital Leipzig. In n=12 patients (group 1) the FMT was coupled to the short process, in n=24 patients (group 2) to other ear structures. The audiological results were evaluated pre- and postoperatively in the pure tone audiogram according to the recommendations of the AAO-HNS (1995) and the intelligibility (Freiburger, monosyllabic) was measured at 65 dB in the speech audiogram. In addition, the revision and complication rates as well as the surgical time were evaluated. Results: The audiological outcome of group 2 was significantly better postoperatively in both the pure tone (p<.001) and speech audiogram (p=.012). The surgery time of group 1 was significantly shorter (p=.002), but with a slightly increased revision rate (p=.519). The complication rate of group 2 was slightly higher, with no statistically significant difference to group 1 (p=.185). Conclusions: The FMT application on the short ambos process does not seem to offer any advantage in terms of audiological outcome, but at the same time is associated with a significantly shorter surgery time. There are no statistically significant differences in revision and complication rates.

scholarly journals Comparison of penile prosthesis types' complications: A retrospective analysis of single center

2020 ◽  
Vol 92 (4) ◽  
Author(s):  
Erdem Kisa ◽  
Mehmet Zeynel Keskin ◽  
Cem Yucel ◽  
Murat Ucar ◽  
Okan Yalbuzdag ◽  
...  
Keyword(s):  
Postoperative Complication ◽  
Penile Prosthesis ◽  
Diabetes Type 2 ◽  
Pelvic Surgery ◽  
Complication Rates ◽  
Initial Surgery ◽  
Significant Difference ◽  
Lower Complication ◽  
Group 2 ◽  
Group 1

Objectives: The aim of this study was to compare clinical outcomes and complication rates associated with semirigid (malleable) and inflatable penile prostheses (PPs) and investigate the factors that influence these complications. Material and methods: The records of 131 patients who had undergone penile prosthesis implantation (PPI) in our clinic due to erectile dysfunction (ED) between January 2010 and March 2019 were retrospectively reviewed. The initial surgery included 116 primary implants and 15 men had two revision operations. Patients were assigned to two groups as semirigid (malleable) PPI (group 1) and inflatable PPI (group 2) patients, and obtained data were compared across these two groups. Results: Group 1 included 93 patients, while Group 2 included 38 patients. Postoperative complication rates of Group 1 were 8.6% (n = 8), and Group 2 were 21% (n = 8), and the comparison of postoperative complication rates revealed a statistically significant difference between the two groups (p = 0.025). The majority of these complications (50%) was constituted by mechanical failure associated with inflatable PPs. When patients were further segregated as those with and without diabetes type 2 (DM) and those who had and had not undergone radical pelvic surgery (RPS), the comparison of complication rates across these subgroups did not yield any significant difference. Conclusions: We determined in this study that semirigid (malleable) PPs were associated with lower complication rates compared to the inflatable group, particularly with regard to mechanic failure, and that DM and history of RPS did not make a difference in complication rates in patients planned to undergo PPI.

scholarly journals Comparing Blind and Ultrasound-Guided Retrobulbar Nerve Blocks in Equine Cadavers: The Training Effect

Animals ◽  
2022 ◽  
Vol 12 (2) ◽  
pp. 154
Author(s):  
Hanneke Hermans ◽  
Ralph A. Lloyd-Edwards ◽  
Aukje J. H. Ferrão-van Sommeren ◽  
Anne A. Tersmette ◽  
Jacobine C. M. Schouten ◽  
...  
Keyword(s):  
Central Position ◽  
Blue Dye ◽  
Complication Rates ◽  
Nerve Blocks ◽  
Us Guidance ◽  
Needle Position ◽  
Significant Difference ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

In standing ophthalmic surgery in horses, a retrobulbar nerve block (RNB) is often placed blindly for anesthesia and akinesia. The ultrasound (US)-guided RNB may have fewer complications, but the two techniques have only been compared once in equine cadavers. This study compares the techniques for success and complication rates and analyzes the effect of training on US guidance. Twenty-two equine cadavers were divided into three groups: blind RNBs were performed bilaterally in eight cadavers, US-guided RNBs were performed bilaterally in seven cadavers, and after US-guided training, blind RNBs were performed bilaterally in seven cadavers. All RNBs were performed by the same two inexperienced operators, and a combination of contrast medium (CM; 1.25 mL) and methylene blue dye (1.25 mL) were injected (2.5 mL total volume). Needle positioning in the periorbita and the distance of the CM to the optic foramen were assessed using computerized tomography (CT). Dye spreading was evaluated by dissection. In group 1, 37.5% of the injections were in the optimal central position in the periorbita; in group 2, 75% and in group 3, 71.4%. There was no significant difference between the groups regarding needle position (groups 1 and 2 p = 0.056; groups 1 and 3 p = 0.069, groups 2 and 3 p = 0.8). The mean CM distribution distance was not significantly different between all groups. Group 1 had 18.75% intraocular injections versus 0% in group 2 and 7.1% in group 3 (not significant). US guidance showed no significant increases in accuracy nor decreases in complications. However, the effects on accuracy showed a trend towards significant improvement, and larger scale follow-up studies might show significant training effects on US guidance.

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