Dynamic Imaging with X-ray Holography

Phase-contrast X-ray imaging using a paper analyzer enables the visualization of X-ray transparent biological structures using the refractive properties of the sample. The technique measures the sample-induced distortions of a spatially random reference pattern to retrieve quantitative sample information. This phase-contrast method is promising for biomedical application due to both a simple experimental set-up and a capability for real-time imaging. The authors explore the experimental configuration required to achieve robustness and accuracy in terms of (i) the paper analyzer feature size, (ii) the sample-to-detector distance, and (iii) the exposure time. Results using a synchrotron source confirm that the technique achieves accurate phase retrieval with a range of paper analyzers and at exposures as short as 0.5 ms. These exposure times are sufficiently short relative to characteristic physiological timescales to enable real-time dynamic imaging of living samples. A theoretical guide to the choice of sample-to-detector distance is also derived. While the measurements are specific to the set-up, these guidelines, the example speckle images, the strategies for analysis in the presence of noise and the experimental considerations and discussion will be of value to those who wish to use the speckle-tracking paper analyzer technique.

Download Full-text

Dynamic imaging of the lungs using x-ray phase contrast

Physics in Medicine and Biology ◽

10.1088/0031-9155/50/21/006 ◽

2005 ◽

Vol 50 (21) ◽

pp. 5031-5040 ◽

Cited By ~ 86

Author(s):

R A Lewis ◽

N Yagi ◽

M J Kitchen ◽

M J Morgan ◽

D Paganin ◽

...

Keyword(s):

Phase Contrast ◽

Dynamic Imaging ◽

X Ray

Download Full-text

Evaluation of microbubble contrast agents for dynamic imaging with x-ray phase contrast

Scientific Reports ◽

10.1038/srep12509 ◽

2015 ◽

Vol 5 (1) ◽

Cited By ~ 17

Author(s):

T. P. Millard ◽

M. Endrizzi ◽

N. Everdell ◽

L. Rigon ◽

F. Arfelli ◽

...

Keyword(s):

Contrast Agents ◽

Phase Contrast ◽

Dynamic Imaging ◽

X Ray ◽

Microbubble Contrast Agents

Download Full-text

Dynamic crystal rotation resolved by high-speed synchrotron X-ray Laue diffraction

Journal of Synchrotron Radiation ◽

10.1107/s160057751600223x ◽

2016 ◽

Vol 23 (3) ◽

pp. 712-717 ◽

Cited By ~ 3

Author(s):

J. W. Huang ◽

J. C. E ◽

J. Y. Huang ◽

T. Sun ◽

K. Fezzaa ◽

...

Keyword(s):

High Speed ◽

Split Hopkinson Pressure Bar ◽

Dynamic Compression ◽

Dynamic Imaging ◽

Hopkinson Pressure Bar ◽

Contrast Imaging ◽

Laue Diffraction ◽

X Ray ◽

Rotation Axes ◽

Crystal Rotation

Dynamic compression experiments are performed on single-crystal Si under split Hopkinson pressure bar loading, together with simultaneous high-speed (250–350 ns resolution) synchrotron X-ray Laue diffraction and phase-contrast imaging. A methodology is presented which determines crystal rotation parameters,i.e.instantaneous rotation axes and angles, from two unindexed Laue diffraction spots. Two-dimensional translation is obtained from dynamic imaging by a single camera. High-speed motion of crystals, including translation and rotation, can be tracked in real timeviasimultaneous imaging and diffraction.

Download Full-text

Highly Efficient Copper Halide Scintillators for High-Performance and Dynamic X-ray Imaging

Nanoscale ◽

10.1039/d1nr03996b ◽

2021 ◽

Author(s):

Quan Zhou ◽

Jiwei Ren ◽

Jiawen Xiao ◽

Lin Lei ◽

Feiyi Liao ◽

...

Keyword(s):

Homeland Security ◽

High Performance ◽

Low Cost ◽

Light Yield ◽

Medical Diagnostics ◽

Dynamic Imaging ◽

Copper Halide ◽

X Ray ◽

X Ray Imaging ◽

High Light Yield

Progress towards high performance X-ray detection and dynamic imaging applications, including nondestructive inspection, homeland security, and medical diagnostics, requires scintillators with high light yield, reasonable decay time, low cost, and...

Download Full-text

Quantum Interference in Ionization of Excited Molecules: X-Ray Emission Control and Dynamic Imaging

Springer Series in Chemical Physics - Progress in Ultrafast Intense Laser Science VI ◽

10.1007/978-3-642-15054-8_4 ◽

2010 ◽

pp. 75-88

Author(s):

Mikhail Yu. Emelin ◽

Mikhail Yu. Ryabikin ◽

Alexander M. Sergeev

Keyword(s):

Quantum Interference ◽

Emission Control ◽

Dynamic Imaging ◽

X Ray ◽

Excited Molecules

Download Full-text

A double-radius Gandolfi X-ray camera for the generation of powder-like diffractograms of small single crystals, using an imaging plate detector

Journal of Applied Crystallography ◽

10.1107/s0021889801016594 ◽

2002 ◽

Vol 35 (1) ◽

pp. 13-16 ◽

Cited By ~ 4

Author(s):

H. H. Otto ◽

W. Hofmann ◽

K. Schröder

Keyword(s):

Single Crystals ◽

Dynamic Imaging ◽

Short Exposure ◽

Imaging Plate ◽

Data Sets ◽

Short Exposure Time ◽

X Ray ◽

Diffraction Patterns ◽

Non Destructive ◽

Plate System

This is a report on the construction and the main features of an X-ray camera following the Debye–Scherrer geometry, combined with a sample mounting and rotation device for single crystals as first suggested by Gandolfi. Doubling of the camera radius and replacing of the wet-film technology by a highly dynamic imaging plate system allows well resolved digital diffraction patterns to be recorded within a short exposure time. Sophisticated calibration, correction and evaluation possibilities are supported by suitable software. Further optional improvements, such as the evacuation of the camera, the adaptation of totally reflecting collimators for an almost parallel primary X-ray beam and a built-in instead of an external imaging plate readout device, will further improve the resolution and peak to background ratio. The simple and versatile apparatus is indispensable for the fast and non-destructive identification of unique mineralogical or technical micro-samples in the form of single-crystal pieces. Initial representative data sets attest to the accuracy, efficiency and sensitivity of the method presented.

Download Full-text