scholarly journals Environmental Factors and Male Infertility

2018 ◽  
Author(s):  
Qiuqin Tang ◽  
Wei Wu ◽  
Jing Zhang ◽  
Rong Fan ◽  
Mu Liu
Keyword(s):  
Environmental Factors ◽  
Male Infertility

Role of Environmental Factors and Gonadotoxin Exposure in Unexplained Male Infertility

2015 ◽  
pp. 121-138 ◽  
Author(s):  
Pieter Johann Maartens ◽  
Yapo Guillaume Aboua ◽  
Stefan S. Plessis
Keyword(s):  
Environmental Factors ◽  
Male Infertility

scholarly journals Influence of Lifestyle and Environmental Factors on Semen Quality in Ghanaian Men

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Richard Michael Blay ◽  
Abigail Duah Pinamang ◽  
Augustine E. Sagoe ◽  
Ewurama Dedea Ampadu Owusu ◽  
Nii Koney-Kwaku Koney ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Male Infertility ◽  
Sperm Motility ◽  
Semen Quality ◽  
Sperm Quality ◽  
Sperm Count ◽  
Semen Analysis ◽  
Reproductive Age ◽  
Adult Males ◽  
Lifestyle Habits

Introduction. Male infertility is known to contribute about half of all infertility cases. In Ghana, the prevalence of male infertility is higher (15.8%) than in females (11.8%). Sperm quality is associated with the likelihood of pregnancy and known to be the cause of male fertility problems 90% of the time. Exposure to certain environmental factors reduces semen quality in men. The study examined the effects of environmental and lifestyle factors on semen quality in Ghanaian men. Materials and Methods. This was a cross-sectional study involving 80 apparent healthy adult males in their reproductive age. Participants were males referred to the laboratory (Immunology Unit of the Korle-Bu Teaching Hospital) for semen analysis test and/or culture and sensitivity. Participants were made to fill out a questionnaire which entailed selected environmental factors (accidents or trauma, exposure to chemicals, radiation, and heat) and lifestyle habits (including alcohol consumption, smoking, and whether participants sat more or less than 4 hours per day). Semen samples were then collected by masturbation into sterile containers and analysed in accordance with WHO guidance for semen analysis within 60 minutes after ejaculation and collection. Results. About 69% of participants had semen pH within the normal range compared to 15% whose pH were lower than 7.2. There was a significantly high number of immotile sperm cells ( p value = 0.017) in participants who sat for more than 4 hours as compared to those that sat for less than 4 hours in a day. Active sperm motility and viability showed significant increase ( p value = 0.002 and 0.009, respectively) in participants who kept their cell phones in their side pockets. Smoking produced a twofold decrease in sperm count as smokers had a significantly lower sperm count ( 12.28 ± 10.95 × 10 6 /ml) compared to the smoke-free ( 23.85 ± 22.14 × 10 6 /ml). For exposure to STDs, no significant differences were recorded among study groups concerning semen quality. Conclusion. Sperm quality in Ghanaian men is associated with lifestyle habits. Smoking and sitting for long hours influenced sperm motility and count, respectively. Knowledge of the factors that influence sperm quality in this geographical region can contribute to informed decisions on effective management of infertility in Ghanaian men.

scholarly journals A Review on Male Infertility - Environmental Factors, Pathophysiological and Oxidative Stress

2021 ◽  
Vol 10 (44) ◽  
pp. 3798-3804
Author(s):  
Lata Kanyal Butola ◽  
Archana Dhok ◽  
Deepika Kanyal ◽  
Anjali Vagga
Keyword(s):  
Oxidative Stress ◽  
Environmental Factors ◽  
Male Infertility ◽  
Illicit Drugs ◽  
Semen Quality ◽  
Coffee Consumption ◽  
Paternal Age ◽  
Industrial Chemicals ◽  
Nutrition Intake ◽  
Poor Nutrition

Male infertility is one of the rising global problems with an increasing decline in male semen quality among men living in Asia, Europe, Africa and North America. Infertility is defined as the failure of conception after at least 12 months of unprotected intercourse. Globally 70 million people are affected by infertility. Environmental, occupational and modifiable lifestyle factors may contribute to this decline of male fertility. Various factors associated with male infertility include smoking cigarettes, alcohol intake, use of illicit drugs, obesity, genetic factors, heavy metals, psychological stress, exposure to pesticides and industrial chemicals, poor nutrition intake, oxidative stress, sedentary lifestyle, advanced paternal age, diet and coffee consumption. KEY WORDS Infertility, Antioxidant, Environmental Factors, Endocrine Factors

Epidemiology of Male Infertility

2018 ◽  
Author(s):  
Omer A Raheem ◽  
Thomas J Walsh
Keyword(s):  
Environmental Factors ◽  
Male Infertility ◽  
Risk Groups ◽  
Epidemiologic Studies ◽  
World Health ◽  
Patient Counseling ◽  
Unprotected Sexual Intercourse ◽  
Geographical Variations ◽  
Health Organization ◽  
The Relationship

Infertility is a complex and incompletely understood disease that impacts 10 to 15% of reproductive-aged couples seeking to conceive. The World Health Organization defines infertility as the failure to conceive a clinical pregnancy after 12 or more of regular unprotected sexual intercourse. It likely involves the interaction among many variables, including age, race, ethnicity, and geography, that are laid upon the foundation of genetics and chronic medical conditions and further modified by environmental factors. A plethora of contemporary epidemiologic studies have been published detailing the relationship between male infertility, medical diseases, and environmental exposures with the primary goal of better characterizing their association, identifying risk factors, and providing more effective patient counseling and subsequent treatments. In this chapter, we aim to critically analyze available data and integrate the understanding of epidemiology and male infertility in an effort to provide clear guidance to a larger audience of clinicians of various subspecialties that encounter men with reproductive challenges. This review contains 1 figure, 8 tables, and 62 references. Key Words: at-risk groups, conditions, definitions, environmental factors,epidemiology, male fertility, racial geographical, variations

Epidemiology of Male Infertility

2018 ◽  
Author(s):  
Omer A Raheem ◽  
Thomas J Walsh
Keyword(s):  
Environmental Factors ◽  
Male Infertility ◽  
Risk Groups ◽  
Epidemiologic Studies ◽  
World Health ◽  
Patient Counseling ◽  
Unprotected Sexual Intercourse ◽  
Geographical Variations ◽  
Health Organization ◽  
The Relationship

Infertility is a complex and incompletely understood disease that impacts 10 to 15% of reproductive-aged couples seeking to conceive. The World Health Organization defines infertility as the failure to conceive a clinical pregnancy after 12 or more of regular unprotected sexual intercourse. It likely involves the interaction among many variables, including age, race, ethnicity, and geography, that are laid upon the foundation of genetics and chronic medical conditions and further modified by environmental factors. A plethora of contemporary epidemiologic studies have been published detailing the relationship between male infertility, medical diseases, and environmental exposures with the primary goal of better characterizing their association, identifying risk factors, and providing more effective patient counseling and subsequent treatments. In this chapter, we aim to critically analyze available data and integrate the understanding of epidemiology and male infertility in an effort to provide clear guidance to a larger audience of clinicians of various subspecialties that encounter men with reproductive challenges. This review contains 1 figure, 8 tables, and 62 references. Key Words: at-risk groups, conditions, definitions, environmental factors,epidemiology, male fertility, racial geographical, variations

scholarly journals Male infertility and environmental factors

2019 ◽  
Vol 4 (2) ◽  
pp. e28
Author(s):  
Antti Perheentupa
Keyword(s):  
Environmental Factors ◽  
Male Infertility

scholarly journals Male Infertility and Its Causes in Human

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Toshinobu Miyamoto ◽  
Akira Tsujimura ◽  
Yasushi Miyagawa ◽  
Eitetsu Koh ◽  
Mikio Namiki ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Male Infertility ◽  
Effective Treatment ◽  
Genetic Predisposition ◽  
Social Problems ◽  
Male Partner ◽  
Mature Sperm ◽  
Nonobstructive Azoospermia

Infertility is one of the most serious social problems facing advanced nations. In general, approximate half of all cases of infertility are caused by factors related to the male partner. To date, various treatments have been developed for male infertility and are steadily producing results. However, there is no effective treatment for patients with nonobstructive azoospermia, in which there is an absence of mature sperm in the testes. Although evidence suggests that many patients with male infertility have a genetic predisposition to the condition, the cause has not been elucidated in the vast majority of cases. This paper discusses the environmental factors considered likely to be involved in male infertility and the genes that have been clearly shown to be involved in male infertility in humans, including our recent findings.

scholarly journals Microarray technology offers a novel tool for the diagnosis and identification of therapeutic targets for male infertility

Reproduction ◽  
2006 ◽  
Vol 132 (1) ◽  
pp. 11-19 ◽  
Author(s):  
Zuping He ◽  
Wai-Yee Chan ◽  
Martin Dym
Keyword(s):  
Environmental Factors ◽  
Male Infertility ◽  
Expression Patterns ◽  
Environmental Pollutants ◽  
Gene Mutations ◽  
Genetic Alterations ◽  
Microarray Technology ◽  
Therapy Targets ◽  
Differential Gene

Male infertility is now a major reproductive health problem because of an increasing number of environmental pollutants and chemicals, which eventually result in gene mutations. Genetic alterations caused by environmental factors account for a significant percentage of male infertility. Microarray technology is a powerful tool capable of measuring simultaneously the expression of thousands of genes expressed in a single sample. Eventually, advances in genetic technology will allow for the diagnosis of patients with male infertility due to congenital reasons or environmental factors. Since its introduction in 1994, microarray technology has made significant advances in the identification and characterization of novel or known genes possibly correlated with male infertility in mice, as well as in humans. This provides a rational basis for the application of microarray to establishing molecular signatures for the diagnosis and gene therapy targets of male infertility. In this review, the differential gene expression patterns characterized by microarray in germ and somatic cells at different steps of development or in response to stimuli, as well as a number of novel or known genes identified to be associated with male infertility in mice and humans, are addressed. Moreover, issues pertaining to measurement reproducibility are highlighted for the application of microarray data to male infertility.

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