scholarly journals Bovine Feed Manipulation, Enhancement of Conjugated Linoleic Acid and Its Bioavailability

Author(s):  
Nazir Ahmad ◽  
Muhammad Kamran Khan ◽  
Muhammad Imran ◽  
Muhammad Nadeem Suleman ◽  
Sufyan Afzal
2010 ◽  
Vol 80 (1) ◽  
pp. 65-73 ◽  
Author(s):  
Pei-Min Chao ◽  
Wan-Hsuan Chen ◽  
Chun-Huei Liao ◽  
Huey-Mei Shaw

Conjugated linoleic acid (CLA) is a collective term for the positional and geometric isomers of a conjugated diene of linoleic acid (C18:2, n-6). The aims of the present study were to evaluate whether levels of hepatic α-tocopherol, α-tocopherol transfer protein (α-TTP), and antioxidant enzymes in mice were affected by a CLA-supplemented diet. C57BL/6 J mice were divided into the CLA and control groups, which were fed, respectively, a 5 % fat diet with or without 1 g/100 g of CLA (1:1 mixture of cis-9, trans-11 and trans-10, cis-12) for four weeks. α-Tocopherol levels in plasma and liver were significantly higher in the CLA group than in the control group. Liver α-TTP levels were also significantly increased in the CLA group, the α-TTP/β-actin ratio being 2.5-fold higher than that in control mice (p<0.01). Thiobarbituric acid-reactive substances were significantly decreased in the CLA group (p<0.01). There were no significant differences between the two groups in levels of three antioxidant enzymes (superoxide dismutase, glutathione peroxidase, and catalase). The accumulation of liver α-tocopherol seen with the CLA diet can be attributed to the antioxidant potential of CLA and the ability of α-TTP induction. The lack of changes in antioxidant enzyme protein levels and the reduced lipid peroxidation in the liver of CLA mice are due to α-tocopherol accumulation.


Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
C Wawrzenczyk ◽  
B Tubek ◽  
P Mitula ◽  
K Kempinska ◽  
J Wietrzyk

2008 ◽  
Vol 23 (1) ◽  
pp. 248-256 ◽  
Author(s):  
Zofia Żegarska ◽  
Beata Paszczyk ◽  
Zbigniew Borejszo

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