scholarly journals Potential Application of Nanoporous Materials in Biomedical Field

2021 ◽  
Author(s):  
Saraswati Prasad Mishra ◽  
Shweta Dutta ◽  
Anil Kumar Sahu ◽  
Koushlesh Mishra ◽  
Pankaj Kashyap

Nanoporous materials are the substances having pores of size 100 nanometers in a frame work organic or inorganic substance. These substances are used in medical devices such as bioartificial organ and biosensing. Nanoporous material has also importance in the field of diagnostics. This chapter basically explains about the nanoporous material in detail along with its types. The methods of fabrication of these nanoporous material area also explained. The chapter also deals with the characterization of the materials. Moreover present application of nanoporous material such as in the field of biomedicals along with the future prospects is explained in the present chapter.


1997 ◽  
Vol 28 (1) ◽  
pp. 51-64 ◽  
Author(s):  
S.K. Mishra ◽  
M.K. Jain ◽  
S.M. Seth

The flood waves are characterized within the frame-work of loop (or hysteresis) of rating curves. The National Weather Service's Dam Break Flood Forecasting Model is used to generate the flood waves in the downstream valley of the Bargi dam located in Central India. The quantified hystereses, η, of non-dimensional rating curves are related with the corresponding flood wave characteristics, viz., speed of travel, wave number, phase difference, and attenuation. The analysis has led to the development of an exact relationship between η and phase difference. Using the concept of wave zoning, the better performance of the hysteresis based criteria compared with the available criteria is verified using Convex and Muskingum-Cunge routing in the wave zones. η limits are specified for the applicability of these simplified routing models. Furthermore, the envisaged applications of the based analysis are introduced.



2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Lei Xiang ◽  
Wenguo Cui

Abstract During the past decades, photo-crosslinked gelatin hydrogel (methacrylated gelatin, GelMA) has gained a lot of attention due to its remarkable application in the biomedical field. It has been widely used in cell transplantation, cell culture and drug delivery, based on its crosslinking to form hydrogels with tunable mechanical properties and excellent bio-compatibility when exposed to light irradiation to mimic the micro-environment of native extracellular matrix (ECM). Because of its unique biofunctionality and mechanical tenability, it has also been widely applied in the repair and regeneration of bone, heart, cornea, epidermal tissue, cartilage, vascular, peripheral nerve, oral mucosa, and skeletal muscle et al. The purpose of this review is to summarize the recent application of GelMA in drug delivery and tissue engineering field. Moreover, this review article will briefly introduce both the development of GelMA and the characterization of GelMA. Finally, we discuss the challenges and future development prospects of GelMA as a tissue engineering material and drug or gene delivery carrier, hoping to contribute to accelerating the development of GelMA in the biomedical field. Graphical abstract



Author(s):  
Pushpesh Ranjan ◽  
Ayushi Singhal ◽  
Shalu Yadav ◽  
Neeraj Kumar ◽  
S. Murali ◽  
...  


2021 ◽  
Vol 291 ◽  
pp. 129562
Author(s):  
S.L. Amaya ◽  
G. Alonso-Núñez ◽  
J.N. Díaz De León ◽  
S. Fuentes ◽  
Adriana Echavarría


2021 ◽  
Vol 97 (4) ◽  
Author(s):  
Rute Ferreira ◽  
Rui Amado ◽  
Jorge Padrão ◽  
Vânia Ferreira ◽  
Nicolina M Dias ◽  
...  

ABSTRACT Bacteriophages (phages) are ubiquitous entities present in every conceivable habitat as a result of their bacterial parasitism. Their prevalence and impact in the ecology of bacterial communities and their ability to control pathogens make their characterization essential, particularly of new phages, improving knowledge and potential application. The isolation and characterization of a new lytic phage against Sphaerotilus natans strain DSM 6575, named vB_SnaP-R1 (SnaR1), is here described. Besides being the first sequenced genome of a Sphaerotilus natans infecting phage, 99% of its 41507 bp genome lacks homology with any other sequenced phage, revealing its uniqueness and previous lack of knowledge. Moreover, SnaR1 is the first Podoviridae phage described infecting this bacterium. Sphaerotilus natans is an important filamentous bacterium due to its deleterious effect on wastewater treatment plants (WWTP) and thus, phages may play a role as novel biotechnological tools against filamentous overgrowth in WWTP. The lytic spectrum of SnaR1 was restricted to its host strain, infecting only one out of three S. natans strains and infection assays revealed its ability to reduce bacterial loads. Results suggest SnaR1 as the prototype of a new phage genus and demonstrates its potential as a non-chemical alternative to reduce S. natans DSM 6575 cells.



2011 ◽  
Vol 85 (1) ◽  
pp. 157-163 ◽  
Author(s):  
Mahendra K. Shukla ◽  
Manoj Kumar ◽  
Kamlesh Prasad ◽  
C.R.K. Reddy ◽  
Bhavanath Jha


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