scholarly journals Clinical statistics of malignant tumors in the oral and maxillofacial regions over the past 10 years.

1993 ◽  
Vol 5 (1) ◽  
pp. 60-69
Author(s):  
Hirotoshi Nakagawa ◽  
Jun-ichiro Toyota ◽  
Eiro Kubota ◽  
Masaaki Goto ◽  
Takeshi Katsuki
Keyword(s):  
Malignant Tumors ◽  
The Past ◽  
Clinical Statistics ◽  
Oral And Maxillofacial Regions

Penile Lymphoepithelioma-Like Carcinoma: A Rare Case With PD-L1 Expression

2021 ◽  
pp. 106689692098834
Author(s):  
Raquel Machado-Neves ◽  
Bernardo Teixeira ◽  
Elsa Fonseca ◽  
Pedro Valente ◽  
Joaquim Lindoro ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Tumor Cells ◽  
Rare Case ◽  
Malignant Tumors ◽  
Squamous Cell Carcinomas ◽  
The Third ◽  
The Past ◽  
First Case ◽  
Lymphoplasmacytic Infiltrate

Most malignant tumors of the penis are squamous cell carcinomas (SCC), being divided in 2 groups, one human papillomavirus (HPV)-related and another non-HPV-related, with lymphoepithelioma-like carcinoma (LELC) being one of the rarest HPV-related SCC. In this article, we report a case of a 50-year-old man who presented testicular swelling and pain for the past 3 months. A penile mass was identified, and the patient was submitted to a total penectomy. The penectomy specimen showed an ulcerated lesion at the glans reaching the cavernous bodies. Microscopic examination showed undifferentiated epithelial cells with syncytial growth pattern mix with a dense lymphoplasmacytic infiltrate, consistent with LELC. The tumor cells expressed p16 and all 3 different clones of PDL1 (22C3, SP263, and SP142). The patient is alive and well with a follow-up of 3 months. To our knowledge, this is the third LELC of the penis reported in literature and the first case reported with PDL1 expression.

scholarly journals Radiation therapy for oligometastatic cancer

2021 ◽  
Vol 10 (3) ◽  
pp. 5-14
Author(s):  
N.  V. Dengina ◽  
T. V. Mitin ◽  
I.  V. Tsimafeyeu ◽  
S.  V. Usychkin
Keyword(s):  
Radiation Therapy ◽  
Cancer Patients ◽  
Primary Tumor ◽  
Malignant Tumors ◽  
Local Treatment ◽  
Supportive Therapy ◽  
Local Method ◽  
The Past ◽  
Oligometastatic Cancer

Current approaches to the treatment of patients with metastatic malignant tumors have changed significantly over the past decade. Instead of a purely palliative systemic or just supportive therapy, a large proportion of patients receive an aggressive local treatment directed not only to the primary tumor, but also to metastatic foci, and a number of studies demonstrate the advantage of such approach. This review provides information on the role of radiation therapy as a local method of treatment of cancer patients with oligometastases.

A Review of the Histopathology of Cigarette Smoke–Induced Lung Cancer in Rats and Mice

2007 ◽  
Vol 26 (4) ◽  
pp. 307-313 ◽  
Author(s):  
Fletcher F. Hahn ◽  
Andrew P. Gigliotti ◽  
Julie A. Hutt ◽  
Thomas H. March ◽  
Joe L. Mauderly
Keyword(s):  
Lung Cancer ◽  
Cigarette Smoke ◽  
Malignant Tumors ◽  
Lung Tumors ◽  
The Past ◽  
Lifetime Exposure ◽  
Low Incidence ◽  
Epithelial Lesions ◽  
Induced Changes ◽  
Rats And Mice

In the past several years an increased number of lung tumors has been reported in laboratory studies of rats and mice after lifetime exposure to mainstream cigarette smoke. Proliferative epithelial lesions are present in the lungs of both species and are apparent antecedent lesions to benign and malignant tumors. Both species have alveolar epithelia hyperplasia, alveolar adenomas, and alveolar carcinomas. The incidence of all three are more in the rats. In addition, mice also have bronchiolar epithelial hyperplasia and bronchial papillomas not found in rats. Rats have a low incidence of squamous cyst that is not found in mice. Lung tumors in rats and mice are found at the end of the life span and rarely metastasize. The characteristics of the lung tumors, and the proliferative changes associated with the tumors, are important in helping understand the mechanisms of lung cancer induction. These studies in rats and mice allow new approaches to the study of cigarette smoke–induced changes in the lung.

scholarly journals Malignant tumors metastasized to oral and maxillofacial regions from other organs; Report of two cases.

1995 ◽  
Vol 7 (4) ◽  
pp. 363-368 ◽  
Author(s):  
Tatsuo Ito ◽  
Takehisa Yamada ◽  
Yasushi Hayashi ◽  
Iwai Tohnai ◽  
Minoru Ueda ◽  
...  
Keyword(s):  
Malignant Tumors ◽  
Oral And Maxillofacial Regions

scholarly journals Statistics of skin malignant tumors in Juntendo Univ. Urayasu hospital for the past decade.

Skin Cancer ◽  
1997 ◽  
Vol 12 (2) ◽  
pp. 230-235
Author(s):  
Noriko MURAYAMA ◽  
Sumino ABE ◽  
Takashi YOSHIIKE ◽  
Kenji TAKAMORI
Keyword(s):  
Malignant Tumors ◽  
The Past

scholarly journals CLINICOPATHOLOGICAL CHARACTERISTICS OF 888 MALIGNANT TUMORS IN THE ORAL AND MAXILLOFACIAL REGIONS

2002 ◽  
Vol 28 (1) ◽  
pp. 47-51
Author(s):  
Yukie KIDO ◽  
Makoto NOGUCHI ◽  
Akihiro MIYAZAKI ◽  
Hisanori KINJO ◽  
Itaru NAGAI ◽  
...  
Keyword(s):  
Malignant Tumors ◽  
Clinicopathological Characteristics ◽  
Oral And Maxillofacial Regions

scholarly journals A 10-year retrospective study of malignant tumors in the oral and maxillofacial regions.

2002 ◽  
Vol 14 (2) ◽  
pp. 37-43
Author(s):  
Ryoko Ukon ◽  
Yoshio Yamashita ◽  
Masaaki Goto ◽  
Koichiro Ihara ◽  
Takeshi Katsuki
Keyword(s):  
Retrospective Study ◽  
Malignant Tumors ◽  
Oral And Maxillofacial Regions

scholarly journals Molecular markers as risk factors for thyroid cancer

2019 ◽  
Vol 91 (10) ◽  
pp. 119-123
Author(s):  
M O Rogova ◽  
S V Novosad ◽  
N S Martirosian ◽  
L V Trukhina ◽  
N A Petunina
Keyword(s):  
Thyroid Cancer ◽  
Thyroid Nodules ◽  
Malignant Tumors ◽  
Molecular Genetic ◽  
Endocrine System ◽  
Diagnostic Value ◽  
Needle Aspiration ◽  
Molecular Genetic Testing ◽  
Papillary Cancer ◽  
The Past

Thyroid cancer is the most common malignant tumor of the endocrine system. An increase in the incidence of thyroid cancer has been noted over the past decade, mainly due to papillary cancer. The influence of environmental factors, increased availability of medical care, including sensitive diagnostic tests, such as ultrasound and fine - needle aspiration (FNA), can affect the fact of the growth of this incidence. Palpation of thyroid gland has very low diagnostic value for detecting thyroid cancer, while thyroid ultrasound and FNA can detect malignant tumors in 20% of cases. Today, the FNA is the fastest, most accurate, economically accessible, and quite safe method for cytological diagnosis of the thyroid nodules. And molecular genetic testing of FNA samples could serve as an additional reliable diagnostic tool in the case of atypia of undetermined significance.

scholarly journals NFIB-Mediated lncRNA PVT1 Aggravates Laryngeal Squamous Cell Carcinoma Progression via the miR-1301-3p/MBNL1 Axis

2021 ◽  
Vol 2021 ◽  
pp. 1-17
Author(s):  
Tian Tang ◽  
Feng Zeng
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Molecular Mechanisms ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Malignant Tumors ◽  
Basic Research ◽  
World Health ◽  
The Past ◽  
Therapy Strategies

Laryngeal squamous cell carcinoma (LSCC) is one of the most common malignant tumors of head and neck cancers. In the past decades, although the therapy strategies of LSCC have made considerable improvement, the terrible outcomes of LSCC still bring an enormous burden to the world health care system. Novel therapeutic targets for LSCC are urgently needed. lncRNAs exert important roles in various biological progressions, including LSCC. Here, we aimed to investigate the function of lncRNA PVT1 in LSCC progression and its underlying molecular mechanisms. By conducting multiple experiments, our results showed that lncRNA PVT1 was upregulated in LSCC cell lines and regulated LSCC cell proliferation, apoptosis, and its cell susceptibility to natural killer (NK) cells. Moreover, it was found that lncRNA PVT1 promotes MBNL1 expression to regulate LSCC cellular progression through sponging miR-1301-3p. Our study might provide novel targets for LSCC basic research or clinical management.

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