Carcinoid Tumors of the Urinary Tract and Prostate

2006 ◽  
Vol 130 (11) ◽  
pp. 1693-1706 ◽  
Author(s):  
Rajmohan Murali ◽  
Kenneth Kneale ◽  
Nestor Lalak ◽  
Warick Delprado

Abstract Context.—Carcinoid tumors are exceedingly rare in the genitourinary tract and may occur in the kidney, urinary bladder, urethra, or prostate. Objective.—To review the clinical and pathologic features of carcinoid tumors occurring in the urinary tract and prostate. Data Sources.—We searched the English language literature using MEDLINE and Ovid. Conclusions.—Carcinoid tumors of the urinary tract and prostate share similar morphologic features with their counterparts in other organs. The differential diagnosis includes metastatic carcinoid tumor, paraganglioma, and nested variants of urothelial and prostatic carcinomas. Correlation of the clinical presentation and histopathologic features (including the immunohistochemical profile) will ensure accurate diagnosis of these rare tumors.

2019 ◽  
Vol 144 (1) ◽  
pp. 15-17 ◽  
Author(s):  
Youssef Al Hmada ◽  
Anas Bernieh ◽  
Robert W. Morris ◽  
Jack Lewin ◽  
Timothy Allen

Context.— Chondroblastoma-like osteosarcoma is an exceedingly rare variant of osteosarcoma, with 22 cases reported in the English-language literature. The tumor is slightly more common in males, with a broad age range (from childhood to elderly). The most commonly involved bones are the metatarsus and tibia, followed by the femur. Most tumors have malignant or worrisome radiographic findings. Prognosis is variable, depending on the presence or absence of lung metastases, local recurrence, and probably tumor location. Histologically, chondroblastoma-like osteosarcoma is characterized by monotonous, minimally to moderately atypical rounded cells with ovoid nuclei resembling chondroblastoma, and abnormal osteoid deposition with destruction of the bone. Objective.— To review the clinical, radiographic, and histopathologic features of chondroblastoma-like osteosarcoma. Data Sources.— PubMed-published chondroblastoma-like osteosarcoma cases in the English-language literature. Conclusions.— Although exceedingly rare, chondroblastoma-like osteosarcoma should be considered in the differential diagnosis of chondroblastoma, especially in the presence of radiologic findings suggestive of an aggressive lesion.


1993 ◽  
Vol 27 (2) ◽  
pp. 167-170 ◽  
Author(s):  
Karen A. Pallone ◽  
Morton P. Goldman ◽  
Matthew A. Fuller

Objective To describe a case of isoniazid-associated psychosis and review the incidence of this adverse effect. Data Sources Information about the patient was obtained from the medical chart. A MEDLINE search of the English-language literature published from 1950 to 1992 was conducted and Index Medicus was manually searched for current information. Study Selection All case reports describing isoniazid-associated psychosis were reviewed. Data Extraction Studies were evaluated for the use of isoniazid, symptoms of psychosis, onset of symptoms, and dosage of isoniazid. Data Synthesis The case report is compared with others reported in the literature. The incidence of isoniazid-associated psychosis is rare. Conclusions The mechanism of isoniazid-associated psychosis is uncertain. It appears that isoniazid was associated with the psychosis evident in our patient and in the cases reviewed.


2010 ◽  
Vol 89 (11) ◽  
pp. E1-E3 ◽  
Author(s):  
Yadiel A. Alameda ◽  
Carlos Perez-Mitchell ◽  
José M. Busquets

We describe the case of a 65-year-old woman who presented with left nasal obstruction. Clinical and radiographic examinations revealed the presence of a soft-tissue mass that had obliterated the left nasal cavity. The mass was completely excised via an endoscopic approach. Histopathologic examination identified the tumor as an ossifying fibrosarcoma. The patient recovered uneventfully and remained free of disease at the 2-year postoperative follow-up. To the best of our knowledge, no case of an ossifying fibrosarcoma of the nasal cavity has been previously reported in the English-language literature. We discuss the features of this case and the clinical presentation, diagnosis, and management of fibrosarcomas of the nasal cavity and paranasal sinuses.


2015 ◽  
Vol 139 (1) ◽  
pp. 83-105 ◽  
Author(s):  
Tammie Ferringer

Context Immunohistochemistry is not a diagnostic test but a highly valuable tool that requires interpretation within a context. Objective To review the current status and limitations of immunohistochemistry in dermatopathology. Data Sources English-language literature published between 1980 and 2014. Conclusions Although immunohistochemistry is rarely completely specific or sensitive, it is an important adjunctive technique in dermatopathology and can be helpful in a series of diagnostic dilemmas.


1997 ◽  
Vol 106 (3) ◽  
pp. 254-260 ◽  
Author(s):  
Kenneth O. Devaney ◽  
Alfio Ferlito

Yolk sac tumors (or endodermal sinus tumors) are rare neoplasms of germ cell origin that have been reported in gonadal sites (testis and ovary). Extragonadal yolk sac tumors are uncommonly seen, and in particular, they are rare in the extracranial head and neck regions; we found 27 well-documented cases in the English-language literature. We discuss their clinical and pathologic features.


2002 ◽  
Vol 126 (3) ◽  
pp. 320-324
Author(s):  
Nicanor I. Moldovan ◽  
Mauro Ferrari

Abstract Context.—Due to its anticipated curative potential, therapeutic angiogenesis recently became a major preoccupation for the biomedical research community. Most of the related work reported to date employs either biochemical or genetic tools. Objective.—To identify opportunities for application of the current developments in microtechnology and nanotechnology to the field of therapeutic angiogenesis. Data Sources.—Survey of recent English-language literature on microvascular tissue engineering in the context of therapeutic angiogenesis. We include our results regarding the role played by microtopographical cues in the progression of angiogenesis, such as those produced during processing of the extracellular matrix by chronic inflammatory cells. Conclusion.—While notable accomplishments have been identified in the field of tissue engineering of larger vessels, reports on purposeful assembly of microvascular structures with the ability to be transferred in vivo by implantation are still scarce. Under these circumstances, we suggest the development of a new class of implantable biomedical microdevices, that is, “angiogenesis assist devices” (or “angiochips”), and we indicate some of their conceivable applications.


2009 ◽  
Vol 133 (7) ◽  
pp. 1087-1095 ◽  
Author(s):  
Amy E. Noffsinger

Abstract Context.—Esophagitis is a common cause of symptoms for which patients seek the advice of a physician. Esophagitis of differing etiologies often demonstrate overlapping histopathologic features, making their distinction difficult. This is especially true in esophageal disorders associated with increased numbers of intraepithelial eosinophils, some of which have just recently been recognized. Objective.—This review discusses the important clinical and pathologic features of the 2 most common disorders associated with esophageal eosinophilic infiltrates—reflux esophagitis and eosinophilic esophagitis—with special emphasis on features that allow the surgical pathologist to distinguish between these disorders. The various forms of drug-induced esophagitis are also discussed because these are frequently underrecognized by pathologists. Data Sources.—Data were extracted from articles identified through PubMed-based research. Histologic figures have been taken from the personal case collection of the author. Conclusions.—Reflux and eosinophilic esophagitis demonstrate overlapping histologic features, which may make their distinction difficult. Drug-induced esophagitis is probably a common phenomenon but is underrecognized by pathologists.


Neurosurgery ◽  
2005 ◽  
Vol 56 (4) ◽  
pp. E871-E871 ◽  
Author(s):  
B Sanjay Harhangi ◽  
Tomas Menovsky ◽  
Hans A.L. Wurzer

Abstract OBJECTIVE AND IMPORTANCE: Anterior cervical discectomy is one of the most frequently performed surgical procedures of the cervical spine. CLINICAL PRESENTATION: We describe a patient with a postoperative hemothorax as a complication after an anterior cervical discectomy. INTERVENTION: The patient was intubated, and reoperation and bronchoscopy were performed. CONCLUSION: To the best of our knowledge, such a complication has not been described before in the English-language literature. We conclude that hemothorax is a rare, although serious, complication after anterior cervical discectomy and should be included in the differential diagnosis for patients with respiratory failure after an anterior cervical discectomy.


1990 ◽  
Vol 104 (12) ◽  
pp. 991-994 ◽  
Author(s):  
Mordechai Kraus ◽  
Dan M. Fliss ◽  
Shmuel Argov ◽  
Alberto Leiberman ◽  
Daniel Benharroch

AbstractA case of Burkitt's lymphoma involving the tonsil in a 10-year-old Bedouin boy, is presented. The biological behaviour and the clinical presentation of this unusual neoplasm are discussed and the English language literature is reviewed.The diagnosis was made by histological examination, electron microscopy and confirmed by immunohistochemistry. The patient showed an excellent symptomatic response to surgery and chemotherapy.


1995 ◽  
Vol 104 (10) ◽  
pp. 808-811 ◽  
Author(s):  
Donald A. Maschka ◽  
John E. Clemons ◽  
John F. Janis

Congenital midline cervical cleft is a rare disorder with a wide range of presentations. To date, there have been fewer than 35 cases reported in the English-language literature. A rarer finding is the association of bronchogenic cysts or respiratory epithelium with the midline cleft. The clinical presentation of congenital midline cervical cleft with a cephalic skin tab, atrophic cleft, and caudal sinus may distinguish it from other conditions of the midline neck. We present an 18-month-old girl with congenital midline cervical cleft to illustrate its clinical presentation and the proper treatment of this condition.


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