scholarly journals Nonlymphoid Hematopoietic Diseases Presenting in Bone, Soft Tissue, and Other Extranodal Sites

2021 ◽  
Author(s):  
Daniel P. Cassidy ◽  
Andrew E. Rosenberg ◽  
Julio Poveda ◽  
Jaylou Velez-Torres ◽  
Jennifer Chapman
Keyword(s):  
Dendritic Cell ◽  
Soft Tissue ◽  
Musculoskeletal System ◽  
Initial Presentation ◽  
Data Sources ◽  
Benign Neoplasms ◽  
Delay In Diagnosis ◽  
Myeloid Neoplasms ◽  
Diagnostic Pitfalls ◽  
Reactive Processes

Context.— Although rare in everyday practice, the initial presentation of hematopoietic neoplasms other than lymphoma in the musculoskeletal system and other extranodal sites can generate challenging diagnostic problems for surgical pathologists. Objective.— To review the morphologic and immunophenotypic features of various nonlymphoid hematopoietic diseases presenting at extranodal sites, with emphasis on the inherent diagnostic pitfalls and differential diagnoses of these entities to aid surgical pathologists in their accurate recognition. Data Sources.— Cases reviewed herein represent both in-house and consult cases seen at our institution between 2010 and 2021. Conclusions.— Entities that present in this way include myeloid neoplasms and histiocytic/dendritic cell neoplasms. These tumors commonly cause nonspecific symptoms, and their histologic appearance can overlap with a variety of benign neoplasms and reactive processes. This can lead to delay in diagnosis and intervention with potentially lifesaving therapy; thus, accurate and expedient recognition is of paramount importance.

scholarly journals Promoting musculoskeletal system soft tissue regeneration by biomaterial-mediated modulation of macrophage polarization

2021 ◽  
Vol 6 (11) ◽  
pp. 4096-4109
Author(s):  
Jinchun Ye ◽  
Chang Xie ◽  
Canlong Wang ◽  
Jiayun Huang ◽  
Zi Yin ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Tissue Regeneration ◽  
Musculoskeletal System ◽  
Macrophage Polarization ◽  
Soft Tissue Regeneration

scholarly journals Subungual Glomus Tumor- Clinical Presentation And Treatment

2014 ◽  
Vol 3 (2) ◽  
pp. 45-48 ◽  
Author(s):  
Shyamal Chandra Debnath ◽  
Suman Kumar Roy ◽  
RR Kairy
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumor ◽  
Clinical Presentation ◽  
Glomus Tumor ◽  
Rare Condition ◽  
Surgical Excision ◽  
Tissue Mass ◽  
Delay In Diagnosis ◽  
Nail Deformity

Glomus tumor is a rare condition and constitutes only 1 % of all soft tissue tumor of body. Glomus tumor is familiar for its unusual presentation and long standing symptoms due to delay in diagnosis. Authors have presented the clinical behavior and treatment of 7 patients with subungual soft tissue mass. Following surgical excision, all patients cured of symptoms, at the end of follow up, no recurrence occurred; post operative nail deformity was insignificant. DOI: http://dx.doi.org/10.3329/bdjps.v3i2.18250 Bangladesh Journal of Plastic Surgery July 2012, 3(2): 45-48

scholarly journals Rotator Cuff Tendinosis in an Animal Model: The Role of Extrinsic and Overuse Factors

2000 ◽  
Author(s):  
S. Thomopoulos ◽  
A. Esmail ◽  
J. D. Williamson ◽  
C. L. Flanagan ◽  
J. P. Iannotti ◽  
...  
Keyword(s):  
Animal Model ◽  
Soft Tissue ◽  
Rotator Cuff ◽  
Musculoskeletal System ◽  
Soft Tissue Injuries ◽  
Rotator Cuff Disease ◽  
Extrinsic Compression ◽  
In Vivo Animal Model

Abstract One of the most common soft tissue injuries of the musculoskeletal system is injury to the rotator cuff tendons of the shoulder. These injuries are commonly attributed to factors such as overuse activity and extrinsic compression. Previous studies on the rotator cuff have been based on surgical reconstructive or clinical retrospective standpoints and were not designed to test hypotheses related to the causes of rotator cuff tendinosis. Our previous study has identified the rat as an appropriate in vivo animal model in which to study rotator cuff disease based on anatomic and functional similarities [1]. The current study uses this animal model to study the roles of extrinsic compression, overuse, and overuse combined with extrinsic compression, on the development of rotator cuff tendinosis. It was hypothesized that a single injury factor would be insufficient to create persistent tendinosis and a combination of injury factors would be necessary.

scholarly journals Rapidly enlarging giant facial mass: initial presentation of blastic plasmacytoid dendritic cell neoplasm

2017 ◽  
Vol 8 (4) ◽  
pp. 453-456
Author(s):  
Gulsen Akoglu ◽  
Sibel Orhun Yavuz ◽  
Aydan Kilicarslan ◽  
Tekin Guney
Keyword(s):  
Dendritic Cell ◽  
Plasmacytoid Dendritic Cell ◽  
Initial Presentation ◽  
Cell Neoplasm

Brain Metastasis in Soft Tissue Sarcoma at Initial Presentation

2021 ◽  
Vol 41 (11) ◽  
pp. 5611-5616
Author(s):  
RYO ITOGA ◽  
MASATAKE MATSUOKA ◽  
TOMOHIRO ONODERA ◽  
ISAO YOKOTA ◽  
KOJI IWASAKI ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Brain Metastasis ◽  
Initial Presentation

Sarcoidosis

2019 ◽  
pp. 233-235
Author(s):  
Kevin B. Hoover
Keyword(s):  
Soft Tissue ◽  
Lymph Nodes ◽  
Metastatic Disease ◽  
Musculoskeletal System ◽  
Systemic Disease ◽  
Primary Treatment ◽  
Tissue Sampling ◽  
Systemic Corticosteroids ◽  
Organ Systems ◽  
Radiographic Changes

Chapter 50 discusses sarcoidosis, which is a systemic disease that often involves the musculoskeletal system. The radiographic changes seen in sarcoid of the phalanges are characteristic, however, involvement of bone and other tissues may be occult or nonspecific. Tissue sampling is often required for diagnosis, especially when sarcoid resembles metastatic disease. The organ systems most commonly involved in sarcoid are the lungs, lymph nodes, skin and eyes. Radiographs are the standard first study used to evaluate symptomatic hand or foot involvement. Uncommon, palpable soft tissue lesions are best evaluated by MRI. Systemic corticosteroids are the primary treatment of active sarcoidosis.

Forearm, hand, and wrist

2013 ◽  
pp. 1314-1322
Author(s):  
Karen Walker-Bone ◽  
Benjamin Ellis
Keyword(s):  
Rheumatoid Arthritis ◽  
Carpal Tunnel Syndrome ◽  
Soft Tissue ◽  
Musculoskeletal System ◽  
Carpal Tunnel ◽  
Diagnostic Tests ◽  
De Quervain’S Disease ◽  
Vital Part ◽  
Tunnel Syndrome ◽  
Forearm Pain

The forearm, hand, and wrist is a functionally vital part of the musculoskeletal system and in consequence, is highly sophisticated and complex in its anatomical development. Frequently, the hand and wrist may be the site of onset of symptoms of a polyarthropathy such as rheumatoid arthritis or of osteoarthritis, so that the physician should always seek to screen for such conditions before making a local diagnosis. Tenosynovitis, de Quervain’s disease, trigger digit, Dupuytren’s, and carpal tunnel syndrome are local soft tissue pathologies which can usually be discriminated on clinical grounds with or without the use of simple diagnostic tests and are satisfying to treat for the most part. Non-specific forearm pain is more complex, with much controversy surrounding not only its aetiopathogenesis but also its existence. It can be difficult to diagnose and difficult to treat.

scholarly journals Acute leukemia as the initial presentation of blastic plasmacytoid dendritic cell neoplasm

2020 ◽  
Vol 60 (1) ◽  
Author(s):  
Pedro Miguel Garrido ◽  
Pedro de Vasconcelos Monteiro ◽  
João Borges‐Costa ◽  
Luís Soares‐Almeida ◽  
Paulo Filipe
Keyword(s):  
Dendritic Cell ◽  
Acute Leukemia ◽  
Plasmacytoid Dendritic Cell ◽  
Initial Presentation ◽  
Cell Neoplasm
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