scholarly journals Optimization of laboratory scale production and purification of microcystin-LR from pure cultures of Microcystis aeruginosa

2007 ◽  
Vol 6 (21) ◽  
pp. 2451-2457 ◽  
Author(s):  
R R Phelan ◽  
T G Downing
Keyword(s):  
Microcystis Aeruginosa ◽  
Laboratory Scale ◽  
Scale Production ◽  
Pure Cultures

scholarly journals Bioreactor Operating Strategies for Improved Polyhydroxyalkanoate (PHA) Productivity

Polymers ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 1197 ◽  
Author(s):  
Warren Blunt ◽  
David Levin ◽  
Nazim Cicek
Keyword(s):  
Production Costs ◽  
Scale Production ◽  
Fed Batch ◽  
Continuous Bioreactor ◽  
Carbon Substrates ◽  
Pure Cultures ◽  
High Production ◽  
Operating Strategies ◽  
Major Factors ◽  
Industrial Scale Production

Microbial polyhydroxyalkanoates (PHAs) are promising biodegradable polymers that may alleviate some of the environmental burden of petroleum-derived polymers. The requirements for carbon substrates and energy for bioreactor operations are major factors contributing to the high production costs and environmental impact of PHAs. Improving the process productivity is an important aspect of cost reduction, which has been attempted using a variety of fed-batch, continuous, and semi-continuous bioreactor systems, with variable results. The purpose of this review is to summarize the bioreactor operations targeting high PHA productivity using pure cultures. The highest volumetric PHA productivity was reported more than 20 years ago for poly(3-hydroxybutryate) (PHB) production from sucrose (5.1 g L−1 h−1). In the time since, similar results have not been achieved on a scale of more than 100 L. More recently, a number fed-batch and semi-continuous (cyclic) bioreactor operation strategies have reported reasonably high productivities (1 g L−1 h−1 to 2 g L−1 h−1) under more realistic conditions for pilot or industrial-scale production, including the utilization of lower-cost waste carbon substrates and atmospheric air as the aeration medium, as well as cultivation under non-sterile conditions. Little development has occurred in the area of fully continuously fed bioreactor systems over the last eight years.

Laboratory scale production and evaluation of carbon-carbon

1993 ◽  
pp. 227-276
Author(s):  
G. Savage
Keyword(s):  
Laboratory Scale ◽  
Scale Production

scholarly journals Injection Moulding of Oxide Ceramic Matrix Composites: Comparing Two Feedstocks

2019 ◽  
Vol 809 ◽  
pp. 140-147 ◽  
Author(s):  
Maike Böttcher ◽  
Daisy Nestler ◽  
Jonas Stiller ◽  
Lothar Kroll
Keyword(s):  
High Temperature ◽  
Injection Moulding ◽  
Ceramic Matrix ◽  
Ceramic Composites ◽  
Laboratory Scale ◽  
Oxide Ceramic ◽  
Scale Production ◽  
Oxide Ceramics ◽  
Moulding Process ◽  
Injection Moulding Process

Ceramic materials are suitable for use in the high temperature range. Oxide ceramics, in particular, have a high potential for long-term applications under thermal cycling and oxidising atmosphere. However, monolithic oxide ceramics are unsuitable for use in high-temperature technical applications because of their brittleness. Thin-walled, oxidation resistant, and high-temperature resistant materials can be developed by reinforcing oxide ceramics with ceramic fibres such as alumina fibres. The increase of the mechanical stability of the composites in comparison to the non-fibre reinforced material is of outstanding importance. Possible stresses or cracks can be derived along the fibre under mechanical stress or deformation. Components made of fibre-reinforced ceramic composites with oxide ceramic matrix (OCMC) are currently produced in manual and price-intensive processes for small series. Therefore, the manufacturing should be improved. The ceramic injection moulding (CIM) process is established in the production of monolithic oxide ceramics. This process is characterised by its excellent automation capability. In order to realise large scale production, the CIM-process should be transferred to the production of fibre-reinforced oxide ceramics. The CIM-process enables the production of complicated component shapes and contours without the need for complex mechanical post-treatment. This means that components with complex geometries can be manufactured in large quantities.To investigate the suitability of the injection moulding process for the production of OCMCs, two different feedstocks and alumina fibres (Nextel 610) were compounded in a laboratory-scale compounder. The fibre volume fractions were varied. In a laboratory-scale injection moulding device, microbending specimens were produced from the compounds obtained in this way. To characterise the test specimens, microstructure examinations and mechanical-static tests were done. It is shown that the injection moulding process is suitable for the production of fibre-reinforced oxide ceramics. The investigations show that the feedstocks used have potential for further research work and for future applications as material components for high-temperature applications in oxidising atmospheres.

Efficient laboratory-scale production of monoclonal antibodies using membrane-based high-density cell culture technology

1999 ◽  
Vol 230 (1-2) ◽  
pp. 59-70 ◽  
Author(s):  
Mohamed Trebak ◽  
Jae Min Chong ◽  
Dorothee Herlyn ◽  
David W Speicher
Keyword(s):  
Cell Culture ◽  
Monoclonal Antibodies ◽  
High Density ◽  
Laboratory Scale ◽  
Scale Production ◽  
High Density Cell ◽  
High Density Cell Culture ◽  
Culture Technology

Laboratory-scale production and purification of the iron chelator rhizoferrin: a novel Fe supplier to plants

2017 ◽  
pp. 1-9 ◽  
Author(s):  
Chana Frenkel ◽  
Yitzhak Hadar ◽  
Yona Chen
Keyword(s):  
Iron Chelator ◽  
Laboratory Scale ◽  
Scale Production

Effects of Larval Stocking Density on Laboratory-Scale and Commercial-Scale Production of Summer Flounder Paraliehthys dentatus

2007 ◽  
Vol 31 (3) ◽  
pp. 436-445 ◽  
Author(s):  
Nicholas J. King ◽  
W. Huntting Howell ◽  
Marina Huber ◽  
David A. Bengtson
Keyword(s):  
Stocking Density ◽  
Laboratory Scale ◽  
Scale Production ◽  
Summer Flounder ◽  
Commercial Scale

scholarly journals An Optimization Study for Laboratory Scale Production of Glucose Syrup from Potato, Wheat and Maize Starch

2021 ◽  
pp. 364-372
Author(s):  
Emine KAPAR YILMAZ ◽  
Ali AKBAYRAK ◽  
Ceren BAYRAÇ
Keyword(s):  
Laboratory Scale ◽  
Scale Production ◽  
Maize Starch ◽  
Optimization Study ◽  
Glucose Syrup

scholarly journals Laboratory‐Scale Production of Tomato Carotenoids Using Bioengineered Escherichia coli

2011 ◽  
Vol 25 (S1) ◽  
Author(s):  
Chi‐Hua (Peter) Lu ◽  
Jin‐Ho Choi ◽  
Yong‐Su Jin ◽  
John W. Erdman
Keyword(s):  
Escherichia Coli ◽  
Laboratory Scale ◽  
Scale Production

scholarly journals Effects of different culture media on physiological features and laboratory scale production cost of Dunaliella salina

2020 ◽  
Vol 27 ◽  
pp. e00508
Author(s):  
Guilherme Augusto Colusse ◽  
Carlos Rafael Borges Mendes ◽  
Maria Eugênia Rabello Duarte ◽  
Julio Cesar de Carvalho ◽  
Miguel Daniel Noseda
Keyword(s):  
Production Cost ◽  
Dunaliella Salina ◽  
Culture Media ◽  
Laboratory Scale ◽  
Scale Production
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