Comparative Assessment of Biochemical Alterations after Epidural Administration of Ropivacaine and Ropivacaine-Dexmedetomidine Combination as an Epidural Analgesia in Buffalo Calves

2016 ◽  
Vol 18 (1) ◽  
pp. 63 ◽  
Author(s):  
Shweta Kamble ◽  
R. Jain ◽  
B.P. Shukla ◽  
S.S. Pandey ◽  
N. Rajput ◽  
...  
Author(s):  
A. Jaiswal ◽  
S. S. Pandey ◽  
A. S. Parihar ◽  
N. Rajput ◽  
R. Jain

The study was conducted on 12 healthy male buffalo calves weighing between 50 to 60 Kg to evaluate haemato-biochemical alterations after epidural injection of dexmedetomidine alone and in combination with bupivacaine. Haematological examination showed nonsignificant alterations. Biochemical examination showed significant increase in blood glucose, blood urea nitrogen and serum creatinine while there was nonsignificant alterations in total protein and alkaline phosphatase. All haemato-biochemical changes were transient and compensatory.


2012 ◽  
Vol 21 (1) ◽  
pp. 24-35 ◽  
Author(s):  
Ryoko Hidaka ◽  
Lynn Clark Callister

The purpose of our qualitative descriptive study was to describe the birth experiences of women using epidural analgesia for pain management. We interviewed nine primiparas who experienced vaginal births. Five themes emerged: (a) coping with pain, (b) finding epidural administration uneventful, (c) feeling relief having an epidural, (d) experiencing joy, and (e) having unsettled feelings of ambivalence. Although epidural analgesia was found to be effective for pain relief and may contribute to some women’s satisfaction with the birth experience, it does not guarantee a quality birth experience. In order to support and promote childbearing women’s decision making, we recommend improved education on the variety of available pain management options, including their risks and benefits. Fostering a sense of caring, connection, and control in women is a key factor to ensure positive birth experiences, regardless of pain management method.


Author(s):  
E. Yu Syrchin ◽  
R. E Lakhin ◽  
E. M Davletshina ◽  
A. A Grazhdankin

Background. Anesthetic management of patients with morbid obesity during bariatric surgery presents a number of problems, including difficult" vascular access, difficult" airways, increased risk of aspiration, changes in the pharmacokinetics of anesthetics, and an increased risk of postoperative respiratory depression associated with opioids. Methods. Case description Patient 32 years old, height 162 cm, body weight 200 kg (body mass index 76.2 kg/ m2) underwent surgical treatment for morbid obesity (gastroentero bypass) using combined anesthesia (general anesthesia with desflurane combined with epidural analgesia ropivacaine 2 mg/ml). Results. Ultrasound navigation was used to catheterize the peripheral vein and insert an epidural catheter. Also, due to the high risk of difficult airways (according to the MOSCOW TD scale - 4 points), the patient underwent fiberoptic orotracheal intubation with in consciousness with sedation by dexmedetomidine to level -1 on the Richmond excitation-sedation scale. Early activation of the patient was achieved by controlled anesthesia and multimodal analgesia in the postoperative period. Analgesia after surgery using prolonged epidural administration of 0.2 % ropivacaine at a rate of 4-8 ml/h, intravenous paracetamol 1 gram every 8 hours. 2 hours after the end of the operation, the patient sat down on the bed with her legs down and got up for the first time after 6 hours. On the second day, she was transferred to a specialized department with prolonged epidural analgesia, the duration of which was 72 hours. Complications were not observed in the postoperative period. The patient was discharged from the clinic on the eighth day after surgery in a satisfactory condition without active complaints. Conclusion. In this clinical case, the chosen tactics of postoperative analgesia made it possible to achieve good analgesia, conduct early activation of the patient, and begin early rehabilitation procedures.


2003 ◽  
Vol 11 (1) ◽  
pp. 67-72 ◽  
Author(s):  
RJ Kumar ◽  
KV Menon ◽  
TC Ranjith

Purpose. This is a retrospective study of the role of postoperative epidural analgesia in major spinal surgical procedures. With the number and complexity of the procedures performed on the spine ever-increasing, this method of analgesia is becoming more important. Methods. Results of 74 consecutive cases of major spinal surgeries between January 2000 and January 2001 at the Spine Division, Amritha Institute of Medical Sciences and Research Centre, Kochi, India, were studied. 32 cases were posterior procedures and the other 42 were anterior procedures of the thoracic and lumbar regions. The use of various combinations of local anaesthetic and opioid to control postoperative pain after spinal surgery were analysed. Results. 36 (49%) of 74 patients did not require any parenteral supplements. Of the remaining 38 patients who required supplementary parenteral analgesia in the first 48 hours, 25 (34%) received a single dose and 13 (18%) required more than one dose. The number of patients requiring parenteral analgesia immediately after operation were 11; between 2 and 6 hours were 12; and between 6 and 24 hours were 11. Of the 74 patients, 67 had a sound sleep after epidural administration. There were 2 cases of respiratory depression and 2 of transient hypotension. Conclusion. Most epidural analgesic regimens significantly reduced postoperative pain, and the requirement for supplementary parenteral analgesics was minimal. Adverse effects were rare, yet we recommend that patients treated with this protocol be managed in high-dependency units.


Author(s):  
Sukumar Misra

Abstract: opioids and local anesthetics have been the traditional choice in epidural analgesia. However opioids suffer from the issue of side effects and res piratory depression. The use of newer agent like dexmedetomidine is a viable option. The present study was formulated to provide a comparative assessment of whether fentanyl or dexmedetomidine is a better adjuvant for lower limb surgeries in which epidural route is used. The study included a pool of 30 subjects who were divided in two equal groups and administered fentanyl or dexmedetomidine. The results displayed a shorter duration of sensory block and motor block in dexmedetomidine group as compared to fentanyl. The overall efficacy of dexmedetomidine was better in the present study. Keywords: analgesia, dexmedetomidine, epidural, fentanyl


2017 ◽  
Vol 11 (3) ◽  
pp. 182-188
Author(s):  
K. A Bozhenkov ◽  
T. A Gustovarova ◽  
A. N Ivanyan ◽  
V. L Vinogradov ◽  
E. M Shifman

This paper will be concerned with the results of a prospective controlled longitudinal study which has involved 132 secundiparae (among them 69 patients are with the uterine scar after cesarean section). The parturient women have been divided into 3 groups. Group “A” includes 38 women with the uterine scar after cesarean section, in this group epidural analgesia was administered during vaginal delivery. Group “B” includes 32 secundiparae without uterine scar, in this group epidural analgesia was administered during vaginal delivery. Group “C” - 31 women with the uterine scar, no epidural analgesia was administered during vaginal delivery. Based on a comparative assessment of the pain syndrome intensity in labor according to the visual analogue scale, the research has proved that delivery at the women with the uterine scar is accompanied by statistically more significant pain than at the women without uterine scar. The necessity of analgesia during vaginal delivery at the women with the uterine scar has been proved. The effectiveness and safety of epidural analgesia at patients with the uterine scar have been analyzed. It has been proved that epidural analgesia provides anesthesia during vaginal delivery at the women with the uterine scar, while it does not affect the total duration and course of labor, maternal and perinatal outcomes, and does not mask the clinical picture of the uterine rupture threat.


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