Phytosomes-A Novel Approach in Herbal Drug Delivery System

2018 ◽  
Vol 8 (3) ◽  
pp. 151
Author(s):  
Yogita Rayate ◽  
Shital Shewale ◽  
Aishwarya Patil ◽  
Manojkumar Nitalikar ◽  
Shrinivas Mohite
2016 ◽  
Vol 7 (6) ◽  
pp. 15-21
Author(s):  
R P Singh ◽  
H V Gangadharappa ◽  
K Mruthunjaya

2019 ◽  
Vol 12 (4) ◽  
pp. 1688 ◽  
Author(s):  
B. Senthilnathan ◽  
K. Vivekanandan ◽  
E. Bhavya ◽  
Masilamani ◽  
B. Swarna Priya

2021 ◽  
Vol Volume 15 ◽  
pp. 557-576
Author(s):  
Hua-Feng Yin ◽  
Chun-Ming Yin ◽  
Ting Ouyang ◽  
Shu-Ding Sun ◽  
Wei-Guo Chen ◽  
...  

YMER Digital ◽  
2022 ◽  
Vol 21 (01) ◽  
pp. 41-55
Author(s):  
L Tamilselvi ◽  
◽  
R Senthamarai ◽  
A.M. Ismail ◽  
T Shri Vijaya Kirubha ◽  
...  

Novel herbal drug delivery system opens new vistas for delivery of herbal drugs at right place, at right concentration, for right period of time and also gives scientific angle to verify the standardization of herbal drug. Herbal Transdermal patches can develop valuable assessment and drug safety by additional site specific the way and temporal position in the body’s imperative to reduce the number and size of doses required to achieve the objective of systemic medication during topical application to the intact skin surface. Rheumatoid Arthritis (RA) is a chronic, progressive autoimmune disease of unknown cause. It is characterized by persistent inflammation that primarily affects the peripheral joints. In the present study, herbal transdermal patch was developed by using ethanolic extract of leaves of Cardiospermum halicacabum and rhizomes of Drynaria quercifolia that had already been widely used for the treatment of arthritis in conventional dosage forms. Evaluation of the developed patch for the effectiveness against RA was done by in vitro methods in terms of inhibition of albumin denaturation, measurement of Interleukin-6 cytokines by Enzyme-Linked Immuno Assay (ELISA). IC-50 value was determined from albumin denaturation inhibition assay. The herbal patch significantly and dosedependently inhibited Interleukin–6 cytokines. The present study revealed that the formulated polyherbal Transdermal patch will be the better drug of choice for the treatment of Rheumatoid Arthritis as compared to the conventional dosage forms.


2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Young-Seok Park ◽  
Joo-Youn Cho ◽  
Shin-Jae Lee ◽  
Chee Il Hwang

The aim of this study was to investigate the efficacy of a proposed new implant mediated drug delivery system (IMDDS) in rabbits. The drug delivery system is applied through a modified titanium implant that is configured to be implanted into bone. The implant is hollow and has multiple microholes that can continuously deliver therapeutic agents into the systematic body. To examine the efficacy and feasibility of the IMDDS, we investigated the pharmacokinetic behavior of dexamethasone in plasma after a single dose was delivered via the modified implant placed in the rabbit tibia. After measuring the plasma concentration, the areas under the curve showed that the IMDDS provided a sustained release for a relatively long period. The result suggests that the IMDDS can deliver a sustained release of certain drug components with a high bioavailability. Accordingly, the IMDDS may provide the basis for a novel approach to treating patients with chronic diseases.


2020 ◽  
Vol 11 (1) ◽  
pp. 368-385 ◽  
Author(s):  
Sharadha M ◽  
Gowda D V ◽  
Vishal Gupta N ◽  
Akhila A R

The paper reviews an overview of a conventional and novel approach in the topical drug delivery system. Drug delivery via the skin is becoming progressively popular due to its convenience and affordability. The skin is the most important mechanical barrier to the penetration of many drug substances and acts as an ideal site to deliver the drug both locally and systemically. The topical route has been a favored route of drug administration over the last decades. Despite conventional topical drug delivery systems limits in poor retention and low bioavailability. This drawback overcomes by extensive research to develop a novel topical drug delivery systems targeting to improve the safety, efficacy and to minimize side effects. The conventional review focuses on dusting powders, poultices, plasters, lotion, liniments, solution, emulsion, suspension, colloidions, tinctures, creams, gels, ointments, pastes, suppositories, transdermal delivery systems, tapes, and gauzes and rubbing alcohol while the novel review focuses on novel gels, aerosol foams, microsponges, muco-adhesive bio-adhesives, novel vesicular carriers, nano-emulsion & nano-emulgel, protein and peptide delivery, polymers, emulsifier-free formulations and fullerenes etc. The key purpose of a topical delivery system is to enhance the skin permeability and to retain in the dermis. This review addresses a basis for further advancement and up-gradation of current techniques and technologies.


2018 ◽  
Vol 1 (2) ◽  
pp. 39-48
Author(s):  
Kalpesh C. Ashara ◽  
Jalpa S. Paun ◽  
M. M. Soniwala ◽  
J. R. Chavada ◽  
J. K. Badjatiya

As because of several advantages over to the conventional drug delivery Nanosparticulate drug delivery prepared in several means by several ways of methods have several applications in different discipline of Pharmaceutical science. There are various parameters for Evaluation of Nanoparticles as Drug Delivery system so we can justified as nanoparticulate drug delivery system: a novel approach.


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