scholarly journals Diet and Breast Cancer Risk Reduction

2007 ◽  
Vol 5 (8) ◽  
pp. 809-816 ◽  
Author(s):  
Eleni Linos ◽  
Walter C. Willett
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Dietary Factors ◽  
Future Research ◽  
Healthy Weight ◽  
Cancer Subtypes ◽  
Timing Of Exposure ◽  
Cancer Risk Reduction

The association between diet and breast cancer risk has been investigated extensively and has led to some recommendations for prevention. Research suggests that maintaining a healthy weight may reduce the risk for breast cancer after menopause. Additionally, alcohol increases the risk for breast cancer even at moderate levels of intake, and women who drink alcohol also should take sufficient folate, which can mitigate this excess risk. Interesting questions for future research include the role of soy products, red meat, energy balance, and vitamin D, with particular attention to timing of exposure in early life. Breast cancer is a heterogeneous disease, and dietary factors may differentially affect certain breast cancer subtypes; future studies should therefore attempt to characterize associations according to tumor characteristics.

scholarly journals Deciding on breast cancer risk reduction: The role of counseling in individual decision-making – A qualitative study

2017 ◽  
Vol 100 (12) ◽  
pp. 2346-2354 ◽  
Author(s):  
Sarah B. Blakeslee ◽  
Worta McCaskill-Stevens ◽  
Patricia A. Parker ◽  
Christine M. Gunn ◽  
Hanna Bandos ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Decision Making ◽  
Breast Cancer Risk ◽  
Qualitative Study ◽  
Cancer Risk ◽  
Individual Decision ◽  
Individual Decision Making ◽  
Breast Cancer Risk Reduction ◽  
Cancer Risk Reduction

scholarly journals The role of anthropometric and nutritional factors on breast cancer risk in African-American women

2011 ◽  
Vol 15 (4) ◽  
pp. 738-748 ◽  
Author(s):  
Urmila Chandran ◽  
Kim M Hirshfield ◽  
Elisa V Bandera
Keyword(s):  
Breast Cancer ◽  
Physical Activity ◽  
African American ◽  
Black Women ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
African American Women ◽  
Dietary Factors ◽  
American Women

AbstractObjectiveWhile the role of nutrition, physical activity and body size on breast cancer risk has been extensively investigated, most of these studies were conducted in Caucasian populations. However, there are well-known differences in tumour biology and the prevalence of these factors between African-American and Caucasian women. The objective of the present paper was to conduct a review of the role of dietary factors, anthropometry and physical activity on breast cancer risk in African-American women.DesignTwenty-six research articles that presented risk estimates on these factors in African-American women and five articles involving non-US black women were included in the current review.SettingRacial disparities in the impact of anthropometric and nutritional factors on breast cancer risk.SubjectsAfrican-American and non-US black women.ResultsBased on the few studies that presented findings in African-American women, an inverse association with physical activity was found for pre- and postmenopausal African-American women, while the association for anthropometric and other dietary factors, such as alcohol, was unclear. Studies assessing the effect by molecular subtypes in African-American women were too few and based on sample sizes too small to provide definitive conclusions.ConclusionsThe effect of certain nutrition and lifestyle factors on breast cancer in African-American women is not starkly distinct from those observed in white women. However, there is an enormous need for further research on this minority group to obtain more confirmatory findings.

Prophylactic Mastectomy - Evaluation and Treatment of High Risk Patients

Swiss Surgery ◽  
2002 ◽  
Vol 8 (2) ◽  
pp. 45-52 ◽  
Author(s):  
Remmel ◽  
Harder
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Risk Reduction ◽  
Prophylactic Mastectomy ◽  
Interdisciplinary Approach ◽  
Reconstructive Procedures ◽  
Medline Search ◽  
Breast Cancer Risk Reduction ◽  
Cancer Risk Reduction

Prophylactic mastectomy is an aggressive strategy for breast cancer risk reduction. The indications and efficiency of this procedures are not yet clearly defined. Randomized, prospective studies, comparing different surgical procedures with other modalities of breast cancer risk reduction are lacking. The report evaluates the existing controversy, based on Medline search in the following sequence: risk factors, possibilities of risk reduction, effectiveness of risk reduction, technical considerations and recommendations. Patient selection is difficult and needs an interdisciplinary approach. The women have to be well informed about all treatment alternatives and various reconstructive procedures. An appropriate risk reduction strategy should be selected individually for each patient. Up to now, there exist only recommendations from different institutions but no definitive guidelines.

scholarly journals The association of women’s birth size with risk of molecular breast cancer subtypes: a cohort study

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Marie S. Sandvei ◽  
Signe Opdahl ◽  
Marit Valla ◽  
Pagona Lagiou ◽  
Ellen Veronika Vesterfjell ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Birth Weight ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Head Circumference ◽  
Birth Length ◽  
Birth Size ◽  
Luminal A ◽  
Cancer Subtypes ◽  
Luminal B

Abstract Background Because birth size appears to be positively associated with breast cancer risk, we have studied whether this risk may differ according to molecular breast cancer subtypes. Methods A cohort of 22,931 women born 1920–1966 were followed up for breast cancer occurrence from 1961 to 2012, and 870 were diagnosed during follow-up. Archival diagnostic material from 537 patients was available to determine molecular breast cancer subtype, specified as Luminal A, Luminal B (human epidermal growth factor receptor 2 (HER2)-), Luminal B (HER2+), HER2 type, and Triple negative (TN) breast cancer. Information on the women’s birth weight, birth length and head circumference at birth was used to estimate hazard ratios (HR) with 95% confidence intervals (CI) for each molecular subtype, applying Cox regression, and stratified by maternal height. Results Birth length (per 2 cm increments) was positively associated with Luminal A (HR = 1.2, 95% CI, 1.0–1.3), Luminal B (HER2+) (HR = 1.3, 95% CI, 1.0–1.7), and TN breast cancer (HR = 1.4, 95% CI, 1.0–1.9). No clear association was found for birth weight and head circumference. The positive associations of birth length were restricted to women whose mothers were relatively tall (above population median). Conclusion We found a positive association of birth length with risk of Luminal A, Luminal B (HER2+) and TN breast cancer that appears to be restricted to women whose mothers were relatively tall. This may support the hypothesis that breast cancer risk is influenced by determinants of longitudinal growth and that this finding deserves further scrutiny.

scholarly journals Excess breast cancer risk and the role of parity, age at first childbirth and exposure to radiation in infancy

2001 ◽  
Vol 85 (3) ◽  
pp. 362-366 ◽  
Author(s):  
E Holmberg ◽  
L-E Holm ◽  
M Lundell ◽  
A Mattsson ◽  
A Wallgren ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk
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