On The Effect Of Decomposition Granularity On DeTraC For COVID-19 Detection Using Chest X-Ray Images

Author(s):  
Nicole P. Mugova ◽  
Mohammed M. Abdelsamea ◽  
Mohamed M. Gaber

Covid-19 is a growing issue in society and there is a need for resources to manage the disease. This paper looks at studying the effect of class decomposition in our previously proposed deep Convolutional Neural Network, called DeTraC (Decompose, Transfer and Compose). DeTraC has the ability to robustly detect and predict Covid-19 from chest X-ray images. The experimental results showed that changing the number of clusters affected the performance of DeTraC and influenced the accuracy of the model. As the number of clusters increased, the accuracy decreased for the shallow tuning mode but increased for the deep tuning mode. This shows the importance of using suitable hyperparameter settings in order to get the best results from a deep learning model. The highest accuracy obtained, in this study, was 98.33% from the deep tuning model.

2020 ◽  
Author(s):  
Zicheng Hu ◽  
Alice Tang ◽  
Jaiveer Singh ◽  
Sanchita Bhattacharya ◽  
Atul J. Butte

AbstractCytometry technologies are essential tools for immunology research, providing high-throughput measurements of the immune cells at the single-cell level. Traditional approaches in interpreting and using cytometry measurements include manual or automated gating to identify cell subsets from the cytometry data, providing highly intuitive results but may lead to significant information loss, in that additional details in measured or correlated cell signals might be missed. In this study, we propose and test a deep convolutional neural network for analyzing cytometry data in an end-to-end fashion, allowing a direct association between raw cytometry data and the clinical outcome of interest. Using nine large CyTOF studies from the open-access ImmPort database, we demonstrated that the deep convolutional neural network model can accurately diagnose the latent cytomegalovirus (CMV) in healthy individuals, even when using highly heterogeneous data from different studies. In addition, we developed a permutation-based method for interpreting the deep convolutional neural network model and identified a CD27-CD94+ CD8+ T cell population significantly associated with latent CMV infection. Finally, we provide a tutorial for creating, training and interpreting the tailored deep learning model for cytometry data using Keras and TensorFlow (github.com/hzc363/DeepLearningCyTOF).


Author(s):  
Syed Farhan Hyder Abidi

India accounts for the world’s largest number of cases in TB, with 2.8 million cases annually, and accounts for more than a quarter of the global TB burden. Tuberculosis (TB) is caused by the bacterium (Mycobacterium tuberculosis) which most commonly affects the lungs. TB is transmitted from person to person through the air. When people with TB cough, sneeze or spit, the germs are propelled into the air. This paper showcases a methodology which uses a Deep Learning Model (dCNN) for the detection of Tuberculosis in the lungs. The accuracy obtained by the methods for the model is desirable and dependable, which is increasingly productive in contrast to the accuracy shown by other neural networks.


PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0256500
Author(s):  
Maleika Heenaye-Mamode Khan ◽  
Nazmeen Boodoo-Jahangeer ◽  
Wasiimah Dullull ◽  
Shaista Nathire ◽  
Xiaohong Gao ◽  
...  

The real cause of breast cancer is very challenging to determine and therefore early detection of the disease is necessary for reducing the death rate due to risks of breast cancer. Early detection of cancer boosts increasing the survival chance up to 8%. Primarily, breast images emanating from mammograms, X-Rays or MRI are analyzed by radiologists to detect abnormalities. However, even experienced radiologists face problems in identifying features like micro-calcifications, lumps and masses, leading to high false positive and high false negative. Recent advancement in image processing and deep learning create some hopes in devising more enhanced applications that can be used for the early detection of breast cancer. In this work, we have developed a Deep Convolutional Neural Network (CNN) to segment and classify the various types of breast abnormalities, such as calcifications, masses, asymmetry and carcinomas, unlike existing research work, which mainly classified the cancer into benign and malignant, leading to improved disease management. Firstly, a transfer learning was carried out on our dataset using the pre-trained model ResNet50. Along similar lines, we have developed an enhanced deep learning model, in which learning rate is considered as one of the most important attributes while training the neural network. The learning rate is set adaptively in our proposed model based on changes in error curves during the learning process involved. The proposed deep learning model has achieved a performance of 88% in the classification of these four types of breast cancer abnormalities such as, masses, calcifications, carcinomas and asymmetry mammograms.


2020 ◽  
Vol 117 (35) ◽  
pp. 21373-21380
Author(s):  
Zicheng Hu ◽  
Alice Tang ◽  
Jaiveer Singh ◽  
Sanchita Bhattacharya ◽  
Atul J. Butte

Cytometry technologies are essential tools for immunology research, providing high-throughput measurements of the immune cells at the single-cell level. Existing approaches in interpreting and using cytometry measurements include manual or automated gating to identify cell subsets from the cytometry data, providing highly intuitive results but may lead to significant information loss, in that additional details in measured or correlated cell signals might be missed. In this study, we propose and test a deep convolutional neural network for analyzing cytometry data in an end-to-end fashion, allowing a direct association between raw cytometry data and the clinical outcome of interest. Using nine large cytometry by time-of-flight mass spectrometry or mass cytometry (CyTOF) studies from the open-access ImmPort database, we demonstrated that the deep convolutional neural network model can accurately diagnose the latent cytomegalovirus (CMV) in healthy individuals, even when using highly heterogeneous data from different studies. In addition, we developed a permutation-based method for interpreting the deep convolutional neural network model. We were able to identify a CD27- CD94+ CD8+ T cell population significantly associated with latent CMV infection, confirming the findings in previous studies. Finally, we provide a tutorial for creating, training, and interpreting the tailored deep learning model for cytometry data using Keras and TensorFlow (https://github.com/hzc363/DeepLearningCyTOF).


Author(s):  
R. Rohith ◽  
S.P.Syed Ibrahim

Tuberculosis is a life-threatening disease that mainly affects underdeveloped as well as developing nations. While lethal it is often resistive to antibiotics and the safest way to treat a patient is to detect the disease's presence as soon as possible. Various techniques have been developed to diagnose tuberculosis and radiography of the chest is one of such methods that works well for over a decade.. Though an effective method still the success depends on the medical officer who examines the chest X-rays. Thus ,this paper proposes an approach for detecting X-ray abnormalities using deep learning. The systems output is assessed on two open Montgomery and Shenz en chest X-ray datasets and accuracy of 84 percent is achieved.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Makoto Nishimori ◽  
Kunihiko Kiuchi ◽  
Kunihiro Nishimura ◽  
Kengo Kusano ◽  
Akihiro Yoshida ◽  
...  

AbstractCardiac accessory pathways (APs) in Wolff–Parkinson–White (WPW) syndrome are conventionally diagnosed with decision tree algorithms; however, there are problems with clinical usage. We assessed the efficacy of the artificial intelligence model using electrocardiography (ECG) and chest X-rays to identify the location of APs. We retrospectively used ECG and chest X-rays to analyse 206 patients with WPW syndrome. Each AP location was defined by an electrophysiological study and divided into four classifications. We developed a deep learning model to classify AP locations and compared the accuracy with that of conventional algorithms. Moreover, 1519 chest X-ray samples from other datasets were used for prior learning, and the combined chest X-ray image and ECG data were put into the previous model to evaluate whether the accuracy improved. The convolutional neural network (CNN) model using ECG data was significantly more accurate than the conventional tree algorithm. In the multimodal model, which implemented input from the combined ECG and chest X-ray data, the accuracy was significantly improved. Deep learning with a combination of ECG and chest X-ray data could effectively identify the AP location, which may be a novel deep learning model for a multimodal model.


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