Challenges in the Treatment of Mobility Loss and Walking Impairment in Multiple Sclerosis

2010 ◽  
Vol 12 (1) ◽  
pp. 13-16 ◽  
Author(s):  
June Halper ◽  
Amy Perrin Ross
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Health Care Professionals ◽  
International Organization ◽  
Standards Of Care ◽  
Direct Impact ◽  
Care Partners ◽  
Review Current ◽  
Current Standards

Several recent studies have shown that mobility loss and walking impairment are significant concerns among people living with multiple sclerosis (MS). Ongoing challenges related to the assessment and management of mobility loss can have a direct impact on outcomes and patient quality of life. These challenges are evident across the spectrum of patient experience and at all stages on the treatment continuum. In June 2009 a panel of MS experts met to review current standards of care in the treatment of mobility loss in MS. The objective of the roundtable meeting was to identify specific actions that patients, care partners, and health-care professionals should consider to improve the assessment, diagnosis, and treatment of mobility loss and walking impairment in people with MS. The meeting was hosted by the International Organization of Multiple Sclerosis Nurses and was supported by a grant from Acorda Therapeutics.

Quality of Life for Patients Detained in Hospital

1993 ◽  
Vol 162 (5) ◽  
pp. 611-620 ◽  
Author(s):  
Jeremy W. Coid
Keyword(s):  
Quality Of Life ◽  
Health Care Professionals ◽  
Hospital Staff ◽  
Poor Quality ◽  
Standards Of Care ◽  
Future Research ◽  
High Quality ◽  
Legal Principles ◽  
The Uk

The quality of life of detained patients has not received adequate attention despite the responsibilities placed on hospital staff and the special problems faced by these patients. Legal principles to ensure quality of life have not been formalised, and the acceptable standards that a patient can expect have not been tested in the UK courts. Contemporary models of ensuring quality are being imposed with increasing pressure on health care professionals, but high-quality management has sometimes lagged behind. This has led to a poor quality of life for certain patients. It is important for future research to overcome difficulties in developing objective measurements and set the appropriate standards of quality of life that detained patients should expect. This would provide a basis against which both appropriate standards of care and the necessary resource allocation could be measured.

scholarly journals Measuring quality of life and identifying what is important to Jordanian living with Multiple Sclerosis using the Arabic version of the Patient Generated Index (PGI)

2020 ◽  
Author(s):  
Ala' S. Aburub ◽  
Hanan Khalil ◽  
Alham Al-Sharman ◽  
Khalid El-Salem
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Psychometric Properties ◽  
Health Care Professionals ◽  
Wide Spectrum ◽  
Involuntary Movement ◽  
Arabic Version ◽  
Global Score ◽  
Reaction Functions

Abstract Background Patients Generated index (PGI) is one of the individualized measures used to measure the quality of life (QOL) in people with different chronic conditions including multiple sclerosis (MS). However, the psychometric properties of the Arabic version of the PGI have not been fully established in Jordanian living with MS. Therefore, the objective of this study is to identify what matters to Jordanian living with MS and to contribute evidence toward the psychometric properties of the Arabic version of the PGI. Method A total of 75 participants with MS completed three QOL measures; PGI, the Patient Determined Disease Steps (PDDS), and EQ-5D. Generalized Estimating Equations (GEE) were used to compare the total score of three QOL measures. Bland-Altman plot and Spearman’s correlation coefficient were used to study the relationships and differences between the PGI and the other study measures (PDDS and EQ-5D). Results Only 66 (88%) of the participants were able to complete the PGI. Overall, 36 areas of QOL concern were nominated by the participants using the PGI with the top 3 areas were an emotional function (47%), involuntary movement reaction functions (45.5%) and walking (44%). The average global score of the PGI was lower (34±22) than the global score of the EQ-5D (69±23) and the PDDS (68±24).PGI had a moderate correlation with EQ-5D and PPDS. Conclusion The Arabic version of the PGI is a feasible and acceptable measure among Jordanian with MS and it captures a wide spectrum of important areas that contribute to QOL than EQ-5D and PDDS. PGI could improve the decision making and guide health-care professionals to provide appropriate intervention programs to reduce the burdens from MS disease and improve QOL.

scholarly journals Effectiveness of massage therapy on fatigue and pain in patients with multiple sclerosis: A systematic review and meta-analysis

2021 ◽  
Vol 7 (2) ◽  
pp. 205521732110227
Author(s):  
Shahin Salarvand ◽  
Mohammad Eghbal Heidari ◽  
Kazem Farahi ◽  
Erfan Teymuri ◽  
Mohammad Almasian ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Systematic Review ◽  
Massage Therapy ◽  
Pharmacological Therapy ◽  
Mean Difference ◽  
Cochrane Library ◽  
Clinical Value ◽  
Significant Trial

Background Fatigue and pain are prevalent symptoms of multiple sclerosis (MS) and frequent complaint in MS patients, which reduce their quality of life. This study aimed to assess the effect of massage therapy on pain and fatigue in MS Patients. Method The original and Persian databases were searched included PubMed, web of science, embase, ovid, scopus, and the Cochrane Library, SID, and Iranedex from inception to November 2020. Studies that reported the effect of massage on fatigue and pain were included. Two investigators extracted all relevant data, independently. For deriving analysis, mean difference (MD) and standardized mean difference (SMD) were used. Result Ten studies were eligible acoording criteria. The effect of massage on fatigue showed significant improvement (−1.62; 95% CL −2.40, −0.83; p < .00001), also results of the systematic review showed a significant reduction in pain severity. Conclusion Massage as a complementary and non-pharmacological therapy might have been associated with alleviating fatigue and pain in M.S. patients. Based on the current study, massage intervention for MS patients could have possible clinical value for palliating pain and fatigue and improving quality of life; however, this matter needs further and more significant trial studies.

Long-Term Effectiveness of Fingolimod for Multiple Sclerosis in a Real-World Clinical Setting

2021 ◽  
pp. 1-6
Author(s):  
Cihat Uzunköprü ◽  
Yesim Beckmann ◽  
Sabiha Türe
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Real Life ◽  
Life Assessment ◽  
Health Related Quality ◽  
Serious Adverse Events ◽  
Related Quality ◽  
Health Related

<b><i>Introduction:</i></b> The primary aim of the present study was to evaluate the long-term efficacy of fingolimod in patients with multiple sclerosis (MS); secondary aims were to describe the safety of fingolimod with the evaluation of treatment satisfaction and impact on the quality of life in real life. <b><i>Methods:</i></b> We collected clinical, demographical, neuroradiological, and treatment data, including pre- and posttreatment status health-related quality of life from 286 MS patients consecutively treated with fingolimod. Clinical assessment was based on the Expanded Disability Status Scale (EDSS), and quality of life assessment was performed with MS-related quality of life inventory (MSQOLI). The data were recorded at baseline and every 6 months for 2 years. <b><i>Results:</i></b> One hundred and fourteen males and 172 females were enrolled. The annualized relapse rate and EDSS showed a statistically significant reduction during the observation period (<i>p</i> &#x3c; 0.001). The patients also demonstrated substantial improvements in magnetic resonance imaging (MRI) outcomes (<i>p</i> &#x3c; 0.001). Health-related quality of life scores improved significantly between baseline and 24-month visit (<i>p</i> &#x3c; 0.001). No serious adverse events occurred. <b><i>Conclusion:</i></b> In our cohort, fingolimod treatment was associated with reduced relapse, MRI activity, and improved EDSS and MSQOLI scores. Additionally, fingolimod has been able to maintain its effectiveness over a considerable long period of treatment.

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