scholarly journals STUDY OF IRON OXIDE NANOPARTICLES DOPED WITH COPPER: ANTIMICROBAL AND PHOTOCATALYTICAL ACTIVITY

2020 ◽  
Vol 11 (2) ◽  
Author(s):  
Aleksandra Šmitran ◽  
Dijana Jelić ◽  
Sanja Pržulj ◽  
Savka Vračević ◽  
Dragana Gajić ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Iron Oxide ◽  
Antimicrobial Resistance ◽  
Acinetobacter Baumannii ◽  
Iron Oxide Nanoparticles ◽  
Copper Ions ◽  
Technological Development ◽  
Inhibition Zone ◽  
Diffusion Method ◽  
Oxide Nanoparticles

Last decade is designated as the postantibiotic era due to increasing number of resistant and multiresistant strains of microorganisms, which developed resistance to one or more antibiotics. Antimicrobial resistance becomes a global health problem. This phenomenon of antimicrobial resistance will undoubtedly affect the efficiency and use of antibiotics in the future. Science and technological development are committed to researching and developing new antibiotics that will satisfy the missing criteria and address the problem of antimicrobial resistance. One of the possible solutions lies in nanotechnologies. Nanoparticles have been isolated as one of the most promising substances on which microorganisms rarely or even develop mechanisms of resistance. The nanoparticles may be in conjunction with already existing antibiotics structures and contribute to the improvement of physicochemical properties in order to successfully overcome the mechanism of antimicrobial resistance. By designing nanoparticles with proper physicochemical and biochemical characteristics we determine their application. The aim of this research is to dope synthesized iron oxide nanoparticles with copper ions in order to test their antimicrobial activity and to evaluate their use as potential antimicrobial agent. Extracts of green tea and ascorbic acid were used as reduction agent for the iron oxide nanoparticles doped with Cu. The antimicrobial activity of the synthesized nanoparticles on the isolates Acinetobacter baumannii and methicillin resistant Staphylococcus aureus (MRSA) was performed by the agar well diffusion method. Synthesized iron oxide nanoparticles showed activity against Acinetobacter baumannii with inhibition zone around 12 mm. Photocatalytical activity was also evaluated by UV/VIS spectrophotometry. Samples doped with copper showed much better photocatalytical performances.

scholarly journals Structural Characterization, Antimicrobial and Antioxidant Assay of Biogenically Synthesized Maghemite (γ-Fe2O3) Nanoparticles

2021 ◽  
pp. 32-41
Author(s):  
A. Leema Rose ◽  
B. Shabushree ◽  
Preeja P. Thattil
Keyword(s):  
Antimicrobial Activity ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Leaf Extract ◽  
Ferrous Sulphate ◽  
Diffusion Method ◽  
Oxide Nanoparticles ◽  
Fe2o3 Nanoparticles ◽  
X Ray

Aims: The present study focused on the optical and morphological characterization, antioxidant and antimicrobial activities of the biogenically synthesized iron oxide nanoparticles.  Methods: The preliminary phytochemical screening was done for the leaf extract of Annona reticulate L. The leaf extract and Ferrous Sulphate heptahydrate were used to synthesize the iron oxide nanoparticles under room temperature. The determination of antioxidant activity was done using DPPH free radical scavenging assay and the determination of antimicrobial activity using disc diffusion method. Results: The UV-visible spectra showed the sharp absorption peak at 278 nm. The Fourier-transform infrared spectroscopy studies revealed the role of phytochemical constituents in the leaf extract for the iron oxide nanoparticles formation.  X-ray diffraction pattern showed the presence of γ phase of Fe2O3 nanoparticles. Scanning electron microscope analysis showed the moderately spherical morphology of γ-Fe2O3 nanoparticles and Energy-dispersive X-ray peaks showed the presence of iron and oxygen in the synthesized nanoparticles.  Particle size analysis showed that the synthesized γ-Fe2O3possessed an average size of 115.9 nm. Conclusion: The synthesized γ-Fe2O3 nanoparticles have potential antioxidant and antimicrobial activity.

Antimicrobial activity of citric acid functionalized iron oxide nanoparticles –Superparamagnetic effect

2020 ◽  
Vol 46 (8) ◽  
pp. 10942-10951 ◽  
Author(s):  
Sidra Khan ◽  
Zaheer H. Shah ◽  
Saira Riaz ◽  
Naveed Ahmad ◽  
Shumaila Islam ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Iron Oxide ◽  
Citric Acid ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles

scholarly journals Iron Oxide Nanoparticles for Biomedical Applications: A Perspective on Synthesis, Drugs, Antimicrobial Activity, and Toxicity

Antibiotics ◽  
2018 ◽  
Vol 7 (2) ◽  
pp. 46 ◽  
Author(s):  
Laís Arias ◽  
Juliano Pessan ◽  
Ana Vieira ◽  
Taynara Lima ◽  
Alberto Delbem ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Oxide Nanoparticles

scholarly journals Magnetic Properties and Biological Activity Evaluation of Iron Oxide Nanoparticles

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Alina Mihaela Prodan ◽  
Simona Liliana Iconaru ◽  
Carmen Mariana Chifiriuc ◽  
Coralia Bleotu ◽  
Carmen Steluta Ciobanu ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Room Temperature ◽  
Aqueous Suspension ◽  
Hysteresis Loops ◽  
Biological Properties ◽  
Oxide Nanoparticles ◽  
Metallic Ions ◽  
Tem Analysis

The aim of this study was to provide information about the biological properties of iron oxide nanoparticles (IO-NPs) obtained in an aqueous suspension. The IO-NPs were characterized by transmission electron microscopy (TEM). Analysis of hysteresis loops data at room temperature for magnetic IO-NPs sample indicated that the IO-NPs were superparamagnetic at room temperature. The calculated saturation magnetization for magnetic iron oxide wasMs= 18.1 emu/g. The antimicrobial activity of the obtained PMC-NPs was tested against Gram-negative (Pseudomonas aeruginosa1397,Escherichia coliATCC 25922), Gram-positive (Enterococcus faecalisATCC 29212,Bacillus subtilisIC 12488) bacterial as well as fungal (Candida krusei963) strains. The obtained results suggested that the antimicrobial activity of IO-NPs is dependent on the metallic ions concentrations and on the microbial growth state, either planktonic or adherent. The obtained IO-NPs exhibited no cytotoxic effect on HeLa cells at the active antimicrobial concentrations.

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