Overdose Prevention Through Medical Treatment of Opioid Use Disorders

2018 ◽  
Vol 169 (3) ◽  
pp. 190 ◽  
Author(s):  
Nora D. Volkow ◽  
Eric M. Wargo
2020 ◽  
Vol 35 (5) ◽  
pp. 1537-1544
Author(s):  
Utibe R. Essien ◽  
Florentina E. Sileanu ◽  
Xinhua Zhao ◽  
Jane M. Liebschutz ◽  
Carolyn T. Thorpe ◽  
...  

2017 ◽  
Vol 35 (2) ◽  
pp. 248-250
Author(s):  
Christine N. Runyan ◽  
Amber L. Hewitt ◽  
Stephen A. Martin ◽  
Daniel Mullin

2021 ◽  
pp. 113710
Author(s):  
Tao Wang ◽  
Xun Zhu ◽  
Hyun Yi ◽  
Jun Gu ◽  
Shue Liu ◽  
...  

Author(s):  
Mina M. Rizk ◽  
Sarah Herzog ◽  
Sanjana Dugad ◽  
Barbara Stanley

2020 ◽  
Vol 207 ◽  
pp. 107732 ◽  
Author(s):  
Gwen Lapham ◽  
Denise M. Boudreau ◽  
Eric A. Johnson ◽  
Jennifer F. Bobb ◽  
Abigail G. Matthews ◽  
...  

Author(s):  
Heather M Santa ◽  
Samira G Amirova ◽  
Daniel J Ventricelli ◽  
George E Downs ◽  
Alexandra A Nowalk ◽  
...  

Abstract Purpose Opioid misuse and overdose deaths remain a public health concern in the United States. Pennsylvania has one of the highest rates of opioid overdose deaths in the country, with Philadelphia County’s being 3 times higher than the national average. Despite several multimodal interventions, including use of SBIRT (screening, brief intervention, and referral to treatment) methods and naloxone distribution, the rate of overdose deaths remains high. Methods To gain insights on strategies for improving access to naloxone and naloxone distribution by pharmacists in Philadelphia County, a study was conducted in 11 community pharmacies (chain and independent) in Philadelphia. Twenty-four pharmacists were recruited and completed SBIRT and naloxone trainings. Each pharmacy elected to have at least 1 pharmacy champion who received additional training on and helped develop pharmacy site–specific naloxone dispensing protocols. Results Pre-post survey results showed a reduction in stigmatizing attitudes regarding naloxone dispensing and an increase in pharmacists’ understanding of the standing order and appropriate naloxone use. There was an increase in pharmacists’ self-reported confidence in their ability to appropriately identify, discuss, and dispense naloxone to patients. All pharmacies increased their average monthly dispensing rate following protocol implementation. Conclusion Pharmacists who received both trainings were more likely to change naloxone dispensing practices, leading to an overall increase in naloxone dispensing by community pharmacists. The study addressed overall gaps in pharmacists’ knowledge, reduced stigma, and prepared pharmacists to address opioid use and overdose prevention with their patients. The described pharmacist-led patient counseling and intervention service for overdose prevention may be explored as a model for other community pharmacies to adopt to improve naloxone dispensing and similar interventions to reduce overdose deaths.


F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 87 ◽  
Author(s):  
George E. Woody

The development of medications for treating persons with opioid use disorders has expanded the number of evidence-based treatment options, particularly for persons with the most severe disorders. It has also improved outcomes compared to psychosocial treatment alone and expanded treatment availability by increasing the number of physicians involved in treatment and the settings where patients can be treated. The medications include methadone, buprenorphine, buprenorphine/naloxone, and extended-release injectable naltrexone. Studies have shown that they are most effective when used over an extended, but as-yet-unspecified, period of time and with counseling and other services, particularly for the many with psychosocial problems. Though controversial in some cultures, well-designed studies in Switzerland, the Netherlands, Germany, and Canada have demonstrated the efficacy of supervised heroin injecting for persons who responded poorly to other treatments, and this treatment option has been approved by Switzerland and a few other E.U. countries. The degree to which medication-assisted therapies are available is dependent on many variables, including national and local regulations, preferences of individual providers and their geographical location, treatment costs, and insurance policies. Greater availability of medication-assisted therapies has become a major focus in the U.S. and Canada, where there has been a marked increase in deaths associated with heroin and prescription opioid use. This paper provides a brief summary of these developments.


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