scholarly journals Chronic Liver Disease Lowering Physical and Mental Health Dimensions

2021 ◽  
Vol 24 (3) ◽  
pp. 149-156
Author(s):  
Apriliani Siburian ◽  
Ching Fen Chang

The most prevalent diseases within the world related to major illness and mortality are chronic liver diseases. The developing pervasiveness of chronic liver disease has resulted in increased interest in health-related quality of life, which incorporates the physical well-being of a patient and his emotional and social well-being. This study aimed to define the quality of life of patients with chronic liver disease. This study used the Quality-of-Life Short Form 36 Indonesian version to examine 102 patients with chronic liver disease from two hospitals with a descriptive design. The quality of life of the patients was comparatively low (M ± SD: physical, 42.4 ± 18.33; mental, 48.44 ± 17.19). On both the physical and mental health dimensions of quality of life, the patients in this study scored less than 50 on a scale of 0 to 100, with low scores indicating the low quality of life both physically and mentally. Improving quality of life necessitates a multidisciplinary strategy that combines physical and mental health screening and management. Surrounding support will encourage adaptive coping mechanisms to manage the illness for improving quality of life. AbstrakPenyakit Hati Kronis Menurunkan Dimensi Kesehatan Fisik dan Mental. Penyakit yang paling umum di dunia yang berhubungan dengan penyakit utama dan kematian adalah penyakit hati kronis. Penyebaran penyakit hati kronis yang berkembang telah menghasilkan peningkatan minat pada kualitas hidup yang berhubungan dengan kesehatan, yang mencakup kesejahteraan fisik pasien dan kesejahteraan emosional dan sosialnya. Tujuan dari penelitian ini adalah untuk menjabarkan kualitas hidup pasien penyakit hati kronis. Penelitian ini menggunakan Quality-of-Life Short Form 36 versi Bahasa Indonesia untuk mengumpulkan data dari 102 pasien dari dua rumah sakit melalui desain deskriptif. Penelitian ini menunjukkan bahwa kualitas hidup pasien relatif rendah (M ± SD: fisik, 42,4 ± 18,33; mental, 48,44 ± 17,19). Pada kedua dimensi kualitas hidup yaitu kesehatan fisik dan mental, pasien dalam penelitian ini mendapat nilai kurang dari 50 pada skala 0 hingga 100, dengan nilai rendah menunjukkan kualitas hidup rendah baik fisik maupun mental. Peningkatkan kualitas hidup pasien memerlukan strategi multidisiplin yang menggabungkan skrining dan manajemen kesehatan fisik dan mental. Dukungan lingkungan akan mendorong mekanisme koping yang adaptif untuk mengelola penyakit dalam meningkatkan kualitas hidup.Kata Kunci: Indonesia, kualitas hidup, penyakit hati kronis, sirosis

2018 ◽  
Vol 75 (5) ◽  
pp. 453-460
Author(s):  
Dusan Popovic ◽  
Darija Kisic-Tepavcevic ◽  
Nada Kovacevic ◽  
Tamara Milovanovic ◽  
Miodrag Krstic ◽  
...  

Background/Aim. Quality of life is impaired in patients with the chronic liver disease (CLD). Patients with this disease have numerous disabling problems which lead to a reduced health related quality of life (HRQoL). The aim of our study was to evaluate the predictive value of selected socio-demographic and clinical characteristics on HRQoL in Serbian cohort of patients with the CLD. Methods. Over a period of one year, we performed a study which included patients with the CLD. We used Short Form Health Survay-36 (SF-36) for assessment of HRQoL. The assessment of depression and anxiety was made by using Hamilton scale of depression and anxiety, while the assessment of fatigue was performed by Fatigue severity scale. Results. The study included 103 patients with the CLD. The average values of the overall SF-36 scores were 52.6 ? 20.4, while the mean score of the composite scores were 53.5 ? 19.6 for the Mental component summary and 49.8 ? 21.3 for the Physical component summary. Some domains of HRQoL were significantly affected by following factors: gender, age, employment status, alcohol consumption, depression, anxiety and fatigue. Predictors of physical components of HRQoL were employment, depression and fatigue, and predictors of mental components were depression and fatigue. Conclusion. The tested socio-demographic, clinical and behavioral factors have an impact on the HRQoL in patients with the CLD. The most important predictors of HRQoL are behavioral factors suggesting the need for an adequate therapeutic action in order to improve the HRQoL in these patients.


2021 ◽  
Vol 11 (12) ◽  
pp. 1387
Author(s):  
Oana-Mihaela Plotogea ◽  
Gina Gheorghe ◽  
Madalina Stan-Ilie ◽  
Gabriel Constantinescu ◽  
Nicolae Bacalbasa ◽  
...  

The present study aims to assess the sleep characteristics and health-related quality of life (HRQOL) among patients with chronic liver diseases (CLDs), as well as the relationship between them. We conducted a prospective cross-sectional study, over a period of eight months, on patients with CLDs. Sleep was assessed by subjective tools (self-reported validated questionnaires), semi-objective methods (actigraphy), and HRQOL by using the 36-Item Short Form Survey (SF-36) and Chronic Liver Disease Questionnaire (CLDQ). The results indicated that 48.21% of patients with CLDs had a mean Pittsburgh Sleep Quality Index (PSQI) score higher than five, suggestive of poor sleep; 39.29% of patients had a mean Epworth Sleepiness Scale (ESS) score ≥11, indicative of daytime sleepiness. Actigraphy monitoring showed that patients with cirrhosis had significantly more delayed bedtime hours and get-up hours, more awakenings, and more reduced sleep efficacy when compared to pre-cirrhotics. The CLDQ and SF-36 questionnaire scores were significantly lower in cirrhotics compared to pre-cirrhotics within each domain. Moreover, we identified significant correlations between the variables from each questionnaire, referring to HRQOL and sleep parameters. In conclusion, sleep disturbances are commonly encountered among patients with CLDs and are associated with impaired HRQOL. This is the first study in Romania that assesses sleep by actigraphy in a cohort of patients with different stages of CLD.


2001 ◽  
Vol 96 (7) ◽  
pp. 2199-2205 ◽  
Author(s):  
Zobair M Younossi ◽  
Navdeep Boparai ◽  
Lori Lyn Price ◽  
Michelle L Kiwi ◽  
Marilyn McCormick ◽  
...  

2014 ◽  
Vol 17 (2) ◽  
pp. 222-229 ◽  
Author(s):  
Victoria Menzies ◽  
Nancy Jallo ◽  
Patricia Kinser ◽  
Jo Lynne W. Robins ◽  
Kyungeh An ◽  
...  

Liver disease affects over 25 million people in the United States and, despite advances in medical management resulting in increased survival, a majority of these individuals report multiple co-occurring symptoms that severely impair functioning and quality of life. The purpose of this review is to (1) propose defining these co-occurring symptoms as a symptom cluster of chronic liver disease (CLD), (2) discuss putative underlying biological mechanisms related to CLD, including the liver–gut–brain axis and influence of the microbiome, and (3) discuss the implications for biobehavioral research in this patient population. Biobehavioral research focusing on the interrelated, and possibly synergistic, mechanisms of these symptoms may lead to the development and testing of targeted symptom management interventions for improving function and quality of life in this growing patient population.


2015 ◽  
Vol 5 ◽  
pp. S44
Author(s):  
Pavan Hanchanale ◽  
K. Janani ◽  
Joy Varghese ◽  
S. Vijaya ◽  
V. Jayanthi ◽  
...  

2019 ◽  
Vol 15 (2) ◽  
pp. 80-87
Author(s):  
Ishrat J. Khan

Background:There has been an increasing interest in the past several decades to study the relationship between spirituality and religion with physical and mental health as well as the various quality of life measures. This trend has led to the creation of an area of study called epidemiology of religion and spirituality. The policy shifts at various levels, in the mental health field, has occurred as well to educate healthcare providers, and address patients’ spiritual /religious needs in clinical settings. Despite these advances in research and policy shift, there is still some resistance in the health care community to assess and address the spiritual needs of patients in clinical settings.Objective:The objective is to review the published articles on spirituality/religion and its relationship with mental and physical wellbeing and discuss limitations of such research. The review articles on assessment and interventions to address spiritual or religious needs in clinical settings were also included.Methods:Author conducted a literature search using books@Ovid, Journals@Ovid Full Text, Your Journals@Ovid, Ovid MEDLINE® 1946 to January week 4 2019, Ovid Medline® and Epub Ahead of Print, In-Process & Other Non-Indexed Citations and Daily without Revisions 2015-January 28, 2019; Ovid MD and Psychiatry Online.Results:A total of 1,040 articles were identified using keywords spirituality, religion, mental health, physical health, psychological well-being, healthy beliefs, psychopathological beliefs and quality of life. The search result included original research papers, review articles and commentaries.Conclusion:The review articles were narrowed to 100 articles based on relevance to the objectives outlined above. Seventy-five articles were referenced at the end.


2018 ◽  
Vol 28 (1) ◽  
pp. 48-54
Author(s):  
Hiang Keat Tan ◽  
Yean Lee ◽  
Pei Yuh Chia ◽  
Shaik Hussain Nurshifa ◽  
Travis Kim Chye Tan ◽  
...  

Background: Patients with chronic liver disease often suffer from poor quality of life. The Chronic Liver Disease Questionnaire (CLDQ) is a validated tool to assess health-related quality of life in these patients. It has been translated and validated for use in many countries and languages globally. Objectives: We aimed to translate Mainland Chinese Mandarin to Singapore Mandarin and perform cross-cultural adaption of CLDQ for the Mandarin-speaking population in Singapore (CLDQ-SG). Methods: This study was conducted based on the International Society for Pharmacoeconomics and Outcomes Research Principles of Good Practice. The study consisted of two parts: part one involved cognitive debriefing and cultural adaption of CLDQ, and part two was a pilot study on the first version of CLDQ-SG among adult patients with chronic liver disease in a tertiary hospital. Results: During the cognitive debriefing process of part one, questions beginning with “recent” (最近) two weeks in Mandarin were changed to “last” (在过去) two weeks. Eighteen patients were recruited for part two of the study (50% male, mean age 49±13 years). Time taken to complete CLDQ-SG was 15±8 minutes, and the mean score was 5.1±0.5. The reliability of measurements for all domains was good, with an intra-class correlation coefficient ≥0.8. Items one and four needed further restructuring. There were no discrepancies between CLDQ and CLDQ-SG. Conclusion: This study showed that CLDQ-SG was culturally acceptable by the Mandarin-speaking population in Singapore. There were only two items that needed revision in the finalized CLDQ-SG.


Medicina ◽  
2020 ◽  
Vol 56 (12) ◽  
pp. 647
Author(s):  
Natasa Todorovic ◽  
Milutin Vracevic ◽  
Nina Rajovic ◽  
Vedrana Pavlovic ◽  
Petar Madzarevic ◽  
...  

Background and objectives: The COVID-19 pandemic has had an unprecedented reliance on informal caregivers as one of the pillars of healthcare systems. The aim of this study was to assess the quality of life of informal caregivers during the COVID-19 epidemic in Serbia. Materials and Methods: A cross-sectional study was conducted among informal caregivers during the COVID-19 epidemic in Serbia. Physical and mental quality of life was measured by the 36-Item Short-Form Health Survey. Additional data included sociodemographic characteristics, caregiver and care recipient characteristics, and COVID-19 related concerns. The qualitative component was performed using focus groups and individual in-depth interviews. Results: Out of 112 informal caregivers enrolled, most were female (80%), and the average age was 51.1 ± 12.3 years. The majority was delivering care to one person, who was a family member, on a daily basis (86.4%, 92%, and 91.1%, respectively). In multiple regression models, significant predictors of caregivers’ physical health were delivering care to a family member and a higher level of care complexity, while significant predictors of caregivers’ mental health were a higher level of care complexity and increased concerns about self-health and the health of the person being cared for due to the COVID-19 epidemic. Conclusions: Informal caregivers are experiencing negative physical and mental health outcomes during the COVID-19 epidemic in Serbia.


2010 ◽  
Vol 40 (6) ◽  
pp. 581-590 ◽  
Author(s):  
Namita Panagaria ◽  
Kanika Varma ◽  
Sandeep Nijhawan ◽  
R.R. Rai

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