scholarly journals Periodontal microbiota and microorganisms isolated from heart valves in patients undergoing valve replacement surgery in a clinic in Cali, Colombia

Biomédica ◽  
2017 ◽  
Vol 37 (4) ◽  
pp. 516 ◽  
Author(s):  
Sandra Moreno ◽  
Beatriz Parra ◽  
Javier E. Botero ◽  
Freddy Moreno ◽  
Daniel Vásquez ◽  
...  
Keyword(s):  
Valve Replacement ◽  
Porphyromonas Gingivalis ◽  
Heart Valves ◽  
Propionibacterium Acnes ◽  
Clostridium Beijerinckii ◽  
Prevotella Intermedia ◽  
Eikenella Corrodens ◽  
Replacement Surgery ◽  
Clostridium Bifermentans ◽  
Valve Replacement Surgery

Introducción. La periodontitis es una enfermedad infecciosa que afecta los tejidos de soporte del diente y se asocia con diferentes enfermedades sistémicas, incluida la enfermedad cardiovascular. Los estudios microbiológicos permiten detectar microorganismos a partir de muestras subgingivales y cardiovasculares.Objetivo. Describir la microbiota periodontal cultivable y la presencia de microorganismos en válvulas cardiacas de pacientes sometidos a cirugía de reemplazo valvular en una clínica de Cali.Materiales y métodos. Se analizaron 30 muestras subgingivales y de tejidos valvulares mediante cultivo en medio bifásico, agar de sangre con suplemento y agar tripticasa de soya con antibiótico. Las muestras de las válvulas se analizaron mediante reacción en cadena de la polimerasa (PCR) convencional.Resultados. Los patógenos periodontales aislados de bolsas periodontales fueron Fusobacterium (50 %), Prevotella intermedia/nigrescens (40 %), Campilobacter rectus (40 %), Eikenella corrodens (36,7 %), bacilos entéricos Gram negativos (36,7 %), Porphyromonas gingivalis (33,3 %) y Eubacterium (33,3 %). Los agentes patógenos aislados de la válvula aórtica fueron Propionibacterium acnes (12 %), bacilos entéricos Gram negativos (8 %), Bacteroides merdae (4 %) y Clostridium bifermentans (4 %), y de la válvula mitral, P. acnes y Clostridium beijerinckii. La PCR convencional no arrojó resultados positivos para agentes patógenos orales y solo se detectó ADN bacteriano en dos muestras.Conclusiones. La microbiota periodontal de pacientes sometidos a cirugía de reemplazo valvular estaba conformada por especies Gram negativas que han sido relacionadas con infecciones en tejidos extraorales; sin embargo, no se encontraron agentes patógenos periodontales en los tejidos de las válvulas. Aunque hubo muestras de estos tejidos y subgingivales, positivas para bacilos entéricos Gram negativos, no es posible asegurar que tuvieran el mismo origen filogenético.

Micromechanical Analysis of Mouse Aortic Valve Leaflets With Atomic Force Microscopy

2012 ◽  
Author(s):  
M. K. Sewell-Loftin ◽  
Christopher B. Brown ◽  
H. Scott Baldwin ◽  
W. David Merryman
Keyword(s):  
Valve Replacement ◽  
Heart Valve ◽  
Congenital Heart ◽  
Heart Valves ◽  
Heart Defects ◽  
Biomechanical Properties ◽  
The United States ◽  
Heart Valve Disease ◽  
Replacement Surgery ◽  
Valve Replacement Surgery

A significant limitation in our ability to study congenital heart valve disease and defects is due to lack of appropriate animal models and also in part to our incomplete understanding of biomechanical properties of the leaflet tissues. Biomechanical changes in leaflets as they develop and throughout a person’s lifetime are not well understood. With improved understanding of such changes, more intuitive approaches could be used to develop tissue engineered heart valves. Each year in the United States, over 20,000 children are born with congenital heart defects; many requiring valve replacement surgery [1–2]. Additionally, over 300,000 people worldwide require heart valve replacement surgery each year [3–4]. The creation of better valve replacements would improve treatment and quality of patient life.

Myocardial Potassium and Lactate Balance during Valve-Replacement Surgery

Circulation ◽  
1969 ◽  
Vol 39 (5s1) ◽  
Author(s):  
COLIN W. MCCORD ◽  
RICHARD S. CRAMPTON ◽  
MICHEL G. NASSER ◽  
ROBERT B. CASE ◽  
Anna Maria Wachter
Keyword(s):  
Valve Replacement ◽  
Replacement Surgery ◽  
Valve Replacement Surgery

Outcomes after Mitral and Aortic Valve Replacement Surgery: Comparison and Predictors

2011 ◽  
Vol 20 (1) ◽  
pp. 53
Author(s):  
Mahmoon Shirzad ◽  
Abbasali Karimi ◽  
Seyed Hossein Ahmadi ◽  
Samaneh Dowlatshahi ◽  
Saeed Davoodi ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Replacement Surgery ◽  
Valve Replacement Surgery

RELATIONSHIP OF PREOPERATIVE RIGHT VENTRICULAR FUNCTION AND OUTCOME AFTER MITRAL VALVE REPLACEMENT SURGERY – A PROSPECTIVE OBSERVATIONAL STUDY

2020 ◽  
pp. 43-46
Author(s):  
Debashis Karmokar ◽  
Pinaki Majumdar ◽  
Manjushree Ray ◽  
Asim Kumar Kundu
Keyword(s):  
Mitral Valve ◽  
Right Ventricular ◽  
Ventricular Function ◽  
Valve Replacement ◽  
Mitral Valve Replacement ◽  
Right Ventricular Function ◽  
Low Cardiac Output Syndrome ◽  
Replacement Surgery ◽  
Grade 3 ◽  
Valve Replacement Surgery

Objective:Right ventricular dysfunction constitutes a major risk factor for patients suffering from degenerative mitral valve disease. The objective of this study was to assess right ventricular function by echocardiography and to detect role of right ventricular functions in prediction of outcome following mitral valve replacement operation in patients with rheumatic heart disease involving mitral valve. Methods:Transthoracic 3D echocardiography was done in 52 patients posted for mitral valve replacement surgery. Right ventricular function was analyzed by measuring fractional area change (FAC) of right ventricle, tethering distance and, tricuspid annular plane systolic excursion (TAPSE). Tricuspid regurgitation was graded 0 to 4. Based on echocardiographic ndings of right ventricle, patients were allocated in two groups; Group A (normal right ventricular function) and Group B (poor right ventricular function). After surgery, incidence of complications such as; low cardiac output syndrome, refractory arrhythmia and, sepsis were compared in two group. Results: Incidence of postoperative complication such as low cardiac output syndrome and sepsis was signicantly more in patients with poor right ventricular function. Right ventricular variables, FAC <35%, TAPSE <17 mm and tethering distance > 8 mm are independent predictors of postoperative complications. Tricuspid valve was repaired in patients with grade 3 and 4 regurgitation. Therefore cardiopulmonary bypass time was signicantly more in patients with grade 3 and 4 TR (84.42±69.77 min) (p<0.01). Duration of intensive care support was also signicantly more in patients with poor right ventricular function (p<0.001) Conclusion: To predict possible complications and outcome following mitral valve replacement surgery, right ventricular functions should be thoroughly assessed by 3D echocardiography

Postconditioning the Human Heart with Adenosine in Heart Valve Replacement Surgery

2007 ◽  
Vol 83 (6) ◽  
pp. 2066-2072 ◽  
Author(s):  
Zhen-Xiao Jin ◽  
Jing-Jun Zhou ◽  
Mei Xin ◽  
Dao-Rong Peng ◽  
Xi-Ming Wang ◽  
...  
Keyword(s):  
Valve Replacement ◽  
Heart Valve ◽  
Human Heart ◽  
Heart Valve Replacement ◽  
Replacement Surgery ◽  
Valve Replacement Surgery
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