scholarly journals Indirect Doppler flow systolic blood pressure measurements taken with and without headphones in privately-owned, conscious dogs

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e7440
Author(s):  
India R. Gill ◽  
Joshua M. Price ◽  
Jacqueline C. Whittemore
Keyword(s):  
Blood Pressure ◽  
Rank Correlation ◽  
Correlation Coefficients ◽  
Anxiety Score ◽  
White Coat Hypertension ◽  
Doppler Flow ◽  
Arterial Blood ◽  
Systolic Arterial Blood Pressure ◽  
Accuracy Of Results ◽  
Privately Owned

Objective The purpose of this study was to assess the effect of headphone use and covariates on indirect radial Doppler flow systolic arterial blood pressure (BP) measurements in dogs. Methods Between May and August 2018, 100 privately-owned dogs were enrolled. Blood pressure was measured in lateral recumbency, with and without headphones, using a randomized crossover design. The initial BP, mean of BP 2-6, weight, BCS, MCS, anxiety score, and heart rate were recorded. Mixed effects crossover analyses and Spearman rank correlation coefficients were determined. Results Eighty-four dogs completed the study. Eleven dogs were removed due to excessive anxiety, 10 of which were in the non-headphone first group. The number of dogs diagnosed as hypertensive did not differ between measurement types (19 vs. 18), with seven dogs categorized as hypertensive during both periods. Significant differences in BP were identified (F[1, 80] = 4.3, P = 0.04) due to higher results for measurements taken without headphones for BP 1, but not BP 2-6. Systolic BP was positively correlated with anxiety score, age, and weight. Conclusions and Clinical Relevance Though BP 1 was significantly higher when taken without headphones, this pattern did not persist for BP 2-6. Lack of association between BP 2-6 results and measurement type could reflect exclusion of dogs most sensitive to white coat hypertension, acclimation to technique, or improved sound quality of headphones. Given significantly higher BP 1 results and disproportionate exclusion of dogs due to anxiety when measurements first were taken without headphones, use of headphones is recommended to improve accuracy of results.

scholarly journals Effects of various factors on Doppler flow ultrasonic radial and coccygeal artery systolic blood pressure measurements in privately-owned, conscious dogs

PeerJ ◽  
2017 ◽  
Vol 5 ◽  
pp. e3101 ◽  
Author(s):  
Allison P. Mooney ◽  
Dianne I. Mawby ◽  
Joshua M. Price ◽  
Jacqueline C. Whittemore
Keyword(s):  
Blood Pressure ◽  
Body Condition Score ◽  
Correlation Coefficients ◽  
Analysis Of Covariance ◽  
Measurement Site ◽  
Arterial Blood ◽  
Condition Score ◽  
Systolic Arterial Blood Pressure ◽  
Patient Variables ◽  
Privately Owned

ObjectiveThe purpose of this study was to assess the effects of age, body condition score (BCS) and muscle condition score (MCS) on indirect radial and coccygeal Doppler systolic arterial blood pressure (SAP) measurements in dogs.MethodsSixty-two privately-owned dogs were enrolled between June and July 2016. The BCS and MCS were determined by two investigators. Blood pressure was measured per published guidelines and using headphones, and the order of measurement site was randomized. Dogs were positioned in right lateral recumbency for radial measurements and sternal recumbency or standing for coccygeal measurements. Associations between SAP and other variables were assessed by correlation coefficients and analysis of covariance.ResultsRadial and coccygeal SAP measurements were moderately correlated (r = 0.45,P < 0.01). Radial SAP measurements were higher than coccygeal SAP measurements (mean difference 9 mmHg,P < 0.01), but discordance occurred in both directions. No difference was observed between the first measurement taken, the average of measurements 2–6, or the average of all 6 measurements for either the radial (128, 129, and 129 mmHg;P = 0.36) or coccygeal (121, 122, and 122 mmHg;P = 0.82) site. Associations were not found between SAP measurements for either site and age, weight, BCS, MCS, anxiety score, or cuff size. Heart rate decreased significantly from the start of acclimation to the end of the first data collection series regardless of site (P < 0.01).Conclusions and Clinical RelevanceInitial measurement site can be based on patient and operator preference given lack of associations with patient variables, but the same site should be used for serial SAP measurements given discordant results between sites.

Terlipressin Versus  Norepinephrine to Correct Refractory Arterial Hypotension after General Anesthesia in Patients Chronically Treated with Renin-Angiotensin System Inhibitors

2003 ◽  
Vol 98 (6) ◽  
pp. 1338-1344 ◽  
Author(s):  
Gilles Boccara ◽  
Alexandre Ouattara ◽  
Gilles Godet ◽  
Eric Dufresne ◽  
Michèle Bertrand ◽  
...  
Keyword(s):  
Blood Pressure ◽  
General Anesthesia ◽  
Arterial Blood Pressure ◽  
Renin Angiotensin System ◽  
Arterial Hypotension ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
Arterial Blood ◽  
Long Term Treatment ◽  
Systolic Arterial Blood Pressure

Background Terlipressin, a precursor that is metabolized to lysine-vasopressin, has been proposed as a drug for treatment of intraoperative arterial hypotension refractory to ephedrine in patients who have received long-term treatment with renin-angiotensin system inhibitors. The authors compared the effectiveness of terlipressin and norepinephrine to correct hypotension in these patients. Methods Among 42 patients scheduled for elective carotid endarterectomy, 20 had arterial hypotension following general anesthesia that was refractory to ephedrine. These patients were the basis of the study. After randomization, they received either 1 mg intravenous terlipressin (n = 10) or norepinephrine infusion (n = 10). Beat-by-beat recordings of systolic arterial blood pressure and heart rate were stored on a computer. The intraoperative maximum and minimum values of blood pressure and heart rate, and the time spent with systolic arterial blood pressure below 90 mmHg and above 160 mmHg, were used as indices of hemodynamic stability. Data are expressed as median (95% confidence interval). Results Terlipressin and norepinephrine corrected arterial hypotension in all cases. However, time spent with systolic arterial blood pressure below 90 mmHg was less in the terlipressin group (0 s [0-120 s] vs. 510 s [120-1011 s]; P &lt; 0.001). Nonresponse to treatment (defined as three boluses of terlipressin or three changes in norepinephrine infusion) occurred in zero and eight cases (P &lt; 0.05), respectively. Conclusions In patients who received long-term treatment with renin-angiotensin system inhibitors, intraoperative refractory arterial hypotension was corrected with both terlipressin and norepinephrine. However, terlipressin was more rapidly effective for maintaining normal systolic arterial blood pressure during general anesthesia.

Detection of Seizure Activity in the Paralyzed Neonate Using Continuous Monitoring

PEDIATRICS ◽  
1982 ◽  
Vol 69 (5) ◽  
pp. 583-586
Author(s):  
Ronald N. Goldberg ◽  
Steven L. Goldman ◽  
R. Eugene Ramsay ◽  
Rosalyn Feller
Keyword(s):  
Blood Pressure ◽  
Oxygen Saturation ◽  
Arterial Blood Pressure ◽  
Cardiac Arrhythmias ◽  
Seizure Activity ◽  
Vital Signs ◽  
Transcutaneous Oxygen ◽  
Mechanically Ventilated ◽  
Arterial Blood ◽  
Systolic Arterial Blood Pressure

In experimental animals neurologic damage may occur during seizure activity whether the seizure is accompanied by motor activity and hypoxemia or whether the animal is paralyzed and normoxemic. These findings suggest that it may be important to detect seizure activity in the paralyzed neonate. Nine infants who were mechanically ventilated and paralyzed with pancuronium had their condition diagnosed as seizure activity. Vital signs were continuously monitored and six infants had either oxygen saturation or transcutaneous oxygen measured during seizure activity. For the group as a whole, rhythmic fluctuations in vital signs, cardiac rhythm, and oxygenation occurred every four minutes (range one to seven minutes) and lasted two minutes (range one to four minutes). In seven patients whose seizures were not accompanied by cardiac arrhythmias the following mean increases were noted: systolic arterial blood pressure, 15 mm Hg (range 7 to 36 mm Hg); heart rate, ten beats per minute (-11 to 30/min); oxygen saturation, 12% (range 4% to 20%); and transcutaneous oxygen, 31 mm Hg (range 14 to 45 mm Hg). Seizures in the two patients with cardiac arrhythmias were accompanied by a decrease in systolic arterial blood pressure of 27 mm Hg (range 15 to 40 mm Hg) and in oxygen saturation of 24% (range 20% to 28%). The presence of rhythmic fluctuation in vital signs and oxygenation should alert the physician to the possibility of seizure activity in the paralyzed neonate.

scholarly journals Association of Oral Status and Early Primary Hypertension Biomarkers among Children and Adolescents

2020 ◽  
Vol 17 (21) ◽  
pp. 7981
Author(s):  
Elzbieta Paszynska ◽  
Monika Dmitrzak-Weglarz ◽  
Danuta Ostalska-Nowicka ◽  
Michal Nowicki ◽  
Maria Gawriolek ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Children And Adolescents ◽  
Cystatin C ◽  
Rank Correlation ◽  
Permanent Teeth ◽  
Control Group ◽  
Oral Diseases ◽  
Arterial Blood ◽  
Early Primary ◽  
Bacterial Plaque

The aim of this case–control study was the evaluation of the association between biomarkers of early primary arterial hypertension (HA) and oral diseases among children and adolescents. Material and methods. Subjects suspected of primary HA (n = 180) underwent a complex evaluation of their vascular status: blood pressure, heart rate, vascular stiffness, sympathetic activity in a 24 h ambulatory examination, followed by measurement of serum uric acid (UA), cystatin C, and creatinine. This procedure allowed the identification of children with primary (n = 58) and secondary HA (n = 74), as well as of children with normal arterial blood pressure, who served as a control group (n = 48). All subjects with secondary HA were excluded from further investigation. Oral examination included the measurement of caries intensity (using the decayed, missing, filled index for permanent teeth DMFT /primary teeth dmft), bacterial plaque (by the plaque control record index, PCR%), and gingivitis (by the bleeding on probing index, BOP%). For statistical analysis, a linear regression model and Spearman rank correlation were used. Results. UA, cystatin C, and creatinine were not altered in the HA group. However, the number of decayed permanent teeth (DT) and the DMFT, PCR%, and BOP% indexes were significantly higher in the primary HA group compared to the control group (p = 0.0006; p = 0.02; p = 0.0009; p = 0.003). Our results are not sufficient to prove the important role of caries and gingival inflammation in the modulation of HA symptoms, although they prove the association of oral diseases with primary HA symptoms. This may indicate future strategies for preventive measures for hypertensive children and adolescents.

Comparison of simultaneous measurement of mouse systolic arterial blood pressure by radiotelemetry and tail-cuff methods

2004 ◽  
Vol 286 (6) ◽  
pp. H2408-H2415 ◽  
Author(s):  
Steven E. Whitesall ◽  
Janet B. Hoff ◽  
Alan P. Vollmer ◽  
Louis G. D'Alecy
Keyword(s):  
Blood Pressure ◽  
Linear Regression ◽  
Arterial Blood Pressure ◽  
Systolic Pressure ◽  
Pressure Measurements ◽  
Mouse Blood ◽  
Initial Flow ◽  
Arterial Blood ◽  
Systolic Arterial Blood Pressure ◽  
Tail Cuff

Radiotelemetry of mouse blood pressure accurately monitors systolic pressure, diastolic pressure, heart rate, and locomotor activity but requires surgical implantation. Noninvasive measurements of indirect systolic blood pressure have long been available for larger rodents and now are being reported more frequently for mice. This study compared mouse systolic arterial blood pressure measurements using implanted radiotelemetry pressure transducer with simultaneous tail-cuff measurements in the same unanesthetized mice. The pressure range for comparison was extended by inducing experimental hypertension or by observations of circadian elevations between 3 AM and 6 AM. Both trained and untrained tail-cuff operators used both instruments. Every effort was made to follow recommended manufacturer's instructions. With the initial flow-based tail-cuff instrument, we made 671 comparisons (89 sessions) and found the slope of the linear regression to be 0.118, suggesting poor agreement. In an independent assessment, 277 comparisons (35 sessions) of radiotelemetry measurements with the pulse based tail-cuff instrument were made. The slope of the linear regression of the simultaneous measurements of systolic pressures was 0.98, suggesting agreement. Bland-Altman analysis also supported our interpretation of the linear regression. Thus although reliable systolic pressure measurements are possible with either tail-cuff or radiotelemetry techniques, in our hands some tail-cuff instruments fail to accurately detect elevated blood pressures. These data, however, do not distinguish whether this instrument-specific tail-cuff failure was due to operator or instrument inadequacies. We strongly advise investigators to obtain an independent and simultaneous validation of tail-cuff determinations of mouse blood pressure before making critical genotyping determinations.

Abstract 237: Using the Thoracic Impedance to Predict Measures From Invasive Arterial Blood Pressure in Out-Of-Hospital Cardiac Arrest

Circulation ◽  
2019 ◽  
Vol 140 (Suppl_2) ◽  
Author(s):  
Andoni Elola ◽  
Elisabete Aramendi ◽  
Unai Irusta ◽  
Per-Olav Berve ◽  
Fredrik K Arnwald ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiac Arrest ◽  
Pearson Correlation ◽  
Correlation Coefficients ◽  
Invasive Blood Pressure ◽  
Pulse Detection ◽  
Non Invasive ◽  
Arterial Blood ◽  
Test Sets ◽  
Hospital Cardiac Arrest

Background: During cardiopulmonary resuscitation (CPR), pulse detection can be challenging. Invasive blood pressure measurements (IBP) can help monitoring patient hemodynamics, but arterial catheter placement is difficult. Transthoracic impedance (TI) measured between the defibrillator pads can detect circulation activity. We hypothesized that TI changes can predict the corresponding IBP, and potentially be used to non-invasively detect pulse during CPR. Materials and methods: We included 28 out of hospital cardiac arrest patients receiving CPR by the Oslo Emergency Service who had concurrent recordings of IBP (radial artery, BD, 20G, US) and TI (via defibrillator pads, LP15, Stryker, US). 5-second segments with stable and CPR artefact free signals were extracted (Figure). The circulation component of the TI signal (Figure, red line) was extracted using a Kalman smoother. Ten waveform features were computed per segment and fed into a random forest regressor to predict systolic and diastolic arterial pressures (SAP, DAP), their difference (DifAP) and area of the IBP signal (ArAP). Pearson correlation coefficients between the regression model and the IBP metrics were computed. Data were divided by patient into training/test sets to fit and evaluate the model, respectively, and the process was repeated 500 times. Results: 235 minutes (2261 segments) were extracted with median (Q1-Q3) values of 71.3(39.2-88.1) mmHg for SAP, 44.2(30.0-50.0) mmHg for DAP, 25.6(7.1-38.8) mmHg for DifAP and 63.4(17.0-85.9) mmHg*sec for ArAP. The correlation coefficients between TI-predicted and IBP-measured SAP, DAP, DifAP and ArAP were 0.62 (0.49-0.72), 0.36 (0.22-0.49), 0.69 (0.57-0.76) and 0.64 (0.50-0.73), respectively. Conclusions: Different hemodynamic phases can be observed in both TI and IBP (Figure). TI-based predictions showed good correlation with IBP measures. This could lead to new non-invasive methods to monitor different phases of circulation based on the TI.

scholarly journals Clinical and laboratory findings related to a favorable evolution of hantavirus pulmonary syndrome

2006 ◽  
Vol 39 (3) ◽  
pp. 237-240 ◽  
Author(s):  
Rodrigo de Carvalho Santana ◽  
Gelse Mazzoni Campos ◽  
Luís Tadeu Moraes Figueiredo ◽  
José Fernando de Castro Figueiredo
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Invasive Mechanical Ventilation ◽  
Blood Gases ◽  
Favorable Outcome ◽  
Hantavirus Pulmonary Syndrome ◽  
Inotropic Agents ◽  
Laboratory Findings ◽  
Arterial Blood ◽  
Systolic Arterial Blood Pressure

The medical records of 27 patients with hantavirus pulmonary syndrome were analyzed according to the need for invasive mechanical ventilation in relation to the following data up on hospital admission: age, gender, fever, cough, dyspnea, systolic arterial blood pressure, heart rate, levels of hemoglobin, hematocrit, leukocytes, lymphocytes, platelets, creatinine and arterial blood gases. The volume infused during the first 24 hours after admission, the use of inotropic agents, the use of corticosteroids and the patient outcomes were also evaluated. A favorable outcome was related to systolic blood pressure³ 100mmHg, heart rate lower than 100 beats per minute, creatinine below 1.6mg/dl, arterial blood pH³ 7.35, bicarbonate higher than 15mEq/dl, oxygen saturation higher than 84.1%, lower rehydration volume in the first 24 hours of hospitalization and no use of inotropic agents. Absence of clinical and laboratory signs of circulatory shock up on admission was associated with a favorable outcome of the patients.

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