scholarly journals Refractory Paroxysmal Sympathetic Hyperactivity Following Traumatic Intracerebral Hemorrhage

Cureus ◽  
2021 ◽  
Author(s):  
Matea Malinovic ◽  
Kristine Kallenberger ◽  
Justin Sandall
Keyword(s):  
Intracerebral Hemorrhage ◽  
Sympathetic Hyperactivity ◽  
Paroxysmal Sympathetic Hyperactivity

Risk factors and clinical features of paroxysmal sympathetic hyperactivity after spontaneous intracerebral hemorrhage

2020 ◽  
Vol 225 ◽  
pp. 102643
Author(s):  
Zhenxing Li ◽  
Wen Chen ◽  
Yibai Zhu ◽  
Kaiwei Han ◽  
Junyu Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intracerebral Hemorrhage ◽  
Clinical Features ◽  
Spontaneous Intracerebral Hemorrhage ◽  
Sympathetic Hyperactivity ◽  
Paroxysmal Sympathetic Hyperactivity

scholarly journals Cerebral fat embolization with paroxysmal sympathetic hyperactivity syndrome and septic shock at high altitude: a case report and literature review

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Min Li ◽  
Gang Zhu ◽  
Hao Guo ◽  
Shun Nan Ge ◽  
Guo Dong Gao ◽  
...  
Keyword(s):  
Septic Shock ◽  
Differential Diagnosis ◽  
Case Report ◽  
Literature Review ◽  
High Altitude ◽  
Fat Embolism ◽  
Neurological Rehabilitation ◽  
Case Presentation ◽  
Sympathetic Hyperactivity ◽  
Paroxysmal Sympathetic Hyperactivity

AbstractBackgroundCerebral fat embolism (CFE) syndrome at high altitude was rare complicated with paroxysmal sympathetic hyperactivity (PSH) syndrome and septic shock. It is a challenge to differential diagnosis and treatment at high altitude.Case presentationThis case presents a CFE with PSH and septic shock of a 23-year-old man occurred at high altitude of 3800 m above sea level, transferred by airplane successfully and cured in the department of neurosurgery, Xi’an Tangdu Hospital.ConclusionsIt is key that CFE with PSH can be rapid diagnosed and treatment bundles of septic shock should be initiated as soon as possible. Early neurological rehabilitation played an important role for good outcome.

scholarly journals P88 Paroxysmal sympathetic storm and the role of beta-blockers in traumatic brain injury: a scoping review protocol

BJS Open ◽  
2021 ◽  
Vol 5 (Supplement_1) ◽  
Author(s):  
Stéphane Nguembu ◽  
Marco Meloni ◽  
Geneviève Endalle ◽  
Hugues Dokponou ◽  
Olaoluwa Ezekiel Dada ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Length Of Stay ◽  
Glasgow Coma Scale ◽  
Scoping Review ◽  
Beta Blockers ◽  
Clinical Signs ◽  
Sympathetic Hyperactivity ◽  
Paroxysmal Sympathetic Hyperactivity

Abstract Introduction Most cases of paroxysmal sympathetic hyperactivity (PSH) result from traumatic brain injury (TBI). Little is known about its pathophysiology and treatment, and several neuroprotective drugs are used including beta-blockers. The aim of our study is to collate existing evidence of the role of beta-blockers in the treatment of PSH. Method We will search MEDLINE, Web of Science, EMBASE, Cochrane, and Google Scholar. The search terms used will cover the following terms: “paroxysmal sympathetic hyperactivity”, “traumatic brain injury” and “beta-blockers.”: No language or geographical restrictions will be applied. Two independent co-authors will screen the titles and abstracts of each article following predefined inclusion and exclusion criteria. If there is a conflict the two reviewers will find a consensus and if they cannot a third co-author will decide. Using a pre-designed and pre-piloted data extraction form, data from each included citation will be collected (authors identification, study type, TBI severity, type of beta-blockers used, dosage of the drug, clinical signs of PSH, Glasgow Coma Scale, Glasgow Outcome Scale, mortality, morbidity and length of stay). Simple descriptive data analyses will be performed and the results will be presented both in a narrative and tabular form. Results The effectiveness of beta-blockers in post-TBI PHS will be evaluated through clinical signs of PHS(increased heart rate, respiratory rate, temperature, blood pressure, and sweating), Glasgow Coma Scale, and Glasgow Outcome Scale. mortality, morbidity and length of stay. Conclusion At the end of this scoping review we will design a systematic review with metaanalysis if there are a reasonable number of studies otherwise we will design a randomized controlled trial.

scholarly journals Decreasing incidence of paroxysmal sympathetic hyperactivity syndrome in the vegetative state

2012 ◽  
Vol 44 (6) ◽  
pp. 502-504 ◽  
Author(s):  
L Pignolo ◽  
S Rogano ◽  
M Quintieri ◽  
E Leto ◽  
G Dolce
Keyword(s):  
Vegetative State ◽  
Sympathetic Hyperactivity ◽  
Paroxysmal Sympathetic Hyperactivity

scholarly journals Storms and silence: a case report of catatonia and paroxysmal sympathetic hyperactivity following cerebral hypoxia

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Dallas Wolfgang Hamlin ◽  
Nuzhat Hussain ◽  
Aum Pathare
Keyword(s):  
Gold Standard ◽  
Neuropsychiatric Symptoms ◽  
Altered Mental Status ◽  
Symptom Clusters ◽  
Opioid Overdose ◽  
Cerebral Hypoxia ◽  
Case Presentation ◽  
Sympathetic Hyperactivity ◽  
Paroxysmal Sympathetic Hyperactivity ◽  
Related Symptom

Abstract Background Delayed Post Hypoxic Leukoencephalopathy (DPHL) is a syndrome that occurs after hypoxia, and can present with a variety of neuropsychiatric symptoms, including catatonia and paroxysmal sympathetic hyperactivity (PSH). The gold standard for the treatment of catatonia is electroconvulsive therapy (ECT). However, ECT can exacerbate the paroxysms of sympathetic hyperactivity and complicate recovery from DPHL. The treatment of PSH is not well established. Case presentation We present a case of a patient with multiple opiate overdoses who presented with altered mental status. He was diagnosed with catatonia and subsequently treated with ECT. His clinical condition worsened, and a revised diagnosis of PSH was established. The patient’s condition improved with medical management. Conclusion This case highlights the need to distinguish between these two related symptom clusters, as the incidence of DPHL and opioid overdose related neuropsychiatric problems increase. This distinction can greatly influence the course of treatment, and the need to consider alternative treatments.

S82. Paroxysmal sympathetic hyperactivity evident as cyclical pattern on quantitative EEG analysis

2018 ◽  
Vol 129 ◽  
pp. e172-e173
Author(s):  
Jennifer Percy ◽  
Ognen A. Petroff ◽  
Aline Herlopian
Keyword(s):  
Quantitative Eeg ◽  
Eeg Analysis ◽  
Sympathetic Hyperactivity ◽  
Paroxysmal Sympathetic Hyperactivity ◽  
Cyclical Pattern ◽  
Quantitative Eeg Analysis
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