scholarly journals Wiener Filter Used in the EBT2 Film for Radiation Therapy

Author(s):  
Liyun Chang
2016 ◽  
Vol 33 (6) ◽  
pp. 1742-1752
Author(s):  
Liyun Chang ◽  
Yi-Chun Du

Purpose – EBT2 film, a convenient quality assurance (QA) tool with high 2D dosimetry resolution, has been widely used in the dosimetry application of radiation therapy with lots of benefits especially its self-development, water equivalent, energy independent and high spatial resolution. However, the higher inhomogeneity between the pixels of EBT2 image, needed to be averaged out according to the traditional method, but it could sacrifice the spatial resolution. To solve this problem, the purpose of this paper is to introduce a Wiener filter (WF) technique applied with a multi-channel (MC) method. Design/methodology/approach – The EBT2 film was calibrated by using the percentage depth dose method combined with the WF technique and a MC method. Then the calculated film doses were compared with the measurement doses by the edge detector with the water phantom. Findings – With high spatial resolution to be 0.2 mm, the results demonstrate that the EBT2 film calibration through both of the WF technique and MC method has higher accuracy (within 2 percent) and lower uncertainty. Originality/value – A new technique of WF with MC method was presented to calibrate the dosimetry system of EBT2 film. With high spatial resolution (0.2 mm), the studies show that the combination of WF technique with MC method can have high accuracy with low noises to calibrate EBT2 film. This method can also be applied to all the QAs of treatment planning of radiation therapy by using the EBT2 film.


2013 ◽  
Vol 40 (6Part15) ◽  
pp. 276-276
Author(s):  
M Hadsell ◽  
R Ger ◽  
C Inscoe ◽  
J Lu ◽  
S Chang ◽  
...  

2013 ◽  
Vol 40 (6Part4) ◽  
pp. 117-117 ◽  
Author(s):  
M Hadsell ◽  
R Ger ◽  
C Inscoe ◽  
E Schreiber ◽  
J Lu ◽  
...  

Author(s):  
Joachim Frank

Cryo-electron microscopy combined with single-particle reconstruction techniques has allowed us to form a three-dimensional image of the Escherichia coli ribosome.In the interior, we observe strong density variations which may be attributed to the difference in scattering density between ribosomal RNA (rRNA) and protein. This identification can only be tentative, and lacks quantitation at this stage, because of the nature of image formation by bright field phase contrast. Apart from limiting the resolution, the contrast transfer function acts as a high-pass filter which produces edge enhancement effects that can explain at least part of the observed variations. As a step toward a more quantitative analysis, it is necessary to correct the transfer function in the low-spatial-frequency range. Unfortunately, it is in that range where Fourier components unrelated to elastic bright-field imaging are found, and a Wiener-filter type restoration would lead to incorrect results. Depending upon the thickness of the ice layer, a varying contribution to the Fourier components in the low-spatial-frequency range originates from an “inelastic dark field” image. The only prospect to obtain quantitatively interpretable images (i.e., which would allow discrimination between rRNA and protein by application of a density threshold set to the average RNA scattering density may therefore lie in the use of energy-filtering microscopes.


2007 ◽  
Vol 177 (4S) ◽  
pp. 153-154
Author(s):  
Sean P. Stroup ◽  
Brian K. Auge ◽  
James O. L'Esperance ◽  
Jennifer Cullen ◽  
Song Kang

2007 ◽  
Vol 177 (4S) ◽  
pp. 131-132 ◽  
Author(s):  
Jochen Wafz ◽  
Andrea Gallina ◽  
Aldo M. Bocciardi ◽  
Sascha Ahyai ◽  
Paul Perrotta ◽  
...  

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