Acetylcholinesterase Inhibitory Activity and Antiamyloidogenic Effect of Cercis chinensis Bunge Seed Ethanolic Extract

2021 ◽  
Vol 29 (5) ◽  
pp. 337-344
Author(s):  
Ju Eun Kim ◽  
Jae Yoon Leem
Keyword(s):  
Inhibitory Activity ◽  
Ethanolic Extract ◽  
Acetylcholinesterase Inhibitory Activity

New Cycloartane-type Triterpenoids from Artocarpus nobilis

2007 ◽  
Vol 62 (2) ◽  
pp. 280-284 ◽  
Author(s):  
Shamsulhaq Zahid ◽  
Athar Ata ◽  
Radhika Samarasekera
Keyword(s):  
Sri Lanka ◽  
Inhibitory Activity ◽  
Ethanolic Extract ◽  
Spectroscopic Studies ◽  
Acetylcholinesterase Inhibitory Activity ◽  
New Compounds ◽  
Phytochemical Studies

Recent phytochemical studies on the ethanolic extract of Artocarpus nobilis, collected from Sri Lanka, have resulted in the isolation of two new cycloartane-type triterpenoids, artocarpuate A (1) and artocarpuate B (2). Structures of these new compounds were established with the aid of extensive NMR spectroscopic studies. Compounds 1 and 2 were found to exhibit weak acetylcholinesterase inhibitory activity.

Bromotyrosine alkaloids with acetylcholinesterase inhibitory activity from the Thai sponge Acanthodendrilla sp.

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
N Sirimangkalakitti ◽  
M Yokoya ◽  
K Changwichit ◽  
T Saesong ◽  
OJ Olatunji ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Acetylcholinesterase Inhibitory Activity

Inhibitory Activity of Asana, Heartwood of Pterocarpus marsupium, Against Xanthine Oxidase

2019 ◽  
Vol 14 (12) ◽  
pp. 1934578X1988789
Author(s):  
Takahiro Deguchi ◽  
Yusuke Hata ◽  
Atsushi Tamai ◽  
Moe Yamamoto ◽  
Takanori Fujita ◽  
...  
Keyword(s):  
Liquid Chromatography ◽  
Xanthine Oxidase ◽  
Inhibitory Activity ◽  
Soluble Fraction ◽  
Ethanolic Extract ◽  
Modern Medicine ◽  
Noncommunicable Disease ◽  
Promising Candidate ◽  
Pterocarpus Marsupium ◽  
Novel Agent

The heartwood of Pterocarpus marsupium is called as “Asana” in Ayurveda. Its aquatic infusion was used for treating “prameha,” which indicates a polyuria disease in modern medicine. In our research program to investigate a novel agent to improve hyperuricemia, we focused on the extract of Asana as a xanthine oxidase (XOD) inhibitor. Asana extract (50% ethanolic extract, PM-ext) showed 11%, 35%, and 38% inhibition at 50, 200, and 500 µg/mL, respectively. Subsequently, PM-ext was partitioned with ethyl acetate (AcOEt), butanol, and water. Among them, AcOEt-soluble fraction indicated the most potent XOD inhibitory activity and was consecutively fractionated using various liquid chromatography to obtain liquiritigenin (1), isoliquiritigenin (2), and marsupsin (3) as active principles. Compound 1 showed 16% inhibition at 200 µM while 2 showed 20%, 32%, and 46% inhibition at 50, 100, and 200 µM, respectively. Compound 3 showed 15% inhibition at 500 µM. This is the first report on the XOD inhibitory activity of 3. From these results, PM-ext is a promising candidate material for improvement of hyperuricemia. Here, Asana was recognized as an effective material against noncommunicable disease and is expected to be developed as a functional ingredient.

Synthesis and acetylcholinesterase inhibitory activity of huperzine A—E2020 combined compound

1999 ◽  
Vol 9 (23) ◽  
pp. 3279-3284 ◽  
Author(s):  
Fanxing Zeng ◽  
Hualiang Jiang ◽  
Yufeng Zhai ◽  
Haiyan Zhang ◽  
Kaixian Chen ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Huperzine A ◽  
Acetylcholinesterase Inhibitory Activity
Sign in / Sign up

Export Citation Format

Share Document