scholarly journals Tuberculosis Vaccine Development: Current Status and Future Directions

2019 ◽  
Author(s):  
Kaushik Bharati
Keyword(s):  
Vaccine Development ◽  
Current Status ◽  
Future Directions

Vaccine against scabies: necessity and possibility

Parasitology ◽  
2014 ◽  
Vol 141 (6) ◽  
pp. 725-732 ◽  
Author(s):  
XIAOSONG LIU ◽  
SHELLEY WALTON ◽  
KATE MOUNSEY
Keyword(s):  
Infectious Disease ◽  
Vaccine Development ◽  
Sarcoptes Scabiei ◽  
Current Status ◽  
Industrialized Countries ◽  
Future Directions ◽  
Immunological Mechanisms

SUMMARYScabies is an infectious disease that is endemic in poorly resourced communities, and also common in industrialized countries. Although the disease, which is caused by infestation of Sarcoptes scabiei, is generally mild, the need for a vaccine against S. scabiei is proposed. The immunological mechanisms that control S. scabiei infection are discussed and the current status of scabies vaccine development reviewed. Future directions for scabies vaccine development are also addressed.

scholarly journals A Mini Review on COVID-19 Therapeutics: Current Status and Future Directions

Coronaviruses ◽  
2021 ◽  
Vol 02 ◽  
Author(s):  
Niranjan Kaushik ◽  
Vikram Sharma ◽  
Vikas Sharma
Keyword(s):  
Vaccine Development ◽  
Mobile Apps ◽  
Review Article ◽  
Current Status ◽  
Future Directions ◽  
Natural Sources ◽  
The Family ◽  
First Time ◽  
Corona Viruses ◽  
Harmful Effects

Abstract:: Corona viruses belong to the family Coronaviridae. This pandemic has surprised every human being as many of us facing a pandemic first time in our life. Moreover, absence of a drug or therapy for this disease further aggravates its harmful effects. As a result, world is now preparing to find out a possible therapy against this disease to stop further growth of this pandemic. Some of these therapies include vaccine development, drug development along with possible drugs from natural sources. In this review article, the focus is on current status of research against virus responsible for current pandemic, various mobile apps launched to check spread of viral infection and status of prospective therapies available against this virus.

Current Status and Future Directions of Nanoparticulate Strategy for Cancer Immunotherapy

2016 ◽  
Vol 17 (8) ◽  
pp. 755-762 ◽  
Author(s):  
Xu Zhou ◽  
Renhe Liu ◽  
Shuo Qin ◽  
Ruilian Yu ◽  
Yao Fu
Keyword(s):  
Cancer Immunotherapy ◽  
Current Status ◽  
Future Directions

Shigella Vaccine Development: Prospective Animal Models and Current Status

2014 ◽  
Vol 14 (10) ◽  
pp. 903-912 ◽  
Author(s):  
Yeon-Jeong Kim ◽  
Sang-Gu Yeo ◽  
Jae-Hak Park ◽  
Hyun-Jeong Ko
Keyword(s):  
Animal Models ◽  
Vaccine Development ◽  
Current Status

scholarly journals New Approaches for the Treatment of Chronic Graft-Versus-Host Disease: Current Status and Future Directions

2020 ◽  
Vol 11 ◽  
Author(s):  
Nathaniel Edward Bennett Saidu ◽  
Chiara Bonini ◽  
Anne Dickinson ◽  
Magdalena Grce ◽  
Marit Inngjerdingen ◽  
...  
Keyword(s):  
Graft Versus Host Disease ◽  
Current Status ◽  
Future Directions ◽  
Host Disease ◽  
Graft Versus Host ◽  
New Approaches

scholarly journals Current Status of Human Papillomavirus-Related Head and Neck Cancer: From Viral Genome to Patient Care

2021 ◽  
Author(s):  
Haoru Dong ◽  
Xinhua Shu ◽  
Qiang Xu ◽  
Chen Zhu ◽  
Andreas M. Kaufmann ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Head And Neck ◽  
Treatment Strategies ◽  
Hpv Infection ◽  
Immune Checkpoint Blockade ◽  
Current Status ◽  
Future Directions ◽  
Sequencing Technologies ◽  
E6 And E7 ◽  
The Continuum

AbstractHuman papillomavirus (HPV) infection identified as a definitive human carcinogen is increasingly being recognized for its role in carcinogenesis of human cancers. Up to 38%–80% of head and neck squamous cell carcinoma (HNSCC) in oropharyngeal location (OPSCC) and nearly all cervical cancers contain the HPV genome which is implicated in causing cancer through its oncoproteins E6 and E7. Given by the biologically distinct HPV-related OPSCC and a more favorable prognosis compared to HPV-negative tumors, clinical trials on de-escalation treatment strategies for these patients have been studied. It is therefore raised the questions for the patient stratification if treatment de-escalation is feasible. Moreover, understanding the crosstalk of HPV-mediated malignancy and immunity with clinical insights from the proportional response rate to immune checkpoint blockade treatments in patients with HNSCC is of importance to substantially improve the treatment efficacy. This review discusses the biology of HPV-related HNSCC as well as successful clinically findings with promising candidates in the pipeline for future directions. With the advent of various sequencing technologies, further biomolecules associated with HPV-related HNSCC progression are currently being identified to be used as potential biomarkers or targets for clinical decisions throughout the continuum of cancer care.

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