scholarly journals Clinical Nature and Treatment with Sclerotherapy of Pyogenic Granuloma: A Case Series

Author(s):  
Jigna S Shah ◽  
Anand Patel ◽  
Nutan Lunagariya

Pyogenic granuloma is a misnomer, as in reality it arises in response to various irritating factors such as low-grade local irritation or hormonal factors, traumatic injury as well as presented as inflammatory hyperplasia that is not related to infection. Oral pyogenic granuloma is a lobulated or smooth exophytic lesion with pedunculated or sometimes sessile base, haemorrhagic in tendency. Although excisional surgery is the treatment of choice for it, some other treatment protocols such as laser therapy, sclerotherapy with 3% polidocanol, cryotherapy and steroid therapy have also been proposed. Here, Authors present a case series of gingival as well as extra gingival pyogenic granulomas which were diagnosed and treated by various therapies i.e., surgical excision, Carbon Dioxide (CO2) laser therapy and sclerotherapy. Regression period of lesion with different therapies was evaluated in detail. Maximum patients were female in the age group of 26-50 years in present case series. Almost all cases of pyogenic granuloma had typical clinical characteristic without bony alteration. Amongst all therapies sclerotherapy had the biggest advantage of less regression period for any case of pyogenic granuloma i.e., 7-8 days only.

2017 ◽  
Vol 5 (2) ◽  
pp. 112
Author(s):  
Gaurav Mahajan ◽  
Aditi Gautam

Pyogenic granuloma is one of the inflammatory hyperplasias seen in the oral cavity. This term is a misnomer because the lesion is unrelated to infection and in reality arises in response to various stimuli such as low- grade local irritation, traumatic injury or hormonal factors. The clinical diagnosis of such lesion can be quite challenging because of its close resemblance to certain malignancies like peripheral giant cell granuloma, kaposi’s sarcoma, non hodgkin’s lymphoma etc. for excisional biopsy, options available are conventional surgical excision, electrocautery or lasers. In this report, we seek to highlight the therapeutic advantages achieved with a soft tissue diode laser in the treatment of pyogenic granuloma.


2020 ◽  
Vol 6 (1) ◽  
pp. 56-59
Author(s):  
Suraj Pandey ◽  
Ashish Saini ◽  
Sunil Chandra Verma ◽  
Pranav Kumar Singh

Pyogenic granuloma (PG) is one of the inflammatory hyperplasias seen in the oral cavity. This term is a misnomer because the lesion is unrelated to infection and in reality arises in response to various stimuli such as low-grade local irritation, traumatic injury or hormonal factors. PG is predominantly seen in the second decade of life in young adult females. PGs generally are soft, painless, and deep red to reddish-purple in colour. It shows a striking predilection for the maxillary anterior area. Also, the majority of PGs are found on the marginal gingiva with only 15% of the tumours on the alveolar part. There are two kinds of PG namely lobular capillary hemangioma (LCH type) and non-LCH type, which manifest as distinct entities and differ in many aspects. Although excisional surgery is the treatment of choice for it, some other treatment protocols such as the use of Nd:YAG laser, flash lamp pulsed dye laser, cryosurgery, intralesional injection ofethanol or corticosteroid and sodium tetradecylsulfatesclerotherapy have been proposed. We hereby present a rare case report of lobular capillary hemangioma occurring in the maxillary posterior region. Also, contrary to its site specificity, it involved the attached gingiva and alveolar mucosa, thereby presenting a diagnostic dilemma. The various differences between the LCH and Non-LCH type PG are also discussed emphasising their different pathways of evolution.  


2012 ◽  
Vol 2012 ◽  
pp. 1-3
Author(s):  
B. Chandrashekar

Pyogenic granuloma is one of the inflammatory hyperplasia seen in the oral cavity. The term is a misnomer because it is not related to infection and arises in response to various stimuli such as low-grade local irritation, traumatic injury, or hormonal factors. It is most commonly seen in females in their second decade of life due to vascular effects of hormones. Although excisional surgery is the treatment of choice for it, this paper presents the safest and most minimally invasive procedure for the regression of pyogenic granuloma.


Author(s):  
Rithul P ◽  
◽  
Rao PK ◽  
Kini R ◽  
Gonsalvis N ◽  
...  

Pyogenic granuloma is one of the inflammatory hyperplasias seen in the oral cavity. This term is a misnomer because the lesion is unrelated to infection and in reality arises in response to various stimuli such as low-grade local irritation, traumatic injury or hormonal factors. Clinically, oral pyogenic granuloma is a smooth or lobulated exophytic lesion manifesting as small, red erythematous papules on a pedunculated or sometimes sessile base, which is usually hemorrhagic. The surface ranges from pink to red to purple, depending on the age of the lesion Conservative surgical excision is usually curative but recurrence is not unusual. Lasers and cryotherapy may also be employed.


2015 ◽  
Vol 5 (1) ◽  
pp. 26-29
Author(s):  
Md Ashif Iqbal ◽  
Jesmin Mohol ◽  
Md Saifur Rahman ◽  
Fayeza Afrin

Pyogenic granuloma is one of the inflammatory hyperplasia seen in the oral cavity. This term is a misnomer because the lesion is unrelated to infection and in reality arises in response to various stimuli such as low- grade local irritation, traumatic injury or hormonal factors. Clinically, oral pyogenic granuloma is a smooth or lobulated exophytic lesion manifesting as small, red erythematous papules on a pedunculated or sometimes sessile base, which is usually hemorrhagic. The surface ranges from pink to red to purple, depending on the age of the lesion. Because of the high frequency of pyogenic granuloma in the oral cavity, especially during pregnancy, and necessity for proper diagnosis and treatment, a complete information and investigations about this lesion, in addition its treatment is presented. The study emphasizes the clinical follow-up after the treatment of patients that present pyogenic granuloma. Follow-up over 19 months of surgical procedures demonstrated the maintenance of a periodontal health decreases the chances of recurrence.Update Dent. Coll. j: 2015; 5 (1): 26-29


2020 ◽  
Vol 48 (02) ◽  
pp. 72-78
Author(s):  
Patricia Balvís-Balvís ◽  
Javier Yañez-Calvo ◽  
Manuel Castro-Menéndez ◽  
María José Ferreirós-Conde

Abstract Objective Giant lipomas are benign tumors larger than 5 cm in size that are very uncommun in the hand, with the extant literature limited to case reports and small case series. The aim of the present study is to describe our experience with giant lipomas at the level of the hand, reviewing the most important aspects in relation to their diagnosis and treatment. Material and Methods We present 6 patients treated in our service with giant lipomas of the hand between 2007 and 2015. Four cases only presented difficulty in grasping and mobilizing the hand due to the large size of the lipoma. Two cases were accompanied by a clinical feature of compression of the median nerve in relation to its location within the carpal tunnel. Results All patients underwent surgery, and a complete excision of the lipoma was performed. The functional results have been satisfactory in all cases. Conclusions Giant lipomas of the hand are infrequent tumors of slow growth, generally asymptomatic, although they can cause a compressive pathology due to the great size that they reach. Magnetic resonance imaging is an especially useful test to locate and accurately determine the size of the lesion in view of its surgical excision. After surgery, it is important to make a differential diagnosis with low-grade liposarcomas through an anatomopathological study, since both, macroscopically, have similar characteristics.


2009 ◽  
Vol 133 (12) ◽  
pp. 1989-1993 ◽  
Author(s):  
Zaher I. Chakhachiro ◽  
Ghazi Zaatari

Abstract Solid-pseudopapillary neoplasm of the pancreas is a relatively uncommon tumor. It typically affects young women, has nonspecific clinical and radiologic manifestations, and can be readily diagnosed by ultrasound-guided fine-needle aspiration and histopathologic evaluation. Histologic features characteristically show loosely cohesive, relatively uniform polygonal cells surrounding delicate capillary-sized blood vessels. Other features include cytoplasmic vacuolization, finely stippled chromatin, nuclear grooving, eosinophilic hyaline globules, and degenerative changes. Almost all solid-pseudopapillary neoplasms harbor mutations in the β-catenin gene. They stain with β-catenin, CD10, and focally with neuroendocrine markers. Although previously considered benign, this tumor is currently considered a low-grade malignant epithelial neoplasm with low metastatic rate and high overall survival. Most patients are cured by complete surgical excision. Despite the characterization of the morphologic and molecular features of this enigmatic neoplasm, more work is needed to uncover its cell of origin and true histogenesis.


2014 ◽  
Vol 8 (3) ◽  
pp. 169-171
Author(s):  
A Agarwal ◽  
HS Bhattacharya ◽  
Manjunath RG Shiva ◽  
ST Gokhle

ABSTRACT Pyogenic granuloma is a reactive lesion. It usually arises in response to various stimuli such as low-grade local irritation, traumatic injury, hormonal factors, or certain kinds of drugs hyperplasia of connective tissue in response to local irritants. Gingiva is the most common site affected followed by buccal mucosa, tongue and lips. It is a tumourlike growth of the oral cavity, frequently located surrounding the anterior teeth Histologically, the surface epithelium may be intact, or may show foci of ulcerations or even exhibiting hyperkeratosis. Pyogenic granuloma should be excised along with the base and its causative factors. This paper presents a case of a pyogenic granuloma managed by surgical intervention.


2018 ◽  
Vol 56 (1) ◽  
pp. 43-49 ◽  
Author(s):  
Silvia Sabattini ◽  
Giuliano Bettini

Cutaneous mast cell tumors (cMCTs) account for approximately 20% of skin neoplasms in cats. As there is no grading system for these tumors, prognosis is difficult to estimate. Although the typical presentation is a benign tumor that can be cured by surgical excision, a small but important proportion of feline cMCTs is biologically aggressive and can spread to local lymph nodes, precede the onset of disseminated cutaneous disease, or be associated with visceral involvement. A number of macroscopic and histologic features were retrospectively evaluated in cases of feline cMCTs treated with surgical excision with or without medical therapy. Cats were divided into 2 groups based on the clinical outcome. Group 1 included cats alive with no mast cell tumor–related disease at 1000 days from surgery; group 2 included cats developing histologically confirmed metastatic or cutaneous disseminated disease. The criteria allowing the best differentiation between the groups were used to develop a grading scheme. Groups 1 and 2 were composed by 48 (76%) and 15 (24%) cases, respectively. Tumors were classified as high grade if there were >5 mitotic figures in 10 fields (400×) and at least 2 of the following criteria: tumor diameter >1.5 cm, irregular nuclear shape, and nucleolar prominence/chromatin clusters. According to this scheme, the 15 (24%) high-grade cMCTs had significantly reduced survival time (median, 349 days; 95% CI, 0–739 days) as compared with the 48 low-grade tumors (median not reached; P < .001). Further studies are warranted to validate this grading system and test reproducibility on a larger case series.


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