scholarly journals A Rare Case of Malignant Transformation of Keratinous Cyst in Gluteal Region

Author(s):  
BS Balapriya ◽  
R Anantharamakrishnan ◽  
K Senthil Kumar ◽  
Femela Muniraj ◽  
Vijayashree Raghavan

Keratinous cyst (Epidermoid cysts) is more common and frequently encountered. It is one of the commonest benign lesion. Malignant transformation of keratinous (epidermoid) cyst is very rare. Epidermal cyst is noted as non-malignant condition. Few cases have shown malignant transformation of keratinous cyst into Squamous Cell Carcinoma (SCC). Here, authors report a rare case of 49-year-old male who presented with long standing keratinous cyst in gluteal region which turned out as SCC 35 years after intial presentation of the leison, and here authors have discussed the clinicopathological features of this rare entity. Hence, any swelling which is long standing, showing sudden increase in size, progressing symptoms, more than 2 cm in diameter, cyst content seen as heterogenous pattern on imaging should be highly suspicious of malignancy.

2012 ◽  
Vol 4 (2) ◽  
pp. 329-332 ◽  
Author(s):  
R Sitaula Kharel ◽  
S Bhatta ◽  
G B Shrestha ◽  
J K Shrestha

Background: Kissing nevus is a congenital nevus in adjacent parts of the eyelids. Malignant transformation of kissing or divided nevi of the eyelids is rarely described. Objective: To report a very rare case of malignant transformation of kissing nevus with ocular and extraocular spread. Case: A 57- year- old man with 6/6 visual acuity in both eyes presented with a kissing nevus present since birth in right upper and lower eyelids which had a slow growth phase. The upper lid in the area of the nevus was thickened with a 20x12x15 mm black pigmented crusted hemorrhagic nodular lesions. The lower lid had a 6 mm black pigmented ulcerated lesion over the pre-existing nevus in the lateral third of the lid with full thickness infiltration. Another 5x4 mm pigmented lesion over the lower medial lid margin with a thickness of about 3 mm extended to the conjunctival side of the lower lid. Right sided pre-auricular and submaxillary nodes were palpable. A biopsy of tissue samples from the eyelid and pre-auricular nodes were consistent with malignant melanoma.Conclusion: Malignant transformation of kissing nevus is rare. It can spread to the conjunctiva, pre-auricular and sub-mandibular lymphnodes.DOI: http://dx.doi.org/10.3126/nepjoph.v4i2.6555 Nepal J Ophthalmol 2012; 4 (2): 329-332  


Author(s):  
Neeraj Bansal ◽  
Ankita Vergadia ◽  
A. N. Mashke ◽  
Aashirwad Datey

Epidermoid cysts are commonly called as sebaceous cysts that mostly occur in the subcutaneous plain. Giant epidermoid cysts are rare and generally greater than 5 cm in size. Few cases of malignant transformation of the sebaceous cysts have also been reported in literature.


Chirurgia ◽  
2019 ◽  
Vol 32 (5) ◽  
Author(s):  
Anestis A. Charalampopoulos ◽  
Kostantinos G. Kopanakis ◽  
Vasileios C. Kollaras ◽  
Dimitrios C. Papakonstantinou ◽  
Nikolaos N. Koliakos ◽  
...  

Author(s):  
Abhinav Srivastava ◽  
Ranjan Agrawal ◽  
Prashant Bhardwaj

ABSTRACT Epidermoid cysts are common lesions, but malignant transformation of their epithelium is rare. There are few case reports in the literature concerning malignant transformation of an epidermal cyst into squamous cell carcinoma. Two epidermoid cysts occurring simultaneously in the neck is rare and not a single case report is available in the literature. One of the cysts transforming into squamous cell carcinoma and the other showing atypical changes is still the rarest and not reported till date. We present a case of two epidermal inclusion cysts in a patient out of which there were atypical changes in one cyst and other cyst showed squamous cell carcinoma. How to cite this article Mohan C, Srivastava A, Agrawal R, Bhardwaj P. A Rare Case of Epidermoid Cyst in Neck. Int J Adv Integ Med Sci 2016;1(1):15-17.


2021 ◽  
pp. 171-175
Author(s):  
Yuichi Kurihara ◽  
Koji Kawamura ◽  
Masutaka Furue

The coexistence of epidermal cysts and lipomas at the same site is extremely rare, although epidermal cysts and lipomas are both common benign skin tumors. We present a rare case of an epidermal cyst with underlying lipoma on the back. This case report may simply be a result of coincidence, but the possibility of underlying subcutaneous tumors should be considered before epidermal cyst surgery.


BMC Urology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
B. Heijkoop ◽  
D. Bolton ◽  
D. Katz ◽  
Andrew Ryan ◽  
J. Epstein ◽  
...  

Abstract Background Primary Seminal Vesicle (SV) tumours are a rare entity, with most SV masses representing invasion of the SV by malignancy originating in an adjacent organ, most often the prostate. Previously reported primary SV epithelial tumours have included adenocarcinoma and cystadenoma, with limited prior reports of inracystic papillary structures. Case presentation A 35-year-old male presented with azoospermia, intermittent macroscopic haematuria, and mild right iliac fossa and groin pain. A papillary appearing seminal vesicle mass was found on imaging and seminal vesicoscopy. The mass was robotically excised with diagnosis of benign cystic papillary adenoma made. Conclusion In this manuscript we describe a rare case of a benign cystic papillary adenoma of the seminal vesicle, a unique histological entity differentiated from cystadenoma of the Seminal Vesicle by its papillary component.


2017 ◽  
Vol 2017 ◽  
pp. 1-5
Author(s):  
N. Srikant ◽  
Shweta Yellapurkar ◽  
Karen Boaz ◽  
Mohan Baliga ◽  
Nidhi Manaktala ◽  
...  

Polycystic (dysgenetic) disease of the salivary glands is a rare entity that has only recently been described in the literature. The disease is more commonly seen in females and majority of the cases have presented as bilateral parotid gland swellings. This case presenting in a 21-year-old male is the first of this unusual entity involving solely the minor salivary gland on the lower lip. This case report highlights the importance for the clinician to be aware of this differential diagnosis, when treating an innocuous lesion like a mucocele.


2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S51-S51
Author(s):  
Erika Egal ◽  
Welligton Sabino ◽  
João Scarini ◽  
Reydson Souza ◽  
Albina Altemani ◽  
...  

Abstract Introduction Pleomorphic adenoma (PA) is a benign lesion of the salivary glands that can suffer malignant transformation to carcinoma ex adenoma pleomorphic (CXPA). The pathogenesis of CXPA has been attributed to the accumulation of genetic disorders in preexisting PAs. However, there is no confirmation whether there is a common target gene involved in all histopathological subtypes or the decisive factors for malignant transformation in a histopathological subtype are specific. Objectives To further analyze genes found in PA and CXPA using the CGH-array technique. The genes found were analyzed using the InteractiVenn virtual tool (http://www.interactivenn.net/) and grouped into a Microsoft Excel worksheet. Results: Of the 460 genes amplified in the studied samples, 287 (62.4%) were related only to CXPA, whereas 144 (31.3%) were related to residual PA. Twenty-nine (6.3%) of these genes were common between residual PA and CXPA. Regarding the degree of invasion of CXPA, there was an increase in the number of genes amplified as the degree of invasion and aggression increased: 8 genes related to intracapsular CXPA, 65 to minimally invasive CXPA, and 373 to weakly invasive. Moreover, when comparing residual AP and intracapsular CXPA, two genes were common to these groups: ERRB2 and GRB7. As for the histological subtype, the high-grade samples had more amplifications (320 amplified genes) than the low-grade ones (129 genes). Three of these genes were common among residual PAs and CXPA: HMGA2, RPSAP52, and LOC100129940. As for the replicates, MYNC, ERBB2, BRIP1, and HMGA2 were the most repeated amplified genes in the residual PAs. HMGA2, ERRBB2, CDK12, RPSAP52, LOC100129940, and LOC100507250 were the genes with the most replicates in CXPA. Conclusion HMGA2, ERRB2, and RPSAP52 may play a key role in PA carcinogenesis, whereas GRB7, CDK12, MYNC, and BRIP1 appear to act as coadjutants.


2010 ◽  
Vol 2 (1) ◽  
pp. 6
Author(s):  
Hassan Mohamed Al Bisher

Coexistence of parotid tuberculosis along with a benign parotid tumor is a rare entity with only nine cases reported in the literature. We report here a case of primary parotid tuberculosis with concurrent pleomorphic adenoma in a 51-year-old female.


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