scholarly journals Predictive Value of Neutrophil Lymphocyte Ratio and Platelet Lymphocyte Ratio in Immediate Outcomes of ST-elevation Myocardial Infarction: A Cross-sectional Study

2021 ◽  
Author(s):  
Sneha Barkur Sadashiva ◽  
KS Chenthil
Keyword(s):  
Myocardial Infarction ◽  
Risk Score ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
St Elevation ◽  
Timi Risk Score

Introduction: There have been various inflammatory markers implicated in the pathogenesis of Acute Coronary Syndromes (ACS). However, the role of the Neutrophil Lymphocyte Ratio (NLR) and Platelet Lymphocyte Ratio (PLR) as prognostic markers in ST-elevation Myocardial Infarction (STEMI) remains poorly researched. Aim: To determine the prognostic value of NLR and PLR to predict the immediate outcomes in patients with acute STEMI, and if any association exists between NLR/PLR and Thrombolysis in Myocardial Infarction (TIMI) risk score. Materials and Methods: This was a cross-sectional study conducted at a tertiary care centre, Puducherry, India, where 190 patients who presented to casualty with STEMI were enrolled. The patient co-morbidities, personal and family history were obtained. The routine laboratory parameters including platelets, lymphocytes, neutrophils and their corresponding ratios were calculated. Patients were grouped into low and high NLR/PLR groups and were assessed for occurrence of in-hospital mortality or Major Adverse Cardiovascular Events (MACE). Analysis was made to see if there is an association between NLR/PLR and MACE. Chi-square test and one-way ANOVA test was used for statistical significance. Results: Among 190 subjects, 157 male and 33 female with mean age of 55.72±11.24 years were included. A total of 8.94% patients 8.94% had MACE. NLR was positively associated with MACE (p-value=0.0006), whereas PLR was not associated with MACE. Patients with high NLR had 1.45 times higher odds of having MACE. NLR was significantly associated with TIMI risk score. Both NLR (F ratio=6.341) and PLR (F ratio=4.600) showed significant association with Killip classification, however NLR showed higher association (p-value <0.001). Conclusion: NLR can be used as a powerful prognostic marker for predicting immediate MACE and death in STEMI patients. In addition, NLR showed positive correlation with Killip classification and TIMI risk score.

scholarly journals IN-HOSPITAL EARLY COMPLICATIONS IN DIABETICS VS NON DIABETICS WITH ACUTE ST ELEVATION MYOCARDIAL INFARCTION AGE GROUP 30-70 YEARS

2021 ◽  
Vol 70 (Suppl-4) ◽  
pp. S576-80
Author(s):  
Gul Khan ◽  
Imtiaz Ahmed Khan ◽  
Fahad Ahmad Khan ◽  
Shaheer Farhan ◽  
Javeria Kamran ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Armed Forces ◽  
Cross Sectional Study ◽  
Diabetic Group ◽  
Diabetic Patients ◽  
Age Group ◽  
Sectional Study ◽  
Early Complications ◽  
Cross Sectional ◽  
St Elevation

Objective: To determine in hospital early complications in diabetics’ vs non diabetics with acute ST elevation myocardial infarction. Study Design: Comparative cross-sectional study. Place and Duration of Study: The study was conducted in emergency departments and adult cardiology wards of Armed Forces Institute of Cardiology/National Institute of Heart Diseases, from Aug to Nov 2019. Methodology: A comparative cross sectional study was conducted on 380 patients (190 patients with diabetes and 190 patients without diabetes) who presented with acute ST-Elevation MI in age group 30 to 70 years to emergency department of Armed Forces Institute of Cardiology/National Institute of Heart Disease during specified period. Patients with rescue PCI and new onset of LBBB were also included. Patients with age group lesser than 30 years or greater than 70 years with STEMI were excluded. Sampled with consecutive non probability technique in patients was assessed with ECG, cardiac enzymes, transthoracic echocardiography, renal Doppler and RFTs. All patients were admitted in wards and were followed up during hospital stay. Patients were evaluated and their record of Primary PCI and thrombolysis was also noted. Data was entered and analyzed with SPSS-23. Results: A total of 380 patients with STEMI were included in this study consisting of 292 (76.8%) male and 88 (23.1%) female from 30 to 70 years. The patients were divided in two groups i.e. diabetic and non-diabetic, 190 patients were included in each group. It was found that frequency of ST-Elevation MI was higher in diabetic group as compared to non-diabetic group. All the patients were analyzed for complications occurred after STElevation MI. LV failure, Brady arrhythmias, atrial fibrillation, post MI angina and cardiogenic shock were the main complications noted. It was found that all these complications are more in diabetic group post MI angina which occurred most frequently in non-diabetic group. Conclusion: In our study we observed that left ventricular failure and arrhythmias were the major complications. Mortality was higher in diabetic patients than non-diabetic patients. In both groups PPCI and SK reduced mortality. Post MI angina were found more frequent in non-diabetic group.

scholarly journals Evaluation of Door To Needle Time For Fibrinolytic Therapy of ST Elevation Myocardial Infarction (STEMI) Management In Emergency And Traumatology Department (ETD), Hospital Sultan Haji Ahmad Shah (HOSHAS), Temerloh, Pahang. Malaysia.

2017 ◽  
Vol 16 (3) ◽  
pp. 407-412
Author(s):  
Wadiah Mustafar ◽  
Sazwan Reezal Shamsuddin ◽  
Amelia Amir
Keyword(s):  
Myocardial Infarction ◽  
Medical Science ◽  
Time Frame ◽  
Cross Sectional Study ◽  
Fibrinolytic Therapy ◽  
Time Dependent ◽  
Sectional Study ◽  
Cross Sectional ◽  
Good Outcome ◽  
St Elevation

Introduction: Acute myocardial infarction is known with high mortality. The benefits of fibrinolytic administration in STEMI are time dependent. The purpose of this study is to evaluate the door-to-needle time for fibrinolytic therapy in STEMI patients.Methods: A cross sectional study of all patients who had STEMI was carried out to evaluate the management of STEMI. The duration from door-to-ECG time, door-to-needle time and the factors that contribute to the time frame in receiving treatment was reviewed. The outcomes and complications from fibrinolytic therapy were documented as well. The outcomes of the delayed in administering the treatment were also analyzed in the study.Result: Out of 19 patients received fibrinolytics within 30 minutes, 16 patients (84.2%) had good outcome. In 17 patients received fibrinolytics between 30 minutes to 1 hour, 6 patients (35.2%) had good outcome. In 15 patients received fibrinolytics more than 1 hour, 8 patients (53.3%) had good outcome.Conclusion: This study showed that a shorter door-to-needle time results in better outcome.Bangladesh Journal of Medical Science Vol.16(3) 2017 p.407-412

scholarly journals Erratum for Manuscript “Study On Neutrophil Lymphocyte Ratio And Platelet Lymphocyte Ratio In COVID-19 From Our Prospective. A Cross Sectional Study

2021 ◽  
Vol 9 (1) ◽  
pp. 87-87
Keyword(s):  
Assistant Professor ◽  
Cross Sectional Study ◽  
Associate Professor ◽  
Sectional Study ◽  
Medical Sciences ◽  
Cross Sectional ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Platelet Lymphocyte Ratio ◽  
Correct Sequence

n the article entitled “Study on Neutrophil Lymphocyte ratio and Platelet lymphocyte ratio in COVID-19 from our prospective -A cross sectional study” published in the Volume 8, Issue 3, September- December 2020 issue of the Perspectives In Medical Research ,[1] the author’s sequence and affiliation is incorrectly written. The correct sequence is as under. 1. Syed Imran Ali, Assistant Professor, Department of Physiology, Mamata Academy of Medical Sciences 2. Farha Tarannum, Assistant Professor, Department of Community medicine, Mamata Academy of Medical Sciences 3. Rubiya Khan, Assistant Professor, Department of Pathology, Mamata Academy of Medical Sciences 4. M Kanya Kumari, Professor, Department of Pathology, Mamata Academy of Medical Sciences 5. Mujahid Mohammed, Associate Professor, Department of Physiology, Mamata Academy of Medical Sciences 6. Mohammed Asghar Ali, Professor, Department of Physiology, Mamata Academy of Medical Sciences Corresponding author: Syed Imran Ali, Assistant Professor, Department of Physiology, Mamata Academy of Medical Sciences

scholarly journals Is neutrophil lymphocyte ratio a prognostic marker of acute ST elevation myocardial infarction?

2021 ◽  
Vol 8 (5) ◽  
pp. 728
Author(s):  
Sneha Barkur Sadashiva ◽  
Chenthil K. S.
Keyword(s):  
Myocardial Infarction ◽  
St Elevation Myocardial Infarction ◽  
Cardiac Events ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Pubmed Database ◽  
Coronary Syndromes ◽  
St Elevation ◽  
Prognostic Importance ◽  
Timi Risk Score

Several inflammatory biomarkers have been implicated in the pathogenesis of acute coronary syndromes. The present study aims to determine the prognostic value of neutrophil lymphocyte ratio (NLR) to predict the immediate outcomes in patients with acute ST elevation myocardial infarction and if any correlation exists between NLR and TIMI risk score. A review of articles published in Pubmed database on the prognostic importance of neutrophil lymphocyte ratio in determining major adverse cardiac events (MACE) such as arrhythmias, cardiogenic shock and in hospital mortality was done. NLR was found to be a reliable prognostic tool to assess the immediate outcome in ST elevation myocardial infarction (STEMI) patients.

scholarly journals Frequency of fragmented QRS in patients with acute Non ST elevation Myocardial Infarction (NSTEMI).

2021 ◽  
Vol 28 (01) ◽  
pp. 60-65
Author(s):  
Muhammad Yasir ◽  
Muhammad Usman ◽  
Munir Ahmed ◽  
Rehan Riaz ◽  
M Hamid Saeed
Keyword(s):  
Myocardial Infarction ◽  
Troponin I ◽  
Operational Definition ◽  
Cross Sectional Study ◽  
St Elevation Myocardial Infarction ◽  
P Value ◽  
Qrs Complex ◽  
Cross Sectional ◽  
Fragmented Qrs ◽  
St Elevation

Objective: To determine the frequency of fragmented QRS complex in patients with acute non-ST elevation myocardial infarction (NSTEMI). Study Design: Cross-Sectional Study. Setting: Department of Cardiology, Faisalabad Institute of Cardiology, Faisalabad. Period: July 15, 2019 to January 15, 2020. Material & Methods: One hundred and forty five diagnosed patients of NSTEMI on the basis of chest pain and positive troponin-I were included in this study. The electrocardiography (ECG) was performed to document the presence or absence of f QRS complex in these patients. A 12-lead ECG with paper speed of 25 or 50 mm per second and a voltage of 10 mm/mv was used. FQRS was labeled (as per operational definition). The collected data were entered and analyzed statistically by using SPSS v25.0. Data were stratified for age, gender, diabetes, smoking and hypertension. Post-stratification, f QRS complex was compared by Chi-Square test in stratified groups. A p-value ≤0.05 was taken as significant. Results: Total 145 patients presenting with NSTEMI were selected for this study. Mean age of the patients was 48.2±12.3 year. Among these patients, 90(62.1%) were males, while 55(37.9%) were females. Overall frequency of fQRS complex in patients with NSTEMI was 64(44.1%). Conclusion: There is an association of fQRS among patients with acute non-ST elevation myocardial infarction (NSTEMI). Further prospective studies are needed to determine the clinical significance of fQRS complex and identify its correlation with the incidence of possible complications.

scholarly journals Complications Associated to High TIMI Score in Patients with Acute ST Elevation Myocardial Infarction

2021 ◽  
Vol 15 (5) ◽  
pp. 1526-1528
Author(s):  
M. U. Rehman ◽  
F. Faisal ◽  
A. Abrar ◽  
A. A. Shah ◽  
M. Shoaib ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Hospital Stay ◽  
Risk Score ◽  
St Elevation Myocardial Infarction ◽  
Cross Sectional ◽  
Timi Score ◽  
Detailed Medical History ◽  
St Elevation ◽  
Timi Risk Score

Objective: To determine the complications associated to High TIMI risk score among patients presented with acute ST elevation myocardial infarction. Study Design: Cross sectional Place & Duration: Study was conducted at Cardiac Centre of Pakistan Institute of Medical Sciences (PIMS), Islamabadfor duration of 6 months from January to June, 2020. Methods: Total 290 patients of both genders with ages 35 to 80 years presented with acute myocardial infarction were included in this study. Patients detailed medical history including age, sex and residence were recorded. Thrombolysis in Myocardial Infarction (TIMI) risk score was calculated for each patient. Follow up was taken during the hospital stay and after discharge. Complications were recorded on follow-up. Data was analyzed by SPSS 21.0. Results: From all the patients high TIMI score was found in 34.48% patients. Out of 100 patients 70% were male and 30% were females with mean age 54.25+12.65 years. According to the high TIMI score 100 (34.48%) patients had score above 8 and 190 (65.52%) had score less than 8. Complications were recorded ad Ventricular fibrillation, VT, AF, Heart block, cardiogenic shock and pulmonary edema in 17%, 13%, 2%, 7%, 24% and 24% patients respectively.15% patients were died during hospital stay. 28% patients had post infarct angina, 9% patients had stroke and 28% patients treated revascularization. Conclusion: We concluded from this study that frequency of high TIMI score is high in our setting and we patients with increase score had high risk of complications and mortality. Keywords: High Thrombolysis in Myocardial Infarction, Acute ST Elevation Myocardial Infarction, Frequency, Complications, Mortality.

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