scholarly journals C-Reactive Protein as an Inflammatory Biomarker for the Assessment of Malaria Parasitemia in a Tertiary Health Care Facility in Rivers State, Nigeria

2019 ◽  
pp. 1-8
Author(s):  
Dada A. Emmanuel ◽  
Eze N. Chinwe ◽  
Akawa B. Ayodeji
Keyword(s):  
Falciparum Malaria ◽  
Teaching Hospital ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Malaria Parasitemia ◽  
Port Harcourt ◽  
Test Kit ◽  
The University ◽  
Rivers State ◽  
Serum Crp

Aim: To use C-Reactive Protein (CRP) in assessing` malaria and malaria parasitemia among out-patients in the University of Port Harcourt Teaching Hospital (UPTH). Study Design: Cross-sectional descriptive study. Place and Duration of Study: This study was carried out at the Out Patients Department (OPD) of the University of Port Harcourt Teaching Hospital, Port Harcourt, Rivers State, Nigeria. It was conducted between November 2017 and April 2018. Methodology: This study was done on 400 subjects between the ages of 11 and 60 years which consisted of 254 falciparum malaria infected patients and 164 non-infected patients. Quantitative analysis of Serum CRP was done using the High Sensitivity C-Reactive Protein (HsCRP) enzyme immunoassay test kit (Biocheck©) while malaria diagnosis was done using microscopy Giemsa thick and thin film prepared on separate slides, slides were observed under the ×10 and ×100 objectives of the light microscope. Slides viewed under a high power field with parasite density less than three (<3), between 3 and 10 (3-10), from eleven to nineteen (11-19) and greater or equal to 20 (≥20) were classified as scanty, one plus (+), two pluses (++) and three pluses (+++) respectively. Data analysis was done using statistical packages for social science (SPSS) version 21. Results: The results showed a significant (p<0.001) overall mean high serum CRP concentration (25.63±14.40 mg/l) in the malaria infected patients compared to 3.74±1.02 mg/l in the non-infected group, with a direct increment of the CRP level from the scanty to the three pluses with 9.50±0.37 mg/l, 13.51±1.6 mg/l, 44.19±2.62 mg/l and 53.84±1.75 mg/l recorded for scanty, one plus, two pluses and three pluses respectively. CRP correlated positively and significantly with malaria parasitemia (r = 0.89; p < 0.001). Conclusion: The abnormally elevated level of CRP in the infected patients showed that CRP is a positive biomarker for Plasmodium falciparum malaria and can be used as an indicator of the disease coupled with other febrile symptoms.

scholarly journals Personality Traits As Predictors Of Burnout Syndrome Among Nurses In The University Of Port Harcourt Teaching Hospital Rivers State

2020 ◽  
Vol 7 (3) ◽  
pp. 35-42
Author(s):  
R. O. Ekechukwu ◽  
Osuagwu Isabella
Keyword(s):  
Personality Traits ◽  
Teaching Hospital ◽  
Sampling Technique ◽  
Simple Random Sampling ◽  
Openness To Experience ◽  
Burnout Syndrome ◽  
Daily Work ◽  
Port Harcourt ◽  
The University ◽  
Rivers State

The study investigated personality traits as predictors of burnout syndrome among nurses in the University of Port Harcourt Teaching Hospital Rivers State. The study used the correlational research design. The population of the study comprised of all 750 nurses in the University of Port Harcourt Teaching Hospital. A sample of 300 nurses from Paediatrics Ward, Male Ward, Female Ward and Intensive Care Unit (ICU), were randomly selected using the simple random sampling technique (balloting). Two instruments titled; Maslach Burnout Scale (MBS) by Maslach (1996) and Personality Inventory (NEO) by Costa and McCrae (1992) were used to collect data for the study. The Cronbach Alpha reliability was used to establish the internal consistency reliability coefficients of 0.87 and 0.81respectively. Responses to the research questions were analyzed with mean and standard deviation, while the hypotheses will be tested with multiple regression associated with independent sample t-test statistics. The findings of the study revealed that personality traits (neuroticism, extraversion, openness to experience) jointly predict burnout syndrome among nurses in University of Port Harcourt Teaching Hospital. Further analysis of the result showed that when personality traits of neuroticism, extraversion, openness to experience where looked at independently, only neuroticism and extraversion relate significantly predict burnout syndrome while openness to experience did not. Based on the findings of the study it was recommended among others that counsellors, psychologists and others in the helping profession should readily offer practical assistance to nurses experiencing burnout to enable them cope with the stressful experience they encounter in their daily work assignments.

Stroke at the University of Port Harcourt Teaching Hospital, Rivers State, Nigeria

2009 ◽  
Vol 39 (3) ◽  
pp. 150-152 ◽  
Author(s):  
Arthur Onwuchewa ◽  
Hope BellGam ◽  
God'spower Asekomeh
Keyword(s):  
Teaching Hospital ◽  
Port Harcourt ◽  
The University ◽  
Rivers State

scholarly journals Antibiotic Susceptibility of High Vaginal Swab’s Isolates Obtained from the University of Port Harcourt Teaching Hospital, Rivers State, Nigeria

2019 ◽  
pp. 1-10
Author(s):  
E. Effiong ◽  
N. N. Ndukwe ◽  
Y. S. Wali
Keyword(s):  
Teaching Hospital ◽  
Adaptive Strategy ◽  
Vaginal Swab ◽  
Herbal Remedies ◽  
Diffusion Method ◽  
Self Medication ◽  
Port Harcourt ◽  
Antibiotics Susceptibility ◽  
The University ◽  
Rivers State

Introduction: Bacterial vaginosis is caused by the invasion of the vagina by pathogenic microbiota with a unique adaptive strategy. Immunodeficiency and immune compromised female patients may have reported cases of this category of infections. Aims: This study evaluated the susceptibility pattern of High vaginal swab (HVS) isolates using both Optudisc and Abtek antibiotics susceptibility disc obtained from the Department of Medical Microbiology and Parasitology Unit, University of Port Harcourt Teaching Hospital (UPTH); Rivers State, South-South Nigeria. Study Design: Thirty (30) isolates with multidrug resistance were screened, selected and identified with frequencies of occurrence with 36.67% E. coli, 29.9% Klebsiella sp., 16.67% Staphylococcus aureus, 6.6% Pseudomonas sp. and 13.33% Proteus sp. The susceptibility of the isolates was assessed using Kirby Bauer disc diffusion method. Results: Over 80% were susceptible to Gentamicin, 64% to Ofloxacin, using the Abtex Biological Limited while Optudisc revealed 72% to Peflacin, Ciprofloxacin, Streptomycin, 60% resistant to Ampicillin, 56% to Nalidixic Acid, Septrin. About 100% sensitivity was observed in the second generation Cephalosporins, Cefuroxime and Ceftazidime, whereas 75% were resistant to Oxacillin and Augmentin. While Optudisc for Gram-positive isolates were 100% susceptible to Levofloxacin and Ciprofloxacin. Statistical analysis using t-test at p< 0.05 showed that mean results using the different disc were significant. Conclusion: The trend in the susceptibility of isolates was attributed to the spate of self-medication and abuse and misuse of herbal remedies. These findings underscore the need to enforce proper susceptibility testing prior to administration of therapeutic formulations.

scholarly journals Prevalence of systemic lupus erythematosus amongst child-bearing female patients attending University of Port Harcourt Teaching Hospital, Port Harcourt, Rivers State, Nigeria

2021 ◽  
Vol 14 (3) ◽  
pp. 090-097
Author(s):  
Asuzu-Samuel Henrrietta Ogadimma ◽  
Oluwatayo, Beatrice Olatundun
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Teaching Hospital ◽  
Lupus Erythematosus ◽  
Antinuclear Antibody ◽  
Systemic Lupus ◽  
Female Patients ◽  
Port Harcourt ◽  
Child Bearing ◽  
The University ◽  
Rivers State

Systemic lupus erythematosus (SLE), a chronic and progressive multisystem autoimmune disorder is chiefly mediated by immune complexes in which the body’s immune system produce antibody (mostly antinuclear antibody) against normal cells and organs leading to inflammatory injuries. Several studies on this disease have been done in different parts of the world but very little exist in Nigeria, particularly in Port Harcourt. The study aim to determine the prevalence of systemic lupus erythematosus in Child-bearing female patients between the age ranges of 15 – 45 years, attending University of Port Harcourt Teaching Hospital, Rivers State, Nigeria. Ethical approval was sought for and obtained from the Ethical committee of the University of Port Harcourt Teaching Hospital. A total sample size of 207 was used. 5ml of blood samples were collected with 5ml syringe and needle into non-heparinized bottle from the antecubital fossa of recruited study group between 8am and 11am each day and was taken to the laboratory for analysis. De-fibrination method was used with the aid of centrifuge and microscope for detection of LE cell. Using an SLE latex reagent, the serum was analyzed for the presence of antinuclear antibody after centrifuging for 10mins. The SLE test kit used contained positive and negative controls to which the results were compared. Results gotten were all negative for the test group. This indicates a zero (0) prevalence level of systemic lupus erythematosus amongst child-bearing female patients attending the University of Port Harcourt Teaching Hospital.

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