scholarly journals Antibiotic Susceptibility of High Vaginal Swab’s Isolates Obtained from the University of Port Harcourt Teaching Hospital, Rivers State, Nigeria

2019 ◽  
pp. 1-10
Author(s):  
E. Effiong ◽  
N. N. Ndukwe ◽  
Y. S. Wali
Keyword(s):  
Teaching Hospital ◽  
Adaptive Strategy ◽  
Vaginal Swab ◽  
Herbal Remedies ◽  
Diffusion Method ◽  
Self Medication ◽  
Port Harcourt ◽  
Antibiotics Susceptibility ◽  
The University ◽  
Rivers State

Introduction: Bacterial vaginosis is caused by the invasion of the vagina by pathogenic microbiota with a unique adaptive strategy. Immunodeficiency and immune compromised female patients may have reported cases of this category of infections. Aims: This study evaluated the susceptibility pattern of High vaginal swab (HVS) isolates using both Optudisc and Abtek antibiotics susceptibility disc obtained from the Department of Medical Microbiology and Parasitology Unit, University of Port Harcourt Teaching Hospital (UPTH); Rivers State, South-South Nigeria. Study Design: Thirty (30) isolates with multidrug resistance were screened, selected and identified with frequencies of occurrence with 36.67% E. coli, 29.9% Klebsiella sp., 16.67% Staphylococcus aureus, 6.6% Pseudomonas sp. and 13.33% Proteus sp. The susceptibility of the isolates was assessed using Kirby Bauer disc diffusion method. Results: Over 80% were susceptible to Gentamicin, 64% to Ofloxacin, using the Abtex Biological Limited while Optudisc revealed 72% to Peflacin, Ciprofloxacin, Streptomycin, 60% resistant to Ampicillin, 56% to Nalidixic Acid, Septrin. About 100% sensitivity was observed in the second generation Cephalosporins, Cefuroxime and Ceftazidime, whereas 75% were resistant to Oxacillin and Augmentin. While Optudisc for Gram-positive isolates were 100% susceptible to Levofloxacin and Ciprofloxacin. Statistical analysis using t-test at p< 0.05 showed that mean results using the different disc were significant. Conclusion: The trend in the susceptibility of isolates was attributed to the spate of self-medication and abuse and misuse of herbal remedies. These findings underscore the need to enforce proper susceptibility testing prior to administration of therapeutic formulations.

scholarly journals C-Reactive Protein as an Inflammatory Biomarker for the Assessment of Malaria Parasitemia in a Tertiary Health Care Facility in Rivers State, Nigeria

2019 ◽  
pp. 1-8
Author(s):  
Dada A. Emmanuel ◽  
Eze N. Chinwe ◽  
Akawa B. Ayodeji
Keyword(s):  
Falciparum Malaria ◽  
Teaching Hospital ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Malaria Parasitemia ◽  
Port Harcourt ◽  
Test Kit ◽  
The University ◽  
Rivers State ◽  
Serum Crp

Aim: To use C-Reactive Protein (CRP) in assessing` malaria and malaria parasitemia among out-patients in the University of Port Harcourt Teaching Hospital (UPTH). Study Design: Cross-sectional descriptive study. Place and Duration of Study: This study was carried out at the Out Patients Department (OPD) of the University of Port Harcourt Teaching Hospital, Port Harcourt, Rivers State, Nigeria. It was conducted between November 2017 and April 2018. Methodology: This study was done on 400 subjects between the ages of 11 and 60 years which consisted of 254 falciparum malaria infected patients and 164 non-infected patients. Quantitative analysis of Serum CRP was done using the High Sensitivity C-Reactive Protein (HsCRP) enzyme immunoassay test kit (Biocheck©) while malaria diagnosis was done using microscopy Giemsa thick and thin film prepared on separate slides, slides were observed under the ×10 and ×100 objectives of the light microscope. Slides viewed under a high power field with parasite density less than three (<3), between 3 and 10 (3-10), from eleven to nineteen (11-19) and greater or equal to 20 (≥20) were classified as scanty, one plus (+), two pluses (++) and three pluses (+++) respectively. Data analysis was done using statistical packages for social science (SPSS) version 21. Results: The results showed a significant (p<0.001) overall mean high serum CRP concentration (25.63±14.40 mg/l) in the malaria infected patients compared to 3.74±1.02 mg/l in the non-infected group, with a direct increment of the CRP level from the scanty to the three pluses with 9.50±0.37 mg/l, 13.51±1.6 mg/l, 44.19±2.62 mg/l and 53.84±1.75 mg/l recorded for scanty, one plus, two pluses and three pluses respectively. CRP correlated positively and significantly with malaria parasitemia (r = 0.89; p < 0.001). Conclusion: The abnormally elevated level of CRP in the infected patients showed that CRP is a positive biomarker for Plasmodium falciparum malaria and can be used as an indicator of the disease coupled with other febrile symptoms.

scholarly journals Biodeterioration of Classroom Wall Surfaces in the University of Port Harcourt, Nigeria

2019 ◽  
pp. 1-8
Author(s):  
B. C. Anele ◽  
P. O. Okerentugba ◽  
H. O. Stanley ◽  
C. J. Ugboma
Keyword(s):  
Physicochemical Parameters ◽  
Biochemical Characterization ◽  
Diffusion Method ◽  
Frequency Of Occurrence ◽  
Bacterial Isolates ◽  
Port Harcourt ◽  
Aspergillus Fumigates ◽  
Bacillus Spp ◽  
Antibiotics Susceptibility ◽  
The University

Aim: This study investigated the biodeterioration of classroom wall surfaces in the University of Port Harcourt, Nigeria. Study Design: Scrapings from selected classroom wall surfaces were analyzed for their microbiological and physicochemical parameters. Isolated bacteria were screened for their antibiotics susceptibility. Place and Duration of Study: This study was carried out at the University of Port Harcourt between March - June 2018. Methods: The population of culturable bacterial and fungal biodeteriogens was determined by plating. Physicochemical parameters were determined using standard methods. Antibiotic susceptibility pattern of the bacterial isolates was determined using the disc diffusion method. Results: The total culturable heterotrophic bacterial counts ranged from 6.48 to 8.23 log CFU/g while the total fungal counts ranged from 5.00 to 7.28 log CFU/g. The bacterial isolates identified by biochemical characterization and their frequency of occurrence are Micrococcus spp. (7.3%), Citrobacter spp. (3.2%), Bacillus spp. (39.1%), Serratia spp. (3.2%), Corynebacterium spp. (10.9%), Staphylococcus aureus (20.1%), Proteus spp. (9.2%) and Shigella spp (7.0%). The fungal isolates and their frequency of occurrence are Aspergillus flavus (39.1%), Penicillium spp. (20.1%), Microsporium canis (14.3%), Coccidioides spp. (10.9%), Aspergillus fumigates (3.2%) and Tricophyton spp (3.2%). All antibiotics used showed activity against all bacterial isolates except Proteus spp. From the results of the physicochemical parameters, pH values ranged from 6.15 to 9.01, nitrate ranged from 5.30 to 14.83 mg/kg, phosphate ranged 2.19 to 5.94 mg/kg, sulphate ranged from 12.97 to 19.07 mg/kg and Total Organic Carbon ranged from 74.89 to 119.43 mg/kg. Conclusions: This study has shown the potential public health risk associated with classroom building deterioration owing to the presence of pathogenic microorganisms. Therefore, measures towards prevention and mitigation of classroom building biodeterioration should be in place.

scholarly journals Personality Traits As Predictors Of Burnout Syndrome Among Nurses In The University Of Port Harcourt Teaching Hospital Rivers State

2020 ◽  
Vol 7 (3) ◽  
pp. 35-42
Author(s):  
R. O. Ekechukwu ◽  
Osuagwu Isabella
Keyword(s):  
Personality Traits ◽  
Teaching Hospital ◽  
Sampling Technique ◽  
Simple Random Sampling ◽  
Openness To Experience ◽  
Burnout Syndrome ◽  
Daily Work ◽  
Port Harcourt ◽  
The University ◽  
Rivers State

The study investigated personality traits as predictors of burnout syndrome among nurses in the University of Port Harcourt Teaching Hospital Rivers State. The study used the correlational research design. The population of the study comprised of all 750 nurses in the University of Port Harcourt Teaching Hospital. A sample of 300 nurses from Paediatrics Ward, Male Ward, Female Ward and Intensive Care Unit (ICU), were randomly selected using the simple random sampling technique (balloting). Two instruments titled; Maslach Burnout Scale (MBS) by Maslach (1996) and Personality Inventory (NEO) by Costa and McCrae (1992) were used to collect data for the study. The Cronbach Alpha reliability was used to establish the internal consistency reliability coefficients of 0.87 and 0.81respectively. Responses to the research questions were analyzed with mean and standard deviation, while the hypotheses will be tested with multiple regression associated with independent sample t-test statistics. The findings of the study revealed that personality traits (neuroticism, extraversion, openness to experience) jointly predict burnout syndrome among nurses in University of Port Harcourt Teaching Hospital. Further analysis of the result showed that when personality traits of neuroticism, extraversion, openness to experience where looked at independently, only neuroticism and extraversion relate significantly predict burnout syndrome while openness to experience did not. Based on the findings of the study it was recommended among others that counsellors, psychologists and others in the helping profession should readily offer practical assistance to nurses experiencing burnout to enable them cope with the stressful experience they encounter in their daily work assignments.

Stroke at the University of Port Harcourt Teaching Hospital, Rivers State, Nigeria

2009 ◽  
Vol 39 (3) ◽  
pp. 150-152 ◽  
Author(s):  
Arthur Onwuchewa ◽  
Hope BellGam ◽  
God'spower Asekomeh
Keyword(s):  
Teaching Hospital ◽  
Port Harcourt ◽  
The University ◽  
Rivers State

scholarly journals Antibiogram of Biofilm Producing Bacteria Isolated from Urine of Patients in Three Hospitals in Port Harcourt, Rivers State

2021 ◽  
pp. 5-20
Author(s):  
Onyedibia Golden Chukwuma ◽  
Williams Janet Olufunmilayo ◽  
Douglas Salome Ibietela
Keyword(s):  
Teaching Hospital ◽  
Bacterial Biofilm ◽  
Urine Samples ◽  
Diffusion Method ◽  
Sensitivity Testing ◽  
Resistance To Antibiotics ◽  
Port Harcourt ◽  
Biofilm Bacteria ◽  
Tract Infections ◽  
Rivers State

Aim: The aim of this study was to determine the antibiogram of biofilm producing bacteria isolated from urine of patients in three hospitals in Port Harcourt, Rivers State. Study Design: The study employs statistical analysis of the data and interpretation Place and Duration of Study: The study was conducted at three (3) hospitals; University of Port Harcourt Teaching Hospital (UPTH), Meridian Hospital D / line branch (MRD1) and Meridian Hospital Ikoku branch, all located in Port Harcourt, Rivers State. Sample collection was for three (3) months, analysis was carried out daily and it lasted for six (6) months. Methodology: A total of Forty-five (45) urine samples were collected for a period of three (3) months from the three (3) hospitals. The samples were labelled properly, according to date and time of collection. The collected samples were subjected to standard microbiological procedures which includes standard plate counts, identification, biofilm screening, sensitivity testing using Kirby-Bauer disk diffusion method, Phenotypic screening of extended spectrum beta lactamase and molecular characterization of the isolates Results: The results of the bacterial population of urine samples from the hospitals showed that the total heterotrophic bacterial counts for Meridian Hospital D/line (MRD1), Meridian Hospital Ikoku (MRD2) and University of Port Harcourt Teaching Hospital (UPTH) ranged from 4.93 - 6.30 x107cfu/ml. The Total coliform count ranged from 1.89-3.04 x106cfu/ml for Meridian Hospital D/line (MRD1), Meridian Hospital Ikoku (MRD2) and University of Port Harcourt Teaching Hospital (UPTH). Total faecal coliform counts ranged from 0.78-1.11 x105CFU/ml for Meridian Hospital D/line (MRD1), Meridian Hospital Ikoku (MRD2) and University of Port Harcourt Teaching Hospital (UPTH). A total of fifty-eight (58) bacterial isolates were isolated from urine of patients and 36(62.1%) isolates were identified as biofilm producers. The biofilm bacteria identified were 17.2% Staphylococcus,6.9% E. coli, 10.3% Pseudomonas, 6.9% Proteus ,10.3% Bacillus and 10.3% Enterococcus species. Biofilm forming ability of bacteria is considered a virulent factor and it is implicated to being a possible cause of increased resistance to most antibiotics. Varying susceptibility pattern was observed among biofilm isolates. Biofilm bacteria were resistant to several groups of antibiotics. Ofloxacin, Gentamycin, Imipenem and Nitrofurantoin can be used as drug of interest for most bacterial biofilm urinary tract infections. CTX-M and TET A gene were identified in the biofilm bacteria in this study to be possible factors that confer resistance to antibiotics. The presence of icaD and papC gene in the isolates whose genome were studied have been found to be possible factors that confers biofilm producing ability. This study indicates the emergence and rapid spread of biofilm producing bacteria and their resistance to antibiotics. Therefore, strict infection control practices as well as therapeutic guidance for confirmed infections should be rapidly initiated.

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