scholarly journals Comparative Study of Clinico-Pathological Profiles of Patients with Proximal Versus Distal Gastric Adenocarcinoma

2020 ◽  
pp. 107-113
Author(s):  
Ashwini Krishnamoorthy ◽  
Shreya Rajkumar ◽  
K. Kuberan
Keyword(s):  
Gastric Adenocarcinoma ◽  
Gastrointestinal Endoscopy ◽  
Histopathological Examination ◽  
Clinical Pathology ◽  
Western Hemisphere ◽  
Upper Gastrointestinal Endoscopy ◽  
Medical College ◽  
Gastric Adenocarcinomas ◽  
Stomach Adenocarcinoma ◽  
Upper Gastrointestinal

Background: Stomach adenocarcinoma has been a major source of malignant development through the greater part of the 20th century. In different parts of the world, the prevalence of this disease has decreased, mostly due to changes in diet and some other natural constituents. Aim: To examine the clinical pathology of patients with proximal and distal gastric adenocarcinomas. Methodology: This was the prospective work carried out with gastric adenocarcinoma patients treated at Sree Balaji Medical College and Hospital (SBMCH), Chennai, Tamilnadu, India. All patients were undergone upper gastrointestinal endoscopy and an imaging. In endoscopy, biopsies will be taken from the lesion and biopsies were subjected to histopathological examination. Results: The most striking epidemiologic perceptions were the increasing frequency of adenocarcinomas of the proximal stomach and distal throat. We found that the occurrence of proximal gastric adenocarcinomas isn't expanding in our populace when contrasted with the rising rate of such proximal tumors in the Western Hemisphere. Conclusion: In our investigation distal gastric adenocarcinomas were a more incessant finding than the proximal gastric adenocarcinomas.

scholarly journals Upper Gastrointestinal Endoscopy in Lumbini Medical College and Teaching Hospital

2013 ◽  
Vol 1 (1) ◽  
pp. 7
Author(s):  
Bishal Khattri Chhetri ◽  
M S Paudel ◽  
Nabin Pokharel ◽  
Shadev Prasad Dhungana ◽  
Anuj Paudel ◽  
...  
Keyword(s):  
Duodenal Ulcer ◽  
Gastrointestinal Tract ◽  
Teaching Hospital ◽  
Esophageal Varices ◽  
Gastrointestinal Endoscopy ◽  
Common Finding ◽  
Upper Gastrointestinal Endoscopy ◽  
Ulcer Disease ◽  
Medical College ◽  
Upper Gastrointestinal

  Introduction: Upper gastrointestinal (UGI) endoscopy includes visualization of the oropharynx, esophagus, stomach, and proximal duodenum, with real time assessment and interpretation of the findings encountered. An upper endoscopy is indicated in the diagnostic evaluation of signs and symptoms of a wide variety of gastrointestinal disorders. Besides there are some therapeutic implication of the endoscopy. This study was conducted to study the spectrum of diseases found during the upper gastrointestinal endoscopy in patient presenting in Lumbini Medical College and Teaching Hospital (LMCTH).   Methods: This was a retrospective observational study carried out in LMCTH. The endoscopic record book of the patients who underwent UGI endoscopy for various reasons from February 2011 to 2013 was analysed. The risk factor of smoking and alcohol was also included and analysed in the study.   Results: All together 550 upper GI endoscopy was performed in the two years. There were 290 males (52.72%) and females were 260 (47.38%). The mean age was 45.7 years (SD=17.9). Most of the patient belonged to the age group 41 to 80 years (71%). Among total patients, 209 (38%) of them were found to be macroscopically normal. Of those who had positive endoscopic findings; 165 (48.4%) had gastritis and 36 (10.6%) had duodenal ulcer, esophageal varices was in 30 (8.8%), gastric carcinoma in nine (2.6%) of cases. Cigarette smoking was significantly associated with the presence of peptic ulcer disease (p=0.01) and malignancy of gastrointestinal tract (p=0.03). Alcohol intake was non-significantly related to peptic ulceration (p=0.07) and malignancy of gastrointestinal tract (p=0.09).   Conclusion: Upper gastrointestinal endoscopy is a safe and useful procedure for investigating patients with gastrointestinal complains. Gastritis was the most common finding among the patients who had abnormal endoscopy followed by duodenal ulcer and esophageal varices.

scholarly journals Is It Necessary to Perform Pre Operative Upper Gastrointestinal Endoscopy in Elective Symptomatic Cholelithasis?

2021 ◽  
pp. 13-17
Author(s):  
Ubedullah Shaikh ◽  
Zahid Ali Memon ◽  
Masroor Mubeen Phulpoto ◽  
Munawar Hussain Mangi ◽  
Nawaz Ali Dal ◽  
...  
Keyword(s):  
Prospective Observational Study ◽  
Gastrointestinal Endoscopy ◽  
Gallstone Disease ◽  
Upper Gastrointestinal Endoscopy ◽  
Foetal Loss ◽  
Medical College ◽  
Atypical Symptoms ◽  
Associated Conditions ◽  
Study Population ◽  
Upper Gastrointestinal

Objective:  Is it necessary to perform pre operative upper gastrointestinal endoscopy in elective symptomatic cholelithasis? Study Design: Prospective observational study. Place and Duration of Study: This study was conducted at surgical departments of  Services Hospital,  Ruth PFAHU, Civil Hospital Karachi, Shaheed Benazir Bhutto Medical College, Lyari Karachi and Liaquat University Of Medical and Health Sciences, Jamshoro from July 2018 to December 2019. Methodology: Study consisted of 382 patients. All patients were subjected to Upper Gastrointestinal Endoscopy 24 to 48 hours before cholecystectomy followed by biopsy were obtained for histopathology if required. Those patients not willing for surgery, General anesthesia problem, pregnant ladies due to risk of foetal loss, carcinoma of gall bladder, stone in CBD and obstructive jaundice were excluded. Results: Out of the 382 patients, 66(17.27%) males and 316(82.72%) females with mean age of study population was 46.10 ± 6.31 years (22 to 65 years). Patients were present typical pain in 146(38.21%) cases and atypical pain in 236(61.78%) cases. Pre operative upper gastrointestinal endoscopy findings revealed Esophagitis in 22(5.75%) cases, GERD in 26(6.80%) cases, gastritis in 88(23.03%), gastric ulcer 49(12.82%), duodenal ulcer in 39(10.20%), polps 21(5.49%) and carcinoma of stomach 9(2.35%). Out of 236(61.78%) cases with atypical pain had persistence of symptoms in 141 (59.74%) cases upto four months. Conclusion: We conclude that upper gastrointestinal endoscopy preoperatively for gallstone disease should be performed. So that preoperatively atypical symptoms are evaluate and taken care of, and patients is fully informed and also treated for associated conditions.

scholarly journals Intramural duodenal haematoma with mucosal prolapse causing intestinal obstruction

2019 ◽  
Vol 12 (4) ◽  
pp. e228276
Author(s):  
Arun Kumar Loganathan ◽  
Harshjeet Singh Bal
Keyword(s):  
Small Bowel ◽  
Intestinal Obstruction ◽  
Gastrointestinal Endoscopy ◽  
Histopathological Examination ◽  
Vascular Malformations ◽  
Duplication Cyst ◽  
Upper Gastrointestinal Endoscopy ◽  
Proximal Jejunum ◽  
Upper Gastrointestinal ◽  
Duodenal Haematoma

Intramural small bowel haematoma is a rare cause of intestinal obstruction in children. Coagulation disorders or anticoagulant therapy are the most common cause followed by blunt trauma. A one and half-year-old boy, with known case of gastro-oesophageal reflux disease had undergone upper gastrointestinal endoscopy and biopsy. Four days later, he presented to us with clinical features of small bowel obstruction. CT of the abdomen showed features suggestive of haemorrhagic duplication cyst. Explorative laparotomy revealed 15–20 cm of bowel from the third part of the duodenum to proximal jejunum filled with clotted blood and thinned out serosa. There was no evidence of intraluminal blood in the distal bowel loops. Resection of the involved bowel with primary anastomoses was done. Histopathological examination of bowel revealed intramural haematoma associated with prolapse of the mucosa. There was no evidence of duplication cyst or vascular malformations. Postoperative period was uneventful.

scholarly journals Mixed adenoneuroendocrine carcinoma of proximal stomach; a rare but sinister pathology

2020 ◽  
Vol 10 (2) ◽  
pp. 1772-1775
Author(s):  
Deepshikha Gaire ◽  
Daisy Maharjan ◽  
Nisha Sharma
Keyword(s):  
Gastrointestinal Endoscopy ◽  
Histopathological Examination ◽  
Gastroesophageal Junction ◽  
Upper Gastrointestinal Endoscopy ◽  
Radiological Findings ◽  
Proximal Stomach ◽  
History Of ◽  
Adenocarcinoma Component ◽  
Physical Findings ◽  
Upper Gastrointestinal

Mixed adeno-neuroendocrine carcinoma is a rare tumor of the gastrointestinal tract comprising of both epithelial and neuroendocrine components, each representing at least 30% of the tumor. Diagnosis is based on clinical evaluation, radiological findings, histopathological features in conjunction with immunostaining with specific neuroendocrine markers such as chromogranin, synaptophysin, CD56, and markers of epithelial differentiation such as cytokeratin, CDX2, and carcinoembryonic antigen. A 50-year-old female presented with a history of dysphagia, chest pain, anorexia, and significant weight loss with normal physical findings and baseline investigations. Upper Gastrointestinal endoscopy showed growth at the gastroesophageal junction involving cardia of the stomach. Histopathological examination of the resected mass showed both adenocarcinoma and neuroendocrine carcinomatous components each involving more than 30% of total mass examined. Identifying adenocarcinoma component admixed with a high-grade neuroendocrine component is significant as the prognosis and survival of patients differ from pure adenocarcinoma.

scholarly journals Appropriateness of Referral for Upper Gastrointestinal Endoscopy in a Tertiary Care Hospital

2020 ◽  
Vol 14 (2) ◽  
pp. 152-155
Author(s):  
Md Mizanur Rahman Khan ◽  
Md Abdul Wahab ◽  
Md Muaz Yasin ◽  
Farzana Zafreen
Keyword(s):  
Open Access ◽  
Gastrointestinal Endoscopy ◽  
Tertiary Care ◽  
Armed Forces ◽  
Upper Gastrointestinal Endoscopy ◽  
Care Hospital ◽  
College Hospital ◽  
Endoscopic Procedures ◽  
Medical College ◽  
Upper Gastrointestinal

Introduction: Upper gastrointestinal endoscopy (UGE) allows physicians to directly schedule endoscopic procedures for their patients without prior consultation. Evaluation of appropriateness of endoscopic procedures is associated with costs and benefits. Objectives: To assess the appropriateness of the use of UGE in an open-access setting in Bangladesh. Materials and Methods: This cross-sectional multicenter study was conducted among 300 patients referred for UGE at Dhaka Medical College Hospital and Shaheed Suhrawardi Medical College and Hospital from January 2016 to June 2016. The American Society for Gastrointestinal Endoscopy (ASGE) guidelines was used to assess the appropriateness of referral. The participants were selected by purposive nonprobability sampling and a pre-tested questionnaire was used for data collection. Results: Out of 300 respondents 62.3% was male. History of smoking was more in male and taking NSAIDs were more in the female. In UGE 46.7% revealed normal findings but majority 53.3% had some pathology. About 86% cases, UGE was found appropriate according to ASGE guideline and majority appropriate cases 37.3% were referred by internal medicine specialist. Appropriateness of referral among different physicians was not statistically significant. Conclusion: Appropriateness of referral for UGE performed in tertiary care level hospitals in an open-access setting like Bangladesh was satisfactory. Journal of Armed Forces Medical College Bangladesh Vol.14 (2) 2018: 152-155

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