scholarly journals Assessment of Hepatoprotective Potential of Manilkara hexandra STEM Bark: An In-vitro Analysis

2021 ◽  
pp. 19-38
Author(s):  
Prasoon Kumar Saxena ◽  
Deepak Nanda ◽  
Ritu Gupta
Keyword(s):  
Carbon Tetrachloride ◽  
Cell Line ◽  
Tree Species ◽  
Stem Bark ◽  
Western India ◽  
Thar Desert ◽  
Hepg2 Cell Line ◽  
Vitro Analysis ◽  
In Vitro Analysis

Background: Manilkara hexendra (Bignoniaceae) is tree species, privately known as Rohida, found in Thar Desert districts of northwest and western India. The bark acquired from the stem is utilized as a solution for syphilis, urinary issues, amplification of spleen, gonorrhea, leucoderma, and liver infections. The point of this work is to consider the hepatoprotective impact of unrefined Methanolic removal from the bark portions of Manikara hexendra. The methanolic extricate got from bark portions of Manikara hexendra was assessed via cell line study in HepG2 cell line followed in for hepatoprotective movement in rodents by initiating liver harm via paracetamol and carbon tetrachloride. Results: The methanolic extricate at an oral portion of 200 mg/kg displayed a critical (P < 0.05) defensive impact. These biochemical perceptions were enhanced by histopathological assessment of liver areas. The action might be a consequence of the presence of flavonoid mixes. Moreover, the intense harmfulness of the concentrates gave no indications of poisonousness up to a portion level of 2000 mg/kg. Conclusion: It could be inferred that the methanolic concentrate of Manikara hexendra has huge hepatoprotective properties.

scholarly journals In Vitro Analysis of CsA-Induced Hepatotoxicity in HepG2 Cell Line: Oxidative Stress and α2 and β1 Integrin Subunits Expression

2013 ◽  
Vol 13 (8) ◽  
Author(s):  
Zohreh Mostafavi-Pour ◽  
Fatemeh Khademi ◽  
Fatemeh Zal ◽  
Ahmad-Reza Sardarian ◽  
Fatemeh Amini
Keyword(s):  
Oxidative Stress ◽  
Cell Line ◽  
Hepg2 Cell ◽  
Β1 Integrin ◽  
Hepg2 Cell Line ◽  
Vitro Analysis ◽  
In Vitro Analysis

In-Vitro Analysis of Glucose and Quercetin Effects on m-TOR and Nrf-2 Expression in HepG2 Cell Line (Diabetes and Cancer Connection)

2018 ◽  
Vol 70 (5) ◽  
pp. 770-775 ◽  
Author(s):  
Amir Yarahmadi ◽  
Fatemeh Khademi ◽  
Zohreh Mostafavi-Pour ◽  
Fatemeh Zal
Keyword(s):  
Cell Line ◽  
Hepg2 Cell ◽  
Hepg2 Cell Line ◽  
Vitro Analysis ◽  
In Vitro Analysis

scholarly journals In Vitro Analysis of Breast Cancer Cell Line Tumourspheres and Primary Human Breast Epithelia Mammospheres Demonstrates Inter- and Intrasphere Heterogeneity

PLoS ONE ◽  
2013 ◽  
Vol 8 (6) ◽  
pp. e64388 ◽  
Author(s):  
Chanel E. Smart ◽  
Brian J. Morrison ◽  
Jodi M. Saunus ◽  
Ana Cristina Vargas ◽  
Patricia Keith ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
Human Breast ◽  
Primary Human Breast ◽  
Vitro Analysis ◽  
In Vitro Analysis

In silico and in vitro Analysis of Alkylated Salicylic Acid Inhibition Activity on Cervical HeLa Cancer Cell Line

2021 ◽  
Vol 21 (2) ◽  
pp. 59-69
Author(s):  
Priscilla Ardianto ◽  
Ade Arsianti ◽  
Khaerunissa Anbar Isti ◽  
Fadilah Fadilah
Keyword(s):  
Salicylic Acid ◽  
Cell Line ◽  
Cancer Cell ◽  
In Silico ◽  
Cancer Cell Line ◽  
Acid Inhibition ◽  
Inhibition Activity ◽  
Vitro Analysis ◽  
In Vitro Analysis

scholarly journals Anti-Cancer Activity of Cayratia Auriculata Ethanolic Extracts Against Cancer Cell Line A549 An In Vitro Analysis

2020 ◽  
Vol 13 (2) ◽  
pp. 495-499
Author(s):  
Lalitha S Lalitha ◽  
Anusha D Anusha ◽  
Yogeshkumar Murkunde ◽  
Viji Devanand ◽  
Maheshkumar K Maheshkumar
Keyword(s):  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Anti Cancer ◽  
Ethanolic Extracts ◽  
Vitro Analysis ◽  
Cancer Activity ◽  
In Vitro Analysis

The native structure of the eukaryotic ribosome

1983 ◽  
Vol 41 ◽  
pp. 432-433
Author(s):  
R.A. Milligan ◽  
P.N.T. Unwin
Keyword(s):  
Ribosomal Proteins ◽  
Crystal Form ◽  
Native Structure ◽  
X Ray Diffraction ◽  
Eukaryotic Ribosome ◽  
Vitro Analysis ◽  
In Vitro Analysis ◽  
Resolution Structure ◽  
Stable Unit

A detailed understanding of the mechanism of protein synthesis will ultimately depend on knowledge of the native structure of the ribosome. Towards this end we have investigated the low resolution structure of the eukaryotic ribosome embedded in frozen buffer, making use of a system in which the ribosomes crystallize naturally.The ribosomes in the cells of early chicken embryos form crystalline arrays when the embryos are cooled at 4°C. We have developed methods to isolate the stable unit of these arrays, the ribosome tetramer, and have determined conditions for the growth of two-dimensional crystals in vitro, Analysis of the proteins in the crystals by 2-D gel electrophoresis demonstrates the presence of all ribosomal proteins normally found in polysomes. There are in addition, four proteins which may facilitate crystallization. The crystals are built from two oppositely facing P4 layers and the predominant crystal form, accounting for >80% of the crystals, has the tetragonal space group P4212, X-ray diffraction of crystal pellets demonstrates that crystalline order extends to ~ 60Å.

1163: Radial Dilation of Ureteral Balloons: A Comparative in-Vitro Analysis

2005 ◽  
Vol 173 (4S) ◽  
pp. 315-316
Author(s):  
Kari Hendlin ◽  
Brynn Lund ◽  
Manoj Monga
Keyword(s):  
Vitro Analysis ◽  
In Vitro Analysis
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