scholarly journals Bullous Pemphigoid- A Rare Case report

2021 ◽  
pp. 151-155
Author(s):  
Mayur B. Wanjari ◽  
Deeplata Mendhe ◽  
Pratibha Wankhede ◽  
Sagar Alwadkar ◽  
Hina Rodge
Keyword(s):  
Bullous Pemphigoid ◽  
Rare Case ◽  
The Elderly ◽  
Final Diagnosis ◽  
The Body ◽  
Clear Fluid ◽  
Case Presentation ◽  
Mucous Membranes ◽  
Rare Case Report ◽  
Subepidermal Blister

Introduction: The most severe autoimmune subepidermal blistering condition of the skin and mucous membranes is bullous pemphigoid (BP). In Europe, it is estimated to affect 1 in every 4,000 people. Currently incidence range between 2-22/1,000,000 worldwide. It primarily affects the elderly and is diagnosed using clinical, histologic, and immunologic criteria. Clinically, it appears as diffuse eczematous, pruritic, urticaria-like lesions with the later emergence of tense bullae or blistering lesions filled with clear fluid. Case Presentation: Here, we report a case of a 50- years old female patient with a complaint of itchy lesions with wounds all over the body present with an 8-month of history. A subepidermal blister with eosinophils and neutrophils infiltration was discovered on histopathological evaluation. Salt-split indirect immunofluorescence revealed linear deposition of IgG at the dermo-epidermal junction. On further investigation, using diagnostic and Interventional aids a final diagnosis of Bullous pemphigoid.

scholarly journals Extensive eye-oral-bronchial mucosal nodules with eosinopgillia: a rare case report and literature review

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Lujin Wu ◽  
Qianru Leng ◽  
Yan Wang ◽  
Daowen Wang ◽  
Danlei Yang
Keyword(s):  
Biopsy Specimen ◽  
Rare Case ◽  
Unknown Origin ◽  
Neoplastic Disease ◽  
Multisystem Disease ◽  
Case Presentation ◽  
Large Numbers ◽  
Detailed Medical History ◽  
Mucous Membranes ◽  
Rare Case Report

Abstract Background Mucosal nodules can be caused by infection, inflammation and neoplastic disease. Many noninfectious diseases, such as eosinophilia, amyloidosis, sarcoidosis, Wegener’s granuloma, langerhans cell histiocytosis etc., are associated with the formation of multisytem mucosal nodules, especially significant bronchial lesions. Detailed medical history, comprehensive metabolic profile, biopsy specimen and imaging examinations are required for differentiating among these disorders. The process of diagnosis and treatment of our patient’s mucosal nodules was challenging, which could be helpful to similar cases. Case presentation We represent a case of a 29-year-old woman with plentiful nodules of unknown origin on extensive mucous membranes. Biopsy specimen reports inflammatory lesions with large numbers of neutrophils, lymphocytes, and varying degrees of eosinophils. Treatment of anti-infection, anti-tussive and anti-allergic was ineffective, but glucocorticoid showed great improvement to her symptoms. Conclusion We experienced a rare case with plentiful nodules of unknown origin on extensive mucous membranes. She may be a specific phenotype of eosinophilia or may be a novel multisystem disease with respiratory system as the primary symptom. The diagnosis of our patient remains unclear, but tentative glucocorticoid therapy was beneficial.

Linezolid Induced Skin Reactions in a Multi Drug Resistant Infective Endocarditis Patient: A Rare Case

2020 ◽  
Vol 15 (3) ◽  
pp. 222-226 ◽  
Author(s):  
Asha K. Rajan ◽  
Ananth Kashyap ◽  
Manik Chhabra ◽  
Muhammed Rashid
Keyword(s):  
Case Report ◽  
Infective Endocarditis ◽  
Rare Case ◽  
Case Reports ◽  
Multidrug Resistant ◽  
The Body ◽  
Prior History ◽  
Skin Reactions ◽  
Rare Case Report ◽  
Multiple Drugs

Rationale: Linezolid (LNZ) induced Cutaneous Adverse Drug Reactions (CADRs) have rare atypical presentation. Till date, there are very few published case reports on LNZ induced CADRs among the multidrug-resistant patients suffering from Infective Endocarditis (MDR IE). Here, we present a rare case report of LNZ induced CARs in a MDR IE patient. Case report: A 24-year-old female patient was admitted to the hospital with chief complaints of fever (101°C) associated with rigors, chills, and shortness of breath (grade IV) for the past 4 days. She was diagnosed with MDR IE, having a prior history of rheumatic heart disease. She was prescribed LNZ 600mg IV BD for MDR IE, against Staphylococcus coagulase-negative. The patient experienced flares of cutaneous reactions with multiple hyper-pigmented maculopapular lesions all over the body after one week of LNZ therapy. Upon causality assessment, she was found to be suffering from LNZ induced CADRs. LNZ dose was tapered gradually and discontinued. The patient was prescribed corticosteroids along with other supportive care. Her reactions completely subsided and infection got controlled following 1 month of therapy. Conclusion: Healthcare professionals should be vigilant for rare CADRs, while monitoring the patients on LNZ therapy especially in MDR patients as they are exposed to multiple drugs. Moreover, strengthened spontaneous reporting is required for better quantification.

scholarly journals Large-extension osteosarcoma with involvement of multiple maxillofacial structures: a rare case report

2020 ◽  
Vol 9 (10) ◽  
pp. e1519108461
Author(s):  
Rani Iani Costa Gonçalo ◽  
Cristiane Kalinne Santos Medeiros ◽  
Humberto Pereira Chaves Neto ◽  
Janaina Lessa de Moraes dos Santos ◽  
Adriano Rocha Germano ◽  
...  
Keyword(s):  
Rare Case ◽  
Correct Diagnosis ◽  
Malignant Neoplasm ◽  
Neck Region ◽  
Primary Treatment ◽  
Histopathological Diagnosis ◽  
Anatomical Structures ◽  
Case Presentation ◽  
Head And Neck Region ◽  
Rare Case Report

Background: Osteosarcoma is a malignant neoplasm that occurs most often in long bones, with the head and neck region being rarely affected, accounting for less than 1% of all cancers in this region. Objective: To report a rare case of a large-extension osteosarcoma with emphasis on its clinical and diagnostic aspects. Case presentation: A 43-year-old woman presenting an intraoral exophytic lesion with involvement of other maxillofacial structures, such as nostril, zygoma and orbit. Despite the initial clinical diagnosis of actinomycosis, an incisional biopsy confirmed the histopathological diagnosis of osteosarcoma, showing a wide morphological variety. Conclusion: This case highlights the importance of clinical and histopathological findings for the correct diagnosis of osteosarcoma. Moreover, it shows that, although surgical resection is the primary treatment for this neoplasia, depending on the extent of the tumor and its proximity to vital anatomical structures, the most appropriate conduct is not always feasible.

scholarly journals ACQUIRED IDIOPATHIC HEMOPHILIA A IN PATIENT IN THE ELDERLY: A RARE CASE REPORT AND BRIEF DISCUSSION WITH A FOCUS ON RHEUMATIC DISEASES.

2019 ◽  
Author(s):  
JOÃO CARLOS GEBER JÚNIOR ◽  
VICTOR HUDSON DE LACERDA BORGES ◽  
ALEX HALLEY CARDOZO CEMBRANEL ◽  
HIGOR MICHELL DE MELO FALCÃO ◽  
GUILHERME HACHIYA SAUD ◽  
...  
Keyword(s):  
Case Report ◽  
Rheumatic Diseases ◽  
Rare Case ◽  
Hemophilia A ◽  
The Elderly ◽  
Rare Case Report

scholarly journals Desmoplastic Fibroma and Cemento Ossifying Fibroma of The Anterior Maxilla: A Rare Case Report

2021 ◽  
Vol 24 (1) ◽  
pp. 21-27
Author(s):  
Victor Pakpahan ◽  
Eky Nasuri ◽  
Vera Julia
Keyword(s):  
Rare Case ◽  
Histopathological Examination ◽  
Neck Region ◽  
The Body ◽  
Ossifying Fibroma ◽  
Desmoplastic Fibroma ◽  
Anterior Maxilla ◽  
Main Complaint ◽  
Rare Case Report ◽  
The Right

Tumors located in the maxillofacial part of the body were classified by WHO in 2017 and among these are intraosseous form of fibromatosis known as Desmoplastic and Cemento-ossifying fibromas. These tumors usually occur in the head and neck region, especially in the mandible and are relatively rare in the maxilla. Meanwhile, this study aims to discribe a rare case of the cemento ossifying fibroma that had been previously diagnosed as desmoplastic fibroma with a mass tumor in the anterior of the maxilla. A 22 years old female reported to the Cipto Mangkusumo Hospital with the main complaint of a lump in the right side of the upper jaw which appeared 2 years prior to the operation. In April 2017, the patient had a biopsy in Tarakan Hospital and the result was a desmoplastic fibroma. Due to the lump enlargement, the patient was admitted to RSCM in July 2019 and had biopsy incision with a diagnosis of cemento ossifying fibroma which was confirmed by the histopathological examination and histology report. The resection of the right part of maxilla was conducted alongside with reconstruction using the free fibular flap. Moreover, cemento ossifying fibroma and desmoplastic fibroma shared similar features, namely, clinical, histological and radiological features which are important in establishing the diagnosis and treatment of patient. Hence, extensive enucleation or resection is required due to the progressive nature of the tumor to prevent the potential for further recurrences.

scholarly journals Corneal erforation casused by eyelid margin trichilemmal carcinoma: A case report

2019 ◽  
Author(s):  
Liying Zhang ◽  
Zhirong Lin ◽  
Huping Wu
Keyword(s):  
Rare Case ◽  
The Elderly ◽  
Corneal Perforation ◽  
Slit Lamp ◽  
Blurred Vision ◽  
Eyelid Margin ◽  
Case Presentation ◽  
Adnexal Tumor ◽  
History Of

Abstract Background: Trichilemmal carcinoma (TLC) is a rare malignant adnexal tumor predominantly affecting the scalp, eyelids, neck and face of the elderly. Here, we firstly report a rare case of corneal perforation caused by TLC grown in eyelid margin. Case presentation: A 68-year-old female presented with two months history of unprovoked redness, pain and blurred vision in the left eye. On slit-lamp examination, a 1×2mm aseptic corneal perforation embedded by iris prolapsed was noted. After excluding other causes through examinations and case history inquiry, we speculated that the severe MGD and subsequent BKC might be the cause. In order to prevent the ulcer enlargement and intraocular infection, the patient was treated with penetrating keratoplasty immediately. However, a terrible phenomenon has aroused our concern that several small nodules gradually developed on the eyelid margin, accompanied with bleeding, burst and madarosis postoperatiely. The biopsy revealed the eyelid was involved by TLC and then the lesionectomy was performed immediately. There was no evidence of local recurrence and metastasis during 1 year follow-up. Conclusions: The involvement of eyelid margin by TLC, and subsequent BKC and corneal perforation were very rare and it has not been reported yet. The concomitant BKC can be gradually healed after rectifying eyelid margin by total excision of TLC. It is very important to offer careful follow-up to all patients.

scholarly journals Extensive intramuscular cysticercosis without any neurological involvement: A rare case report

2015 ◽  
Vol 1 (8) ◽  
pp. 313
Author(s):  
Yasmeen Shamsi ◽  
Azhar Jabeen ◽  
Sadia Nikhat ◽  
Shafia Mushtaque
Keyword(s):  
Rare Case ◽  
Incidental Finding ◽  
Subcutaneous Tissue ◽  
Taenia Solium ◽  
The Body ◽  
Neurological Involvement ◽  
Rare Finding ◽  
Systemic Involvement ◽  
Cysticercus Cellulosae ◽  
Rare Case Report

<p>Human cysticercosis is a common tropical disease which is caused by Cysticercus cellulosae, larvae of a tapeworm, Taenia solium. Cysticercosis can involve any tissue in the body; the most common affected sites are central nervous system, subcutaneous tissue, eyes, and muscles. Extensive intramuscular Cysticercosis without any other systemic involvement is a very rare finding. Here, we report a case of intramuscular Cysticercosis incidentally diagnosed by plain radiographs in a 51 year-old man who presented with osteoarthritis right knee joint and Cysticercosis was an incidental finding.</p>

scholarly journals Benign Pleural Multicystic Mesothelioma: A Rare Case Report

2021 ◽  
Author(s):  
Alireza Rezvani ◽  
SeyedehMaryam Pishva ◽  
Amirhossein Erfani ◽  
Ahmad Monabati ◽  
Bizhan Ziaian ◽  
...  
Keyword(s):  
Case Report ◽  
Chronic Cough ◽  
Rare Case ◽  
Pleural Mesothelioma ◽  
Case Presentation ◽  
Rare Case Report ◽  
History Of ◽  
The Right ◽  
Lateral Thoracotomy ◽  
Pleural Involvement

Abstract Background: Fewer than 200 benign multicystic peritoneal mesothelioma cases were reported worldwide till 2017, while its pleural involvement has rarely been reported. Case presentation: We report a 70-year-old man who presented with three months history of chronic cough. Surgical resection was performed, and the pathology confirmed benign multicystic pleural mesothelioma. The patient underwent right lateral thoracotomy, wedges resection of the right upper lobe, and parietal pleurectomy and was discharged with an uneventful postop course.Conclusion: Based on published literature to date, this is the second reported case of pleural involvement of this disease.

scholarly journals Nasolabial hamartoma: a rare case report

2020 ◽  
Vol 6 (7) ◽  
pp. 1397
Author(s):  
D. Senthamarai Kannan ◽  
G. Soundara Rajan ◽  
Veerasigamani Narendrakumar ◽  
V. K. Sathiya
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Rare Case ◽  
Surgical Excision ◽  
The Body ◽  
Nasolabial Fold ◽  
Tissue Development ◽  
Inborn Errors ◽  
Complete Surgical Excision ◽  
Rare Case Report

<p class="abstract">Nasolabial cysts are rare, nonodontogenic soft tissue developmental cysts occur in the maxillary lip and nasal alar regions. Patients usually presents with an asymptomatic soft swelling with obliteration of the nasolabial fold. Due to it's origin from entrapped epithelium in an embryonic fusion plane developmentally, this cyst is considered to be a Hamartoma. Hamartomas are non-neoplastic malformations, or inborn errors of tissue development. They are characterized by an abnormal mixture of tissues indigenous to that area of the body. Complete surgical excision is the accepted method of treatment. This report aimed to present a case of nasolabial cyst hamartoma, which is rare in presentation.</p>

scholarly journals Urinary Bladder Cavernous Hemangioma in a 3-year-old: A rare case report.

2021 ◽  
Author(s):  
Charles Odongo ◽  
raymond atwine ◽  
Martin Situma ◽  
ambrose okello ◽  
eugene ogwang ◽  
...  
Keyword(s):  
Case Report ◽  
Urinary Bladder ◽  
Cavernous Hemangioma ◽  
Rare Case ◽  
Embryonal Rhabdomyosarcoma ◽  
Bladder Tumors ◽  
Case Presentation ◽  
Rare Case Report

Introduction: Cavernous hemangioma accounts for 0.6% of bladder tumors. We present a rare case Case Presentation: A 3-year-old girl presented with intravaginal swelling, dysuria, and hematuria. She received 26 cycles of VAC for embryonal rhabdomyosarcoma. Histopathology confirmed CH. Conclusion: CH should be considered in the differentials of childhood genitourinary masses.

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